Busch Lab

ZMP

huwe1

Ensembl ID:
ENSDARG00000016782
ZFIN ID:
ZDB-GENE-081104-387
Human Orthologue:
HUWE1
Human Description:
HECT, UBA and WWE domain containing 1 [Source:HGNC Symbol;Acc:30892]
Mouse Orthologue:
Huwe1
Mouse Description:
HECT, UBA and WWE domain containing 1 Gene [Source:MGI Symbol;Acc:MGI:1926884]

Alleles

There are 16 alleles of this gene:

Allele Name Consequence Status Availability
sa618 Essential Splice Site Available for shipment Available now
sa37739 Nonsense Available for shipment Available now
sa15608 Essential Splice Site Available for shipment Available now
sa24357 Nonsense Available for shipment Available now
sa17915 Essential Splice Site Available for shipment Available now
sa24358 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa618
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006657 Essential Splice Site 231 4569 7 80
ENSDART00000146990 Essential Splice Site 235 4474 7 79
Genomic Location (Zv9):
Chromosome 23 (position 28740634)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 28571201
GRCz11 23 28497742
KASP Assay ID:
554-0528.1 (used for ordering genotyping assays)
KASP Sequence:
GTCAAGCAGTAATACGCTACACTACATTCATATCGAACAACTTGATAAGG[T/C]GAGTTTCTGGGGTTTACATTTGCTGTCCTTGTGGAACAGTTAATGGAAGT
Long Flanking Sequence:
GTCACATGACTGCATTTTGGTTTTTTTAACTGGTTCAGACTAAAACAATCAGTGTGGTGTGAAAATGTCCCAAAAATGGCAGAAAAATGCTACAATGTGTCATTTATTCCCCTTTTTCTGGACCAAATGAACCGAACCACAGATGTGAAAGCCCGCTTAAACTTCATCTTGCAAGTGTTTCTTTTTTCTGAGTCGTCTGTTTTTTTGTTTTGCGCAGAAATATCCACCGAGTGCCACCACATTGCACTTTGAGTTCTATGCAGAGCCCAGCTCTGAGGTCAAAGTGGAAAAGAAGGTATGCACTGAGTCGCGCTTCCCTTTATATTGCCATTCTCTTTTTACAATGTTTTTGTTTCTTTTTTTTGTTAAGCTGAACAATTCATTTTTTTTGTTCTGTCTTGTTGTCGTGTAGACGCTTTCAACCATTTTTTTGTACCTTTTATGTCAACAGTCAAGCAGTAATACGCTACACTACATTCATATCGAACAACTTGATAAGG[T/C]GAGTTTCTGGGGTTTACATTTGCTGTCCTTGTGGAACAGTTAATGGAAGTGCATAGACGCTTAATAGCTATTGATTGCACTTGAATCTAATTTCTGCTCCTCCCCGGTGCACCCTCAGATTTCTGAAAGCCCCTCTGAGATCATGGAGTCTCTAACGGCTATGTACAACATACCTAAAGACAAGCAAATATTGCTTTTTACACACATTCGCCTGGCTCACGGCTTCTCCAACCACAAGAGGAGACTGCAGGCTGTTCAAGCCAGGCTGCATGCCATCTCCATACTCGGTGAGTGACCCCTCTGGTGCTGACCAAAATAAGAATCGGTATTTATTTTCATGAAATGGCACTAGGTTCTCGCTTTCTGTCTGGTGAGGTTGATGTAATGTGTGGTTATATTTTTTGTGCAGTGTACTCCAACGCCCTCCAGGAGTCAGCCAATAGCATACTCTATAATGGGCTTATAGAGGAGCTAGTGGATGTACTTCAGATCACAGACAA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa37739
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006657 Nonsense 423 4569 12 80
ENSDART00000146990 Nonsense 426 4474 12 79
Genomic Location (Zv9):
