Busch Lab

ZMP

dab1a

Ensembl ID:
ENSDARG00000059939
ZFIN ID:
ZDB-GENE-060528-1
Description:
disabled homolog 1a (Drosophila) (dab1a), mRNA [Source:RefSeq DNA;Acc:NM_001040685]
Human Orthologue:
DAB1
Human Description:
disabled homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:2661]
Mouse Orthologue:
Dab1
Mouse Description:
disabled homolog 1 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:108554]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa14868 Essential Splice Site Available for shipment Available now
sa43385 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa15478 Essential Splice Site Available for shipment Available now
sa36975 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa36974 Missense, Splice Site Mutation detected in F1 DNA Not yet available
sa45689 Missense, Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa14868
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083906 None None 543 None 17
ENSDART00000083908 Essential Splice Site None 541 1 24
ENSDART00000145841 Essential Splice Site None 537 1 13

The following transcripts of ENSDARG00000059939 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 8596902)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 8431171
GRCz11 20 8418910
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGGATTTTTATCATGAGAAGTATGGAATCTGAACGCACTACTTTAAAGG[T/C]AAGRCGGTTTGTCTTGTGGATGACATATGGAAAGAAAAACRGCGCTGTTG
Long Flanking Sequence:
GGTGCTCGTGCATGTTGAGTCTCAGCAAATAAGATGCGCTTCATTTCTGATCTCTCATCCATCCCCCCCAAACGCATCCTTTTTGTCTTTATATTCTTTTGCACATCTTAGCTTTTTGGCATCGAAAACTCTCGCTCACCCCTCCCACTCCTTGCGTTTTCCCCTGAAAGCAAGAAACCAGGACAGCGCGGCGCGCGACGGGTTAACGCGCACTCACGCTCGTGATTGGCTGCGGGAGCGGCGCTTTTAGAGAGAGGTAACCAGGCAACTTCAGCTGGAGCAGCGGAGAGAAAGAACAGGGTAAAGGGGAAAAGAAGCGCAAAAATCCCATCAGTTTTGGTGTGCGATAGAAAGGATGTAGTCCAGGTCTGTGGCTGTCTGTCCCCGGCATGGGAAAGTGGATTACTGCTCTTCTACAGACGGTAGAGACTGGATACGGAGTGATTGCGCGTGGATTTTTATCATGAGAAGTATGGAATCTGAACGCACTACTTTAAAGG[T/C]AAGACGGTTTGTCTTGTGGATGACATATGGAAAGAAAAACGGCGCTGTTGCAGTGAAACTTGTCCATGTGGAACGCGAGGACGCCTCTCCGTGCTTCGGTGATGGAGTTGTGTCGGTTGATTGAATTCACGCATCTAAAGCGATTGGAAAGATATTAAACAGTTACCACATATTTGGCTTGCGAGGAAATGAGCGGAACCAACTGCCACCAGTTGACGGTGATCATGCGTCCACGCGCGTATGGAGAGGAGCGGCGTTTGCTGCATTGACATCCATGTTCTGCCCCGCACGAGAGCCATTGATCAACTGAGATTTACTACAACGCTTCATATGTATCACCCTATTCATTCACAGCCGTGCAGAGCTGGTATATACACTTAATTAGTGCTGTATGCGCATATAAACTGCAGTGGAAAGGTTCTCGGTATTCCTGCTCGGGTTAAAACGCACGAGTGTCAAAGAGCGTGAGATGTCAGTATGCCGAAGCGGATTACGCTAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43385
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083906 Essential Splice Site 146 543 4 17
ENSDART00000083908 Essential Splice Site 146 541 5 24
ENSDART00000145841 Essential Splice Site 146 537 5 13

