ZMP

tnnc1a

Ensembl ID:

ENSDARG00000011400

ZFIN ID:

ZDB-GENE-030523-1

Description:

troponin C, slow skeletal and cardiac muscles [Source:RefSeq peptide;Acc:NP_852475]

Human Orthologue:

TNNC1

Human Description:

troponin C type 1 (slow) [Source:HGNC Symbol;Acc:11943]

Mouse Orthologues:

AC154446.1, Tnnc1

Mouse Descriptions:

troponin C, cardiac/slow skeletal Gene [Source:MGI Symbol;Acc:MGI:98779]
troponin C, slow skeletal and cardiac muscles [Source:RefSeq peptide;Acc:NP_033419]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa25192	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa15521	Essential Splice Site	Available for shipment	Available now
sa14726	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa25192

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000023537	Essential Splice Site	8	161	1	6

Genomic Location (Zv9):

Chromosome 23 (position 4946491)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	4955190
GRCz11	23	4890775

KASP Assay ID:

554-7633.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CGGCACTTCATCTGATCTTCTCACAATGAACGACATCTACAAAGCAGCGG[T/A]GAGTCTTGGGTCTTTTTTCGTGCTTTGAGTTTTAAACAAAGTTTCACAAT

Long Flanking Sequence:

AAAATAGAATTTTTTTAACAATAGGATTTCTTCATAGTGTTGATATTAAATAGGAAGTACTGATTAAGTGTGGTTTCTTTATCATTGGAGCATACAGCAGTCAGCTGAGTAGTGGAGTACTTGGAGGTGAGTACAGGTGTACAGTTTCCCTCAGCATATCCTCCTCACATATAGCTATTCTGCCTTCCTCATGTTGTTGCTGTCTTTCCTGCTTTAAATTTTTACAGATTACGTTTTGTTTGATAGTATGTATACTGTACATGTATATTATGAATATATAATAGTTTTTTTTGTCTATCCAATTTTAACTAAAGCCTAGTCATAAACAAATAGCTGTTCTATCAGGCTTATGTGACAGTGATGGACCATCCCACACTGAGGTGGGCAGGAAGGAGCAGGCGGTCTCTCTATAAAGCTCATTTGGTTTTGTGTCCTGGTCTCCACTAGTGTCGGCACTTCATCTGATCTTCTCACAATGAACGACATCTACAAAGCAGCGG[T/A]GAGTCTTGGGTCTTTTTTCGTGCTTTGAGTTTTAAACAAAGTTTCACAATATACAAGCGCATATAGTGGGCTAAGAAATAGTTTTCATTTTCATTTATACTTTTAACTACAGTCATATAACGTATCATACTTTGTATTCATGGCTTAGCTTAAAGGAGTACTCCTTTTATTTTTGACACTGTATTGTTGAAGATTAAACTTTTTGGAGAAAGATTTAAATGTAATATTGAAATAATAATAATAATTGGTAAGTGGCAGGATGTTAGTAGTGTTATTTCTCACTTATTGAAATAAATGGGATTATTATTCACCAATAATTTGTTTACATTTTAGACGTCTCCGACATTTATTAAACCTAAAGGCAAAATGAGAGAAATTATATACTGATACAGTTATATATACATACCTGTGTCATAATCCTGCATACACTAATTAAATATGATGCAGCTTCAATGTAAAAACAGGCATTTTCACCCATCTTACCCTATTTGGACATGTCA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa15521

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000023537	Essential Splice Site	106	161	4	6

Genomic Location (Zv9):

Chromosome 23 (position 4950413)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	4959112
GRCz11	23	4894697

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

AAAGGAAGGCCWGAGGAAGAACTGGCGGAACTCTTCCGTATGTTTGACAA[G/A]TRCGTCTGTCTTTACACCAAATTCCRAGAGCAAACTGGTGTTGGGTTTAA

Long Flanking Sequence:

CTTAGCTGGTCAGGCTAGGAGATGACCAGCTAAAACCAGCTTGACCAGCCTAGGCAGGTTGAAAGCCCAGCCAAAACCAGCTATGTCCAGCCCAAACCAGGCTGGTCAAGCTGGTTTTAGCTGGTCATTTTCCAGCATGACCAGCTAAGACCAGGCTGCAAATGGTTGGAAACCAGCCTGAAACCCCTGTTGGCTGAAACCCCTCTAAAATCAGGCTAGTAAACCAGCTAAAACCAGCCTAGGCTGGTTTAAGCATTTTTTTTTTGCAGCAGGGGCCTGAAGCTGAGATATCACTGTTGTTAAATGGCTGTTAAGATAATGTGATTTTTCAGTTTGCTGGGTCAGTTTTAAAAATTTAAAAGAAATGTTGGTCGTTTTCATACAGGAAGTGGTACGGTGGATTTTGAGGAATTTTTGGTCATGATGGTGAGGTGCATGAAAGATGACAGCAAAGGAAGGCCAGAGGAAGAACTGGCGGAACTCTTCCGTATGTTTGACAA[G/A]TACGTCTGTCTTTACACCAAATTCCGAGAGCAAACTGGTGTTGGGTTTAAAGGCTTCTGATTGCATTTGATTGCATCTGGACAGGAATGCAGATGGTTACATTGACCTTGATGAACTGAAGCTAATGCTGGAAGCTACAGGTGAAGCCATCACTGAAGATGACATTGAGGAACTGATGAGGGACGGAGACAAAAACAATGACGGAAAAATTGATTATGATGGTAAGCATGTGTTTTTATTTATACTCTACTCAAATCCACTCACAATAAAAAAGAAAGATAGAAAAGAGATTAATTATTATATGGACCACTGGCCATCTACTTTTTTTTTTTTTTTAAACTCTGTTACCACTGGCTACAAGGCTAGTGTCGTCCTTAAATAGAAAAGTTATAAAAGCCTTTCAAATAAAGGTATCTAAGGTTCAGAATAGTCCATTACTTTTTAGTAAACGTCTCAGCCCTGATATCAGGAGTGCCCATTTTTTGGTATGATGGGATACT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa14726

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000023537	Nonsense	146	161	5	6

Genomic Location (Zv9):

Chromosome 23 (position 4950616)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	4959315
GRCz11	23	4894900

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

CTGAAGATGACATTGAGGAACTGATGAGGGACGGAGACAAAAACAATGAC[G/T]GAAAAATTGATTATGATGGTAAGCANNTGTTTTTATTTANNNNNNNNNNN

Long Flanking Sequence:

TCTAAAATCAGGCTAGTAAACCAGCTAAAACCAGCCTAGGCTGGTTTAAGCATTTTTTTTTTGCAGCAGGGGCCTGAAGCTGAGATATCACTGTTGTTAAATGGCTGTTAAGATAATGTGATTTTTCAGTTTGCTGGGTCAGTTTTAAAAATTTAAAAGAAATGTTGGTCGTTTTCATACAGGAAGTGGTACGGTGGATTTTGAGGAATTTTTGGTCATGATGGTGAGGTGCATGAAAGATGACAGCAAAGGAAGGCCAGAGGAAGAACTGGCGGAACTCTTCCGTATGTTTGACAAGTACGTCTGTCTTTACACCAAATTCCGAGAGCAAACTGGTGTTGGGTTTAAAGGCTTCTGATTGCATTTGATTGCATCTGGACAGGAATGCAGATGGTTACATTGACCTTGATGAACTGAAGCTAATGCTGGAAGCTACAGGTGAAGCCATCACTGAAGATGACATTGAGGAACTGATGAGGGACGGAGACAAAAACAATGAC[G/T]GAAAAATTGATTATGATGGTAAGCATGTGTTTTTATTTATACTCTACTCAAATCCACTCACAATAAAAAAGAAAGATAGAAAAGAGATTAATTATTATATGGACCACTGGCCATCTACTTTTTTTTTTTTTTTAAACTCTGTTACCACTGGCTACAAGGCTAGTGTCGTCCTTAAATAGAAAAGTTATAAAAGCCTTTCAAATAAAGGTATCTAAGGTTCAGAATAGTCCATTACTTTTTAGTAAACGTCTCAGCCCTGATATCAGGAGTGCCCATTTTTTGGTATGATGGGATACTACTTTATACATATGTTACAGTTTTCCTACAGTGGCATTATAGCGCCCTATTTGATGCAAATCCTTTCTTGCCTTTGCCTCATGGGTTTCCTTCTATTGCAGAGTTCTTGGAGTTCATGAAGGGGGTGGAATAGATGATGAAGGAATGTCTTCCTGGTGTTTCTCCTTGTGGATTGACTACACACACATTTCGTTTTATTTTCA

Associated Phenotype:

Not determined