Busch Lab

ZMP

appbp2

Ensembl ID:
ENSDARG00000007566
ZFIN ID:
ZDB-GENE-030131-1715
Description:
amyloid protein-binding protein 2 [Source:RefSeq peptide;Acc:NP_997798]
Human Orthologue:
APPBP2
Human Description:
amyloid beta precursor protein (cytoplasmic tail) binding protein 2 [Source:HGNC Symbol;Acc:622]
Mouse Orthologue:
Appbp2
Mouse Description:
amyloid beta precursor protein (cytoplasmic tail) binding protein 2 Gene [Source:MGI Symbol;Acc:MGI:

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa4606 Nonsense F2 line generated Not yet available
sa1303 Essential Splice Site Available for shipment Available now
sa16354 Nonsense Available for shipment Available now
sa15168 Nonsense Available for shipment Available now
sa13157 Essential Splice Site Available for shipment Available now
sa22644 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa4606
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002824 Nonsense 45 446 1 11
ENSDART00000110234 Nonsense 45 586 1 14
ENSDART00000137569 None None 246 None 6
Genomic Location (Zv9):
Chromosome 15 (position 23296064)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 24007251
GRCz11 15 23942516
KASP Assay ID:
554-3526.1 (used for ordering genotyping assays)
KASP Sequence:
CGACGGGACATCCGATCTCTCCCCGAAAATATACAGTTTGATGTGTACTA[C/A]AAGGTAAGAAGCACGATGATGGAGTTYAGGGCGGAACAGCCGTCAAAATC
Long Flanking Sequence:
ACAGTCAGAAAGGTTCTGTCACAAACCTTTAATCACTTCTGAGAGATTTCTTCTGTCCTCCCAGCGGCAGTTGTTTTGAACTGCAATCAAATGCGCGTTCACTGAGTGCAAGCGCTACGTCATTGCCTAAAGTGTCATAGAGTGGGCGGGGCATCTCGATCGGGGATGAGCTTTAAACATGAGAGCATAACCAGGGGGTTGTGTTCTCTATCATAACAGCCCATTTCAACCTCAAAAAGCGCTTCCAGCCGCGGGGGTGTATGAGGAACACCAGAGTAAAGCGTTTTACCTCGATCAGGTAGCGAAGGAGGTGAAAGTAGGAGTGGAAGAGGGGGGCTGTGGTTGGATTTAGTGAAAGAAAACAATATGGCCGCGGTGGAGCTGGAATGGATCCCTGAGACCCTTTACAACACTGCTATTTCAGCCGTGGTCGACAACTACGACCAGTCGCGACGGGACATCCGATCTCTCCCCGAAAATATACAGTTTGATGTGTACTA[C/A]AAGGTAAGAAGCACGATGATGGAGTTCAGGGCGGAACAGCCGTCAAAATCATCTGACACTTTTTTACTAGCAGTTAGGCTAACAAAAACTGAATCAACCTCTCAGTGGAGCACTGGTTAGGAGAAATTCGAGCTACGAGACCATTTAACCTGGTTAAATCCTGGTTTACGAGTACATTCATATTTCTGTGTGGCAGTTAGACTGTTAAAACCTAAGTGCCCACTGTTTAGTTATCCTAGCTTGTAGCTTATCTACTACTGTATGAGATACAGCTCTCTGGGTCAACACTAGTTAACCATACAGTACCATGACATTTCACTTTTTACCCTTTTAACCTATTTATGATTACTAGGTCAGTGTAATATTATGGGACGTTTAACCAAACCCGTGTTTTGAACGAATTTGGCGAGTGTCATCTGTAAAAACGGTTTGTTACCAACTGCTGTGAATACAATAAATGACCACTGTAACGTTACAGTAAGATAAAAACAGCAATGCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1303
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002824 Essential Splice Site 224 446 5 11
ENSDART00000110234 Essential Splice Site 224 586 5 14