The following transcripts of ENSDARG00000059939 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 8374323)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 8208592
GRCz11 20 8196331
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCGGGAAAGAGGGAAACCATCGGTTTGTGGCCATCAAAACGGCTCAGTCT[G/A]TAAGTACTCAGGCCTGAGAATTGCGAGTGTCATAAACCAGACTTTGTATA
Long Flanking Sequence:
AAGCTATGATCATCATCTTTCTAAAACCTTTTTTTATTCTTGCTTTTTTTGTGTGCACAAAAGTGTCCTTGTAGCCTCATAACATTCCGATTGAATTATTAAAGTTTTTTTTTTTTTTTTTTTTACTATTTTTGGTACCTTTCTGGACCTTGAATGTGTCTGGACTGTTACTGTCTATGGAAGATAAGAGAGTTCCTGAATTTCATCTTAAAATATGTTAATTTGTGTTCTGAAGATGATTGAAGGTCTAAAGGGATTGGAATAATACGAAGGAAAGTCATTAATTTTTTGGGGTGGACTAACCCTTTAAAGTTGATCTCCTCAGGCTGTATATGTCATTTTAAAATGCTTCTGGTCTTTACCTACAGGTACTTCAGCACCATCATGCAGTTCATGAGATTTCCTACATCGCGAAGGATATCACGGACCACAGAGCCTTTGGATATGTATGCGGGAAAGAGGGAAACCATCGGTTTGTGGCCATCAAAACGGCTCAGTCT[G/A]TAAGTACTCAGGCCTGAGAATTGCGAGTGTCATAAACCAGACTTTGTATATGTGTTGTCTGTTTTAAACTTGGTTTAGTTAGATAAACATTTTAATTCAACCTGCTCATTCAGACAGAACCTTGCTGCCACTGATCTTTTGGTTGTAGATTAACATTTAAAATAATTACTTACTTCATTTTCAATTCATTTTCTTCTTTAAAAACATCAATTGCTAAATGTGATATATGCAGTTGTAATTGTTGTGTTATTAAAATTGTATGTAAATTTAAGAATTTTATTTAATAACATTAAATTACATTGAATGTGGAATTTAATCATTCCACATTTTAATGAAATGTGATTAAATGTAAATATATAATGTATATACAATATAAAAGTGTCACTAGTCAACAAATAAAATAATTAAGTATTAATTATTAAGTATCTATTAAATGTCACAATCTGGCATATGTAAAGTGATATAAATATGACAATACATTTAAACAGACTGTATATCAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15478
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083906 Essential Splice Site 186 543 None 17
ENSDART00000083908 Essential Splice Site 186 541 None 24
ENSDART00000145841 Essential Splice Site 186 537 None 13

The following transcripts of ENSDARG00000059939 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 8371368)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 8205637
GRCz11 20 8193376
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGAGAAGAAAGCTCAGAAAGACAAACAGTGCGAACAWGCTGTTTATCAGG[T/A]AACACWCTCACCATAAACCTTYATGAACTCAAAGCCTTAAAGAGAATTCA
Long Flanking Sequence:
ACATACATACATACATACATACATACATACATACATACATACATACATACATACATACTTACTTACTTACTTACTTACTTACTTACTTACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATACATGATAGTTAGCTAGCTAGCTAGCTTCTGAAATGCTTTTATTCCGGTTATGCAGTTGCCAGCATGAACGGATCATTTTCATTTCTAACTGTGAGAAGTTGGTGTCAGTCTTTTTTCTCTGTGTTTGTGAATCTCTATGTCTTTGCTCATCTTTCCTCGTGTGTTCTCAGGCTGAGCCGGTGATCCTCGACCTCCGCGACCTTTTCCAGTTGATTTATGAGATTAAGCAGAGGGAGGAGATCGAGAAGAAAGCTCAGAAAGACAAACAGTGCGAACAAGCTGTTTATCAGG[T/A]AACACACTCACCATAAACCTTCATGAACTCAAAGCCTTAAAGAGAATTCAGTGTTTGTGAAGCTCTTACACGAATAGGCATCAGCGGGCAATTGAAGAGCAACAACAAACTCAAAAAGGGATGATGAAATATGCAATACAATAGGATGAAGACACGGAAAACAACACATTTCGAAAATAGGACATATATATTATTTATGTCAGAGAGTAGCATAATTAGATATAATATGAGGCAGAGTGCACGCTGAGATTAAAAAAAAATAAAAAATTTATACAACTGTTGCTTTTCACATTGTAAATTAATGAGATCTTGGGTAAAACCTAAAGTAGACTGCACAACAATACCTTACTTTTATGTGTATCTATAAATAATGAAATTTATTTCATGACATGATTTTCAAAAGTGGCTGATATTCAAAATAATTTTATGGGTTTAGCATTTTAATGTATATTTATTTCACCCATTTATTTTAATTATAATTTTTATAAACACTTAGATTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36975
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083906 Essential Splice Site 199 543 None 17
ENSDART00000083908 Essential Splice Site 199 541 None 24
ENSDART00000145841 Essential Splice Site 199 537 None 13