Chromosome 23 (position 28743691)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 28574258
GRCz11 23 28500799
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTAACCTATGCCACTTTCACATCAGGTGATCAAGTTCCTAGGGGACGAG[C/T]AGGACCAGATTACCTTTGTGACGCGGGCAGTGAGAGTTGTGGATCTCATC
Long Flanking Sequence:
CAGATTTTATTGATGAACCGTCAAAACAATTGTTGCAGGACATTAAGGCTGCTTCTTTGCGGACGTTGACATCAATAGTCCACCTGGAACGCACCCCCAAGCTCTCCAACATCATCGACTGCACAGGAACAGCCTCCTATCATGGATTTCTGCCTGTGCTTGTTCGCAACTGCATACAGGCAATGATCGGTAAGGAGATGTAAACTTTCAGCTAAGATTTCTCAACTTCAGATTCTGTATTTTTGACATTTGTTCCTGTTTTAGACCCACTGATGGAGCCGTACCCCCACCAGTTTGCCACAGCCCTCTTCTCCTTCCTCTACCACTTGGCTAGCTATGACGCAGGTGGAGAGGCCTTGGTGTCTTGTGGTATGATGGAGGCATTGCTAAAGGTTTGTAAATTGCTGCTTCCTTATTTGTTCAGCATTTAATGAGAAAGTTTTATGTGTTGTTAACCTATGCCACTTTCACATCAGGTGATCAAGTTCCTAGGGGACGAG[C/T]AGGACCAGATTACCTTTGTGACGCGGGCAGTGAGAGTTGTGGATCTCATCACCAATCTGGACATGGCCGCTTTTCAGTCCCACGGCGGCCTCTCAATCTTTATCTGCAGACTGGAGGTATTGAAACTCGTTCAGCCCCTTGTTCCTGCATAGACCATTCAGCTTTTTGCATTCTGCCCTTTTGTTGACGGAATGTGACCCCATTGTTTTTTTGTGCAGCATGAGGTTGACCTCTCCAGAAAAGAGTGCCCTTTTGTAATCAAACCAAAGATCCAGAGGCCCAGCACAGCCACTGAGACAGAGGACATGGATACAGATATGGACAGTTAGTAGTATCATCTTATTAGTGGTACCTTGCTTAGTTTATTCTTATTTAAATCTGTGTTTTGTATGCACAGACTGTGTAATCTTCACACTGGGGTTTTGTTAATGGTAATACAAGGATTATATTTTTTGCTTTTGTAAAGTCACCTTATGGAAGAGGCTCACTTCATTCCAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15608
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006657 Essential Splice Site 533 4569 14 80
ENSDART00000146990 Essential Splice Site 536 4474 14 79
Genomic Location (Zv9):
Chromosome 23 (position 28746954)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 28577521
GRCz11 23 28504062
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAGACCGATTCGCGAGCACARAGCAATGCATCCAGCACCCCAAGAGCAGG[T/C]AAAAAYACTNCCAARTACTCTAACTCACAWGTCAGTGGGTGTGYAGTTTAG
Long Flanking Sequence:
CTAATTTGGTGATTGCTTTAGATGTTCGGGCTGCAGTAAACCAGTCATCTCGTTGCTAATGGTTTTTGCTTAAAAGAAATTTAAACGGACAAAGAATAACATAACATAAAATAAATTTTAATACTGAATCATGTCTTGCCTACTTGCTCAATCACTGCTGTAAAAACTTCTATAAAATATAAGGAAAGCTTGTCAATACCCAGTCTTAAAATGAATATGTATAGAATGTCGGAGGCTTCAAAAAAAAAGATGGCAGTAAACAGTAAAATTAGTCTGTATGACATAATCCAGTTCTAAATCCATATGATTGAAGTAAAGAATTAGGGATTGTTGCTTTTCTATTTTAATGTCTGTTTTTGATGAAATTATTAAAACATGATTGTTAATGTAGTGTCCGAGGTTGCCATGGAGAGCAGTCCTGGACCATCCACTTCTTCTGGCTCCAGAGCAGAGACCGATTCGCGAGCACAAAGCAATGCATCCAGCACCCCAAGAGCAGG[T/C]AAAAATACTCCAAGTACTCTAACTCACAAGTCAGTGGGTGTGCAGTTTAGGAAATCTGGGCCATTTGTTAACATTTGTTTTTTGTTTTTGTTTTTCCTAACAGGAGTGCAGTGCATCCCTCAAAGGGCCGCTCTGTTGAAATCCATGTTAAACTTTTTGAAAAAAGCCATTCAGGACCCTGCTTTCTCTGATGGCATTCGCCATGGTATGAAACTCGTCGTATTTAATGATGATATAATTTTTACGTGATTTCTTAATAGTGTTTTTATTTGCTTTATTTGCCTCTGCGCTCTCTTTATAGTAATGGATGGGTCCCTTCCTACCTCTCTGAAACACATTATCAGTAATGCAGAGTATTATGGACCATCACTGTTTCTCCTGGGTAAGCACATTGAGGCCAGTATTTTTGCTGCCGTTGAAATATTAGCTAAGTTCCTCGTGGATATGGCTTCAAGGTCACCTCTACAAAAGAGTAGTCACTAAAGCAATATGGTTAAAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24357
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006657 Nonsense 957 4569 24 80
ENSDART00000146990 Nonsense 960 4474 24 79
Genomic Location (Zv9):
Chromosome 23 (position 28753635)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 28584202
GRCz11 23 28510743
KASP Assay ID:
2261-7913.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCATCTCTTGCTCCTCCTTTCAGAGCGAGATTCGTGCTATCTCTGTGAAT[C/T]AATGGGGATCTCAACTGGGTCTTAGTGTTTTGAACAAACTGAGTCAGCTG
Long Flanking Sequence:
TTCCACTGAATGCCCTCATGTGTCAGTTAATTTTTCTGTATTTAGTGTTTTGATTATTTTGTTTGCTCATTGTGTCCTAGACTTTATCTCATGAGCCAAAAGTCCTCCAGGAGGGTCTGTGTCAGTTGGACAGCATACTCTCTGCTCTGGAGCCACTTCACCGGCCCATTGAGGTTCCTGGAGGCTCTGTTCTGCTCAGAGAGCTGGCTAACGCAGGCCATGTCACAGACGCCACACTGTCTGCACGCGCCACCCCACTGCTGCATGCCCTCACAGCGGCACATGCGTACATCCTCATGTTCGTTCATACCTGCAGAGTCGGACAGGTACGCAAATAGGCAGCTGTTTGGAGCTCCTTCATTTAATAATTTATTTGAATAAAATTCTGAAAGTCAACAAAGTTTTGGGAATTGTAGCTTTTTAATGGAAAGACTTATGGTGGAGCTAACAGCATCTCTTGCTCCTCCTTTCAGAGCGAGATTCGTGCTATCTCTGTGAAT[C/T]AATGGGGATCTCAACTGGGTCTTAGTGTTTTGAACAAACTGAGTCAGCTGTATTGCTCTCTGGTGTGGGAGAGCACTGTGCTACTGTCCCTCTGTACACCAAACAGGTAAGGACTGCTCTCATCACAGCTGAGCCCCAAGTACACAGTAGGCTGATAACAGGTGGTCAGCCAGGGCACATTACTGTTTTCAAATGATTGAAACATGAATGATTTGGAAATTTGACAGTAGTTGTGTGTGACCTTTTTTAAAAAATAAGTGATTTGTCTTTTATTTTGCAGTTTGCCTCCTGGCTGTGAGTTTGGTCAGGCTGACATGCAGAAACTTGTGCCTAAAGAGGATAAACCTTCTAGTAGCACTGCAGCTACAGGACGGAGAACTGGTAAAATACTGCAATTTACTCTATTGTACCAGTTCATGCTTCATCCAAGTTCATGATTAAGCTCATTATTTTTTCTGCCTCCTTATTTAATATGATTTAATATATACACTTTGTTTGGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17915
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006657 Essential Splice Site 1437 4569 31 80
ENSDART00000146990 Essential Splice Site 1404 4474 31 79
Genomic Location (Zv9):
Chromosome 23 (position 28758134)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 28588701
GRCz11 23 28515242
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGAGTACCTGCTCACACACCCTCCACCACTGCTCAGCGCGGCTGTCAGAG[T/G]AAGACCCTAAYCAACACAGACAAAACCCTCWGTCTTTCTCCCATACACTC
Long Flanking Sequence:
TCAGGAACAGCCGGAGTAGTTGGAGAAGCAGTGGCTGCAGGTGCCAATGGAAACACTGCTGGAGGCTCTACAGAGGAGGCCAGCAACTCTACTACAGCACGCAGAGAGCCACAGGTCAACCAAGCTCAGCTCACACAGGTATGTCACTTCCTGTTATTAGATATTCCTGCTGCATTTAAATTTGACTTTTAAAATTCTTTTTCAAGGATTTCAAGAATTTCAAGCATTAATATTATAGTAGTATTTTTGGGCTTTGATCATTTAATTTCTTACCATAAAAAGGCCCTGTTAAGTGTATTAATATGTAATATTTGTGAACTAAGTCTTTAATATTTGAAAAAAGAGCTAATCAACCAAATCTCTACCTCTTTCACAGCTAATGGACATGGGCTTCTCCAGAGAGCACGCAATGGAGGCTTTGCTGAACACCAGCACTATGGAACAGGCCACTGAGTACCTGCTCACACACCCTCCACCACTGCTCAGCGCGGCTGTCAGAG[T/G]AAGACCCTAACCAACACAGACAAAACCCTCTGTCTTTCTCCCATACACTCATACTCACAAATACACACACACACATACATGCAGACAGGATGCACACACAAGGCATAAGCTAGTGTAGTCACTCTGAGCTTTGTTTCTGTAGGAGTTCACCATGTCTGAAGAAGACCAGATGATGCGGGCCATTGCCATGTCTCTAGGTCAAGAAGTTAGCATGGAGCAGCGCTCAGACTCACCTGAGGTGGGCACTCACACACACACACACATTATATAAAAATAGGAATAATTGAGCAGCACAGCATAGGTCACCTCACATGTCTGCTTCTCATCTTCTTCAGAAAACTTTCTCTGCCTTTAAACAGACACTCAAATCTAACCCATTCCTTTTTGTCTGCAGGAAGCAGCTCGCAGGCGTGAGGAGGAGGAGAGGAGAGCGAGGGAGCGGGTAGAGGAGGAAGAAGCTCGTTGTCTGGAGCGCTTTCTGGAAGCAGAGCCTCTTGACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24358
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006657 Essential Splice Site 4472 4569 78 80
ENSDART00000146990 Essential Splice Site 4396 4474 77 79
Genomic Location (Zv9):
Chromosome 23 (position 28807193)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 28637760
GRCz11 23 28564301
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTCAAGGCCAATACTGAATACCATAAATATCAGTCCAGTTCTATTCAGG[T/C]GTGTACACACACAATAGGATGACATGAAATAAAATATTTGATTGTTTATT
Long Flanking Sequence:
ACACAAAAATATAAATTACTTATTAAATATGAATTACAATATGAGTTTCCTTCTAACATTTTCATATTAAGAGATTTGTGATAATCTCCTCCTCATGTTATATTCACAGGTCCAAGAGTTTGGCGTGTGTGAAGTGAGAGATCTGAAGGCCAACGGTGCCAACATTCTTGTCACAGAAGAGAATAAGAAGGAATATGTGCATCTGGTCTGCCAGATGAAGATGACAGGTGAGTGCACACTCCAATAAACGTCACTGCTCCAGAGGAAGGGGAAGCTTAAAGAGTATGTCAGGAAGCTGAAACATCTATGTTTCTCAGGTGCAATCCGTAAACAGCTGGCTGCCTTCCTGGAGGGCTTTTATGAGATCATCCCCAAGAGACTGATCTCCATCTTCACTGAGCAAGAGCTGGAGCTGCTCATCTCCGGCCTGCCCACCATTGACATCGACGACCTCAAGGCCAATACTGAATACCATAAATATCAGTCCAGTTCTATTCAGG[T/C]GTGTACACACACAATAGGATGACATGAAATAAAATATTTGATTGTTTATTTTTTAATTACTGTTGTCTTCATCTTGGCACATCATTCTGAAGGTTTTATGACCTTTGCTTCAATAGTAGTGAAAGAAATTCCACGTTATCAGGCATGGAAAAGGATAGGGTTGATAGCTTTTGTATGCCAACTCAGAAGTAGGGCTGGGCGATTTGGCCTAAAATTAAAATCTCGATTAGTTGAACATTTTAACTCTTACGATTAGTGAACGATAATTTTATTTATTTATTTATTTATTTATTTAATGTTTTTGCCCTCTTAGTTCACTGACAGGTTTAATACAGTGAATATGTTCACATATTACAAGTGAGAGATTTCTGAATGAAGGGTGCATTATTTGGTTATTTGCGTGTCGTTGTGACGTGTAGTTACATTTTTTATGTGTGCAGGTATGCGAAGGCTGTGGCAGACTGTATGCGTACACTTGGCAGAAGTACAATATCAGAATT
Associated Phenotype:
Not determined