Busch Lab

ZMP

heg

Ensembl ID:
ENSDARG00000018441
ZFIN ID:
ZDB-GENE-040714-1
Description:
Protein HEG [Source:UniProtKB/Swiss-Prot;Acc:Q6R8J2]
Human Orthologue:
HEG1
Human Description:
HEG homolog 1 (zebrafish) [Source:HGNC Symbol;Acc:29227]
Mouse Orthologue:
Heg1
Mouse Description:
HEG homolog 1 (zebrafish) Gene [Source:MGI Symbol;Acc:MGI:1924696]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa14693 Nonsense Available for shipment Available now
sa14122 Nonsense Available for shipment Available now
sa41490 Nonsense Mutation detected in F1 DNA Not yet available
sa41491 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa14693
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004462 Nonsense 95 977 2 13
ENSDART00000140325 Nonsense 95 841 2 12
ENSDART00000147938 Nonsense 95 935 2 11
Genomic Location (Zv9):
Chromosome 9 (position 39744537)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38882433
GRCz11 9 38692228
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACTCGTTCTTCTTTAAYTATCCAATMCAGGACATTCACCAAAACCTTTA[C/T]AAACCTCTACAAATGCAGCGGATTGGAAGACCAGTATGACCTCAGATGAG
Long Flanking Sequence:
TATCCAAGGACGATTTGTCTACCATGAAGGTAATTTTACGCCATCTGACTCATTAAACTTATTGGACTCACATATACAGTATTCCTCCTATCCAGTCAGCAGTCCTGCTGATTATAACTTTGCCTGTGTATGAACTCCATGCAGGCAGCGACAACGCTGTGATATGGACTTTGCTAGGTCAGCTGAAGGAAGGAAACAGCAGGTCCCAATGGGTCAGATCCCCTCCATTTTTAGGGCTCAAGCTTTTGTTAGGTTAGACGAGCTTGGCTGCCAATTGTTCTCCACCCAAAATCATTACATCCGCAGTCACTTCTGAAAACATCTCACATGGTTCATGAGGTTTCCCAAGACTCACTCGATATGAAGCGCACCCTAGTGGCCATCTAAAATCCCCCCTACCTCAGTTTCAGTATTATTTGCAGTTTGACTGATTTACAGTACACATTTTCTAACTCGTTCTTCTTTAATTATCCAATACAGGACATTCACCAAAACCTTTA[C/T]AAACCTCTACAAATGCAGCGGATTGGAAGACCAGTATGACCTCAGATGAGACAACAGAACATCTTCAATCTGACACTGAGCTTACCCATAATGCGACCGCCCAATGGGAGAGTCCATCATCAGCATCTCACAGCATTACCAGCCACCATCCAGTAACAGAGACACGAACCGTGCGAGATGTAACAGATCTGATAGACATGGACACCACAGACTCAGTCTCCCACACTGATAGCACCTACATTTCCACAACCAACCGAGTTGGAGAACGCACACTGCTCTCAGTGATCTCCAACAGCACCTTTGCGTACACCCAGAACTCAAGCATCTCTGATGCAGAGTCTCAAACGTCCCCATGGGAGGAGAAGACATCAGGAGCCACCCAAGTCAATGAGGAAACTGAAGAAACTGTGTCAACAGTGTCCGAACAGACTGATCCCACTTTTGAAGACCGCAATATCACCAGTGCAACTCTGGAGACTGGGCGGTCAACATTATTCCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14122
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004462 Nonsense 671 977 5 13
ENSDART00000140325 Nonsense 671 841 5 12
ENSDART00000147938 Nonsense 671 935 5 11
Genomic Location (Zv9):
Chromosome 9 (position 39748890)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38886786
GRCz11 9 38696581
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATAAGATAACTCTGTCTGCTTTGGTTTTACCTTGCAGTCAAGACATTTT[T/A]GGGCACTTTCACAGTCAACAACTCTCTTCATCTCAGAAATTTAGGTCTGC
Long Flanking Sequence:
TGTGCACAATTACAACAACACTTTTTCCTTTTAGGTCATGTATGTGGACCTAAAACCTGTGCAAATGGAGGTCATTGTGTTAGATCAGCTGAAGGAAGTTACTACTGTCAGTGTCTCTCCGCATGGACCGGACCCTTCTGCACTGAAGGTAAGAATAAGCCCATTACATATCATTTGTTCACATATTACAACATGCCACAATATTCAGACTTTTGAATTTGTTCTGCTTGCATCAGTGCATGGGATAAAAACAAATTGATTGGTCTATGTTCATTTCTCTAGATGTGGACGAGTGTGTGAACAGTCCATGTCCTCAGGGTTCAGTGTGTGTCAACACAGGTGGTTCTTTCAGCTGTGAATGTGACCTGGGCTTTGACCTGGAGGATGGCCGCAGTTGTACACAAGGTATGTGGTCAGTATTTTAGAATAATTTCTGGAGAAGATAACAAACATAAGATAACTCTGTCTGCTTTGGTTTTACCTTGCAGTCAAGACATTTT[T/A]GGGCACTTTCACAGTCAACAACTCTCTTCATCTCAGAAATTTAGGTCTGCACGAGCTACACAGAGAGATCCAACAGCTGGTACGCAACAATATGCTGCAACTTGCATTATAAGCTCATCTAATGCTGTATAGCAACCATTATGGAAATGGGTTGAAGATGATAAATTGATGTTGATGGAGTTTGGGTTAATTTGATACATTTGTGTATTGGTTTTTCAGCTCAATGCTTCTCTCTCCATCTTCCATGGTTATAGACGCTTTACCCTGGGTAAAAGGTGAGTTTCATAAATGATCATAAACATAAATAGCATAAAAGTTATTTGATCTCTTCATATTGTGCCATGCAATTACTGTCTGCCTGTCCATCTATCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGCCTGTCTGTCTATCTATTGTTTGTTTGTTTGTTCGAACTATCATTTGTTCTATCGTTCTATCTATCGTTTGTTATCATTATATTGTTTGTTCTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41490
