Busch Lab

ZMP

lhx1a

Ensembl ID:
ENSDARG00000014018
ZFIN ID:
ZDB-GENE-980526-347
Description:
LIM/homeobox protein Lhx1 [Source:UniProtKB/Swiss-Prot;Acc:Q90476]
Human Orthologue:
LHX1
Human Description:
LIM homeobox 1 [Source:HGNC Symbol;Acc:6593]
Mouse Orthologue:
Lhx1
Mouse Description:
LIM homeobox protein 1 Gene [Source:MGI Symbol;Acc:MGI:99783]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa15189 Nonsense Available for shipment Available now
sa42561 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa15800 Nonsense Available for shipment Available now
sa39051 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa15189
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005641 Nonsense 22 405 1 5
ENSDART00000134373 Nonsense 22 97 2 3
Genomic Location (Zv9):
Chromosome 15 (position 27059150)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 27777390
GRCz11 15 27710266
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGGGCTGCGAGAGGCCTATATTGGACAGGTTTCTCCTTAATGTTCTGGAC[A/T]GAGCATGGCACAKCAAGTGCGTACAGTGCTGCGAGTGCAAATGTAACCTA
Long Flanking Sequence:
ACTTTAATGCACATCCTCACCAATGCTTCACCTTGTTGACAACGACGACGTGCTTTTCACGCAATGATGTGCTTACCTTTGTAGCCAACGAACAGTTGGTGTTTTGAAAGATTTCTCTATGCTGGCTTCATTTATGCACCTCAAAATTTGGGACGGAAGAGGACGAGAAATGATGACTGACTACTGAAGCACTACCTCATGAGAAAATCTTCTATCGTCTTCATTTTGGACCCCTACAGGTCCACCCACAAACGCAGAACTGGTGAATATATTTAAAACTTCTTCATCTTTTCGTTTCAACCCTGTTCGCAAAGACTGACTTGGAACATCCTTCAGCGATACAACTTTTCCTCCTCTCTTTTAAAAGAGAGAAATCAGGAGCAGAGCCTCAGGTTGTGGACACCACGGCAGTAACTGTGGGAGCACATCCAAAGACGATGGTCCACTGTGCGGGCTGCGAGAGGCCTATATTGGACAGGTTTCTCCTTAATGTTCTGGAC[A/T]GAGCATGGCACATCAAGTGCGTACAGTGCTGCGAGTGCAAATGTAACCTAACAGAGAAATGCTTCTCTCGAGAAGGAAAACTATATTGCAAAAACGACTTCTTTAGGTAAGTTCCTTGCGTGAGTTAATTCGACCAAATATTTTACTTGTGGGGTTTTTGTGATAAATGGATAATTAATCGTTTATAAAGTAGCTATTATGTAGGCCCACTTCAGAAAATCTAGTACAGATGTCTACCATAATAATACAAATATTCTACGAACAAGATGAATATATTACCCGTTGTTGTGTATCTATGGTATATCTATGAAACATTTCTATATAAAATATATAATGTATCGTTAATATATGACAGAAATAAATCCAGAAGACACCCAAAATTATTTCATTTTAAAATTACACATTTACATTTTAAAGAGGTTCCACAATTGAGCTTAAAACAACATCACTTTAAAAGGTGAAATCACATTTTTTAAAGTCACTCAAAAATAACTAAATTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42561
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005641 Essential Splice Site 57 405 None 5
ENSDART00000134373 Essential Splice Site 57 97 None 3
Genomic Location (Zv9):
Chromosome 15 (position 27059042)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 27777282
GRCz11 15 27710158
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATGCTTCTCTCGAGAAGGAAAACTATATTGCAAAAACGACTTCTTTAGG[T/A]AAGTTCCTTGCGTGAGTTAATTCGACCAAATATTTTACTTGTGGGGTTTT
Long Flanking Sequence:
AGATTTCTCTATGCTGGCTTCATTTATGCACCTCAAAATTTGGGACGGAAGAGGACGAGAAATGATGACTGACTACTGAAGCACTACCTCATGAGAAAATCTTCTATCGTCTTCATTTTGGACCCCTACAGGTCCACCCACAAACGCAGAACTGGTGAATATATTTAAAACTTCTTCATCTTTTCGTTTCAACCCTGTTCGCAAAGACTGACTTGGAACATCCTTCAGCGATACAACTTTTCCTCCTCTCTTTTAAAAGAGAGAAATCAGGAGCAGAGCCTCAGGTTGTGGACACCACGGCAGTAACTGTGGGAGCACATCCAAAGACGATGGTCCACTGTGCGGGCTGCGAGAGGCCTATATTGGACAGGTTTCTCCTTAATGTTCTGGACAGAGCATGGCACATCAAGTGCGTACAGTGCTGCGAGTGCAAATGTAACCTAACAGAGAAATGCTTCTCTCGAGAAGGAAAACTATATTGCAAAAACGACTTCTTTAGG[T/A]AAGTTCCTTGCGTGAGTTAATTCGACCAAATATTTTACTTGTGGGGTTTTTGTGATAAATGGATAATTAATCGTTTATAAAGTAGCTATTATGTAGGCCCACTTCAGAAAATCTAGTACAGATGTCTACCATAATAATACAAATATTCTACGAACAAGATGAATATATTACCCGTTGTTGTGTATCTATGGTATATCTATGAAACATTTCTATATAAAATATATAATGTATCGTTAATATATGACAGAAATAAATCCAGAAGACACCCAAAATTATTTCATTTTAAAATTACACATTTACATTTTAAAGAGGTTCCACAATTGAGCTTAAAACAACATCACTTTAAAAGGTGAAATCACATTTTTTAAAGTCACTCAAAAATAACTAAATTGGAAGAAATTTCTCCAGCGATTCAACAGCTTTACACAGAGCTTTGCATGATTTTATTAGATTTAGGACTTACATTCACACTAACAAGAAGTGTGATCCTAAGTACTGTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15800
