Busch Lab

ZMP

LOC100332271

Ensembl ID:
ENSDARG00000078888
Human Orthologue:
IQGAP1
Human Description:
IQ motif containing GTPase activating protein 1 [Source:HGNC Symbol;Acc:6110]
Mouse Orthologue:
Iqgap1
Mouse Description:
IQ motif containing GTPase activating protein 1 Gene [Source:MGI Symbol;Acc:MGI:1352757]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa41010 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa7084 Nonsense Mutation detected in F1 DNA Not yet available
sa11898 Essential Splice Site Available for shipment Available now
sa15628 Essential Splice Site Available for shipment Available now
sa41009 Nonsense Mutation detected in F1 DNA Not yet available
sa34178 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa9487 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa41010
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110283 Essential Splice Site 154 1655 5 37
Genomic Location (Zv9):
Chromosome 7 (position 52165618)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 50435458
GRCz11 7 50708240
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGACAGGAAGAACATGCCACGCTGTATCTATTGCATACATGCTCTCAGG[T/A]AATCTAATATGTCACTGTGGGCTCATTCAGAAAACTCGTGTTAGGGAGCA
Long Flanking Sequence:
CGGCGTTTATCTGGCCAAGCTGGGAAACTTCTTTGCCCCCAATGTGGTCTCTCTCAAAAGAATCTATGACCGTGAACAAACACGCTACAAGGTGAGACTGACTTTATTTCTTTCAGGAGCTCTGACGGAAATAGCAGACGGTTTGAATTAAAATGTTACTCCTTTCTTTTCCCCCCTCTGCTTTGTCTTGTTTGTAGGCCACTGGGCTCCATTTCAGACACACAGACAATATCATCCAGTGGCTGAATGCAATGACAGATAAGGGCCTCCCTAAGGTGAGTCTGCATGGATCTGTCATTAGCGGCATTTCTTCAGCTTTACCGAGACATGACAGAGCTTGCCTCTCAGCTTCTTCTCCATGTTTGGCAACAGTGCTGCCTTCGGTCTCATCAAAGTACATGTTTTTTGTCTCTCCACGTTAGATTTTCTATCCTGAGACAACAGACATCTATGACAGGAAGAACATGCCACGCTGTATCTATTGCATACATGCTCTCAGG[T/A]AATCTAATATGTCACTGTGGGCTCATTCAGAAAACTCGTGTTAGGGAGCAGCCAACTATAATGCTGGGTTCACACACCAGACGGGAAGCATCTCAACATTGCTCTAGATTACTTGCTGGGGAGTTTTTTTTTCGCCTCACACTAATTTTCTGCTCAAGTTTATTTTAAATCATTTATTTATTTATTTTTTACTTATGGTGAATTGGACGTGTTCAGTTTCACGTCATTCACACCACCCGATGGAAATTCGCCCCCATTCTTGCATTTGCATTGTCTACTCATGTGAATACTTCAATATGTATTGGTAACACTTAATGTCAGTTAATGCAGTTACTAACATCAACAAAGAATGAAAGATAAGTTTGTTATAGTAACCTTTATTAGGCTTTGTTAACATTTTAATGAAGATTAAGTTGTTAGTTGTTGTTAACTCACAGTGCTTTAACTAATGTTAACAATCATAAGTTTGGGATTTTAATAATGCATTATTTAATCAGGCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7084