ENSDART00000137569 Essential Splice Site 193 246 4 6
Genomic Location (Zv9):
Chromosome 15 (position 23285437)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 23996624
GRCz11 15 23931889
KASP Assay ID:
554-1218.1 (used for ordering genotyping assays)
KASP Sequence:
GTATGGAGAACTGTGTGCCCTGCTTTTTGCCAAAAGCCACTATGATGAGG[T/C]GAGTCCCCTTGCAACTGTCCCAGAAGTCTGTTTGGAGAAGGCCTGTTCTA
Long Flanking Sequence:
AATTATACGTATACTGTATCACTGAGCACTGTATCATCCTCAGTTATTTTAACCATGACTGTATATCCAATAAAACGATCAAAACAATTTAAAAGCCCAATAACTAATATCATTATTATTATTATTATTATTATTTAGAATTTTACATTTACTGTGTTAATTACATAGTTTTTATGGTCATTAGATCTTGGTTGTAAAAAAGCAGAAGAGTGTGTTACTTTGATATGTATTTATATGATATTGTATTAGTTCAAAATGTTAATCAATATTTTTGTAAAAAATAAACATTTTGACATGCAAGCTAATTTTATGCTGATTCTTATGTGCCAGGTTACTTCATGTGCGTAACGGCAACTGCAAATACCACCTGGGAGAAGAGACTTTTAAACTAGCCCAGTCTTACATGGACAAACTAGCCAAACACGGACATCAGGCTAATAAGGCTGCCTTGTATGGAGAACTGTGTGCCCTGCTTTTTGCCAAAAGCCACTATGATGAGG[T/C]GAGTCCCCTTGCAACTGTCCCAGAAGTCTGTTTGGAGAAGGCCTGTTCTACATTAATGTTTTCCTTGTGCATTTCAGGCCTATAGGTGGTGTATAGAAGCTATGAAAGAGATCACAGTCGGCTTACCTGTGAAAGTAGTAGTTGATGTTCTCAGACAAGCCTCAAAGGTCTGTTATTGTTGGATGTTTGAGTTATTCAATGTTTCTAATAATGAATCTAAAAAAGTGTCTACATTGATCTCTGCAGGCTTGTGTTGTTAAGCGGGAGTTCAGGAAAGCTGAACAACTGATTAAACACGCAGTCTTCTTGGCACGGTAAGAAATATCATGTGTAGTGAGAACTATCAACTTGAAATAGTTCAGTTTGACACTTCTGAAATATGTTCACATTTTTTTCAGGGAACATTTTGGGCACAAGCATCCAAAATATTCAGATACACTACTAGATTATGGGTTTTATCTCTTAAACGTGGATAATATCTGTCAATCTGTGACCATTTA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa16354
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002824 Nonsense 287 446 8 11
ENSDART00000110234 Nonsense 287 586 8 14
ENSDART00000137569 None None 246 None 6
Genomic Location (Zv9):
Chromosome 15 (position 23285008)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 23996195
GRCz11 15 23931460
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TATGTTCACATTTTTTTCAGGGAACATTTTGGGCAYAAGCATCCAAAATA[T/A]TCAGAYACACTACTAGATTATGGGTTTTATCTCTTAAACGTGGATAATAT
Long Flanking Sequence:
TCAGGCTAATAAGGCTGCCTTGTATGGAGAACTGTGTGCCCTGCTTTTTGCCAAAAGCCACTATGATGAGGTGAGTCCCCTTGCAACTGTCCCAGAAGTCTGTTTGGAGAAGGCCTGTTCTACATTAATGTTTTCCTTGTGCATTTCAGGCCTATAGGTGGTGTATAGAAGCTATGAAAGAGATCACAGTCGGCTTACCTGTGAAAGTAGTAGTTGATGTTCTCAGACAAGCCTCAAAGGTCTGTTATTGTTGGATGTTTGAGTTATTCAATGTTTCTAATAATGAATCTAAAAAAGTGTCTACATTGATCTCTGCAGGCTTGTGTTGTTAAGCGGGAGTTCAGGAAAGCTGAACAACTGATTAAACACGCAGTCTTCTTGGCACGGTAAGAAATATCATGTGTAGTGAGAACTATCAACTTGAAATAGTTCAGTTTGACACTTCTGAAATATGTTCACATTTTTTTCAGGGAACATTTTGGGCACAAGCATCCAAAATA[T/A]TCAGATACACTACTAGATTATGGGTTTTATCTCTTAAACGTGGATAATATCTGTCAATCTGTGACCATTTACCAGGTGAGAAAATAATCGCTTTAAATGTGGGTGTGTAAATAAGCCACTTTCTCATTTGTTTGAAAGACTAAAGGCATTTCATTTGTTATTCAGACTGCATTAGATATTCGGCAGTCAGTGTTTGGAGGAAAGAATATTCATGTTGCGACTGCGCATGAAGACCTGGCGTATTCATCTTACGTCCATCAGTACAGCTCTGGTAAATTCGACACAGCACTGTGAGTATATCATTTCTGTCTAGAGAATTATGAACTAATATTCAGCACATATGCTTGGATGTTTTTTAATGCAATCTCAGAGCAGTTAATAACCTTTTAATTTACTGGCAATTGGTATAACATTTAATACTAAATTACATTTTAGTACATTATGCTCATCCTCCAATGAGAGGCGTGGTTTGGGGTAGGCCTGTCACAATAAGGAATTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15168
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002824 Nonsense 306 446 8 11
ENSDART00000110234 Nonsense 306 586 8 14
ENSDART00000137569 None None 246 None 6
Genomic Location (Zv9):
Chromosome 15 (position 23284953)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 23996140
GRCz11 15 23931405
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AYACACTACTAGATTATGGGTTTTATCTCTTAAACGTGGATAATATCTGT[C/T]AATCTGTGACCATTTACCAGGTGAGAAAATAATCGMTTTAWATGTGGGTG
Long Flanking Sequence:
AGCCACTATGATGAGGTGAGTCCCCTTGCAACTGTCCCAGAAGTCTGTTTGGAGAAGGCCTGTTCTACATTAATGTTTTCCTTGTGCATTTCAGGCCTATAGGTGGTGTATAGAAGCTATGAAAGAGATCACAGTCGGCTTACCTGTGAAAGTAGTAGTTGATGTTCTCAGACAAGCCTCAAAGGTCTGTTATTGTTGGATGTTTGAGTTATTCAATGTTTCTAATAATGAATCTAAAAAAGTGTCTACATTGATCTCTGCAGGCTTGTGTTGTTAAGCGGGAGTTCAGGAAAGCTGAACAACTGATTAAACACGCAGTCTTCTTGGCACGGTAAGAAATATCATGTGTAGTGAGAACTATCAACTTGAAATAGTTCAGTTTGACACTTCTGAAATATGTTCACATTTTTTTCAGGGAACATTTTGGGCACAAGCATCCAAAATATTCAGATACACTACTAGATTATGGGTTTTATCTCTTAAACGTGGATAATATCTGT[C/T]AATCTGTGACCATTTACCAGGTGAGAAAATAATCGCTTTAAATGTGGGTGTGTAAATAAGCCACTTTCTCATTTGTTTGAAAGACTAAAGGCATTTCATTTGTTATTCAGACTGCATTAGATATTCGGCAGTCAGTGTTTGGAGGAAAGAATATTCATGTTGCGACTGCGCATGAAGACCTGGCGTATTCATCTTACGTCCATCAGTACAGCTCTGGTAAATTCGACACAGCACTGTGAGTATATCATTTCTGTCTAGAGAATTATGAACTAATATTCAGCACATATGCTTGGATGTTTTTTAATGCAATCTCAGAGCAGTTAATAACCTTTTAATTTACTGGCAATTGGTATAACATTTAATACTAAATTACATTTTAGTACATTATGCTCATCCTCCAATGAGAGGCGTGGTTTGGGGTAGGCCTGTCACAATAAGGAATTTTTGTTGTGCGATACACAAGCGATATTATTGTCATTTTGAGATTTTATGCCACTGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13157
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002824 Essential Splice Site 313 446 9 11
ENSDART00000110234 Essential Splice Site 313 586 9 14
ENSDART00000137569 None None 246 None 6
Genomic Location (Zv9):
Chromosome 15 (position 23284843)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 23996030
GRCz11 15 23931295
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCCAMTTTCTCAWTTGTTTGAAAGACTAAAGGCATTTCATTTGTTATTCA[G/T]ACTGCATTAGATATTCGGCAGTCAGTGTTTGGAGGAAAGAATATTCATGT
Long Flanking Sequence:
