Busch Lab

ZMP

ret1

Ensembl ID:
ENSDARG00000055305
ZFIN ID:
ZDB-GENE-980526-307
Description:
proto-oncogene tyrosine-protein kinase receptor Ret [Source:RefSeq peptide;Acc:NP_858048]
Human Orthologue:
RET
Human Description:
ret proto-oncogene [Source:HGNC Symbol;Acc:9967]
Mouse Orthologue:
Ret
Mouse Description:
ret proto-oncogene Gene [Source:MGI Symbol;Acc:MGI:97902]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa42210 Nonsense Mutation detected in F1 DNA Not yet available
hu2846 Nonsense Available for shipment Available now
sa35492 Essential Splice Site Available for shipment Available now
sa15240 Nonsense Available for shipment Available now
sa22307 Nonsense Available for shipment Available now
sa2684 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa42210
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077627 Nonsense 59 1106 2 20
ENSDART00000139237 Nonsense 41 1046 1 18
Genomic Location (Zv9):
Chromosome 13 (position 25827659)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 25473319
GRCz11 13 25603769
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCGTTGCTTCAGGTCATTTCAATGCGGGAATTCCCTACAGAGAGGCCTTA[T/G]TTCTTCCTGTGCTCGCACAGAGACGCTTTTACATCATGGTTTCACATAGA
Long Flanking Sequence:
AACTTGTTATTAGACATTTACAGGATAAAATAGATATTAACAATCTACTCAAACCAATAAATCCTTTGTCAAGTCCTCTGCATTATTTAATCTTTAAAGTTGTTCTTGTCTATTTAATGTTCATCTGAGGTTCAGTTTTCTTGCAAACGTCCTGCGGAGTCAGATTAAATTTTTTTGACTCAAATGCTTTTGGTCTGAACTTGTATTGAACCCAGAATATCCATTTATTCCATTGTTAAAATGATGAAAGTGCTACGATTTCTTCATTGGTGATGGATGTAAAAAGTGTGTAAAGGACAGCCAAAATGTGACAATGTCTGGATCCGAAACTGAAATATTAAATCTCTGTGGTGTTATATTTGCTGTGTGTTTTGGACAGGTTCATTCGGGCTGTATTTTCCTCAAAGGCTTTACACAGAGAACATCTACGTGGGTCAGCAGCAGGGATCACCGTTGCTTCAGGTCATTTCAATGCGGGAATTCCCTACAGAGAGGCCTTA[T/G]TTCTTCCTGTGCTCGCACAGAGACGCTTTTACATCATGGTTTCACATAGATGAGGCGTCCGGAGTTCTTTATCTCAACAAAACCCTGGAGTGGAGCGACTTCAGTAGTTTACGTGAGTTCAACATATCCACTGAAAGAAATGATTCATTGGATTTACTAAATGTTTTTTAAGGTAAGTGGTTGCAAACAATTAATATGGGCTGAATTTAAAAAACAAACAAATTAAATTGAACATTACAAAATTTAATTTGCTCATTTAAAACCAGCCCATATACATAGTTTGCAATCACTTACCTTAAAAAAACATTTAGTAAAAGTATATATTTAGTTTATAGAAAGAACCATTGTAATTTTCTTCATTATTTTGCTTATATATTCTGGGTATTCTTGGATTTTATGGGTTTAAATTGTTCGTATCATTTTATTGTACTCATATATTTTATGTTATTTTAATACAATTTTAATTTACTTATAAAGTAAAATAATAAATAAATAAATCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
hu2846
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077627 Nonsense 229 1106 4 20
ENSDART00000139237 Nonsense 211 1046 3 18
Genomic Location (Zv9):
Chromosome 13 (position 25824425)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 25470085
GRCz11 13 25600535