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110283 Nonsense 186 1655 7 37
Genomic Location (Zv9):
Chromosome 7 (position 52159909)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 50429749
GRCz11 7 50702531
KASP Assay ID:
554-4428.1 (used for ordering genotyping assays)
KASP Sequence:
TGAGTCTGTCYTTTATCTTTTCAGAGGAGGAGATCAACAAMATGAAGATC[G/T]AATTAGAGAAATACAACATTCAAATGCCAGCCTTCAGCAAAATCGGTGGR
Long Flanking Sequence:
GACTTTCTGTTTTCTCTATAGCCTCTACCTGTTTAAACTTGGTCTTGCGCCCCAGATTACAGACCTGTATGGCAAGGTCGCCTTCACAGGTGAGTCAACTCATCACGGTATTAAACTAAGCCTGGATTTTATATGGTATGATCTGGAAAGGCTGCTGTTCCTGGGAGCTGTGTTCAATGTGAAAAGCATTATCAATTGTTTGAGGGTTTCCTGCCATTTTGGCTGGCTCAAACCGCCTGCCAAGTCCCTGGATGGAGAACATTATTTACCAGACTTGCTGAGAACAATGTCCAGCCGACTCCATCAAAGAGGGGAAAAACGCTCAGCTGAGATTACCTTCTAAAAGGTTACCCAGCAGAATTTATCCAGAGTCATACAGTATAAAATAATAAAAACCTAATTCATAACATAAAGCCAAATAATCACCATTTTCACTAATATTTGCAATGCTGAGTCTGTCCTTTATCTTTTCAGAGGAGGAGATCAACAACATGAAGATC[G/T]AATTAGAGAAATACAACATTCAAATGCCAGCCTTCAGCAAAATCGGTGGGATTTTAGCCAACGAGTTATCAGTGGACGAAGCAGCCTGTGAGTTTCACGCTTTCAAAAGTCAAATTCCTCTTGGCTCTTTGGCACAGATCCTTCCCGCGCAAACAATAAACTACTAGACTTAACTTGTACAGCCAAGAGTTTAACAGCACAGTAATTACGATCTGTTTTACATCCCTCTGAGCTCAAAATATCTGCATTATCTTTTGTTGTAACGATTCAGTGCATGCTGCTGTGATCGCCATCAATGATGCCATTGACCATGGAGTTCCTGAGGGCACTTTAGCTGCCATGAGAAACCCGAACGCCATGTTGCTGCAGCTGGATGAAAGCGCTGCCCAGCAGTACCAGGACACCCTGTTCCAGGCCAAGAGTGAGAAAGTGGCCAACTCCCGAAAGAGAGTACGAACTGCACTCTACTATTAAGAGATTTGTTGTACTTGAGTTACTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11898
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110283 Essential Splice Site 274 1655 8 37
Genomic Location (Zv9):
Chromosome 7 (position 52159457)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 50429297
GRCz11 7 50702079
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CACCCTGTTCCAGGCCAAGAGTGAGAAAGTGGCCAACTCCCGAAAGAGAG[T/C]ACGAACTGCACTSTACWATTAAGAGATTTGTTGTACTTGAGTTACTAAGG
Long Flanking Sequence:
AGTCTGTCCTTTATCTTTTCAGAGGAGGAGATCAACAACATGAAGATCGAATTAGAGAAATACAACATTCAAATGCCAGCCTTCAGCAAAATCGGTGGGATTTTAGCCAACGAGTTATCAGTGGACGAAGCAGCCTGTGAGTTTCACGCTTTCAAAAGTCAAATTCCTCTTGGCTCTTTGGCACAGATCCTTCCCGCGCAAACAATAAACTACTAGACTTAACTTGTACAGCCAAGAGTTTAACAGCACAGTAATTACGATCTGTTTTACATCCCTCTGAGCTCAAAATATCTGCATTATCTTTTGTTGTAACGATTCAGTGCATGCTGCTGTGATCGCCATCAATGATGCCATTGACCATGGAGTTCCTGAGGGCACTTTAGCTGCCATGAGAAACCCGAACGCCATGTTGCTGCAGCTGGATGAAAGCGCTGCCCAGCAGTACCAGGACACCCTGTTCCAGGCCAAGAGTGAGAAAGTGGCCAACTCCCGAAAGAGAG[T/C]ACGAACTGCACTCTACTATTAAGAGATTTGTTGTACTTGAGTTACTAAGGGTGTTTTTTGCAATATGTACATATCATATCTCTTCAAAAACTTAGTGACTAGCATAACTAGACTGTAAAATGGGTAAAGTCTAAATTGAACATGCAGCCGGCCAAAAGTGTGATATGCACATCAATATAGCAGCATTTTTTTAAGAACACTGAATAACAATAATTAATACTTTACAGTACTGTGATTATTGTGTTTAGGGTTGGGGTGTGTGTAGGTGTTAAAAATACAATTTTATTGGGTGATTTAATAGATAGCATAAACAATACGCTGTACAACTACTGTTTTTACGTTTCTGTGATGGTTAGGTTTAGGGTTGGTGTGGTGGTAGACATTAATAAAATACAATAAATGGGAAATGTATTAAATAATATAACTATTTCTCGTTAGCTTCCATCCGCAACCATATCCAATCTAGCCACAACCTAGAAAGTTGGGTAACACTTTTTAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15628
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110283 Essential Splice Site 677 1655 17 37
Genomic Location (Zv9):
Chromosome 7 (position 52134199)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 50404039
GRCz11 7 50676821
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACCTACCAGGATGACCTGCTGCGRATTAAAGACGACAAGAGAAAGGAAG[G/A]TGAGATGGGCTCTTCTGTTGATTYTTTAATATYTGGTACWAAACAAGTAT
Long Flanking Sequence:
AAACATAATTGTTGTTTTTTTCCTTTTTATAATAGTTTTTTTTTCTTTCTTTTCTTTTTTCCAGGAATCTGGAGATCCATCTGCGGTGCTTTGGCTAGATGAGATTCAGGATGCAATCCTGAGAGCCAACAAGGACTCAGAGGAAGCTCTGCAGTGTAATGCTTATTAAAATCTTTATTCATTTAGCCTCTCTGTTTATCTCTTTATCTCTTTGTCTTAATAAATATCTATAACATATATTAAGATATAACATATTTTAATATATAACAGGTGATTCTTTTCTTTAAATTATGTCAGCTTTTTTCTAAAGAATGATCTTTGTCTGCCTTCAGTCTCTCAGGCGATCCAGGCCATTAATGAGGCTGTAGATAATAAGGACTCTTCTCAGACACTGGCGGCCTTGCGATCCCCTGCTGCTGGCATGTATGGAGTCACATCTGAATGTGCTCAAACCTACCAGGATGACCTGCTGCGAATTAAAGACGACAAGAGAAAGGAAG[G/A]TGAGATGGGCTCTTCTGTTGATTCTTTAATATTTGGTACTAAACAAGTATTGCCATATTTATGTTAAAATAACTGACATTTGTGCTAATTTTCTCAAAAGATGAAGATAAATATCCTTATCACAAGCTCTTGGTGACTATATATTGTTATCATGTAATAGTAATACTATACTATGAGTTTGTCTAAAACTATTTTCTGTTTACATACAGTTGAAGTCAGAGTTATTAGCCTCCCTGAATTATTAGCCCCCGTTTAATTTTTTCCCCAATTTCTGTTTAACGGAGAGCAGATTTTTTCAACACATTTCCAAACATAATAGTTTTAATAACTCATTTTTAATAACTGATTTATTTTATCTTTGCCATGATGACAGTAAATAAAATTTGACTAGATATTTTTCAAGACACTTCTATACAGCTGAAAGTGATATTTAAAGGCTTAACTAGGTTTACTAGGCAGGTTAGGGTAATTAGGCAAGTTATTGTATAATGATGGTTTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41009
