Busch Lab

ZMP

mat2a

Ensembl ID:
ENSDARG00000040334
ZFIN ID:
ZDB-GENE-030131-2049
Description:
methionine adenosyltransferase II, alpha [Source:RefSeq peptide;Acc:NP_997802]
Human Orthologue:
MAT2A
Human Description:
methionine adenosyltransferase II, alpha [Source:HGNC Symbol;Acc:6904]
Mouse Orthologue:
Mat2a
Mouse Description:
methionine adenosyltransferase II, alpha Gene [Source:MGI Symbol;Acc:MGI:2443731]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa14309 Nonsense Available for shipment Available now
sa16647 Essential Splice Site Available for shipment Available now
sa34836 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa14309
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112201 Nonsense 4 309 1 8
ENSDART00000121531 Nonsense 4 395 1 9

The following transcripts of ENSDARG00000040334 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 6849894)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 7862694
GRCz11 10 7821394
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GATTAGAAACAGATTTAGAAGAGCGTAACAATACAATCAATATGAACGGA[C/T]AACTGAACGGCTTTCACAACTCYCTGATTGATGAAGACTGYTTTTTGTTC
Long Flanking Sequence:
GTTACACTGTCTATCATCTGGACTAACGTTGTTTAGACGCCTATATTAGACATCTTTAAAAAAAATGCTTTCAACAAAGTAATCCCAGTCTTTTTTTATATGTGCGGTTTTATTTTCGCTTTTTTATTTAGTAAATTTCTCAGAAATTCCTATCTAAATGTATACATTTAACGCAGTATATATAAGCTGGGCCTTCTTTGTCTCCTCCTTGCCGTTGTAGGGCCCTGGCGTCCTTTCTTATTGGCTTAATGGAAGACGGACGGGGGCGCGCCCGAGTGACGCTTGAGTTTGGAGTGAAGTAGGAGGGATAAAACCTTGAAGACCGGCTGGCGTGAGCATTTGAGGTCAAGTCTACGCAGCGTGTTCGAGACAGAGAAACATCAGAAACATCTATTTAACACCGACGTTAGAAAAGCAGAAACTGACACGCTAGACCGGCGAAACAAACCCGATTAGAAACAGATTTAGAAGAGCGTAACAATACAATCAATATGAACGGA[C/T]AACTGAACGGCTTTCACAACTCTCTGATTGATGAAGACTGCTTTTTGTTCACGTCGGAGTCTGTCGGCGAAGGACACCCTGGTATGTATCATAACACATATATTTAAAGGTTTTTTTTTTATTTTACAAGGTCGCGCGGGAGGTAAACACGATCAGGCACGAGAGCCATTGGCTAACACGTGCTAATAACTGCTGATCTGTATTATTTTTTTTTTGTGTAAATGCGCAGAATTTTCTTATTCTTGCAGTTGATTTAATCCGCGTTTTTAGATGTACGTAAAATGTGGTGTTTGTAAATATATGGTTGGTTAATCTGTGTTTGTAATCCCAGGCCACGCGCGGCGGCCTCGTCGTGTTTGAAGCCCAAAGCGTCATAAAATTATAGATCGTGAATGCATTAAATGGGCCATTTATAATTTTAGTATGTTTTTTATATAACAGAATGGGTAAAATAAGTATTAGACGCGCTATAGTGGCTCCTTGTGACCATTTCCGTTTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16647
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112201 Essential Splice Site 30 309 1 8
ENSDART00000121531 Essential Splice Site 30 395 1 9

