Busch Lab

ZMP

trpc6

Ensembl ID:
ENSDARG00000056625
ZFIN IDs:
ZDB-GENE-040724-114, ZDB-GENE-040724-114
Description:
short transient receptor potential channel 6 [Source:RefSeq peptide;Acc:NP_001025453]
Human Orthologue:
TRPC6
Human Description:
transient receptor potential cation channel, subfamily C, member 6 [Source:HGNC Symbol;Acc:12338]
Mouse Orthologue:
Trpc6
Mouse Description:
transient receptor potential cation channel, subfamily C, member 6 Gene [Source:MGI Symbol;Acc:MGI:1

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa23930 Nonsense Available for shipment Available now
sa37301 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa15581 Essential Splice Site Available for shipment Available now
sa10188 Essential Splice Site Available for shipment Available now
sa37300 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa37299 Nonsense Available for shipment Available now
sa23929 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa23930
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079151 Nonsense 213 855 2 11
ENSDART00000112175 Nonsense 213 874 2 12
Genomic Location (Zv9):
Chromosome 21 (position 21925673)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22774086
GRCz11 21 22810691
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGCGCTTTTCTCATGACGTCACTCCAGTCATTCTAGCCTCTCACTGTCAC[G/T]AGTACGAGATCGTGCACATACTTTTGGGAAAGGGTGCGCGCATTGAGCAG
Long Flanking Sequence:
TTCGCAGTGAGAACGTGGCCCGTCAGGTGCTGCCCAAGAGCCGCAGGCAGGCGGTGCGAGGAGCGGCTTACATGTTCAACGGCCATCCCAATAGCTTGACCCCGCTGGAGGAGCGCTTCCTCGATGCTGCTGAGTATGGGAACATCCCAGTGGTGCGTAGGATGCTGGAGGAGCTGCCGGAGCTGGACGTCAACTGTGTGGACTACATGGGCCAGAATGCACTGCAGCTCGCGGTGGCCAACGAGCACCTGGAGGTGACAGAGCTCTTGTTAAAAAAAGACAACCTGTCACGTATCGGGGATGCTCTTTTGTTGGCCATCAGCAAAGGTTACACCAGGATTGTGGAAGCCATTTTAAGCCACAAAGCTTTCGCGGACTCAAGGAGACTCACCGCGAGCCCCAGCCAGGCCCCGATGCACGATGACTTCTTCGCCTACGACGAAGATGGCACGCGCTTTTCTCATGACGTCACTCCAGTCATTCTAGCCTCTCACTGTCAC[G/T]AGTACGAGATCGTGCACATACTTTTGGGAAAGGGTGCGCGCATTGAGCAGCCTCATGATTACTTCTGTACCTGCGACACCTGTAATTATCATCAAAAGTACGATTCCTTCTGTCACTCCCGCTCGAGGATCAACGCTTACAGAGGATTGGCCAGTCCGGCTTACCTCTCTCTGTCCAATGAGGATCCAGTGTTGGCGGCCCTGGAGCTCAGCAATGAGCTCGCATCCTTGGCCAATATTGAAAAGGAATTTAAGGTATACCAGCAAGCACTTATTTTACTAAAAATTTAACTCTCGTGGTTACTTGCTCATCTTCAGCAAACACAGAGTTTCCTCTAAAACTTTCAAAGTCTCTAAAGGGTTGTTTGGCTGAAAGGCTGTAACTGAAAGAGAACCTAAAAGAGAGAATCAGAGCAATGTTCTCCTTACTTGAGGGAACATGTAATGTGTTTAAACATACATAAGCTGACTTATAGATCTTGACATACTGTATAGAACTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37301