The following transcripts of ENSDARG00000059939 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 8367606)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 8201875
GRCz11 20 8189614
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTCCTGCAGACGATTCTGGAGGAAGATGTGGAGGATCCCGTGTATCAGG[T/C]AACGCTTTGAAATAAACCGTGAATCATTATGTCTGACTGAACGATTGCCT
Long Flanking Sequence:
TTTGTCATTTGCATCTGTGTTTCTCAGCCACGTTCCTGGAGGACCACCTGCACTGCAGGTTTTGGTTGTATCCTCTGTCTGCCACACCCATCAAGGATCTTTCAGTCTCTGCTTATGAGCTGATGATCTGAATCTGGTGTGTTTGGTTAAGGAGACATGGAAAATGTGCAGAACCGGAGGTCCTCCAGGAACGTGGTTGAGAAACACTGATTTGCATTATTACAAATTGTTAGAAATTATTTTATGGGGGAATCATAATATTTTGAGCAAGAGATCAAAAAGTTTAAACACTTTGTACATTCTTTTCAGAGCCTTCTTTGTTCACGTTTAACAATACCATAGGGGAGGGCACTGCTAATGACCAGAAACCGTCTCTATTTTTTCTTTTTCCTGATCTTCTGCTCTCCACTTTTCCTTCTTGTCTCTTCTTTCTGCTCTTTTTTTGTGATCGCTCCTGCAGACGATTCTGGAGGAAGATGTGGAGGATCCCGTGTATCAGG[T/C]AACGCTTTGAAATAAACCGTGAATCATTATGTCTGACTGAACGATTGCCTCTCGCTGTCACATTAAACAGGGCTCCTGCTCAATGATATGCCTTTAATCTCATCCACAGAAGTAAATAATTCCACTCCATTTTCTCTACTCTCTTCTCACTCCTCCTGAACTAATAACTCTTGTTATTTCATCCTTTGTGTGTGGAAATTAAAGGAGAATCATCGCTGTAATGTGTTAACTTTTCCTTTGATGAATTGGGTGTTTTCTGATTAAACTGATGCAGTAGCGTTTTTGGGAGCCTCCTTTGTTTTGTTTTTTTTGGTTTTTTTTGTACTGAAAACAGACAGCTTTAACACATCTCATCTGGGCTGCGTGTGTGTGTGTGTGTGTATGTTTACATGCACTGCATTGGCTTTCCGTATTGTCCAGTGTGCATCATATTGGGAATGAAATAGTCTACTGTATGTATGTATTCTGTAGATTCTGTGTGTGATTGTAGTTTTTTAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36974
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Missense, Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083906 Splice Site None 543 None 17
ENSDART00000083908 None 444 541 11 24
ENSDART00000145841 Missense 445 537 10 13