The following transcripts of ENSDARG00000040334 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 6849812)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 7862612
GRCz11 10 7821312
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGAAGACTGYTTTTTGTTCACGTCGGAGTCTGTCGGCGAAGGACAYCCTG[G/A]TATGTATCATAACACANNNTATATTTAAAGGTTTTTTTTNNATTTTACAAGGT
Long Flanking Sequence:
TCCCAGTCTTTTTTTATATGTGCGGTTTTATTTTCGCTTTTTTATTTAGTAAATTTCTCAGAAATTCCTATCTAAATGTATACATTTAACGCAGTATATATAAGCTGGGCCTTCTTTGTCTCCTCCTTGCCGTTGTAGGGCCCTGGCGTCCTTTCTTATTGGCTTAATGGAAGACGGACGGGGGCGCGCCCGAGTGACGCTTGAGTTTGGAGTGAAGTAGGAGGGATAAAACCTTGAAGACCGGCTGGCGTGAGCATTTGAGGTCAAGTCTACGCAGCGTGTTCGAGACAGAGAAACATCAGAAACATCTATTTAACACCGACGTTAGAAAAGCAGAAACTGACACGCTAGACCGGCGAAACAAACCCGATTAGAAACAGATTTAGAAGAGCGTAACAATACAATCAATATGAACGGACAACTGAACGGCTTTCACAACTCTCTGATTGATGAAGACTGCTTTTTGTTCACGTCGGAGTCTGTCGGCGAAGGACACCCTG[G/A]TATGTATCATAACACATATATTTAAAGGTTTTTTTTTTATTTTACAAGGTCGCGCGGGAGGTAAACACGATCAGGCACGAGAGCCATTGGCTAACACGTGCTAATAACTGCTGATCTGTATTATTTTTTTTTTGTGTAAATGCGCAGAATTTTCTTATTCTTGCAGTTGATTTAATCCGCGTTTTTAGATGTACGTAAAATGTGGTGTTTGTAAATATATGGTTGGTTAATCTGTGTTTGTAATCCCAGGCCACGCGCGGCGGCCTCGTCGTGTTTGAAGCCCAAAGCGTCATAAAATTATAGATCGTGAATGCATTAAATGGGCCATTTATAATTTTAGTATGTTTTTTATATAACAGAATGGGTAAAATAAGTATTAGACGCGCTATAGTGGCTCCTTGTGACCATTTCCGTTTGAAGCCTGTGCGCGCGCGTGGTGGCCATGTTGTCGGCGGGCTCGCGGAACATGTGTTCTTGTGCAATGCGGACCCGCGCAATAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34836
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112201 Nonsense 48 309 2 8
ENSDART00000121531 Nonsense 48 395 2 9

The following transcripts of ENSDARG00000040334 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 6843821)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 7856621
GRCz11 10 7815321
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAAGATTTGTGACCAGATCAGTGACGCTGTGTTGGACGCCCACCTCAAA[C/T]AGGATCCTGATGCCAAAGTAGCATGTGGTGAGTGTCAAATTATGCTTTTT
Long Flanking Sequence:
TGTTAAGAGTCTTTTTATTGATCATAAGCCAGCCCTAAAATAATCATCTTATCTTGAACAAATTTCCACTGTCTTTCGGGCCGCTGCTTTGCTCATGTCAGTAAGATTTCATCTTTAAATTACAATTTTCTGTGATTGAGTCATTAGTATTTTTTTCTGTAGTATTGTACATTTTGTACATATGTTTTTGCTGTCAGTCTAAAATTCAAAATCTGCTAAAGCACAACCGTGGTGTGCAAATGAAAGAAAAATTACATTCATTCATTACACACAGTCTTGTAAGTGATTTATTAATGAGGATAAAGCACCTCAAATTACCAGAGAGCAGCAATATATAGATGTCATGGGACCCCCAAGTTATTTGGTAAATCTCTGGCAGTTAGCTGTTGCTTAATTTAACCTGTTTGTATGAGCTAATTGAAACATTCCGTACCCTTTCTTCTGTTCCAGACAAGATTTGTGACCAGATCAGTGACGCTGTGTTGGACGCCCACCTCAAA[C/T]AGGATCCTGATGCCAAAGTAGCATGTGGTGAGTGTCAAATTATGCTTTTTCTGCACTTTTTTTACTCCATGGTGCAAATAGAGTCTTCACTGTGTCTTAACCTTTATCAATCAATCCTGACAGAGACTGTCGCCAAGACTGGAATGATCTTGCTGGCCGGAGAGATCACTTCTCATGCTGTAGTGGACTATCAGAAGGTAGTCAGGGACACCATCAAGCACATTGGCTATGATGACTCTTCTAAAGGTAAAACACCAAGAAACATTAGGGGTGCTATTAAGTTATGGTTACATGACATTGGTAGCCAACAATGGAAATTTTTCTCTTTGCATATTTAAAGTTTCACATTTGCATGACATTTTGTGGGGGAAAAAAGCCCAAAACTTTATTTTACCAATGCCAGGTCATAATTTGACACTGTCATCTTGTTAGTAAATAGTACTTGTAGAGAAGTCATGACAGTCGTTCAGTAGTTTTTGTAATATGCTGTATAAGATGTC
Associated Phenotype:
Not determined