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079151 Essential Splice Site 485 855 6 11
ENSDART00000112175 Essential Splice Site 485 874 6 12
Genomic Location (Zv9):
Chromosome 21 (position 21923359)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22771772
GRCz11 21 22808377
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTCCTGATGCAACATTCATGTATTTGTTTTCATGTCAATCTCTCTCTCA[G/A]GGATGATTTGGGCAGAGTGCAAGGAGATCTGGTCCCAAGGACCAAGAGAA
Long Flanking Sequence:
TTGTAAATTATAGCAGTGCTTAAAATATCCACCGTATCATATGAGTCATAATAATGTTGATAAACATATCAGGCTGATAATGTACGAATACACAATAGAAGAATGCAGTATTTTGTTAATCACACCACAATCAGTCTAAAATGCTGTTACCAACAGATGGGAAAGATCATGCGTGGCCCTTTCCTTAAGTTTGTGGCACATGCGGCCTCCTTTACTATTTTCCTTGGCCTTTTGGTCATGAACGCTGCCGACCGCTTTGATGGGACAAAGCTTCTTCCAAATATGACCATCCATGACTATCCGACACAGCTGTTTCGTATGAAAACAACTCCCTTCACGTGGATGGAAATGCTCATCATTTCCTGGGTCATAGGTTTGTTTCTTACTTGTTAAAGATTACTACTTAACTACAGTCTGTATTCACAGAACAAAGTGTGCAGTTCATTTGCATGTCCTGATGCAACATTCATGTATTTGTTTTCATGTCAATCTCTCTCTCA[G/A]GGATGATTTGGGCAGAGTGCAAGGAGATCTGGTCCCAAGGACCAAGAGAATATCTGCTTGAGCCTTGGAACTTGCTAGACTTTGGAATGTTGGCCATTTTTGTGGCATCCTTCATCTCAAGGATAATGGCTTTCTGGCATGCAAGTTCAGCACAACGCTATGTTGATGAGCATTACACAGATCTAACCAATGTAGTATTACCTTTTGAGGTGGGATACTTCCAGCGGGGTGAGTGAATGTCCTGACAAGTCACAAATCACACTCCAAATCAACAACAAAGCAAAATATTTTTTTTTATTTTTGTTCCAGCTCGGATTGACTGGCTTCCATCAGATCCTCAGTTAGTCTCAGAGGGCTTGTATGCCATTGCAGTGGTGCTGAGTTTTTCTCGAATTGCCTATATTCTGCCAGCTAATGAGAGCTTTGGACCACTGCAAATATCTTTGGGACGAACTGTGAAGGACATCTTCAAGTTCATGGTTATCTTCATCCTAGTCTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15581
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079151 Essential Splice Site 561 855 7 11
ENSDART00000112175 Essential Splice Site 561 874 7 12
Genomic Location (Zv9):
Chromosome 21 (position 21923051)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22771464
GRCz11 21 22808069
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CACACTCCAAATCAACAACAAAGCAAAATATTTTTTTTNATTTTTGTTCC[A/C]GCTCGGATTGACTGGCTTCCATCAGATCCTCAGTTAGTCTCAGAGGGCTT
Long Flanking Sequence:
GCTGTTTCGTATGAAAACAACTCCCTTCACGTGGATGGAAATGCTCATCATTTCCTGGGTCATAGGTTTGTTTCTTACTTGTTAAAGATTACTACTTAACTACAGTCTGTATTCACAGAACAAAGTGTGCAGTTCATTTGCATGTCCTGATGCAACATTCATGTATTTGTTTTCATGTCAATCTCTCTCTCAGGGATGATTTGGGCAGAGTGCAAGGAGATCTGGTCCCAAGGACCAAGAGAATATCTGCTTGAGCCTTGGAACTTGCTAGACTTTGGAATGTTGGCCATTTTTGTGGCATCCTTCATCTCAAGGATAATGGCTTTCTGGCATGCAAGTTCAGCACAACGCTATGTTGATGAGCATTACACAGATCTAACCAATGTAGTATTACCTTTTGAGGTGGGATACTTCCAGCGGGGTGAGTGAATGTCCTGACAAGTCACAAATCACACTCCAAATCAACAACAAAGCAAAATATTTTTTTTTATTTTTGTTCC[A/C]GCTCGGATTGACTGGCTTCCATCAGATCCTCAGTTAGTCTCAGAGGGCTTGTATGCCATTGCAGTGGTGCTGAGTTTTTCTCGAATTGCCTATATTCTGCCAGCTAATGAGAGCTTTGGACCACTGCAAATATCTTTGGGACGAACTGTGAAGGACATCTTCAAGTTCATGGTTATCTTCATCCTAGTCTTTCTGGCCTTCATGATTGGAATGTTCAACCTCTACTCATATTATCGGGGTGCAAAACAGAATGAAGCTTTCACAACGTGAGTTGAAATTATGATCTATTAGAAGTGTCTATAGTGGCAAGGGTAAAGAAGGTGAGTGGACCTTGGTGAAACAGGGTAGACCTTAGTACTTGATCTGAATCTACAGAACATTATTTTACTAAATTTAGCTAGAAGTGGTTTTGCTGAGTTTTTTTTTTTGTTGAAAGAGAAAAATATAAGGCAGAAACATGTGCCTAAAGTTAAATAAAATGTGTGGCTTTACTTGAAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10188
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079151 Essential Splice Site 781 855 9 11
ENSDART00000112175 Essential Splice Site 781 874 9 12
Genomic Location (Zv9):
Chromosome 21 (position 21918881)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22767294
GRCz11 21 22803899
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGCTTTCTGTCAGGCAAAAAGCCATTATGAAGGGGTCTGAACTCAGTGAG[G/A]TGAGGCAAATCCAYTCTTTTRCATTAAGTTRTAGTGACATTARCMATATT
Long Flanking Sequence:
CTCAACATGCTCATTGCCATGATCAACAACTCATTTCAGGAGATTGAGGTTCATCTCAGTTTCATTTCTTTAGATTTCTCTCTGAGAACTGCTGACATGATAAATCTTGAGGGTTTAGTGAGTCTTTGTGCTGATGAAGCACCCTATTGTAGTGGTTTTTGCAGACTACAAAAAAACAACCTTATCTCTTCAAAATGGGATAATTAGTTTGACTGCTTAGCAAGTTTCAAATCATCTTTTTACTGATTAAGTTGTTGCTTTATAAATTTAAAGCATCAGCACTTTCTATCATTTTCCAGGATGACGCAGATGTGGAGTGGAAGTTTGCCCGTGCCAAGCTCTGGTTCACCTACTTTGAGGAGGGCAGGACTCTCCCTGTGCCTTTTAACCTGATTCCCAGTCCCAAATCAGTACTTAGTCTGGTTATGGGGGTCAAGGGTCTCCTGCGAGAGCTTTCTGTCAGGCAAAAAGCCATTATGAAGGGGTCTGAACTCAGTGAG[G/A]TGAGGCAAATCCACTCTTTTACATTAAGTTATAGTGACATTAGCCATATTAAAGCAGAGATGTATGAAGCACACACAGAAATCACTTTCATAACAAGCAGCTTTCCTTTGGTACAATGGACAAAGTATAAACAGCTTGTTTTAGTCCCATTTCCCGCAACACACACCATAACAATCCCATTTTCGATTACCTCTGCAAGTTGTTGAACGTGGAAAAGGTCAAAATATGACTAGACTAGACAAGATTGTATTAGCAAAACTGCAGCGATAAAAAGATCTGTATTGTCCAATCATGTCAATAGCCTGCATATATATGTAGTACAGCCCACACATGAGTCAATGCCGCAAATGTGGTAGATTTATGGGCGTAGACCCATTTCAAAATGACTGAGTTTCACACACTTGCAAAGCTGCCAATCATGAAGTTTAGTGGTTTTCACCCACAATTTTTGTCAGTGATGGTAAATGTCACCAAACATTTAAAGTACACATGAAATCAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37300