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004462 Nonsense 781 977 8 13
ENSDART00000140325 Nonsense 781 841 8 12
ENSDART00000147938 Nonsense 781 935 8 11
Genomic Location (Zv9):
Chromosome 9 (position 39752416)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38890312
GRCz11 9 38700107
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCTCTTTCTGTTTAGTGGAGAGCCTGTGCATGGCCCAGAAGACCAAGTG[T/A]GATGTGCAGTACTCAGATTGCTCGGATATTAGCGGGATTCCCAACTGTCA
Long Flanking Sequence:
ATTTCTAAACTGATACAATCATAAACAGATATTCTTATTTTCAATTATGTGTGAATTCATTGCTTTTTTTTATTGTCCTCACTTGTACTTGAATGTGTATGTCCTGTGCAGAGATGGACAAGGTGTGCAAATCCCAGTGGTGAGCATGTTTTCACTCTCCTCCAATGTGACCAGCGCGGATGTTTTCAACAGCATCCAGATGTCCCTTAACAACTGCAGCCGGACATACTCGCACTGTCCCATTAAACTTCAGCACCAGCTCTCCTATCACGGTACGCATTTATCTCTAATCCCGTCCCTCTGTTCATATCCACCACTTCACTTCTCCACTCAACAGATATGATAGCACCAGTCATGACGAACACACCGATAACACTGCCTTTCATTTGGCCTCTATAATATTATTTCAAGAAGCTCTGTTTATCTCCTGGAAGCCATTAGTTCTGAAGCACCTCTTTCTGTTTAGTGGAGAGCCTGTGCATGGCCCAGAAGACCAAGTG[T/A]GATGTGCAGTACTCAGATTGCTCGGATATTAGCGGGATTCCCAACTGTCAGTGCCTTCCTGGGTACTTTAAAAGGAACCCAGAAGACATGACCTGCAGAGGTACAACATACACTTTTTTTGTTTTGTTTGATTCGATAGTGTGATTATGGCTCATGTTTAAATGAATGCCTATTGCTATGTTGTTTTAGACTGTGGAGATGGACTCAAGCTTGTTAATGGCAAATGTGTCGAGTAAGTATATTGTTTATTAATGCGTAAACAGCCGCTCAGATGTTTGGCAATAAGATATTTTGCAGAAAACAAGTCAGACATCACTGCATCACAAACTGGGTCAAAATGGGGTATGGACCATTTCAATGTGGTCGTGCCATTACGCTTGAACAACTAAATGAATGTTTCAGTCTATGTAACAGATTATATTTTAATTACATTACAATACTAATGCTGTAGAAGGAACTTTACGAAGTTAAAAATAGTCACATAAACCTTTCACCAAAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41491
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004462 Essential Splice Site 829 977 9 13
ENSDART00000140325 Essential Splice Site 829 841 9 12
ENSDART00000147938 Essential Splice Site 829 935 9 11
Genomic Location (Zv9):
Chromosome 9 (position 39752650)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38890546
GRCz11 9 38700341
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTAGACTGTGGAGATGGACTCAAGCTTGTTAATGGCAAATGTGTCGAG[T/A]AAGTATATTGTTTATTAATGCGTAAACAGCCGCTCAGATGTTTGGCAATA
Long Flanking Sequence:
CTGTCCCATTAAACTTCAGCACCAGCTCTCCTATCACGGTACGCATTTATCTCTAATCCCGTCCCTCTGTTCATATCCACCACTTCACTTCTCCACTCAACAGATATGATAGCACCAGTCATGACGAACACACCGATAACACTGCCTTTCATTTGGCCTCTATAATATTATTTCAAGAAGCTCTGTTTATCTCCTGGAAGCCATTAGTTCTGAAGCACCTCTTTCTGTTTAGTGGAGAGCCTGTGCATGGCCCAGAAGACCAAGTGTGATGTGCAGTACTCAGATTGCTCGGATATTAGCGGGATTCCCAACTGTCAGTGCCTTCCTGGGTACTTTAAAAGGAACCCAGAAGACATGACCTGCAGAGGTACAACATACACTTTTTTTGTTTTGTTTGATTCGATAGTGTGATTATGGCTCATGTTTAAATGAATGCCTATTGCTATGTTGTTTTAGACTGTGGAGATGGACTCAAGCTTGTTAATGGCAAATGTGTCGAG[T/A]AAGTATATTGTTTATTAATGCGTAAACAGCCGCTCAGATGTTTGGCAATAAGATATTTTGCAGAAAACAAGTCAGACATCACTGCATCACAAACTGGGTCAAAATGGGGTATGGACCATTTCAATGTGGTCGTGCCATTACGCTTGAACAACTAAATGAATGTTTCAGTCTATGTAACAGATTATATTTTAATTACATTACAATACTAATGCTGTAGAAGGAACTTTACGAAGTTAAAAATAGTCACATAAACCTTTCACCAAAAGTGTATCGGTGGCTGAAAAATACTAGCCATGCATGTACTGTAGTCTATTGCATTGCTTACGAGGTAAACTGAGATAAATTGCATTTGCAATAGTGTACAACTTGCATTTTATAATTTAAATCAGATAAAGGGTTATAAAAAGTTTCATTCCCCTCACTACACACTGAATGAATGAATGAATGAATCAATCAATCAATCAATCAATCATTATTTCAATTAATCAATCAATCATCAT
Associated Phenotype:
Not determined