Busch Lab

ZMP

cnot1

Ensembl ID:
ENSDARG00000004174
ZFIN ID:
ZDB-GENE-040915-1
Description:
CCR4-NOT transcription complex subunit 1 [Source:UniProtKB/Swiss-Prot;Acc:A1A5H6]
Human Orthologue:
CNOT1
Human Description:
CCR4-NOT transcription complex, subunit 1 [Source:HGNC Symbol;Acc:7877]
Mouse Orthologues:
CT025624.1, Cnot1
Mouse Descriptions:
CCR4-NOT transcription complex subunit 1 [Source:UniProtKB/Swiss-Prot;Acc:Q6ZQ08]
CCR4-NOT transcription complex, subunit 1 Gene [Source:MGI Symbol;Acc:MGI:2442402]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa14563 Nonsense Available for shipment Available now
sa44264 Nonsense Mutation detected in F1 DNA Not yet available
sa15191 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa14563
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017536 Nonsense 399 2375 11 49
ENSDART00000125459 Nonsense 399 2374 11 49
ENSDART00000141311 None None 293 None 7

The following transcripts of ENSDARG00000004174 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 25 (position 17689614)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 17236455
GRCz11 25 17332855
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGGGGTCTGGGAATGGAAGTGTTCCCGGTGGATCTCATTTACAGACCATG[G/A]AAGCATGCAGAAGGACAGGTAAATAATGCACCACTCAGTTTTAAAATAAT
Long Flanking Sequence:
CAATCCAGTGGGCGGTGGTGGGATCTGGAGTGACGGGAAGGACAAAAGTGACAGCTCTCAGGCCTGGAATGTTGAAGTTCTAATTGATGTGGTCAAAGAAGTGGTAAGTTTCTGGTTATTTTGAGGAGCTTTCATGTTTAGTTTGTTTCTGAAGCTAAAACATTTTCTCAGTTTAGTTAGTTTAGAAATGCGAGGTATGCAAAGCAGCAGTGATCGTTTTGCTAATTCCTTTCAAAAGGAATTTTAAATTGTGGATTGACCTGGTCGCGCAAACAAAGCTGATGATGAACAAACATATTTCAGGACTTTTTCATTTTAGCTATGTCTGACGCTACTTATTCCCTTTAGAACCCTAATCTGAATTTCAAAGAGGTGACCTATGAGCTGGATCACCCAGGCTTCCTGATCCGGGACAGTAAGGGGCTTCAGATAGTTGTTTATGGGATCCAGAGGGGTCTGGGAATGGAAGTGTTCCCGGTGGATCTCATTTACAGACCATG[G/A]AAGCATGCAGAAGGACAGGTAAATAATGCACCACTCAGTTTTAAAATAATCAAATCAATTGTATGAATTTTTTAACTTTGCAGTGAAAATGAAGTAGCTTATTTACATTTGGCTGTAATTAGTTTTGTGTTTTATTTTCAGTTGTCGTTCATTCAGCACTCTCTATTGAGTCCTGAAGTGTTCTGCTTTGCTGACTACCCTTGCCATACTGTTGCTATTGACATCTTGAAGGCTCCACCTGAGGATGACAACAGGGAGATAGCCACATGGTAAGTCTCAAACCAATTAATGTTACATCTAATCTTTACAAAAATGCTCAGTCATGAATGGTTTTTATACCTCCTTCCATTTTGGTCAACAGGAAGAGCTTGGACCTTGTAGAGAGCCTCTTGCGCCTCTCTGAAGTTGGGCATTATGAACAGGTGAAGCAGCTTTTTAGCTTCCCCATCAAACACTGCCCGGACATGCTGGTGTTGGCGCTCCTGCAGATCAGTACCTCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44264
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017536 Nonsense 677 2375 17 49
ENSDART00000125459 Nonsense 677 2374 17 49
ENSDART00000141311 None None 293 None 7