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079151 None None 855 None 11
ENSDART00000112175 Essential Splice Site 782 874 10 12
Genomic Location (Zv9):
Chromosome 21 (position 21916868)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22765281
GRCz11 21 22801886
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCCATTCATATGTGTCCTGTGGTTTGTTGGGTCATTTGTTTACAATTCA[G/A]TTGGGACAGAGCAAAACTTGCCAGGCCAAGACTCTTCCACGTTCCAGTCG
Long Flanking Sequence:
TGAACTGAAGCCTAGGAGGATGCTCTTAAAGAGATTGTGATGTTGTTTGATGCCTAATATGCTTTTAATTGTTTAAATTAAACTTACTGAGTGATATTAAATTGAGGTTTACACCATATCTGCATTTTGACATCGCGGCAACAGCTGAAAGTTTGTAGTCCACAGCATGTTGTTGCAATGTTTACAGTGCTGATCCTATCCTTCTGGGTTTCTTCCCACCGCAGCCTCGCTTTCGTGTTTTATAATGGCGGCCGCATGAAACAAGAGTATGCAATGCCTACTGTACTACATTCAATCAGTTCATAGTAAAAAAAAAGTCACGTCTACTGTTTTCTCATTTAATATGCCGTTTCTCTAGGAACTGCGTCACAATAGGAAAAAAAACTGTTGCAGCTTGGAAGTTAATGTGGAAGTTAAAGTAATTAATTCATTTACGATCACAATAAACTAACCCATTCATATGTGTCCTGTGGTTTGTTGGGTCATTTGTTTACAATTCA[G/A]TTGGGACAGAGCAAAACTTGCCAGGCCAAGACTCTTCCACGTTCCAGTCGATATCAGGCATGTTTATTTCCGTTTTAATTTGCTACACTGCATATATTTAATAGATGTGAATATGGTTCATATTTCCTATTTGAATTTGAAGTCAGTTTGTAATCTGTACAGAAAATTATGAAGCGTCTTGTGAAGCGATACATCATCAAGGCTCAAAATGACAAGGAATGTGATGAAGTCAACGAGGGTGAGTGTCTGAATTTGAGGAATAATTCACAAATTTTACACACGTTCTATAACGACAGCCATCAATAGATAGAGCAATATAAAATATATTATTCCTATTTATGTATCCCACTGAATCAAAATCCCAAAGAGGATCAGCAGCAAAAGGATTCTTAGGGGAAATTTCTCTGTTAACATAATGTAAATATTTCACAATACTTGTTGCAGGTGAACTGAAGGAGATCAAACAGGACATTTCAAGCCTTCGCTATGAACTGCTGGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37299
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079151 Nonsense 796 855 10 11
ENSDART00000112175 Nonsense 815 874 11 12
Genomic Location (Zv9):
Chromosome 21 (position 21916663)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22765076
GRCz11 21 22801681
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGTACAGAAAATTATGAAGCGTCTTGTGAAGCGATACATCATCAAGGCT[C/T]AAAATGACAAGGAATGTGATGAAGTCAACGAGGGTGAGTGTCTGAATTTG
Long Flanking Sequence:
