Busch Lab

ZMP

adamts8a

Ensembl ID:
ENSDARG00000007709
ZFIN ID:
ZDB-GENE-060526-202
Description:
Novel protein similar to vertebrate ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMT
Human Orthologue:
ADAMTS8
Human Description:
ADAM metallopeptidase with thrombospondin type 1 motif, 8 [Source:HGNC Symbol;Acc:224]
Mouse Orthologue:
Adamts8
Mouse Description:
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 Gene [

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa14348 Nonsense Available for shipment Available now
sa40460 Nonsense Mutation detected in F1 DNA Not yet available
sa13542 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa14348
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098300 Nonsense 193 884 1 9
Genomic Location (Zv9):
Chromosome 5 (position 31815411)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 29576241
GRCz11 5 30176394
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCACAGCGTCTTTGGTCTTTGATCAAATGAAAGTTGACAGTCTTGTGAAA[G/T]AGAGCAAACTGAACTCCAGTGAAGATGAAGACRGCAACATGAGACGCGCA
Long Flanking Sequence:
AAGAAGAGACTGTGTTAGTAAACCGTACATTTAGGAAAGGTCTTTTTTGGAGAAGTGAAGAGAGACAGCATTTTAAGCTCAGTGCGTTTGGCCACCTTTTCCTGCTTGACCTGTCTCCGGACAGCAAGTTCGTGTCTCCAGTTTTAAACGTCCAGCGCATTAAAGCAAAGAATCTCCGCTCTGTCCTGGACGCCTCCAGGAGCGGGGGTGCTCTCAGGGATGCCACCCTTTACCCAGACAGCGGTGCGGACCTCAGAGACTGCTTCTACACCGGCACGGTAAACTCTGAAAAGGAATCTGTAGTTGCTGTCAGCTTGTGCCACGGCATCCACGGCACCTTCATAACACAAGGGGTCGAGTACTTTATTCACCCTAAAGCAAGTGTCCAGACCACCGGGAAACATTTTCCGCAGGTGCACGTCATCAAGAGGAGAGCTGTTTCCAACAGTCGCACAGCGTCTTTGGTCTTTGATCAAATGAAAGTTGACAGTCTTGTGAAA[G/T]AGAGCAAACTGAACTCCAGTGAAGATGAAGACAGCAACATGAGACGCGCAAAAAGATTCGTGTCCGCTGCGAGATACATCGAGACACTGGTAGTGGCCGACGCGTCCATGACACGGTTCTATGGGGATGAGATAAAGGTGAGTTAAGGGTCAGGGGAAATGGTTAATGGTTGTTATTAGTTATGCGCCTAACTTTATTCAACGCGTTTTTCAGTCATCTGATTCATTCTGAAAATGTTAACAATTCCTGAATCGACTGCTAATCATTTGAGAGGCTTTAAAACCTGCTGTAACAAGTGTAGACAGTATCCTTTATTATTATTATTATTATTATTATTATTATTGTTGTTGTTGTTGTTGTTGTTGTTTTTGTTGTTGTTATTGGTGTAGACCAATTTCATATCAAATAATGGTAAAAGTGATAATATTAAATATCTGTAAAAATGTTTTCTATATTTATATTAAAACCTAACTCTGCCAAAAAAGTGGCATAATCTACTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40460
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098300 Nonsense 588 884 7 9
Genomic Location (Zv9):
Chromosome 5 (position 31798761)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 29559591
GRCz11 5 30159744
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTGTGTCCTTTTTTTAATCCACAGGAAAAAGCTTCAGAGAGGAGCAGTG[T/A]GAGAAGTATAACAGTGACCGTTACATGGACATTAAAGGGAACATAAAGCA
Long Flanking Sequence:
AAACAAAATTTGTTATATATAAACAATATATATATAATTTACAATATCATTGTACTGTATTTTGTACTTTGTTACATTTTATTGTGAAATCTAACAGCCTCTATTTTGTGTCCCAGGTGCCCGTCAATGGTGGATGGGGAGAGTGGGGCCCTTGGGGGCCATGTTCACGAACATGTGGTGGGGGTGTGGAGTTTTCCCATCGAGAGTGCACTTCTCCTGTACCACAGAATGGAGGATTGTACTGTGTGGGACAGAGGGTCAAATACCAGTCCTGCAATACTCAGACCTGCCCAGAAGACCATGGTAACATTTTATAAATAAACCTCCATACTCACTTTAGATAGCATAGGTCGCATTATTGAGGGTTAGAGAATGAGTGAGTGGAGAGAATGAAGCCATGAGGTCAAAAGACCGTGCAGTTTTCTTATAACATTTATTCTCAGAGATGCACCTGTGTCCTTTTTTTAATCCACAGGAAAAAGCTTCAGAGAGGAGCAGTG[T/A]GAGAAGTATAACAGTGACCGTTACATGGACATTAAAGGGAACATAAAGCAGTGGATCCCCAAATATTCTGGTGTCTCTCCACGAGACCGCTGCAAACTTGTCTGCCGAGCCAAAGGAAGCAATGAATTCAAAGTGTTTGAAGCCAAGGTGCACATCCATTGAAGACATTTTACTTTTAATCTAATCCGATCAGCAATAAGAACGATATGTGAAATTAATTTTAGTCTCTGCCTGCTCTAAAGCTTTACTAAGATGTCAGACGGTCGCTCTCTTAGACTTCCCTCTCGCCACATGCCCATTGATATCTTTACACTCCCACTAAACTCTCATGCATGAAATATTTTCCCTGTTGTAAAATGTGAAACCTGAGCACCCCAACCCTACAGTCCAGCTACTTGCTTAAGCTCTTGAGTGCACCTCTGTAACTGATATTTCAGATACAGCTGAAATGTTGTTAGTTTTGCATCATCAGCCCAGAGTTCTGGCGATTCTGCTTTATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13542
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000098300 Essential Splice Site 696 884 8 9
Genomic Location (Zv9):
Chromosome 5 (position 31797946)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 29558776
GRCz11 5 30158929
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGTGATGGTACAACCTGCAGGAAAATAAGTGGTTCGCTAAACAAAGCTAC[G/T]TAAGTGAAAATCATATTTTTAAGCAATTCATTTAAAAAAAAWNKAAATATA
Long Flanking Sequence:
CCCACTAAACTCTCATGCATGAAATATTTTCCCTGTTGTAAAATGTGAAACCTGAGCACCCCAACCCTACAGTCCAGCTACTTGCTTAAGCTCTTGAGTGCACCTCTGTAACTGATATTTCAGATACAGCTGAAATGTTGTTAGTTTTGCATCATCAGCCCAGAGTTCTGGCGATTCTGCTTTATGTGGAATAGCCATTATGTGAGAACAGAATACACTGGAGCACTTAGGCTGCCATTGCAATAAAAATACACATTATTTCTTGAAACATTTGTTGAAGGTTTCTGTCTATTCTGACACTCGTCTTTTCTATATGCTGGGCAGGTTGTGGATGGCACCACCTGTGGGCCAGATACCACATCCATCTGTGTTCAGGGCCAGTGCATCAAAGCCGGATGTGACCAGGTGATAGGTTCCAATGAAAAGCTGGACAAGTGCAGTGTTTGTGGAGGTGATGGTACAACCTGCAGGAAAATAAGTGGTTCGCTAAACAAAGCTAC[G/T]TAAGTGAAAATCATATTTTTAAGCAATTCATTTAAAAAAAAAGAAATATAAACACTGGGAAAGGCGAGAGCTGCTGATATAACTGATATGAAATTCTGATTTTAGGCATCAGGGTACCATATTTCAGTGTGAGAAATGGCTATTCACTTTGAGATTTGCTAAAAAATTAGTTTTGTTAGTAGTTTTAAAGATTAACTTTGGTAAGTGTTTAAGGAAAAATGTAAATGTTGATGATGGGCTTAAGCAATTAATGACCCACTATGAGTTAATATCTGTTAATACATCCAATATTCAGAATTGTGTTCTGGAAGAACCATTTGTATGGGGCCCACCATCATAAAATCATCAGTGAAAAGTTCTTAAAAGGATTGATCACTCAAAATTCAAATTTAATGTTAATAAACTCACCCTCAGGCCATGCAAGATGGAGACAGTTTGTTTTCTTCAGGAGAGCCTTCAAGAAGAGCTTGAGCTAAAACTGTGGTCCTTTCAGAGAGTGT
Associated Phenotype:
Not determined