ZMP
PPP2R2A (2 of 2)
Ensembl ID:
Description:
protein phosphatase 2, regulatory subunit B, alpha [Source:HGNC Symbol;Acc:9304]
Human Orthologue:
PPP2R2A
Human Description:
protein phosphatase 2, regulatory subunit B, alpha [Source:HGNC Symbol;Acc:9304]
Mouse Orthologue:
Ppp2r2a
Mouse Description:
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform Gene [Source:MGI Sy
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa45309 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa15515 | Nonsense | Available for shipment | Available now |
| sa34290 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa21187 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa45309
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000028983 | Essential Splice Site | 35 | 455 | 2 | 9 |
Genomic Location (Zv9):
Chromosome 8 (position 5477089)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 5182369 |
| GRCz11 | 8 | 5259868 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGTGCTTTTCAATAATTCATGATTGTGTGTGTATATGTATGTGTGTGTC[G/A]CAGCTGACATCATCTCTGCGGTGGAGTTCAATCATTCTGGGGAGCTTTTG
Long Flanking Sequence:
TTTATGCTTAGGTAATGTTAGTAAATGCATTAACTAATGGACCATTCTAAAGTGTTACCAATAATGTAATTAGGCTCTAGTTAGTGTTTCATTTGTGCTTTGACTCCGAATTCCATCTGTTTGCATCAAAAATATGTTTCATTTGTGTTTACTTGAGATTAAATTGTGCATGTGTTGTAAGCAAAGGATTTGTTCTCTGCATTGAGTCAGATCATGGCACAGCCCAGCACAGCACTGCTGCCCGTCACAATTATACGACAGAGAAAGAAAGAGAGATAGATTGTTATTCTTAGTGAACGGCGGGATGGGGGTTTGTTGGATGGCACTGTGTGTGCAGATGCCCGAGATGCTTTTAATGCCAGGCTCCGCATGTTCCCGCCCACACGCGCACAAATACAAGCAGTCGCTTATCTCCTCAGAAACATTCAGCCAAACAATATGGTCTCATAGTTGTGCTTTTCAATAATTCATGATTGTGTGTGTATATGTATGTGTGTGTC[G/A]CAGCTGACATCATCTCTGCGGTGGAGTTCAATCATTCTGGGGAGCTTTTGGCCACAGGAGACCGAGGTGGAAGAATAGTGATCTTCCAGCAAGAGCAAGAGGTGAGATGGATTACAGTTCATTAAGCACAACAATTAAGGCGTGGAGAAAAAATCGGCTGTTCATACTTGATAATGTTTTTTTTTTTAATGCAAAAGCAGACAAATAAAGCATATTCTACATATGCAGTATTGGCACCTCTTTGTGTTTAGTGTAGGGCTGTCCACACTATTTGTTGTGTGATGTGTTGCACCAAAAGTAATAGGGGTATGTTATAATATTGACATTTTAGGATAAATTTATGCCACTCATTATGTAATGACAGTATGGCTACTAGGGTTGTCACGATTCTGGTATTCGGTACCAATAAATGTTGAAGTTTTAAAAACGTCCATTTCCCACTACCATTTGAGCGCTGTTGAGTAGTTCTTAAACAGCGCTGATTTGCCATTGTGTTCACA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa15515
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000028983 | Nonsense | 94 | 455 | 3 | 9 |
Genomic Location (Zv9):
Chromosome 8 (position 5472027)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 5187431 |
| GRCz11 | 8 | 5254806 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAATACAAYGTCTACAGCACTTTCCAGAGTCACGAGCCGGAGTTCGACTA[T/A]CTGAAGAGTCTGGAAATCGAGGAAAAGAKCAATAAGATCCGCTGGCTTCC
Long Flanking Sequence:
CCTCTATCGCTGTCTGTCCACTCCACAAATAGCTGGTGTGTGGTGAGCACTGGCACTGTTGTCCACTGGCTGCCGTCGCATCATCCAAGTTCGTGCTGCACACTGGTGGTATTGTGGAGAGACTCTCTCTTAAGATTGTGAAGCGCTTAGGGTGTATGGCCATACACCATAAATGCGCTTTATAAATATACATTACTTGCACTGTATAACATATAATGTTATATTGCCAATAATATAAGTTTTATTCTAGCCTAAACAAAACAAGTAAGCCTTTCTCTAGAGTAATAAATATTATAAGAAATACTGTGAAAAATGCTTTGCTCGAGGTCAAATCACTTTGTTGTAAATGTTGATAAATTGCTGACATCATTGATGATGTGCAAAAAGTAAAAAAGTAAACGTGACATCTGTGTCTTGTTCCAGAATAAGAGCCTGCCGCAGTGTCGTGCCGAATACAATGTCTACAGCACTTTCCAGAGTCACGAGCCGGAGTTCGACTA[T/A]CTGAAGAGTCTGGAAATCGAGGAAAAGATCAATAAGATCCGCTGGCTTCCTCAGAAAAATGCTGCACACTTCCTTTTGTCCACAAACGGTGAGCTGACGCACATTATTTAAATTAATCATTCATTCTTTTATTTATTTATTTTTAATTAAATGTTTTTTTTATCATCCAGCTATGCATTAATCATAACCTTTTTGTCATTGATTCAAACACACAAAGTCTTAATTATAACTGATTATGATTAGTATATTATAGCATTGATCTCAGCTGTGCACAAGTCATTTACAATTATAAAAGCGCTTTAGTTTTTTTTTCAAGCAAGATTATTTTGCCCGAGTTGCTTATGATCAAATAGTCAAAGTAGTGTAATAACTGTTTATAGTTCAGATATAAACACTGATTTATAGAGCGAAGATTAAATTTACAGTTTGAAAGTAATGTGATGTTTTTAATGAATGTTAAAGCAATTAAATTATTATTAAATTCTTAATGCGGATTCTTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34290