KASP Assay ID:
554-0012.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCACAAGTGGACCGCGAGGAGAAGGAAGTGTATCATCTGGATATAGTCTG[T/A]ATGGTACGAACAGAAAGAAATCTGGAGGAGGTCTTCAGATCTTTACATGT
Long Flanking Sequence:
TTTAATGGTAGAAAATAGTTTCACATTGGGCTGTTTAGCAGAGCTCACCATGCAACAAACAAAATAAGTATTGTAAATTGATAAAAGAAGGCACATTATGCTGATTTGTTGTATATTTAATGATGTTAGATGGTTAGCTAAATGCATTTGATCAATTATAGTCAATAAATCTTTGCTAAATGTGTTTGTAAAAGCTGTTTTTGATACATTTTTGACATGGGTTTTTGTTGTATTTGCACAGATTTGACCAGCAGAGTTACTCAGTCTGTGATCATTTGAACACTTCAAAATCATTATATGAAGCAATTGGTCTAAGTCATTTAAAGATTTGGAAAACTTATTTTCTCCCGTCACTACTCTAAGATGGATTGTCTGTGCTTGTTTATATTTAATTCAGGATCTTCTGTACCGTTTGCGGTCGACGACTCCACTTCTGAACTAGTGGTCACAGCACAAGTGGACCGCGAGGAGAAGGAAGTGTATCATCTGGATATAGTCTG[T/A]ATGGTACGAACAGAAAGAAATCTGGAGGAGGTCTTCAGATCTTTACATGTGAACATCTATGATGAAGATGATAATTCTCCTTATGTCAACGGGACTGACACTGAAGACGTCTTAGTAGAGTTTGACCGCAGTGAGGTGTGTGCTATTTTGTGTGTGTGTGTGTGTGTAATCTTCTTAGCTTTTTTGATCTTGTATATTAATAAGCTTTTCTCTTTTGTAGGGTACTGTGTTTGGGACTCTGTTTGTATATGACAGAGACACAACACCAGTTTATCCCACAAACCAAGTTCAAAATAAACTGGTGGGGACCCTGATGACAAATGACTCCTGGATCAAAAATAATTTTGCTATTGAACACAAGTTTAGGGAAGAGAAAGCTATTTTTGGAAATGTCCGTGGGACTGTTCATGAATACAGTGAGTACAAAAACAGTTTTTTGCTTATTTTTAAACATAATTTTAGTGCTTTTAAAAATGTTTTTCCTCTTGGTGTTTATCTCA
Associated Phenotype:
This allele has been associated with this phenotype by genetic linkage analysis and may not be causal.
See FAQs for more info.
Control on top; Mutant below; 5 dpf
Control on top; Mutant below; 5 dpf
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
ventral mandibular arch
ZFA:0001273
quality
PATO:0000001
abnormal
PATO:0000460

Mutation Details

Allele Name:
sa35492
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077627 Essential Splice Site 619 1106 10 20
ENSDART00000139237 Essential Splice Site 601 1046 9 18
Genomic Location (Zv9):
Chromosome 13 (position 25817707)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 25463367
GRCz11 13 25593817
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTTACTGCTTTGAAGGAAAGTGCTTCTGTGAAAGAGATGAACCGGAGGG[T/C]GAGCTGCAGCTGATTGTTTTTTTCTCTGTAAAGATTGTATTTTTTATATT
Long Flanking Sequence:
CGACTCGAGGCCTGGGAGCCCCAACAGGGAGATGCCAGTGGAGACAAGGCCGAGATAAAGGTTACCCACAATCCCCTTGACTACTACAAGGACGTGCAAATCAAATACACTGCACTTTACTTTATTATTGTGTTTGCTGAAAAACTAATTCTGTGTTGTTTGCAGGAATATCAAAAAGATACTCCACCTGTTCCCCCAACCTCGGCACGTGCCCTGATGGTTACTGTGATGCCATTGAGAGCAAGAACATCTCCATCTGTCCTCAGGATTGCTCCAGTAAGACGTATTTGAGCACTTGTTTTGGTGCAGTGTTGTTTAGTTTGATCAGCATAATTGTGCAATGGTGCATTAAGGAAGTGAAATGTCTATATCTGTGTCTTTTTGTCAGGTGAGGCCATAATCGGCGGTTATGAAAGGGACCTGTATGGAATCAAAGCTGGACATGGGACCTGTTACTGCTTTGAAGGAAAGTGCTTCTGTGAAAGAGATGAACCGGAGGG[T/C]GAGCTGCAGCTGATTGTTTTTTTCTCTGTAAAGATTGTATTTTTTATATTATTTTCGGACTTTCGTAACTTCACAGAAGATAAATTAAGAAGTTCTCAAAGTTAACAGAATTGGGGATTATTTTATTATAGTTGCAAAACTTTTGTATCAGTTGTTTGTTTAGGTATTTATTTATTTTTTTATTTAAATAGACATGGACCTCACAATTACACTGGACAAGTGTTTTAGCATACTTGCTAACTCTCAACAACTATCCACAGGAGCCTTGACCTAAAATGAAACTAAAATAGATACATATAAACTATTATAAACATTAAAACACATTATAAACATATACATTTATAAATTTATAAATTATAAACACATCATTTTTTCCATAAAATTGCTATAAGGTAAAAGCATAGTCAGCATGATCAAACAAACTAATAGTATTTATTTATTATTTATTTATGTAAACACTGCTGTTTTATTTTTAACCTCTTTTTAAGAACACTACTAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15240
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077627 Nonsense 760 1106 13 20
ENSDART00000139237 Nonsense 742 1046 12 18
Genomic Location (Zv9):
Chromosome 13 (position 25814990)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 25460650
GRCz11 13 25591100
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAATKACTYTAACCATTMATTTTTTCACCACAGAAAATGCRTCTCACAGC[G/T]AGCTTCGAGAYCTCCTSTCAGAGTTCACATTGCTYAAGCAGGTTAATCAC
Long Flanking Sequence:
TAGAGTCAACTCATTGTCATGTTCAAGAAACCAGTCTGAAGTAATTCGCGCTTTATGACATGACGTGTAATCCTGCTGGAAATAACCATCAGAAGATGGGTACAATGTGGTCATAAGGGGATTGACATGATCAGCAACAATTCTTAGGTAGGCTGTGGCATTGACACAATGATCAATTGGTACTAATGGGCCCAAAGTGTGCTAAGAAAATATCCCCCACACCATTTCACCACCTCCACTTGCCTGAATCATTGATACAAGGCAGGATGGATCCACACTTTCATGCCTAAATGCATCAAGTTTCTGCCATGTGATTGACTGAGTAGATATTTGCATTAATGAGCAATTGGACAGGTGTACCTAATAAAGTGGCCGGTTAGTGTATGTCATTTGCATATGTTGCCATCAGATTTCTGTGTGGGATGCATTTGATCAAATCACTTTAGTCTGAAATTACTCTAACCATTCATTTTTTCACCACAGAAAATGCATCTCACAGC[G/T]AGCTTCGAGACCTCCTCTCAGAGTTCACATTGCTTAAGCAGGTTAATCACCCTCATGTCATTAAAATGTATGGAGCTTGCAGCCAGGATGGTAAGATGTTATACACAAACACCTGTATGTTCATTTCATGCATTTGTTTCCACTTTGCTGTGTGTGCTTACTTATGTTAATGTGTTCAGGTCCATTATACTTAATTGTTGAATACGCCAAGTATGGTTCACTACGTAACTTCCTGAGAGAGAGCCGCAAAGTTGGGCCAAGCTATATGGGCAATGATGCCAACCGCAACTCCAGCTACTTGGAAAACCCAGACGAGAGAGCTCTGACCATGGGCGACCTGATCTCGTTCGCCTGGCAGATCTCTAGAGGAATGCAATACCTAGCTGAGATGAAGGTATGCCAGTGATTTGAGGAAAATATACAACACCGAATACCTGATGTTCTATTTTTAAAGAAAATTTATAAAGGGAAAATTTGTATTAAGCTTGTTCACAGAGACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22307
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077627 Nonsense 800 1106 14 20
ENSDART00000139237 Nonsense 782 1046 13 18
Genomic Location (Zv9):
Chromosome 13 (position 25814781)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 25460441
GRCz11 13 25590891
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACTTATGTTAATGTGTTCAGGTCCATTATACTTAATTGTTGAATACGCC[A/T]AGTATGGTTCACTACGTAACTTCCTGAGAGAGAGCCGCAAAGTTGGGCCA
Long Flanking Sequence:
ATATCCCCCACACCATTTCACCACCTCCACTTGCCTGAATCATTGATACAAGGCAGGATGGATCCACACTTTCATGCCTAAATGCATCAAGTTTCTGCCATGTGATTGACTGAGTAGATATTTGCATTAATGAGCAATTGGACAGGTGTACCTAATAAAGTGGCCGGTTAGTGTATGTCATTTGCATATGTTGCCATCAGATTTCTGTGTGGGATGCATTTGATCAAATCACTTTAGTCTGAAATTACTCTAACCATTCATTTTTTCACCACAGAAAATGCATCTCACAGCGAGCTTCGAGACCTCCTCTCAGAGTTCACATTGCTTAAGCAGGTTAATCACCCTCATGTCATTAAAATGTATGGAGCTTGCAGCCAGGATGGTAAGATGTTATACACAAACACCTGTATGTTCATTTCATGCATTTGTTTCCACTTTGCTGTGTGTGCTTACTTATGTTAATGTGTTCAGGTCCATTATACTTAATTGTTGAATACGCC[A/T]AGTATGGTTCACTACGTAACTTCCTGAGAGAGAGCCGCAAAGTTGGGCCAAGCTATATGGGCAATGATGCCAACCGCAACTCCAGCTACTTGGAAAACCCAGACGAGAGAGCTCTGACCATGGGCGACCTGATCTCGTTCGCCTGGCAGATCTCTAGAGGAATGCAATACCTAGCTGAGATGAAGGTATGCCAGTGATTTGAGGAAAATATACAACACCGAATACCTGATGTTCTATTTTTAAAGAAAATTTATAAAGGGAAAATTTGTATTAAGCTTGTTCACAGAGACCTGGCTGCAAGGAATGTGCTGGTGGCAGAAGGAAGGAAGATGAAAATATCAGACTTTGGTTTGTCTCGAGATGTCTATGAGGAAGATTCATACGTGAAGAGGAGCAAGGTGATCTATTTTGTTAAACTGCATTAAATTAGTCACACGCCCCCACCGATGTTTTAATGGGTCTAATTATTCCTTTAGTTTGTAATGTTGTTATTTGTACGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2684
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077627 Nonsense 849 1106 14 20
ENSDART00000139237 Nonsense 831 1046 13 18
Genomic Location (Zv9):
Chromosome 13 (position 25814634)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 25460294
GRCz11 13 25590744
KASP Assay ID:
554-2592.1 (used for ordering genotyping assays)
KASP Sequence:
ACCCAGACGAGAGAGCTCTGACCATGGGCGACCTGATCTCGTTCGCCTGG[C/T]AGATCTCTAGAGGAATGCAATACCTAGCTGAGATGAAGGTATGCCAGTGA
Long Flanking Sequence:
GTACCTAATAAAGTGGCCGGTTAGTGTATGTCATTTGCATATGTTGCCATCAGATTTCTGTGTGGGATGCATTTGATCAAATCACTTTAGTCTGAAATTACTCTAACCATTCATTTTTTCACCACAGAAAATGCATCTCACAGCGAGCTTCGAGACCTCCTCTCAGAGTTCACATTGCTTAAGCAGGTTAATCACCCTCATGTCATTAAAATGTATGGAGCTTGCAGCCAGGATGGTAAGATGTTATACACAAACACCTGTATGTTCATTTCATGCATTTGTTTCCACTTTGCTGTGTGTGCTTACTTATGTTAATGTGTTCAGGTCCATTATACTTAATTGTTGAATACGCCAAGTATGGTTCACTACGTAACTTCCTGAGAGAGAGCCGCAAAGTTGGGCCAAGCTATATGGGCAATGATGCCAACCGCAACTCCAGCTACTTGGAAAACCCAGACGAGAGAGCTCTGACCATGGGCGACCTGATCTCGTTCGCCTGG[C/T]AGATCTCTAGAGGAATGCAATACCTAGCTGAGATGAAGGTATGCCAGTGATTTGAGGAAAATATACAACACCGAATACCTGATGTTCTATTTTTAAAGAAAATTTATAAAGGGAAAATTTGTATTAAGCTTGTTCACAGAGACCTGGCTGCAAGGAATGTGCTGGTGGCAGAAGGAAGGAAGATGAAAATATCAGACTTTGGTTTGTCTCGAGATGTCTATGAGGAAGATTCATACGTGAAGAGGAGCAAGGTGATCTATTTTGTTAAACTGCATTAAATTAGTCACACGCCCCCACCGATGTTTTAATGGGTCTAATTATTCCTTTAGTTTGTAATGTTGTTATTTGTACGGTGGCTGATAGAGGTCAAATGTTCTGCAAGAAAAGAAAGCACAATCCAATGAACAAAAAATTATGAACAAATTATGCAAATTATACAAATAATGAAAACCTCTTCATCAGTTTGACAACACACTTAAAATAAATTCTCACAACACATG
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461