Busch Lab

ZMP

LOC100000526

Ensembl ID:
ENSDARG00000053439
Human Orthologue:
SEC24A
Human Description:
SEC24 family, member A (S. cerevisiae) [Source:HGNC Symbol;Acc:10703]
Mouse Orthologue:
Sec24a
Mouse Description:
Sec24 related gene family, member A (S. cerevisiae) Gene [Source:MGI Symbol;Acc:MGI:1924621]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa14962 Nonsense Available for shipment Available now
sa37388 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa37389 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa14962
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099278 Nonsense 923 1097 18 40
Genomic Location (Zv9):
Chromosome 21 (position 44346609)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 45601831
GRCz11 21 45705853
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTTCGTCCTGCTGCTCCTCCAGAAAGCGTTCGGCACGAGCAGCGCCACA[C/T]GACTGGACGAGCGCATGTTCTGCATGTGTCARCTGAAGCAGCAGCCGCTG
Long Flanking Sequence:
TGGCGCCCGCATGCCTGCGTCTATTCCCGCTCTACATCCTGGCCCTGCTCAAACACGTATGACACACACACTCGCTCGCTCACACATGACATCACACACACCACCTAGGCTTTGGGTAGTGAACTGATGTACAGATCTATTCAAGCTAAAACACAATAATAACTCATCGATTATAAACACATTCAGGCCCAATCCCTGTTAGTTAATGCAGCACACGGGTGATCAACACTCAGTAATGCAGGATGAGCTGCTGTCACGGCTTCACTATCAGTACATGTGATTATAATGGAAGTCAATAGGGCAGAAACAGCAGCAGCGTAACCTAAAGAGAGTCGGTCTGAACAGCACACGAGGAACTGGAACCATTAATGAAACTAAATGAAATGTTCAGCAAATTTAACAGCAGTTTAAAATCAACACTAATGTGAAAGTATGAGAGTGTAATCGTACTGTTCGTCCTGCTGCTCCTCCAGAAAGCGTTCGGCACGAGCAGCGCCACA[C/T]GACTGGACGAGCGCATGTTCTGCATGTGTCAGCTGAAGCAGCAGCCGCTGGCGTACGCCATGCTCAGCATACACCCCAGCCTGTACCGCGTCGATGACCTGACGGACGAGGTCAGTACACACACACACACACACACACACACACACACACAGGGATAGTGCTCATACTTTAGTCCCTGTCAGAAGTCTCCATTTTGGACTCATTGCAGTCTATTCAGGGCGTTTGATCCGCTTTCACTGCAGTGGATTTCTGTTGATTGCAGCGAGTCTGTGCCGGACACATCAGTGTTGGAGAAACTTACATCTGACAGTAATGCGTTACAGTAATGAGGATATTCCCCAACAGAGTAGCTAGTTGTGTTACTTGGTGACTTTCTGTGGTGAATATTGTGTTTTAGGTTACTTTTCCTTCCCTGGCATCAGGCTGGAGCTCGTCAGGGTTTTCTTCTTGTTTGACTAGAGGAGCTCTGCACTGAATAACCTCCACATAACACACATCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37388
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099278 Essential Splice Site None 1097 None 40