TAGAAGCTATGAAAGAGATCACAGTCGGCTTACCTGTGAAAGTAGTAGTTGATGTTCTCAGACAAGCCTCAAAGGTCTGTTATTGTTGGATGTTTGAGTTATTCAATGTTTCTAATAATGAATCTAAAAAAGTGTCTACATTGATCTCTGCAGGCTTGTGTTGTTAAGCGGGAGTTCAGGAAAGCTGAACAACTGATTAAACACGCAGTCTTCTTGGCACGGTAAGAAATATCATGTGTAGTGAGAACTATCAACTTGAAATAGTTCAGTTTGACACTTCTGAAATATGTTCACATTTTTTTCAGGGAACATTTTGGGCACAAGCATCCAAAATATTCAGATACACTACTAGATTATGGGTTTTATCTCTTAAACGTGGATAATATCTGTCAATCTGTGACCATTTACCAGGTGAGAAAATAATCGCTTTAAATGTGGGTGTGTAAATAAGCCACTTTCTCATTTGTTTGAAAGACTAAAGGCATTTCATTTGTTATTCA[G/T]ACTGCATTAGATATTCGGCAGTCAGTGTTTGGAGGAAAGAATATTCATGTTGCGACTGCGCATGAAGACCTGGCGTATTCATCTTACGTCCATCAGTACAGCTCTGGTAAATTCGACACAGCACTGTGAGTATATCATTTCTGTCTAGAGAATTATGAACTAATATTCAGCACATATGCTTGGATGTTTTTTAATGCAATCTCAGAGCAGTTAATAACCTTTTAATTTACTGGCAATTGGTATAACATTTAATACTAAATTACATTTTAGTACATTATGCTCATCCTCCAATGAGAGGCGTGGTTTGGGGTAGGCCTGTCACAATAAGGAATTTTTGTTGTGCGATACACAAGCGATATTATTGTCATTTTGAGATTTTATGCCACTGATTATATAATGATTATATAACAGCATAATAATTCAAATAGCCATAAACACTTATCATGAAAATACTTATAAAGCTTAGGGTTATTTATTTAAATTCTATAATTATGGTGGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22644
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002824 None None 446 None 11
ENSDART00000110234 Nonsense 543 586 13 14
ENSDART00000137569 None None 246 None 6
Genomic Location (Zv9):
Chromosome 15 (position 23276733)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 23987920
GRCz11 15 23923185
KASP Assay ID:
2260-8481.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTTGGAAACTATGAGAAGGTATTTGAGTATCACAATATTCTGTCCAACT[G/A]GAACCGTTTAAGGGACAGGCAGTTTGCCGTAGCCGATGCGCTGGAGGACG
Long Flanking Sequence:
CTGAGGACCACAATGCAAACTTTTGGAAATGGAAATTGATATTTTTTGTATTTCAATTTTGACAGTTTTTAAAATATGTATGAGTTATTCCTATTGGCCTGTCAAATAAAAACAAACAAAACAAATATAGAGTCATTATGGTCAAAATAATTGGTCAAATTAATAAAATCAAAGATGTCAAAAAGTAAAGTAAAAAAATGGTTCATGTTTCAACTTCAGAAGTCATTCTAATTAGATTTTTTTTCTGAATGTTTAATTTAAGTTTCAAAAGAACATTTAAAAAAGTACCAAGTGTCTGTTCTGTCATTTTTAATGACTTTACCACATGTTTAAAATAGCAACCCCAGTCATTTGAATCTATCTGTTGTTTCCTTCAGGCAAGAAGCTGTTTGGGGAGGGTTACAGTGGACTGGAGTATGACTACAGAGGCCTGATAAAACTGTACAACTCAGTTGGAAACTATGAGAAGGTATTTGAGTATCACAATATTCTGTCCAACT[G/A]GAACCGTTTAAGGGACAGGCAGTTTGCCGTAGCCGATGCGCTGGAGGACGTCAACACAACCCCCCAGTCCACAGAGCAGGTGGTGCAGTCTTTCCTGCTTTCCCAGAGCCACGGAGCCGGACGCTTGGGCTAACACACCCAGCGTTCACTTTAAAAACACATAGATGTGCACAGCCACCCCCATTTCACACATTCACACCCATTTATTCACAAGTAGTCAAGGCAAGGAGGGGAAGTTTGGAGAGCTCTTGAACTGTCAGTTCACAGTTCCCATAGGCCCATTTTCCTTGAAGTGGGAACATAAACATGACCATGCTTAAACACTCACCATGGACAAGAAACCATTCTTCAAAGAACCATTGAATTATAAAAATAAAATAAAATGAAAAAGGAGCGAGGATGGAAATCTTCGAACCACCGCTTTTTTTTATTTTGTATTCGAAGGAGTGTTGCTCCACATACAGGAATACCTATCACTGCATCTGCTATTTGTGAAGAAA
Associated Phenotype:
Not determined