Busch Lab

ZMP

impdh1a

Ensembl ID:
ENSDARG00000042336
ZFIN ID:
ZDB-GENE-040704-15
Description:
inosine 5'-phosphate dehydrogenase 1a [Source:RefSeq peptide;Acc:NP_001002177]
Human Orthologue:
IMPDH1
Human Description:
IMP (inosine 5'-monophosphate) dehydrogenase 1 [Source:HGNC Symbol;Acc:6052]
Mouse Orthologue:
Impdh1
Mouse Description:
inosine 5'-phosphate dehydrogenase 1 Gene [Source:MGI Symbol;Acc:MGI:96567]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa16224 Essential Splice Site Available for shipment Available now
sa23234 Essential Splice Site Available for shipment Available now
sa15860 Nonsense Available for shipment Available now
sa9932 Nonsense Available for shipment Available now
sa43048 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa16224
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017619 Essential Splice Site None 544 1 16
ENSDART00000101161 None None 624 None 16
ENSDART00000137098 None None 87 None 4
ENSDART00000143519 None None 179 None 5
Genomic Location (Zv9):
Chromosome 18 (position 8277407)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 8854785
GRCz11 18 8812804
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATATTCAKCMGAAGGAAGTGTGTTCCGAAAGAGAAAGTAACTCGAGACTG[T/G]AAGTGGATTTATTTGTTTTTTCGACCTAASACGCTTTTAAAAYGAATGTT
Long Flanking Sequence:
TCTACTGCGACTTATAAAGACATTTTCCGTTTTCTCTCTCTTTTTAAATCGATTTATATCAGGTGAAACGATGCACGTTATATGCCTTCTAACACCAAAATACTAGTAAATATTTTACTTCGGTTTTTCACTCAGAATATATTCAAAAACTGGTCTCGAAAAAATGTTTAGAAACAGGTTTGAGGAGTTTTCAGTACCATCATACGATGATCATCTCTCCCTGAGATGCGAGCATGTATCATGTGACTTCAGTTCACGCTGTTGTCGGTCTGTAAACACACACAGACTGCGCGTCTCACCACGAGCCCGGAGACCCTTCATCCACAGCGGCTTTGCCCTTCAGAGCTCTGCTGCGCGGAAGGAGAGACTAGTGAACCCCGCGTTGATCCGTCACGCTCTTTAATATAAAAATGTAGCAGTCATCATGTGAGCTACTGTACATGGGGGCGAATATTCAGCAGAAGGAAGTGTGTTCCGAAAGAGAAAGTAACTCGAGACTG[T/G]AAGTGGATTTATTTGTTTTTTCGACCTAACACGCTTTTAAAATGAATGTTCTGTCATTAATGAAAGTTTTAGTACAACAGAAATTCCTAATTTTTGGTTTGAATGTATTTTAATTATATAATTGTGTCGTGTGTAATTTTGCTTTATTTTTCATCATTTAACTTACGTACAACGTCTGCCTGCCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTTTACCTGTCTGTCTGTTTGTCTATCTATTATTTTTTTCAATTATACAAACCCTCATAGATTTCCTCAGCCCAAGTTTCTGTGTAGAGTTTGCATGTTCTCTCTGTTTTCGCGTGGATTTCCACCAGGTCTTGGAACTTGTGTGTATGTATGTTTCCCAGTGATGGGTTGCAGGTGGAAGGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23234
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017619 Essential Splice Site 83 544 4 16
ENSDART00000101161 Essential Splice Site 163 624 4 16
ENSDART00000137098 None None 87 None 4
ENSDART00000143519 None None 179 None 5
Genomic Location (Zv9):
Chromosome 18 (position 8289935)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 8867313
GRCz11 18 8825332
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTCTCCAATGGACACAGTCACAGAGTCCTCAATGGCCATTGCTATGGCT[G/T]TAAGTAACATTTACAAACACATATATAAAGTGTAAATTTTCCATTTCATT
Long Flanking Sequence:
CTCTTTATTGTTCAGTTGAGATTACATCAAACATCAAATACAAAAATGTAAAATTTAAAGCACTTCACAGGACCTTTAATTAAAAAATTCTAATATATGTCAAAAGTCAAGCAGGTTTGCAATGGATAGGATTACATTTCTGGCACTTTTCAATATCTATGGTGTCCTCAAACAGTGTTGACTGTCACAGCACTCAAGAAATCAGATCATGTTAAGGATGTGATTGCTTATCAAGGCACGTGATCCAAATCGGCCGTAACCTTTGTAGACCTATGTATATCTCAATAATATAATAATTGATCATACTATAGCATCATCTACATATAACATCTGCTGTATGCTAACACATGATACACTTTCGCCTCAGATTTTCATTGGAGTCTTGTTTTACATCATAGGATTTGACCTCTGCCCTGACCCGGAAAATAACCCTGAAGACGCCACTCATTTCCTCTCCAATGGACACAGTCACAGAGTCCTCAATGGCCATTGCTATGGCT[G/T]TAAGTAACATTTACAAACACATATATAAAGTGTAAATTTTCCATTTCATTACCAGTTATTTTTCCTCATAGCTCATGGGAGGAATTGGAATTATTCATCACAACTGCACGCCTGAGTTTCAGGCTAACGAGGTCCGGAAAGTTAAGGTTAGTGAAATTAAATGTAAGAGATATAACTTTGGAGGAAGTAAAAATGTGGTTAGATTTGTAGATTTATAACTCGCAGACTTTGATAATACAGATTTTTTTGAGTTCGCGATGATAAATACTATGTTTTGTGTCATATTGGCAGAAATTCGAGCAGGGCTTCATTACAGACCCTGTAGTGATGAGTCCACGACACACAGTAGGAGATGTGTTTGAAGCGAAGGTACGGCACGGTTTCTCTGGCATCCCAGTTACTGAAACTGGAAAGATGGGCAGCAAGCTGGTGGGCATTGTTACGTCACGAGACATCGACTTCCTGTCAGAAAAAGACTATGATAGGCCACTGGAGGAGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15860
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017619 Nonsense 161 544 6 16
ENSDART00000101161 Nonsense 241 624 6 16
ENSDART00000137098 None None 87 None 4
ENSDART00000143519 None None 179 None 5
Genomic Location (Zv9):
Chromosome 18 (position 8290383)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 8867761
GRCz11 18 8825780
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTACTGAAACTGGAAAGWTGGGCAGCAAGCTGGTGGGCATTGTTACGTCA[C/T]GAGACATCGACTTCCTGTCAGAAAAAGACTATGATAGGCCACTGGAGGAG
Long Flanking Sequence:
TTCCTCTCCAATGGACACAGTCACAGAGTCCTCAATGGCCATTGCTATGGCTGTAAGTAACATTTACAAACACATATATAAAGTGTAAATTTTCCATTTCATTACCAGTTATTTTTCCTCATAGCTCATGGGAGGAATTGGAATTATTCATCACAACTGCACGCCTGAGTTTCAGGCTAACGAGGTCCGGAAAGTTAAGGTTAGTGAAATTAAATGTAAGAGATATAACTTTGGAGGAAGTAAAAATGTGGTTAGATTTGTAGATTTATAACTCGCAGACTTTGATAATACAGATTTTTTTGAGTTCGCGATGATAAATACTATGTTTTGTGTCATATTGGCAGAAATTCGAGCAGGGCTTCATTACAGACCCTGTAGTGATGAGTCCACGACACACAGTAGGAGATGTGTTTGAAGCGAAGGTACGGCACGGTTTCTCTGGCATCCCAGTTACTGAAACTGGAAAGATGGGCAGCAAGCTGGTGGGCATTGTTACGTCA[C/T]GAGACATCGACTTCCTGTCAGAAAAAGACTATGATAGGCCACTGGAGGAGGTATGTGTTTGCACATTTTTTTTCAATTTCTAATTCAGCTTGAATCATTTTAATTTAGAATGCACAACTTATAAGTAAATTAGCACAACTTTTAAGTAATAGTAAATCCTCTGCAGCCTTGAAATTAGTTAATATTATTTATTGTGTTTAGATGGAGTGACAGAAAATACTGTACATTGGCCTAAATAGATTGAGGTGTTGTGAATTTGAAGAAGAGACAAAACCAGGAGGCTTTTTGGGCCTCTTTAAAGCAGAATTCTTTAATGAGGACTCACTGTCGCTGTGGCATGCATTGAAAAATCTCTGAAACTAGTGCAGCCAGGCACTCAGTTTAAATGCATTTTTATAGGCAGTAATACATAGGTGCAAATGAAGTGCAGGGGTCAGCAAGATAAATGGCATTTGCCTAGCCCTTATCTCATCAGTATAATAGTACCTATTCACATGTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9932
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017619 Nonsense 233 544 8 16
ENSDART00000101161 Nonsense 313 624 8 16
ENSDART00000137098 None None 87 None 4
ENSDART00000143519 None None 179 None 5
Genomic Location (Zv9):
Chromosome 18 (position 8291926)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 8869304
