ZMP

CHRNA4 (3 of 3)

Ensembl ID:

ENSDARG00000087071

Description:

cholinergic receptor, nicotinic, alpha 4 [Source:HGNC Symbol;Acc:1958]

Human Orthologue:

CHRNA4

Human Description:

cholinergic receptor, nicotinic, alpha 4 [Source:HGNC Symbol;Acc:1958]

Mouse Orthologue:

Chrna4

Mouse Description:

cholinergic receptor, nicotinic, alpha polypeptide 4 Gene [Source:MGI Symbol;Acc:MGI:87888]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa45269	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa15204	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa45269

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000127176	Essential Splice Site	64	551	2	8

Genomic Location (Zv9):

Chromosome 6 (position 58411395)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	6	58514523
GRCz11	6	58508754

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGTGGTTCACGTTCACTTCGGTCTGTCCATCGCTCAGCTCATCGACGTGG[T/A]ATAATCCGCAAACACCTTCTGAAGAGATTGCAAATCCCAACACCATCATT

Long Flanking Sequence:

ACATTGCAATGTTGTGCATCTGAGCTTGTCGCTGAAACCGTAAACACTTTGCTTTTTCATTGTTTTGATGGATTTACGAACATTTCAGCCATCGATGGAGAAACTGGAGTGAAGAAAAGGTGCTTTTGAAAGTTTTCAGGACCAAAACAACAGTGATAAACAGATCCAGGACGCCATCTTCATCATGTTTTTCTGTCTTCATCTTCTGCTGCTTCTTTATCCGGCTCAAGGTAAAACACAGCAGGAATGCCAATGCAGGCTATAGACAGTATCATTAACCTGGACAATGGAAGTCTACAGTATATAATGTCCTCATTAAGATAGTGAAACAAACCTGTGTGTGTGTGTGTGTTTAGTGTGCTGTGATGAAGTCCAGGCTGAAGAGCGTCTGCTGAACTCTCTGCTCTCAGCATACAGTAAACTGACCCGTCCGGTTCACAGTGTCTCTGATGTGGTTCACGTTCACTTCGGTCTGTCCATCGCTCAGCTCATCGACGTGG[T/A]ATAATCCGCAAACACCTTCTGAAGAGATTGCAAATCCCAACACCATCATTTATTACAGCCTAGGCTCAGTGTAAATAAATGCCTGAGCCTGCATTATTGCAGAACATTAAAGACGCTACTTGGGGTGTGTTGCATGACACGTTTCAGATGACAAATCCAGTAGAGGGCGCTGTCTACATTTTTGCAAATCTGATATACGTGTATTTTGTTGCATAGCTTTAAGTATGTTTTTGAGAATTTTCAAAACGTTAGACAAAGGTAGACTAATGGTACAGCATGTTTAACAGATTACCAAACCAACCGTTATTGTGATAAACTATAAAACTCTATCTTATATCTTCACCAGGATGAGAAAAATCAAATGATGACCACTAATGTGTGGGTGAAGCAGGTGAGTGTTAAACTCTGCGGACCCGGTCCGTGACGTCATCGACTTTCGCTTTCAGATTTATAGGGCTAGCGTTGCACCAGGCCCCCGTAAGTGGTGTCGTTAGAAAGTG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa15204

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > G

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000127176	Nonsense	145	551	7	8

Genomic Location (Zv9):

Chromosome 6 (position 58419170)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	6	58522298
GRCz11	6	58516529

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GCTCACCTTTTMCATGACGGAAGAGTAANNNNNNNNCCTCCGGCCATCTA[T/G]AAAAGCTCCWGCAGCATYGRYGTCACCTTCYTCCCCTTCGACCAGCAGAA

Long Flanking Sequence:

GAGCCCATACAATATATCTGATCTAAATTTTTTGTAAAACAATAGCTTTGTGTTGAGGCAATCGTGTGAGAAGCATCTTTCTCCACTGATTCAGGGTGCTGCAAATCATTAAAAATACTTTAATGTTTTCAAGGTTTTGAAAGTGCTTAGATTTTGAATAAAGGGCTATACTGTAGAATATATCAAATAGCATCTGACATAATGTGAAGTTATGTAAGTGTGTAACTTGCCACACTTGTAAAGTGCTAGAAAGTTTTGAAGATGAATCTGAAAAGTGCTTGAAATGTACTTAAATTTGATTATGTAAGAACCTTTTAAGAAGCTCTGTACACTTATAAAACAATTTATTTGCCTCAAAATGTTATTTCACACAATCAGAAGTAAGACTAAAGAGCAACACTGTGTTTCTGCAGTGCAGATGGTGATTTCACAGTGACGCACCTGACTAAAGCTCACCTTTTACATGACGGAAGAGTAACCTGGATCCCTCCGGCCATCTA[T/G]AAAAGCTCCTGCAGCATCGATGTCACCTTCCTCCCCTTCGACCAGCAGAACTGCACCATAAAGTTCGGCTCCTGGACGTACGACCGCAGCAAAATCGATCTGATCCGCATTGCAGACAGTGTAGACCAGCTGGACTACTGGGAGAGCGGAGAATGGCTCATAACCAGCGCTGTCGCCACATATAATGTGAAGAAATACGAATGCTGCTCTGAGGAATATGCAGACATCACTTATTCCTTCATTATCAGACGACTGCCGCTCTTCTACACCATCAATCTCATCATCCCATGTCTACTTATTTTATGTCTAACTGTATTGGTTTTCTACCTCCCGTCTGATTGCGGAGAAGAAGTCACCATGTGCATATCTGTGCTGCTTTCACTCACAGTCTTCCTCTTGCTGATCACAGAAATCATCCCGCCGACCTCATTGGTGATTCCTCTGATTGCAGAATACCTGCTTTTCATCATGATTTTCATCATACTTTTCATAATAATCAC

Associated Phenotype:

Not determined