GGGTTTCTTCCCACCGCAGCCTCGCTTTCGTGTTTTATAATGGCGGCCGCATGAAACAAGAGTATGCAATGCCTACTGTACTACATTCAATCAGTTCATAGTAAAAAAAAAGTCACGTCTACTGTTTTCTCATTTAATATGCCGTTTCTCTAGGAACTGCGTCACAATAGGAAAAAAAACTGTTGCAGCTTGGAAGTTAATGTGGAAGTTAAAGTAATTAATTCATTTACGATCACAATAAACTAACCCATTCATATGTGTCCTGTGGTTTGTTGGGTCATTTGTTTACAATTCAGTTGGGACAGAGCAAAACTTGCCAGGCCAAGACTCTTCCACGTTCCAGTCGATATCAGGCATGTTTATTTCCGTTTTAATTTGCTACACTGCATATATTTAATAGATGTGAATATGGTTCATATTTCCTATTTGAATTTGAAGTCAGTTTGTAATCTGTACAGAAAATTATGAAGCGTCTTGTGAAGCGATACATCATCAAGGCT[C/T]AAAATGACAAGGAATGTGATGAAGTCAACGAGGGTGAGTGTCTGAATTTGAGGAATAATTCACAAATTTTACACACGTTCTATAACGACAGCCATCAATAGATAGAGCAATATAAAATATATTATTCCTATTTATGTATCCCACTGAATCAAAATCCCAAAGAGGATCAGCAGCAAAAGGATTCTTAGGGGAAATTTCTCTGTTAACATAATGTAAATATTTCACAATACTTGTTGCAGGTGAACTGAAGGAGATCAAACAGGACATTTCAAGCCTTCGCTATGAACTGCTGGAGGAAAAGTCACACAACATGGAGGAGCTGGCGAAGCTAGTCAGGACACTTGAAAAAAACCTCTCTCAGGACTGCTTGGTTATGAAGTCTCACTGAGAAAGTCAGACAGCTGTGTTTTGATTCTATGAGGCATAGAATCAACTATTTATCAAGCAAGATATTTTGCACAAAGACTATGTGGCTTCACATGATTCTCTGCCTTGGCCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23929
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079151 Nonsense 799 855 10 11
ENSDART00000112175 Nonsense 818 874 11 12
Genomic Location (Zv9):
Chromosome 21 (position 21916654)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22765067
GRCz11 21 22801672
KASP Assay ID:
2261-5587.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAATTATGAAGCGTCTTGTGAAGCGATACATCATCAAGGCTCAAAATGAC[A/T]AGGAATGTGATGAAGTCAACGAGGGTGAGTGTCTGAATTTGAGGAATAAT
Long Flanking Sequence:
CCCACCGCAGCCTCGCTTTCGTGTTTTATAATGGCGGCCGCATGAAACAAGAGTATGCAATGCCTACTGTACTACATTCAATCAGTTCATAGTAAAAAAAAAGTCACGTCTACTGTTTTCTCATTTAATATGCCGTTTCTCTAGGAACTGCGTCACAATAGGAAAAAAAACTGTTGCAGCTTGGAAGTTAATGTGGAAGTTAAAGTAATTAATTCATTTACGATCACAATAAACTAACCCATTCATATGTGTCCTGTGGTTTGTTGGGTCATTTGTTTACAATTCAGTTGGGACAGAGCAAAACTTGCCAGGCCAAGACTCTTCCACGTTCCAGTCGATATCAGGCATGTTTATTTCCGTTTTAATTTGCTACACTGCATATATTTAATAGATGTGAATATGGTTCATATTTCCTATTTGAATTTGAAGTCAGTTTGTAATCTGTACAGAAAATTATGAAGCGTCTTGTGAAGCGATACATCATCAAGGCTCAAAATGAC[A/T]AGGAATGTGATGAAGTCAACGAGGGTGAGTGTCTGAATTTGAGGAATAATTCACAAATTTTACACACGTTCTATAACGACAGCCATCAATAGATAGAGCAATATAAAATATATTATTCCTATTTATGTATCCCACTGAATCAAAATCCCAAAGAGGATCAGCAGCAAAAGGATTCTTAGGGGAAATTTCTCTGTTAACATAATGTAAATATTTCACAATACTTGTTGCAGGTGAACTGAAGGAGATCAAACAGGACATTTCAAGCCTTCGCTATGAACTGCTGGAGGAAAAGTCACACAACATGGAGGAGCTGGCGAAGCTAGTCAGGACACTTGAAAAAAACCTCTCTCAGGACTGCTTGGTTATGAAGTCTCACTGAGAAAGTCAGACAGCTGTGTTTTGATTCTATGAGGCATAGAATCAACTATTTATCAAGCAAGATATTTTGCACAAAGACTATGTGGCTTCACATGATTCTCTGCCTTGGCCTGCTGGTTTGA
Associated Phenotype:
Not determined