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000028983 | Nonsense | 370 | 455 | 9 | 9 |
Genomic Location (Zv9):
Chromosome 8 (position 5450929)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 5208529 |
| GRCz11 | 8 | 5233708 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGTGTCATTATTTCACATCTCTCTCCAGCGAGGTCATGACTGGCTCCTA[C/A]AACAACTTCTTCCGGATGTTTGAGCGTGAGGGCCAGCGAGACGTGACTCT
Long Flanking Sequence:
CCAGATTAATAACAGGAACTAAGAAAAGAGATCATATCTCCCCTGTCCTCGCCTCATTGCACTGGCTTCCTATAAAAATTCAGAGTTGATTTTAAAATCCCTAACACATGTCCTGAATAAGGGTTCATGATGTCAGATGCTCCGGGGAGTGAAATCTGAAAGCGAACATAAGATTGCGGATAAAAATAAGTTATACAACCTTCATTTGGCTTAATCCTTATCCTTTCAGATCTATTTTAGATCTTGCTTTGACGAGACCAAAATAAAGATTGGCCATTTTAATCATTAATCATTTTTACATCTTACATAGTAGGCTACCTTTTTTTTAAGTGTGCTTCACAAGGGAGTGCGGGAAGTTGCTGCTTGGTTTTGACTCCATAGCAGTTGCAATACATTCCTTTTTACATGTATATGTTTTTTTTCTTTATAAAATAAGAACTCGTTGTCTAATTGTGTCATTATTTCACATCTCTCTCCAGCGAGGTCATGACTGGCTCCTA[C/A]AACAACTTCTTCCGGATGTTTGAGCGTGAGGGCCAGCGAGACGTGACTCTAGAGGCCTCGTGGGAGAACGGCTCCCCCGGCTGCCCGCTGAAGAGCTGGCGCGTGTCCACCGGCAGCCGACGCAAGAGGAACGAGATCGGCGTCGACTGTCTGGACTTCAGCCGCAAGATCCTCTACACCTCCTGGCATCCTCAGGAAAACATCGTTGCCTTGGCGACGGTCAATAACCTTTACCTTTTCCAGGAGAAACTCAATTAGGAATTTCAAAACTGCTTCGTCCCCATTCCTAAAAGCAGGAGTCAAATGCGGGATACATGCTAATCTCGTATCCAAGCACAAACTCATAGTCTTAATATTAACCACTGTAGTACACCAAAACCTTTGGATTATTCTGTTATGTTTAATTGATACACTGTAGGCCGGAGGAAGGGATTTTTAGTTGGATTACTGTATTGGGTTCTTGCACATTGATCTGTCTGGTTTATATGGAAGCCTGTTTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa21187
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000028983 | Nonsense | 410 | 455 | 9 | 9 |
Genomic Location (Zv9):
Chromosome 8 (position 5450811)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 5208647 |
| GRCz11 | 8 | 5233590 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACGGCTCCCCCGGCTGCCCGCTGAAGAGCTGGCGCGTGTCCACCGGCAGC[C/T]GACGCAAGAGGAACGAGATCGGCGTCGACTGTCTGGACTTCAGCCGCAAG
Long Flanking Sequence:
AAGGGTTCATGATGTCAGATGCTCCGGGGAGTGAAATCTGAAAGCGAACATAAGATTGCGGATAAAAATAAGTTATACAACCTTCATTTGGCTTAATCCTTATCCTTTCAGATCTATTTTAGATCTTGCTTTGACGAGACCAAAATAAAGATTGGCCATTTTAATCATTAATCATTTTTACATCTTACATAGTAGGCTACCTTTTTTTTAAGTGTGCTTCACAAGGGAGTGCGGGAAGTTGCTGCTTGGTTTTGACTCCATAGCAGTTGCAATACATTCCTTTTTACATGTATATGTTTTTTTTCTTTATAAAATAAGAACTCGTTGTCTAATTGTGTCATTATTTCACATCTCTCTCCAGCGAGGTCATGACTGGCTCCTACAACAACTTCTTCCGGATGTTTGAGCGTGAGGGCCAGCGAGACGTGACTCTAGAGGCCTCGTGGGAGAACGGCTCCCCCGGCTGCCCGCTGAAGAGCTGGCGCGTGTCCACCGGCAGC[C/T]GACGCAAGAGGAACGAGATCGGCGTCGACTGTCTGGACTTCAGCCGCAAGATCCTCTACACCTCCTGGCATCCTCAGGAAAACATCGTTGCCTTGGCGACGGTCAATAACCTTTACCTTTTCCAGGAGAAACTCAATTAGGAATTTCAAAACTGCTTCGTCCCCATTCCTAAAAGCAGGAGTCAAATGCGGGATACATGCTAATCTCGTATCCAAGCACAAACTCATAGTCTTAATATTAACCACTGTAGTACACCAAAACCTTTGGATTATTCTGTTATGTTTAATTGATACACTGTAGGCCGGAGGAAGGGATTTTTAGTTGGATTACTGTATTGGGTTCTTGCACATTGATCTGTCTGGTTTATATGGAAGCCTGTTTCGGTCACAGGTGGATTCAAAAGCAATTCTGGCGTTTTAATTACTCAATTAAAAGTTTTTTAGGAATAGAAACTTCTGATCTCATAAAAAATCTTGTGAATTCTGAGTTTATATCACAAT
Associated Phenotype:
Not determined