GRCz11 18 8827323
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAGCTTGTTGCAATAAKCGCTCGTACCGATTTGAAGAAGAACMGAGATTA[T/A]CCTCTGGCCTCCAAAGACTCCCGCAAACAGCTCCTGTGCGGCGCCGCCAT
Long Flanking Sequence:
GCACATTTTTTTCTTAATTAAGTACTGTCTAGAGTACGATATTTAAAAAAAAAAGATGTGCACATGTAATCAAAACTATAGCTGAAATTATTAAAATAACCAGCTGAAAAAGTTTAGATTTTTTGTTTCCTGATGATCTCCTGATGATTTTTTTTGCTTTGTGACATTTTGAGATTATGTTTTCTTTGATAAGACTCCCGAATTTCAATAATAAGCCTGAACTTTTTGAATGCTAAATCTTCTATCCTCCAGTCAATGACAAAACGAGAAGATTTAGTGGTTGCTCCAGCTGGTGTAACATTAAAAGAGGCAAATGACATCTTACAGCGCAGTAAAAAAGGTAGACGCAATAACTTCAGTCCTGTTTATGTTGTGATGTTTACCGCAAATATTTTCATCACATCATTTTTTTCTCTCTCAGGTAAACTGCCTATAGTGAATGACAGTGATGAGCTTGTTGCAATAATCGCTCGTACCGATTTGAAGAAGAACCGAGATTA[T/A]CCTCTGGCCTCCAAAGACTCCCGCAAACAGCTCCTGTGCGGCGCCGCCATCGGCACCCGAGAGGACGACAAGTACCGGCTAGATCTGCTCATGCAGGCTGGAGTGGACGTGATCGTTCTGGTGGGTACAAAAGGGAGTAGGGGGACATAAATCTTATTCTGCCTTGATATTAGAGAGCCCCTGGGATCCATTCAGCTTGATTCATGAAACAGGGGACTTATTACAGAGAGATCATAATCCTGTCTGTTTGGTAAATTCAATTAGGACCATATTTAGGACAAAAGCTTTTACAGAACAGCATGTGTGTTATCTTAACTACAAATAGGAAAAACGAATTAGATGGTATTAGAGCACATGTGTCAAACTCAGTTCCTGGAGGGCCACATCTCTGCACAGTTTAGTTCCAACCCTAATTACACCTGATCCAACTATTTGAGTCCTCTAGACTTGTTTGATACCAAAGGTAAGCGTGTTGGAGCCGGGTTGGAACTAAACTGTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43048
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017619 Essential Splice Site 514 544 16 16
ENSDART00000101161 Essential Splice Site 594 624 16 16
ENSDART00000137098 None None 87 None 4
ENSDART00000143519 Essential Splice Site 173 179 5 5
Genomic Location (Zv9):
Chromosome 18 (position 8306525)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 8883903
GRCz11 18 8841922
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATATGTAGAGAAAAAAGGCTCATGTTTAATGCTCTGTTTGTCTTCCGGCA[G/A]TTACGAGAAACGGTTATATTGAGCCTGGCAGCAGAGGGCACCCAAGAGCT
Long Flanking Sequence:
TCTCTTCATTTATTAGGTTTTACTGTGCTCAAATTGCTTTGTCTACCCAAATTGATTAAGTTCACAGTACTCATTAGGATTAGAGTCAAACGGTTTGTTGCAGTTGTTTGAGTTACCTTAAATTTTTGGGTTTTATAGTGAAAGTCTATGAGGGGGTGCATTTCTCGGCACAACACCGGCTTGATTGCAATGGAAATCTACAGACACGTATTTTAAAAAACGCAACTAAAGGTGCATTTAGCCATGTATTTTAGATTTTTTTTCACATAAAGCTGTAAAAAATGATCAAAAGCCAAGAGTAAATAAAAATGAACAGTAAACAACTTAAAATGGACAAGTGCATGAAAAAACAAAGACTTACTTCCATGGTGCTTTTTATATTTTCACTTTTGGGTGAACTGTTTTTTTATATGGGTAATATATTTGTAAAAAAAAAAAACTCTTAATTGTATATGTAGAGAAAAAAGGCTCATGTTTAATGCTCTGTTTGTCTTCCGGCA[G/A]TTACGAGAAACGGTTATATTGAGCCTGGCAGCAGAGGGCACCCAAGAGCTGGACCTAATGTCCCGTCACCGGCCGTCACTAAACACAGCAGCTAAAAAAAAAGCCATTTCTACACAACCCTCAATCCTTTGTCCTTCTTCCTGATGGCTCTCAAATCCTTGGTAAACTTAAAAAACACTTTATTGCAAGCCATCATTGGGACTAAATAACCTATGGAGCTTTTGTTTCATAGCTGCATTTTTGTTTTGTTCGGGCTTCCCTAAAAAAATGTAGACTATGAATGTACTCTGAAATATGAAGATCCTATACGTGTGTGTATGTGAAACAGAGTGTATCTTATATATTTGTGGTATACAGGGTATGTTTAGTCTGTCTTGTTCCAAAGATCCTAATTAAAAACGTCTGTTGGTTTAATAGCAATAATATATGTTGAGGTGAATCATGTGCACCACATGTGTAAGTGTTATGAGTTCAGTTCTATTGAAATCTATTATGAAATG
Associated Phenotype:
Not determined