ZMP
cbl
Ensembl ID:
ZFIN ID:
Description:
E3 ubiquitin-protein ligase CBL [Source:RefSeq peptide;Acc:NP_001007331]
Human Orthologue:
CBL
Human Description:
Cas-Br-M (murine) ecotropic retroviral transforming sequence [Source:HGNC Symbol;Acc:1541]
Mouse Orthologue:
Cbl
Mouse Description:
Casitas B-lineage lymphoma Gene [Source:MGI Symbol;Acc:MGI:88279]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa35879 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa42540 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa15300 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa35879
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006085 | Nonsense | 176 | 913 | 3 | 16 |
| ENSDART00000130728 | Nonsense | 176 | 913 | 3 | 17 |
Genomic Location (Zv9):
Chromosome 15 (position 22597430)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 23308617 |
| GRCz11 | 15 | 23243882 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGGGGACAACTTCAGAATCACCAAAGCGGATGCCGCAGAGTTCTGGAGA[A/T]GATCGTTCGGGGACAAGTGAGATGCTTCATGTGCTCTTAGTACCCGTAAA
Long Flanking Sequence:
TTTTTTTTTTTTTTTAAGTTTTTTTTTTTTGTTGTTGAACACAAAAGAAGATGTTTTGAAAAATGTTGGAAAATTAGCTGTTTACTGACATCCAAAGCAGCAAAATTATACCATGGAAGGCAATATACATTCTAACATTCTTTTGTAAATTTATCATCTTTAGAGAAGTAAAATGCTAATAAAAATGCTCATAATTTAGAGAAAGTGGAGCACTAACAAATAATGACAGTGTTGTCATTTTTAGGTGAACTATACCTTTAGGGTAAAAAAAAAAGATCATCTGCTGGTGTAGACTCTAATAATGTTGTAATTATAGTTCTTAGTGTAAACAGACATTATTTTCCAAATATTCTCTTTTCTTGTCTTTCAGACGGAACTTAACAAAGTTGTCGCTGATTTTCAGTCACATGCTCGCTGAGCTCAAAGCCATCTTTCCTAATGGTCTGTTTCAAGGGGACAACTTCAGAATCACCAAAGCGGATGCCGCAGAGTTCTGGAGA[A/T]GATCGTTCGGGGACAAGTGAGATGCTTCATGTGCTCTTAGTACCCGTAAAAGATTAACATGTTCTATGAAAAAACAAAACAAAAGCAAGATGGACTTTGTCATGCTTTAGAAAACTGTTTCCAATAAGCTGAATTTCTCTGAATTTCAGGACCATTGTGCCTTGGAAGGTGTTCCGTCAGGCCCTGCATGAGTTTCACCCCATCAGCTCAGGCCTGGAGGCCATGGCACTGAAATCCACCATCGACCTCACATGCAACGACTACATCTCCGTTTTTGAGTTTGACATCTTCACCAGGCTATTCCAGGTGCGTCACTCAGTCACTCCATCACTTCCTCCAAGCACAGACTAGCTCCATTGTCTGTGCGCTTGCTCTGACAATGATTATTGTTGTGTGGCTGTGGCTACGGAGGCGCCGTTGAGTGCTGATGCTTCAGTTCTCATGGCTGAATGGAGGCCTCTTATCGCCTTTTGTTGCTCAAACAGGCTTGTCTGCACTCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa42540
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006085 | Essential Splice Site | 511 | 913 | 10 | 16 |
| ENSDART00000130728 | Essential Splice Site | 511 | 913 | 10 | 17 |
Genomic Location (Zv9):
Chromosome 15 (position 22609712)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 23320899 |
| GRCz11 | 15 | 23256164 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGGCCCACCAACCCTCCTGGGGCCTCAAGTCCAGGGGCCACATCCAAGG[T/C]AAATGCTCTAGCGGGGAATGTTTGGTCAAGTTTTCTTCACTTTTGGTACC
