ZMP

HECW1 (2 of 2)

Ensembl ID:

ENSDARG00000090795

Description:

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:22195]

Human Orthologue:

HECW1

Human Description:

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:22195]

Mouse Orthologue:

Hecw1

Mouse Description:

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 Gene [Source:MGI Symbol;Acc:MGI:2444

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa15027	Essential Splice Site	Available for shipment	Available now
sa30017	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa15027

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000090301	Essential Splice Site	353	494	9	12

Genomic Location (Zv9):

Chromosome 24 (position 216070)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	179953
GRCz11	24	731727

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

AGCGGGGGGTCATGCAGCAAGCCGAAGCCCTTGTYAGGGGTTTCTATGAG[G/A]TACAAAAGCTGGAACAGTAGACGATCCACACACAGGAAGCAATTACAGTG

Long Flanking Sequence:

AGTCAACGAGGAGGTCTTCGGACAGGTGCTGGAGCTTTCACTCTGTTACTAAAGATGAGTTTTCATATGACTTTAACCAGAATTTGCTATAAATGTTAATGTGCAATGATCGGGACTGAACGATTGTAAAGGCTGAGCCTTAAAGCATCCTCAATACATACAGCAAATAAAGGCCAGATCCCATTTCTGCCCTTCAGCCCTTCCCCCTTGATTCTCTTAGACTGGGACGTTAAATTGGGATGGGTCAATAACAATTGACTTTAGCATTGCTTTGCAGATGATCAAATATTAAGATTATTATTAAGTCATAAACGTACATACAGCAGCTTTAAACGTTTGACGTCTTTTACCAGGTGACGGAGAGGGAGCTGAAGTCTGGAGGCTCCAACATTCAGGTGACAGAGAAGAACAAGAAAGATTACATCGAGCGAATGGCACGATGGAGGGTGGAGCGGGGGGTCATGCAGCAAGCCGAAGCCCTTGTTAGGGGTTTCTATGAG[G/A]TACAAAAGCTGGAACAGTAGACGATCCACACACAGGAAGCAATTACAGTGCCCAGCATACATGAACTCATCTTCATTTGAGATTATTGTCTTTATCCATTTCTTAGTGAATATAGACTTCTCAGTGAATGTGTTTTGGTGTATTTAAACAAAAACAGTAGATCTGTGAATCTATATTGGTCTCATGGTTCGGTTCGGTTACGATTATCATTCATTCATTTTCTTGTCGGCTTAGTCCCTTTATTAATCGCCACAGCGGAATGAACCGCCAACTCATCCAGCACATTTTTACGCAGTGGATGCCCTTCCAGCCAGGGCCGACGTGTCCATAGAGGCGACCTAGGCGGCTGCCTAGGGCGGCAGTATAGAGGGGGCGGCGTCCGCGACACCTCCCTCACCACCTGCGTCCTCAATTATATTCGCGCATAGGCAACAGAATAGAGGTCCGCGACACTTCACTTCATTTTTATAACCAGTCACTTTCGTTTTCACATTGGGGTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa30017

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000090301	Nonsense	393	494	11	12

Genomic Location (Zv9):

Chromosome 24 (position 218902)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	182785
GRCz11	24	734559

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGTATTAAAACAGGAGTATCAATGTCCATGTAAACATCTCCTGCAGGTTA[T/A]CATGATGGCCACATGGTGATGCGCTGGTTCTGGGCGGCAGTGGAGCGCTT

Long Flanking Sequence:

TGACCATCTCTCTCTCATTAGCATAAACAGCAGCTCTGAGTGAGAAGCAGCCGTCTGTGCACTAGTGTCCATCTCTCCCTCATTAGATCAAGTTTTTCTTTCTCCCAAATGAATCTAGATTTTCCTTTTGACATAAGATTATTTTTCTGACCCCATTTGGCCTGTTTTAAGGAAAAACTCACTTAATTTTGGCTTAAAACTAGACAGTATGAGTTTTTAGACTGTAAATCTGACACTTTTCTCTCTTCTGGCTGCCGTTATCAGTCTCACACTATTGTTTTCCTCTTTCTGAAAGTCTTGCTAACACCATCCTGGAGTTTTTCTGTCATTATTTCAGCAAATAGGATTGTAAATAAATGATTTGCTGTGCACTCCTACTACTGCGCTCTGCACTATGACCACTTCTGCTGCTGAGAAACACACGTGAAAAGACTCTCTCGTTGTCTTCATTGTATTAAAACAGGAGTATCAATGTCCATGTAAACATCTCCTGCAGGTTA[T/A]CATGATGGCCACATGGTGATGCGCTGGTTCTGGGCGGCAGTGGAGCGCTTCAATAATGAGCAGCGGCTGCGTCTGCTGCAGTTTGTGACGGGGACCTCCAGTGTTCCCTATGAGGGATTCGCAGCGCTGCGCGGGAGCAACGGCCTGAGGCGATTCTGCATTGAGAAGTGGGGAAAAGTCACTTCTCTGCCCAGGTATAATGCAGATATTACACAGACACAAATGATCACACAGATCAGATATTGACGGAAATGTTTTTGAAGAATTTAATAAGCATTCTTGATGTTATAAATATCGTAAACACACTTTACACAATACTGAGAATGGACAATGAAGATCTGCAGTGTAAATTCAGCCACAGTGCGATCCTGAAAGCCAAACATTAGTGTCACCCTGGCTTGATCTGCATCCAGCGCTTCACCTTGACATTCATTTTCTCTGTTGGTCTGGCAAAGCGAAGGGCCTGCGGGTTAAAGCCTGGCGCCGTCAGCACTAAAGCA

Associated Phenotype:

Not determined