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005641 Nonsense 114 405 2 5
ENSDART00000134373 None None 97 None 3
Genomic Location (Zv9):
Chromosome 15 (position 27057573)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 27775813
GRCz11 15 27708689
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTTCCACAGGAGAGGAATTGTACATCATAGAYGAAAATAAATTTGWCTG[T/A]AAAGAYGATTATTTAAGCAACACGAAYGGAAAAGACTCAAATCTCCTATC
Long Flanking Sequence:
TTTAATGCACATTACTAACCTGCTCAATAAACGTATATGTTTTTTTAGGCCTACAGTGGAAAAAAAGTACATGCTAATGCATATATAAATATTATTTTGTTTGCGTATTCTAAAATGCTGTAACCAATAACAATTAACCAGGTAAATATTTTTCCCAAAAAATAACTTTGATGGTAATACTTAACATTTAGGAGCATTCGAATTTTATATGAACTCAAATAAGTGATGCTATTCAATAAGTCTCGCCTGAGCTTATGCAGATAATTTCGTATTTTTCTTTCGTTTTACTCCTGTATATTGACCTTTTTTTTGGTCTGTCCATTTTGCAGGCGCTTTGGAACAAAATGTGCGGGTTGTGCTCAGGGGATCTCGCCGAATGACTTGGTCCGGAGGGCACGGAGCAAAGTGTTTCATCTGAACTGCTTCACATGCATGATGTGTAACAAGCAGCTTTCCACAGGAGAGGAATTGTACATCATAGACGAAAATAAATTTGTCTG[T/A]AAAGACGATTATTTAAGCAACACGAACGGAAAAGACTCAAATCTCCTATCAGGTAAGTAAATGATGCTAGAATTGAAAATATGTATTGCATGCTGCAAGCGGGTTTATTTCCCCCCACATATTTTTTGCTTTTTGATTAAATGTTTATTAGCAATTCATATTTTGTTGTAAAACATTTTTTAAACAATAAAGACAAATATTGTTCAGAATAGGGCTGTAGATTGAAATGTTTTGTTTTCTTAAACAGTACACTAAAATAGATCTTCAGATGGGGCACGACAATCTAAACAAGCTTGTTTAGAATTTTCTCTACCAATTTCCATGTCAAATGAATTGCATTAAATTAGTAGCCTATCGCGATGTTGGTCAGTTTATTTACTAATAATAATTTCACTGTCGTAGACTAGTGCATCGTGACAGTTCTTTCAACTGTAAATACCATTATTTCTTTGTTCCTTGTTTGTAGATTAATTTCTTTTTTTATTCTTTCGAAATTTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39051
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005641 Nonsense 147 405 3 5
ENSDART00000134373 None None 97 None 3
Genomic Location (Zv9):
Chromosome 15 (position 27056885)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 27775125
GRCz11 15 27708001
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTCAGTTACAGCTTGCAGTGATCCTAGTTTATCGCCAGATTCTCAAGAC[C/T]AGCTACAGGACGATGTCAAGGATGCGGAAATCGCAAATTTATCGGACAAA
Long Flanking Sequence:
TAAAGACAAATATTGTTCAGAATAGGGCTGTAGATTGAAATGTTTTGTTTTCTTAAACAGTACACTAAAATAGATCTTCAGATGGGGCACGACAATCTAAACAAGCTTGTTTAGAATTTTCTCTACCAATTTCCATGTCAAATGAATTGCATTAAATTAGTAGCCTATCGCGATGTTGGTCAGTTTATTTACTAATAATAATTTCACTGTCGTAGACTAGTGCATCGTGACAGTTCTTTCAACTGTAAATACCATTATTTCTTTGTTCCTTGTTTGTAGATTAATTTCTTTTTTTATTCTTTCGAAATTTGTTTTTGTGCTTTATTTATAGTGTTTATTTATTTATTTATTTTACATTCCAGTGTTTAGTGTTCAGCGCATCTCAGGTCACCATGTCTAATTCAGATTTTTTTTTTCGACTCCCTTTTTTTCCGACGGCCCCTTTTCCCTATTCAGTTACAGCTTGCAGTGATCCTAGTTTATCGCCAGATTCTCAAGAC[C/T]AGCTACAGGACGATGTCAAGGATGCGGAAATCGCAAATTTATCGGACAAAGAAACGGGTAACAATGAAAATGATGACCAGAACCTTGGAGGCAAACGGAGAGGACCGCGTACCACTATTAAAGCAAAGCAACTGGAGACACTGAAAGCGGCATTCGCGGCGACCCCCAAACCAACCAGACACATCAGGGAGCAACTGGCGCAAGAGACGGGACTCAACATGCGAGTTATTCAGGTAAAATTGCACATTATTGCATAAATTTGATGTGTGTGTTATTAATTACATTATTGCTTTGGTCCTAACAATTGCAAGGATCAAAACGCTAAAACATGAATGTCGATATTGATATTTGAAGAATAATATAGCTTATAGCATGCGATTCTTAAGCATCTTGTGGTATAAATTTCTCTCTTTGGATGAAATTGTGAAAAGCACACGCGCGCCTTCTTTGTGCTTCTCATTGCCAATCCTTGAGGCAAGACTATTTGAATTAAAATGAGG
Associated Phenotype:
Not determined