The following transcripts of ENSDARG00000059939 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 8332139)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 8166408
GRCz11 20 8154147
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGACACGGATGACTGTGACGACTTCGATATCTCGCAGATGAACCTCACA[C/T]CCGTCACCTCCACCACACCCTCCACCAACTCACGTGAGTAGTGCCAATTG
Long Flanking Sequence:
GCGTCCAATCCCCAGTGCAAGTTGCGCAGGTCTTACCGGGCACTCAGCCTCTAATCTGGGGTCAAGCCAACCTTTTCCCTGCCACTCAGCAGCAGTGGGCTGCGATGGCTGGGGCTCACTTTTCTCCTGCCGCTTTCATGCCTGCCCAGACAGTAGGACCACTTCCTGCTGCCATGTTTCAGACACTGGCTCCTATGGCAGTGCCGGCATCCTGCGAGACGCCCACAGCGGCCATGGGTGGAGCCGTGGCAGGAACCTCGGCCTCCACGGCCTCCAGTCCGCAACATGGAGAGCGCACACTGCAGAGACAGGCAAAGATGAGCAAGGAGATGTTTAAGGAATTCCAGATGGCAAAGCCACCGGCCATGCCTGCCAGGAAGGGCGAGCAGCCTAGCCTATCCTGCACCACAGACGCTTTCTCCAGCTACTTCAGCAGAGTGGGAATGGCGCAAGACACGGATGACTGTGACGACTTCGATATCTCGCAGATGAACCTCACA[C/T]CCGTCACCTCCACCACACCCTCCACCAACTCACGTGAGTAGTGCCAATTGTTCTCTGGTTTCAATAAGGGTTGGGGTTGTTTATATAGAAATGGGGGCAATAGGTTAAAACACTGCAACCAATTGCATGTTAAACCTACGACTTTAGCATTGTTAGTATCTACTATACCAGGGATTCTCAACCTTTTTCACTTTGAGGCCCACCAAACTGGTTGTCTTTATTTTAAAGCTTTATTTAATAGCAAAACGTTTTTTGCTATTTTTCTACATCATTTTATAAAAAAAAACTCTAAACATTGTGCATTTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAATATTATTATTTTATTTTTTATTTATTTAAATATAATATAAAATATAATAATATATATTTTATTATTATTTTCTTAATGCACAGACCAATTTAAAGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45689
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Missense, Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083906 Splice Site None 543 None 17
ENSDART00000083908 Missense 445 541 12 24
ENSDART00000145841 None 445 537 10 13

The following transcripts of ENSDARG00000059939 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 8332137)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 8166406
GRCz11 20 8154145
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACACGGATGACTGTGACGACTTCGATATCTCGCAGATGAACCTCACACC[C/T]GTCACCTCCACCACACCCTCCACCAACTCACGTGAGTAGTGCCAATTGTT
Long Flanking Sequence:
GTCCAATCCCCAGTGCAAGTTGCGCAGGTCTTACCGGGCACTCAGCCTCTAATCTGGGGTCAAGCCAACCTTTTCCCTGCCACTCAGCAGCAGTGGGCTGCGATGGCTGGGGCTCACTTTTCTCCTGCCGCTTTCATGCCTGCCCAGACAGTAGGACCACTTCCTGCTGCCATGTTTCAGACACTGGCTCCTATGGCAGTGCCGGCATCCTGCGAGACGCCCACAGCGGCCATGGGTGGAGCCGTGGCAGGAACCTCGGCCTCCACGGCCTCCAGTCCGCAACATGGAGAGCGCACACTGCAGAGACAGGCAAAGATGAGCAAGGAGATGTTTAAGGAATTCCAGATGGCAAAGCCACCGGCCATGCCTGCCAGGAAGGGCGAGCAGCCTAGCCTATCCTGCACCACAGACGCTTTCTCCAGCTACTTCAGCAGAGTGGGAATGGCGCAAGACACGGATGACTGTGACGACTTCGATATCTCGCAGATGAACCTCACACC[C/T]GTCACCTCCACCACACCCTCCACCAACTCACGTGAGTAGTGCCAATTGTTCTCTGGTTTCAATAAGGGTTGGGGTTGTTTATATAGAAATGGGGGCAATAGGTTAAAACACTGCAACCAATTGCATGTTAAACCTACGACTTTAGCATTGTTAGTATCTACTATACCAGGGATTCTCAACCTTTTTCACTTTGAGGCCCACCAAACTGGTTGTCTTTATTTTAAAGCTTTATTTAATAGCAAAACGTTTTTTGCTATTTTTCTACATCATTTTATAAAAAAAAACTCTAAACATTGTGCATTTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAATATTATTATTTTATTTTTTATTTATTTAAATATAATATAAAATATAATAATATATATTTTATTATTATTTTCTTAATGCACAGACCAATTTAAAGCTCC
Associated Phenotype:
Not determined