Long Flanking Sequence:
CATGTTTGGGGCTGAGGGAGCCCCTTCACCCAGCTACGACGATGATGATGATGACCGTTTAGAGGAAACTCCTTTCATGATTAGCAAGCTGGTCGGCTCTAAAGTGAGAATAACTTTCACCTTTTTGCTAAACCTGCAATAATGTGTCCGCTTCCTCGCCTCACCTCAGTGTCGCCTGCCTCAATAAATATTATTTTTAATTAGTTTGAGGCTGCCATTTTGAAGTTTAATATAGAAATTAACCCAAATCCAAACCAAACAACTCTTCCCGCATACACTTGACCAGGTTGCGGTAAAGGTTCTGAAATTCTGGCAGGAGTATTTAGCATCAGTGGAGCTGTGTGCTGAATGGTGTGACTTGTTTCAGGTGGAGAGGCCGCCCTCGCCGATGTCAATCTCCCCTCAGCCCGTCGTTCCTCCAGTACCTCCTCGGCTGGATCTGCTTCCTCTCAGGCCCACCAACCCTCCTGGGGCCTCAAGTCCAGGGGCCACATCCAAGG[T/C]AAATGCTCTAGCGGGGAATGTTTGGTCAAGTTTTCTTCACTTTTGGTACCTCAGGTTGAAACCCATTAAGCATTTTTTAATGCATCAGAAGGAAATGATGTTCAGATGCTACTGGAGTTTTTCCTAACTGGTTTTATCCCATTCCAGGCCCCTTCCCATCACAAAGACAAGCCATTACCGCTGCCGCCGGCTCTAAGGGATCTGCCACCTCCACCTCCCCCAGACCGTCCACACCCAGCTGGAGCAGACAACCGTCTCCCAAGACGTCCTCTCCCCAGTACGCCTGGAGACCCATCTCGTGACAAACTGCCCCCGGCCCCTCCTAACCGCAACATGCCAGACTGGAACTCCCGGCCTGTACCCAAAGCCCCATCACAGCCACCAGCAAGCGGAGACACCCGTGGATCTCGAGAGCTTTCCAACAGGCACTCTCTGCCTCTCCAACTGCCCTCTACTCTCGATTCCAGAACAGAAGCCCCCAGAAACAACGGCCCTCCCAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa15300
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000006085 | Nonsense | 645 | 913 | 12 | 16 |
| ENSDART00000130728 | Nonsense | 645 | 913 | 12 | 17 |
Genomic Location (Zv9):
Chromosome 15 (position 22610345)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 23321532 |
| GRCz11 | 15 | 23256797 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATGCTTTATGTGTGCAGAGTTTTGGATCATCRAATCCTGCATCGGATTA[T/G]GACAGTCCAAAAGTAAAGCCGTCTGCCTCGGCTAATGCCATCTATTCCTT
Long Flanking Sequence:
TTTATCCCATTCCAGGCCCCTTCCCATCACAAAGACAAGCCATTACCGCTGCCGCCGGCTCTAAGGGATCTGCCACCTCCACCTCCCCCAGACCGTCCACACCCAGCTGGAGCAGACAACCGTCTCCCAAGACGTCCTCTCCCCAGTACGCCTGGAGACCCATCTCGTGACAAACTGCCCCCGGCCCCTCCTAACCGCAACATGCCAGACTGGAACTCCCGGCCTGTACCCAAAGCCCCATCACAGCCACCAGCAAGCGGAGACACCCGTGGATCTCGAGAGCTTTCCAACAGGCACTCTCTGCCTCTCCAACTGCCCTCTACTCTCGATTCCAGAACAGAAGCCCCCAGAAACAACGGCCCTCCCAGCCTCGACCACCAGCTGGTAAGGACATGTGTGCCATAAGTACACCTTGACAGAAGCAGAAACTGAATATTTATTTAACTTTCACATGCTTTATGTGTGCAGAGTTTTGGATCATCGAATCCTGCATCGGATTA[T/G]GACAGTCCAAAAGTAAAGCCGTCTGCCTCGGCTAATGCCATCTATTCCTTGGCAATACGGTAAGTGCCACACAAAGTTGAAATAAAACTGTACAATAGGTGGGTGTGTGTGTCCACCAATTTTACCTCTGTAGGTGCTTGAATGTGCTTTGGAGGCAAAGTGTTTAAATAAACCCTTGGTGAGTTAAATGTTCCTCCAACTATTATCATTATGGTTTTTATATTTTTTTTTAGTTCAGAGAAGAAAGAATAGCAGAGTGCACACCACATCTACGAGGCTAATGGCACAAGGGAGCAGTGTTGCTTTTTTGCAGTTGATGAACAATAAAACATCCATCCTGATTTTAATAAAAGCTTACACATTTAAAGCAAAGTGAACTCCACTACATGCTTATTAATATATACAGATCATTATTTTGCATTAGTAATTAGGTTGTATTTAAAATGTTTTGTTCTCTGTGTGATCAGGGATGTTTTTATTTTTTTAGTATACCCAAGTTG
Associated Phenotype:
Not determined