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 21 (position 44367502)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 45580938
GRCz11 21 45726746
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGGTGGGCGGACGGAGCGTGGTGTGTTCAGATGTGGAGCAGCATGTGG[T/G]GAGGGAGCACACACACACACACACACACACACACACACACACACACACAC
Long Flanking Sequence:
TGCAGTATAAAACAATGGAAGCCTATGTAATGTCCCCACAATTCACAAAAACAAATTTGTGTGTGTGTTCAGGTCGGGTCACTAATCTGCGCAGGGTTACATATGTGGTGATCGACGAGGCTGACCGAATGTTCGACATGGGCTTCGAGCCGCAGGTCAGTCACCTGTGTGTGTGTGTGTGTGTATTTGTGCGGGCGTGCGTGTGTGTTTATAATGTTGATTCATGAACACACTCGTGTCCAATCTACTGAAATTTGACTGATCCCTCTGTGTGTCTGTTTCTCTCGCTCACGCTGTCTGTGTATGTGTGTGTCTCTCTGTGTGTGTGCCTCAGGTGATGCGTATCGTGGATAACGTGCGACCCGACCGTCAGACCGTCATGTTCTCCGCCACGTTCCCCCGCACCATGGAGGCTCTGGCCCGCAGGATCCTGTCCAAACCTGTGGAGGTGCAGGTGGGCGGACGGAGCGTGGTGTGTTCAGATGTGGAGCAGCATGTGG[T/G]GAGGGAGCACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACTGATTGGTTATTTAGCAGCAAATGATTCAGCTATTGTCCGTTTGGTGTGGTCATGTGTAGCTGATTGGTCCAGACAGAACCAGACGTGAGCTGACAGCACAGTTGTGTTTGATCAGTGACCAGCCTTACACACAGAGAAATACAAACCAAACACAAACGCACACAAACGGACACACACTGGGTTCACATCAAACATGGAAATAAGTGTTCACAAGTTACATACAGACATAATAAAATAGACATAATATTTACATACGCACATACATTTATTTATATTTATTTTGTCTGAAAGCTGTCATACGAGTGATCCGCTGATGAATCGCGGCTTTATATGCTCCAGTGTGCCTGTTGTTTTGGTAAACAGCTGTGAGTTCGGTGAACCTTTATGGTCAATCACAGTCATTTCTGTTGAGCTTGTAAACACAACAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37389
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000099278 Essential Splice Site None 1097 None 40

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 21 (position 44370243)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 45578197
GRCz11 21 45729487
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCGGCGCTCGGCCTGCACGACTCTGATGATGAGGACACCGCGCTCGACG[T/C]GAGTCTCCGTGTGTGTGTGTGTGTGTGTGTGTGGCACTGTCTGTATAACG
Long Flanking Sequence:
TCCTGAAGGCTCTGGAGCTGTCGGGATCGTCCGTCCCCGCGGAGCTCGAGCAGCTCTGGACAAACTTTAAAGAGCAGCAGAAAGCAGTAAGAGAACAGCAGCATCAGCACAGCTCAACACAGAGCACAGCACCACTGATGGAGAGAACACCGTCTGCTTTCTGTTACTCGTTTAAACATGCGCTGCCTAATTAAACATGCGCTCATTTACATACATGCATGCAGGACACGCCTGTAGACGCTGGAGGACAGCATGATGCACTTGACCAGTTTTAGTGAAGGTGTTTACTGATGTGTGTGTGTTTGTTTTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTCGTCAGGAGGGGAAGATCATCAAGAGCAGCAGTGGCTTCTCTGGGAAAGGCTTTAAGTTTGATGAGACTGAGCATGCTCTGGCCAACGAGAGGAAGAAGCTGCAGAAGGCGGCGCTCGGCCTGCACGACTCTGATGATGAGGACACCGCGCTCGACG[T/C]GAGTCTCCGTGTGTGTGTGTGTGTGTGTGTGTGGCACTGTCTGTATAACGGTGTGTGTTTGACTGGGTGTGACTGTCTGTATAATGGAGTCTGTGTGCGTTTGATGGGGTGTGTGTTACACTGTTTCTGTGACTGTCTATATGGTGTGTGTGAGACTGTGTGTCTGACGGTGTGTGTGTGTGTGTGTTCTCTGACAGATCGATGAGCAGATCGAGAGCATGTTTAACTCTAAGAAGCGGGTGAAGGATTTCTCGGCTCCGGGCTCCGTGTCTGCGGGGTCTGCAGGTGGTGTGAGCGGCTCCGTGTCTGCAGTGTCCGGCCTGGGCAGTCTGAGCACTCCGTCTGCCGGAAACATCCAGAAGCTGGAGATCGCCAAGAAGCTGGCGCTCAGGATACAGGCGCAGAAGAACCTCGGTGCAGAGGCGCAGGTCAGAACACACACACACACACACACACACACACACACATGGGCTTTATCTGAAACTACACTCAGCATGTGT
Associated Phenotype:
Not determined