ZMP

zgc:92903

Ensembl ID:

ENSDARG00000044125

ZFIN ID:

ZDB-GENE-040718-162

Description:

thioredoxin [Source:RefSeq peptide;Acc:NP_001002461]

Human Orthologues:

TXN, TXNDC2, TXNDC8

Human Descriptions:

thioredoxin [Source:HGNC Symbol;Acc:12435]
thioredoxin domain containing 2 (spermatozoa) [Source:HGNC Symbol;Acc:16470]
thioredoxin domain containing 8 (spermatozoa) [Source:HGNC Symbol;Acc:31454]

Mouse Orthologues:

Txn1, Txndc2, Txndc8

Mouse Descriptions:

thioredoxin 1 Gene [Source:MGI Symbol;Acc:MGI:98874]
thioredoxin domain containing 2 (spermatozoa) Gene [Source:MGI Symbol;Acc:MGI:2389312]
thioredoxin domain containing 8 Gene [Source:MGI Symbol;Acc:MGI:1914652]

Alleles

There is 1 allele of this gene:

Allele Name	Consequence	Status	Availability
sa14838	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa14838

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000064789	Essential Splice Site	87	107	4	5

The following transcripts of ENSDARG00000044125 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 7 (position 25524747)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	7	24086499
GRCz11	7	24357656

KASP Assay ID:

1641-0481.1 (used for ordering genotyping assays)

KASP Sequence:

GTGGCATCTCATGCATGCCAACATTCCATTTCTACAAGAATGGAAAGAAG[G/A]TACTGTAAATCACCCTGCCATGGTTTCTTRAGTKAGCTATTATTTGGCAG

Long Flanking Sequence:

AGTTCTTTGGAAAAAGTAACTCAAAAATGACTTTGAACAGTGATGCATTATTATAGTGTAAGTATTCGATAAAGTAATATAGTTAATTTTTGAATTAAGTAATTGTAACTAATAACTACTTTTAGTAACTAGCACAACACTGTTTTTAAGTTTTAGGTTTTTTTTGTGGTATTTTTCTGGACTTTGAAAGTTGCAGGTGTTTATTGAGGATAACAGAGCTCTCAGATTCCACATAAAATATCTGTATTTGTATTCTGAAAACAAATGAAGGGATTAGGGGATAGGAACAAGCTGAGTGTGAGTAAATAATAACAACATTTTCATTTATGGGAGAACTAACCTTTTTAGAACTCTTTTAAAAGTCGCTAGACTGAAAAGAAGCTAATAAAAATGTTTATCACCTAATTTGACTTCCACTTCTTCACTCTGTCTAGGATGTGGCCGCTTTATGTGGCATCTCATGCATGCCAACATTCCATTTCTACAAGAATGGAAAGAAG[G/A]TACTGTAAATCACCCTGCCATGGTTTCTTAAGTTAGCTATTATTTGGCAGTTAAACTGAATTGTTATCGCCTATTGTCCTGTAACTGACTGTGATTTACTTGTTTTGCAGGTTGATGAATTTTCTGGATCTAACCAATCCAAGCTGGAGGAGAAGATCAACTCGCATAAATGAAGAAAAACAAAAACACACAGTAATAGCTGAAGACAGAGAATACACTTTCTGAAATCCTCAGAAGTTTAGGTTTAGAACAGAAATTCGTTCTCTGACTCATTCATATTTTGACAGCTACATTTATATGTTTTGTTTTGTGTTTATATACAGAAACAGAAGTTATACGTTTATTTTTAGTTCAATATTTTAGCCCAGTAATGTATTTTATGTTGGCTTTGTATGAAATGAAAACAATAAAAGAAATGAGAAGTCGGATGTTTGTGTCGATCAGATTATCCAAGTCAAAAAATAAATAAAAGTGAAACAGTCAAGTAAAACAAACTGAAA

Associated Phenotype:

Not determined