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110283 Nonsense 1253 1655 28 37
Genomic Location (Zv9):
Chromosome 7 (position 52111383)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 50381223
GRCz11 7 50654005
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACAAGATGTTCCTTGGAGACAACGCACATTTGAACCCCATCAACGAATA[C/A]CTCGCCAACTCCTACCAGAAATTTAGGTAAAAGTGATATCAGTGCTTCTG
Long Flanking Sequence:
GCAGTGGAAGCCATTACAATGAATGGGTTTCATAGCGCAGAACTTTCCTTGTCTGGTGTGAAAGCTACTTTACACTGCAGTGACTATAGCTAGTGGTACTGTGAAACAAGTGCACTGAACATTACAGCATTTAAGTATAGTCTTTATTCTGTTCATTTTTTTTGCCAAAGCATTAAATCCATTTTCTGCCAATAATTTTTAGTGCGTCCATCATAGAAACAGCATTTTTTTAAACTGCATAGCTTTTGTATTTACTTGAAAATGAAAACATGGCCATGTTTCTCATTCTTTAAGATTGTGGGCAACCTGCTTTACTACCGTTACATGAATCCTGCCATTGTGGCTCCTGATGCGTTTGACATCATCGATATATCAGCTGGGGGTCAGCTGACCACAGAACAGAGGCGAAATCTGGGGTCAATCGCCAAAATGCTGCAACACGCAGCCTCAAACAAGATGTTCCTTGGAGACAACGCACATTTGAACCCCATCAACGAATA[C/A]CTCGCCAACTCCTACCAGAAATTTAGGTAAAAGTGATATCAGTGCTTCTGTTTGTTGTTTTCCAGTTGTTTGGTTTATAATCACTCCATACTGATGCAAGAACCCTTCTGTCTTCCAGACGTTTCTTTTTGTCCGCTTGTGACGTCCCTACTTTGGAGGACAAGTTCAATGTGGATCAGTACTCAGACGTGGTCACCTTGACCAAGCCTGTGATCTACATTACCATCGGGGAGATCATCAACACTCACACGGTAACAATCCAAGACTCATGGTATGCTTACATACCCCTTTTCTACCAAGGCTAGTTCCAAATCGTTTTTTTGACACCCAAATCACCAGCTGTGAAACAGGAAAAGTGCTTCTTAAGTAGCACCAAAACATTGCTGAGCTAGAACTAGTCATGTCAAGGGCTGAGTTGTATTCTCCATCTATACAAAGTGTTACTATGGCACACTGCATGAATGCAATGGATTTGCTGTGCGAAATAGGTTTGCTAAGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34178
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110283 Essential Splice Site 1416 1655 33 37
Genomic Location (Zv9):
Chromosome 7 (position 52108799)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 50378639
GRCz11 7 50651421
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTAAGCTTTATCAAACTTTGTAATAAAGTCAGCACTTTTATTTGAAACA[G/A]GAAGCAGAGTACCAGCGAGCTATGCAGCGGCGAGCCATTCGCGATGCAAA
Long Flanking Sequence:
ATTAATGTTACTTGTCACCCACTTATGTCACTTCAGAGATACAAGTGATAATACAACCAGAAAATTTGTCCAAAAGAATATTACTAATTGGGGAACCAGGTTTGGAGGCTATTCTCCCATGATCACCTTCCTGTAAATATCAGATGCACAACCCCCTATACAAATCACCTTTTGAATCTCATATACAGAGAAGAATGCAATTGCTTTCTAATTGAGTTTGCAAGTAATTGCTGGCTGTCTTAATTACTAGTTTCTGAAACTAGTAGAACTTGGGCATTTACTTGTTTTACTTATTCACAAATCTGCCCCTTTTGTCTTGCTCATTTAGCACCAAGAGGCTCATAGTAGATGTGATCAGATTTCAGCCAGGAGACACACTTACTGAGATTCTGGAGACTGTAGCTTCACCTGAGCAGGTACTTTAATTGCTATTTATTTTTCAAGAATGGAAGTAAGCTTTATCAAACTTTGTAATAAAGTCAGCACTTTTATTTGAAACA[G/A]GAAGCAGAGTACCAGCGAGCTATGCAGCGGCGAGCCATTCGCGATGCAAAGACCCCAGAGAAGATGAAGCAAGCCAAACCAGTTGTAGATGACAGTCTTACTTTGCAAGGCAAGAAGGACAAGATCAAGAGCAACCTGCAAAGACTGGGAGAGTTGGGCAAAGTACACCCTGAGAAGAAATACCAGGACCTAATCAATGACATCGCCAAGGTACTGTTCTTGGATGTGTCCTAGCATTTACATTCTGCATGTCAAGGGTGTCCAAACTTGGTCCTTGAGAGCTGGTGTCCTGCAAATTTTAGCTTCAACTTGTCTCAAGACACCTGCAAGGATGTTTCTAGAAAGCCTAGTAAGAACTTGATTAGTTAGCCCAGGTGTGTCTGATTGGAGTTGGAACTAAACTTTGCAGGACACCGGCCCTCCAGGACCGAGTTTAGTCACCACTGCTTTATGAGAACACAAAACTTCTAGCATTTCATTTTCACACTAAAGCAGGGGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9487
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110283 Essential Splice Site 1485 1655 33 37
Genomic Location (Zv9):
Chromosome 7 (position 52108587)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 50378427
GRCz11 7 50651209
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGTACACCCTGAGAAGAAATACCAGGACCTAATCAATGACATCGCCAAGG[T/C]ACTGTWCTTGGATGTGTCCTAGCATTTACATTCTGCATGTCAAGGGTGTC
Long Flanking Sequence:
TGAGTTTGCAAGTAATTGCTGGCTGTCTTAATTACTAGTTTCTGAAACTAGTAGAACTTGGGCATTTACTTGTTTTACTTATTCACAAATCTGCCCCTTTTGTCTTGCTCATTTAGCACCAAGAGGCTCATAGTAGATGTGATCAGATTTCAGCCAGGAGACACACTTACTGAGATTCTGGAGACTGTAGCTTCACCTGAGCAGGTACTTTAATTGCTATTTATTTTTCAAGAATGGAAGTAAGCTTTATCAAACTTTGTAATAAAGTCAGCACTTTTATTTGAAACAGGAAGCAGAGTACCAGCGAGCTATGCAGCGGCGAGCCATTCGCGATGCAAAGACCCCAGAGAAGATGAAGCAAGCCAAACCAGTTGTAGATGACAGTCTTACTTTGCAAGGCAAGAAGGACAAGATCAAGAGCAACCTGCAAAGACTGGGAGAGTTGGGCAAAGTACACCCTGAGAAGAAATACCAGGACCTAATCAATGACATCGCCAAGG[T/C]ACTGTTCTTGGATGTGTCCTAGCATTTACATTCTGCATGTCAAGGGTGTCCAAACTTGGTCCTTGAGAGCTGGTGTCCTGCAAATTTTAGCTTCAACTTGTCTCAAGACACCTGCAAGGATGTTTCTAGAAAGCCTAGTAAGAACTTGATTAGTTAGCCCAGGTGTGTCTGATTGGAGTTGGAACTAAACTTTGCAGGACACCGGCCCTCCAGGACCGAGTTTAGTCACCACTGCTTTATGAGAACACAAAACTTCTAGCATTTCATTTTCACACTAAAGCAGGGGTATCAAACTCGGTCCTAGAGAGTTTAGTTTTGGCCCCAATTAGACACACCTAAACCAGCTGATCAAGCTCTTTTTAGGTATGCTAGAAACCTCCAGGCACAAGTTTTGAAGGGAGTTGGAGCTAAACTATGCAGGACAACGACCCTTCAGGGCCGAGTTAGGGCACCCCTGCACTAAAGCATCTTCATTTACTTGTTAATGGTTTTTGTAGGAC
Associated Phenotype:
Not determined