ZMP

lamb2l

Ensembl ID:

ENSDARG00000033950

ZFIN ID:

ZDB-GENE-030131-4205

Description:

Novel protein similar to vertebrate laminin beta family [Source:UniProtKB/TrEMBL;Acc:B7ZDA7]

Human Orthologues:

LAMB1, LAMB2

Human Descriptions:

laminin, beta 1 [Source:HGNC Symbol;Acc:6486]
laminin, beta 2 (laminin S) [Source:HGNC Symbol;Acc:6487]

Mouse Orthologues:

Lamb1, Lamb2

Mouse Descriptions:

laminin B1 Gene [Source:MGI Symbol;Acc:MGI:96743]
laminin, beta 2 Gene [Source:MGI Symbol;Acc:MGI:99916]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa37675	Nonsense	Mutation detected in F1 DNA	Not yet available
sa15326	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa37675

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000048366	Nonsense	34	627	2	11
ENSDART00000130856	Nonsense	1015	1780	21	32

Genomic Location (Zv9):

Chromosome 23 (position 20570654)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	20355761
GRCz11	23	20282104

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ATTTCATGCATTTATATTTAACTCTGCTCTCTGTTTCATTCTACAGGATG[T/A]ACTTGTGTAACTGCAGGCACTTTGCCAAACTCTTGCACTGATGGAGTGTG

Long Flanking Sequence:

TGTCGCCCATGTCCGTGTCCAGGACACCCTGACAGTGGACATTCCAACGGTGCCTCCTGTGAAGTAGACTACGCCTCCAACCAGATCCTTTGCCAGTGTGGGCAAGGCTACGCTGGTAAAACAAGTCACTAAACCGAAAACTTTCACTTCTCAAGAAGCATCTTAACTTGCAGTGTTTTTTGTCAGGTCCTCGCTGTGATCGCTGCGCCCCCGGTTATTATGGTGACCCCGAGCACCCTGGTGGATCGTGCCGGCCCTGCCAGTGCAATGGGAACATTGACCCTCAGGACCCAGAGTCATGTGACCCTCGAACTGGACTGTGCCTCAAGTGTCTGTATAACACAGATGGAGACTCTTGCTCAGAGTGTAAACTGGGTTATTATGGAAATGCACTCATTCAGGACTGTAGGCGTAAGTGCAGTGATTCTAAAACAACAATGTTTTTAAATAATTTCATGCATTTATATTTAACTCTGCTCTCTGTTTCATTCTACAGGATG[T/A]ACTTGTGTAACTGCAGGCACTTTGCCAAACTCTTGCACTGATGGAGTGTGTCAATGTGATAAACAGACAGGACAGTGCCCCTGCAAGCAAAACATCATTGGACATAACTGTGACCAGTGCGCCACCAATCACTGGAACTTCGGCTCTGACTGTGGATGTGAACCCTGTGGATGTGTCCAACCTAATGCCCTCAGCACCCACTGTAACATGGTAGGATCTGTGCAGATAGCAATAAAGGCTTATTCTGAAAACGTAGCTCTATATACAAATCTGGAGATCCTGAATTATGTAGCCGCAGGTACATATTAAATAAGTAAGTAAATAACAATGAGAATGTGGTAAAATCTGAAAATCAGGCTGCCACAAGAGCTTTTCTTTCTCTGGATTGCTTTTAAAAACACTGTGGGTTGGGTTAAGGGAAGTGGGTGGGCGGATGGTGTGAGAAGAGCAGGTGAGAATGGCACTCGTGAGAGAAATTTGAGATCTCAAAAAGTGTACAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa15326

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000048366	Essential Splice Site	323	627	6	11
ENSDART00000130856	Essential Splice Site	1304	1780	25	32

Genomic Location (Zv9):

Chromosome 23 (position 20559369)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	20344476
GRCz11	23	20270819

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TYGTAATAAACATTGAAATGAGGTTGATGTTTTTGCTATTTCCCTTTTAC[A/T]GAGCAATYTGCAAATGTGCTGAAGTATTACCAGAGATCCCTGAATTCAGA

Long Flanking Sequence:

GAAGTTCCCCCCGAAGGGGAACTTGACCTTATAGAAATGTTATTTGCAGAATTAATTTGTTGTTTTAATATTTTTGTACCTAAGCCTGATAGTAAACAAATTACTAATAAACATAATGACTTGATCAGTTTTGCAATATACAATCAAATTGCAGACAATCAATGCATGAAATTGGTCAAAAGTGGAAAATTTCTGCAGATTGCACATCTACACTGTAAAAATTAATAATGGCAAAAAGTCATGACAATAAATGTTTTCATGTTACTTTAACTTCTGGTTTCAAGTCATTTTTATTTTAATTTATAATAATATTTTAGTCAGTCTGGATGATGTAGGTTTAGATAAAACTTTTTTTGATTCAACTGAAACATTTAAAACAGCAAGAATTTACCTGCAGTGTATGGATTACATACTCATGACTTGATTACCTTTTCATTCACACCATCATTTTTGTAATAAACATTGAAATGAGGTTGATGTTTTTGCTATTTCCCTTTTAC[A/T]GAGCAATTTGCAAATGTGCTGAAGTATTACCAGAGATCCCTGAATTCAGAGCAGCGCTGCAATGCCTCCGTATACGGACCCCAGAGTCCTGTGGAACAGTCTCAGGACACACGTAACCGTACCGAAGCCCTGCTGAAGGACAAGAAGGACAGCCTCCTGCGTACAGCCACAGCTAACAATAAATCCCTGTCTGAACTGGAGGGAAAAGCTCATGAGATCAACCGAAAGGTCCATCACCTTAGCAACAAGGTAGAGACTTTGGTTAAAACTTGACACATTCTTGTTTATGTCATGCTTTAATAGTGAAGTAGGTAGTTTTGGCACTACTAGCGTCACTTATTTGTAGGGAAGGGCATAGAAGGTTTTAACGGTATTACTACTTTTATCAATACAACTTCGGTTCAGTACTGTAACGTTTCTCTTATCTGTACTTTTTGTTGTGTTTTTTTAATGAAAAAAACAAAAAAACAAATTGAACAGAATTAAAACACTTTATTTTA

Associated Phenotype:

Not determined