ZMP

lars

Ensembl ID:

ENSDARG00000019280

ZFIN ID:

ZDB-GENE-030114-7

Human Orthologue:

LARS

Human Description:

leucyl-tRNA synthetase [Source:HGNC Symbol;Acc:6512]

Mouse Orthologue:

Lars

Mouse Description:

leucyl-tRNA synthetase Gene [Source:MGI Symbol;Acc:MGI:1913808]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa15597	Nonsense	Available for shipment	Available now
sa39348	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa15597

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000026064	Nonsense	159	821	6	22
ENSDART00000143749	Nonsense	86	748	3	19

Genomic Location (Zv9):

Chromosome 21 (position 39709786)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	41038248
GRCz11	21	41061295

KASP Assay ID:

2261-6048.1 (used for ordering genotyping assays)

KASP Sequence:

TTTNNNNCTTTTTTTCTTNNNAGGGTGAAGCACTGATTTACATGGAGCCTGAGAAG[C/T]AGGTGTTATCTCGGTCTGCAGACGAGTGTGTTGTGGCWTTGYGTGACCAG

Long Flanking Sequence:

GGCCATAAAAGCGTACCGAAGCGAACTGTACTGCACCGTGGAAACGGGCCATAACATTTTTAATGTTTGAGCATGGGAAATTGACAACTAATGCATCAGTGGTGCTAAAAATAGCAGTCTAAACAAGTATCTACTTGCAAAGTAAGGTTGCCAGCTTCTGGCTTGGAATGTGTGCTACATTTTTAGTCATTTTCACAGATCCATGTGAAAAAGGATTGTTTTGACAACATCGTTTTCTGTGTACAAAACCTTTCTAAAATACAAAGAATTCTTCCTGATTTTAGTACATCATTGTTATGAAAATGTTCCCTAAATGAAAAATAGTACAGTTCATTTGTAGGGTAAATGACTCATTTTGAAAAATACTTATTGGTATCATTCCATTTCTTTCTTTATTTTTAAAATACAAAAACAAACTTGGTCTTACCACATTTCATTTTATGTTTTTTTTTTACTTTTTTTCTTAGGGTGAAGCACTGATTTACATGGAGCCTGAGAAG[C/T]AGGTGTTATCTCGGTCTGCAGACGAGTGTGTTGTGGCTTTGTGTGACCAGTGGTTAGTGCAGAAAACTCTCGTATGCTACATATGGTTGTACTTGATTAAGAATACCTGATGGCTTCCACTACTGTCTTGTTGTATATACAGTACACTTGCAGTTCAGTATGATTTAGTGGTGTTCTAGTACTTTTTTATTGCTATGACTTGCCTTGAGGGGTATCCCTGTTTCGTTTGAGTCACCAGACAGTGACTAGCTTTATCTGGCAGGTATCTGGATTATGGCAATGAGGAATGGAAAAAGCAGGCTCACGGTGTCCTGGAGCATCTGGAGACGTAAGTCTCACACTTTATGGCGTTGGGTGATTTACTAGAGGGCTGCTGTGTGAATACTGCTTTGCTTTTCAGGTTCTGTGATGAAACCAGAAAGAACTTTGAAGCAACGTTAGCTTGGCTTCAGGAGCACGCCTGTTCCAGAACGTATGGATTAGGTAAGACTGGCTGAAAG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa39348

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000026064	Essential Splice Site	755	821	21	22
ENSDART00000143749	Essential Splice Site	682	748	18	19

Genomic Location (Zv9):

Chromosome 21 (position 39679894)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	41008356
GRCz11	21	41031403

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AAAGACAGCATCATTCGCAGACTGTCCCGAGTCAACAGAGGCATCAAGGG[T/C]AAATCTTATTTACATTCGTTTTGGACAGAATAGAAGCTGTAAGAACGATT

Long Flanking Sequence:

TATTTTTTAATTTTGCGGATTTCCCATCCGCCATTAACAGTCCTCATCTGTTTCCTGTGCAGCGCATGTGAGTTGCTATGGAATAATAGAATTTAACACATGTTGTCTGGCGTGAGACCCACTTTATAACGCATCTCATTCAGGCAATGAAGATAATCCATTTTAAACTAGTCAGATCTTAAATTTAGCATGTTTATAATATCATGGCATTCAAGATAAATGTCCCTGTGCATGTAGCCCATTCACAAAACCAAACGTGTGTGTTAAACAAGTGAATATATGAAAATCCATTGATGACATTGATCTGTTTATTGTACCAGCCATATAAATGCATGGTGTCAACCTCGACCTGTGTCTGTCCCATAGCCTGGAGTGATAATCTCACTGGTGAACCCTCAGCCATCCAACGGTCTGTTCTCCACCAAGATAGACATCCGACAGGGAGACAGCAAAGACAGCATCATTCGCAGACTGTCCCGAGTCAACAGAGGCATCAAGGG[T/C]AAATCTTATTTACATTCGTTTTGGACAGAATAGAAGCTGTAAGAACGATTTAAAGGGTCACGAAACACCAAAACACTTTTTTTGAGCTGTTGACAGTCGTATATGTGTCCCACACTGCTGAAAACACTATTAGGACACATATATCTCACTAAAAAGTGAAAATTGGTTGTTTTTGCGTTATTTCGAGCAAATTCCTACTTCCGGTTTGAAACAAATTTTTGAAGCTGCGTCACGGCCATGAGATAATAGCGTGTATTATAGCATGTGGACTGAACGTCTGTACCAAGGCGCTCGTATTACGTCTCCGAGTGCATTGCATTCATTCATGAGTAAGGCTTGGTTTAAACCAATCAGCGCGCTCCATTATGAATGCACTGCAACTTCATTAATATGCATGCTAGCTTTCTTAGACTGGACCTGAAACAGTGTTCAGACGGCAGAGAGACAACACACGTCGTGTTGCCAAAAGTTGTGGGAAAAGAATAAGAATTGTTTGGAGA

Associated Phenotype:

Not determined