The following transcripts of ENSDARG00000004174 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 25 (position 17693383)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 17240224
GRCz11 25 17336624
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGTGTCTCAAGAGCTGTCAGAGACAATCTTGACCATGGTGGCCAACTG[T/A]AGCAATGTGATGAACAAGGCTCGGCAGCCGCCACCAGGAGTCCTGCCAAA
Long Flanking Sequence:
ACAACGTGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGTTCTTGTCATTTTTCTCATGATGTATGTAATTATGCAACGCTTGTCACTGCTTAGAATGCTTTTGTGAAATATGTTTATTGTATTCTGTGTAAGAAGATGCATCATTTCAGAAAAGCACTTATTTACTTTAAAGATGACTGCGCACAACAATCATATGTCATTTATTGTTCAACATTTATTGTGTGGTGTGTCATAGTAATCAACAATTAATATCTGTGGTGCTTCGCGTTGTCCTAAGGAGCACAGAGAGTCCTGCAACACAAGAATTGAGTTTAAATTGCATAATTGAACATGGTGACTATCATAACTGACAGAACACAGCATTAAGCATGTACACATTAAAAAAGTGCTTGGGTTGAGGTTGAACTTTTTTATTTTTATTTTGAGCAGGAGTGTGTCTCAAGAGCTGTCAGAGACAATCTTGACCATGGTGGCCAACTG[T/A]AGCAATGTGATGAACAAGGCTCGGCAGCCGCCACCAGGAGTCCTGCCAAAGGGACGAGCGCCCAGCACCAGCAGTTTAGATGCTATCTCACCTGTGCAGGTAACCATGCCTGTACCAACTGATTGAATATCGATATCAGTGTCAAGATTCCCTGATGGTGGTGTTCTCAAATCTGTCCTGTTGTATTCCAGATGGACCCTCTCTCTGCAATGGGCTCTTTAAGTCTAGGTGTCTCGTCCACCTCTCACACCCCGAGCATGCAAGGATTCCCCAGCCTGCAGGGCTCTGCCTTCAGTAACCCCCAGTCCCCAGCCAAAGCCTTCTCAAACCTGCCCAACCCAAACCCCAGCACAGCTTTCCCTGGAATCAACCCCCTCTCTTCACAGCTCCAAGGTACCATAAGAGCGCTGTGTATTAATGAACTCTGATTCCAATCATAATGAGGCTGTGTGTTATTGGAATTGAACACATTACTTGAATTGCTTCCTTAGGTCCTCTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15191
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000017536 Essential Splice Site 1269 2375 29 49
ENSDART00000125459 Essential Splice Site 1269 2374 29 49
ENSDART00000141311 Essential Splice Site 36 293 3 7

The following transcripts of ENSDARG00000004174 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 25 (position 17696838)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 17243679
GRCz11 25 17340079
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CARGTTTTTGAWGAAYGGTTTTCACTCAGTCCCACWATTCTGTYGTTGCA[G/T]CTTAACCTCAAATTTGAGATTGAGGTACTCTGCAAGAATCTGTCTATGGA
Long Flanking Sequence:
GAAGAATTTGGGTCACTGGCTTGGAATGATCACCCTAGCAAAAAACAAACCCATCCTGTATACAGTGAGTTCATTTATTATTCATCACCTTTGTAAAATGTGTAGAGCATGTGTTGTTTTACCAGCATTAATGTACTGTGCTCATATAGGACCTGGAGCTGAAATCTCTTTTGTTGGAGGCTTATGTGAAAGGCCAGCAGGAGTTACTGTATGTCGTCCCTTTTGTGGCCAAAGTCTTGGAATCAAGTCTGCGGAGTGTGGTAATAATGAGTTCTGATAATCATGACATATTTTTTTATATCAGAACATAAATTAATTGGTGCTGTGTTTTGTAGATCTTCAGACCGCAGAACCCTTGGACAATGGGCATCATGAATGTACTGGCTGAACTCCACCAGGAGCATGACCTAAAGGTCAGTAACCTCTCTTTGACGCTAAATGTATAGTGCACAGGTTTTTGATGAATGGTTTTCACTCAGTCCCACAATTCTGTCGTTGCA[G/T]CTTAACCTCAAATTTGAGATTGAGGTACTCTGCAAGAATCTGTCTATGGACATCACTGATCTTAAGCCAGGGAACCTGCTGAGAGACAAAGATAAGCTGAAGACCTTGGAGGAGCAGCTCTCCGCACCAAAGAAAGAGACCAAGCCTCCTGAAGAATTGCTGCCTATAGTTACAACAGGTATTACACTAAACTGGACACATTGTAAATGACATGCTGTTTGCCATATTTTCCAGTTCTGGTTTAACCAGAAGCAGACTCTGTTCCTTTCACAGCTGCTCCCTCAACTCCGGCCACCACCACGGCCTGTACAGCCACTGGGCCACCTACACCTCAGTTCAGCTATCATGACATCAATGTGTATGCATTGGCTGGACTGGCCCCACACATAAACATCAATGTTAACGTTAGTTACTCACTCTACCAACCAATTCATTACCCCTTTTCAAATAGCGTTAATTAAGACACTAACAATTTTTACCTTAACGTTTATAGATCCCAC
Associated Phenotype:
Not determined