ZMP

si:dkey-14d8.5

Ensembl ID:

ENSDARG00000006409

ZFIN ID:

ZDB-GENE-041210-123

Description:

mitogen-activated protein kinase 12 [Source:RefSeq peptide;Acc:NP_001038306]

Human Orthologue:

MAPK12

Human Description:

mitogen-activated protein kinase 12 [Source:HGNC Symbol;Acc:6874]

Mouse Orthologue:

Mapk12

Mouse Description:

mitogen-activated protein kinase 12 Gene [Source:MGI Symbol;Acc:MGI:1353438]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa40217	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa14265	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa40217

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000027304	Essential Splice Site	229	364	9	12

Genomic Location (Zv9):

Chromosome 4 (position 5401940)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	5520121
GRCz11	4	5528691

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GCAGACAATCGGCTCTCTTTTCCCCCAATAAATCCTTAACTTAGACTTAC[A/T]GACCTAGACCAGCTGAGAGAGATCATGAAAATCACAGGAACTCCAGCTCC

Long Flanking Sequence:

GGGTTATGTGGTGACCCGCTGGTACAGAGCACCAGAGGTTATCCTCAACTGGATGCACTACTCACAAACAGGTGACATACAGAACTACCAATACCGTACAGATAAACGTAGCTATGAAATCAGCTAACCACTAAAAGTCACTGCAGGACATCTCAATGAGAATGATTTTTTTGTTTTTGTTTGTTTCAGTTGATATCTGGTCAGTGGGCTGCATCATGGCGGAGATGTTACTTGGAAGGACACTTTTTAAAGGCAATGACCGTATCTTTTTTCTTCATGCAACTACTGCTTATTACAGGCTCTAAAGATTTCAATCATAAGATTGAAAAGTACCGTAAATGTTGTGTGCGGTATGAACATGCATCACAGAAGCTGCCACTGCACATTACTCCATTTACAAGTAAAAACCTACTGCTCTTTATTCAAAGATTACCACAGTCAATAGAGACTGCAGACAATCGGCTCTCTTTTCCCCCAATAAATCCTTAACTTAGACTTAC[A/T]GACCTAGACCAGCTGAGAGAGATCATGAAAATCACAGGAACTCCAGCTCCGGATTTCATCACCAAGCTACAAAGCCAAGATGTGAGTGTGTCACACATAAAAAGAAAGATTAATTCATTACATTTTCACCCATGCATACACACAACTGATTTCTTCATCCATTCATACAGGCCAAAAACTACATCAGAGGTCTACCTAAAGTCCCAAAGAAAGACTTAAACACTATTTTCTTCAAAGCCAGCTCAGAAGGTAAACTACTTCTTTCTTTTGCAACATTGTTAAGGTCAGATAGAAGTTGTTGATGATTCCATCCACCATTTCTTCAGATTGATGGATGGAAACATACAGTTGCTAACGTCTAATGTGTCTGTGTGTATGTTTTTTTTTTGTTAGCGGTGAGTGCTCTGGAGCTAATGCTGGTTCTGGATCCAGATAAACGTGTAAGCGCTGCAGAGGCGCTCGAACTTCCCCTTTTTACAGAGTTCAGAGAACCTGAAGAA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa14265

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000027304	Nonsense	250	364	9	12

Genomic Location (Zv9):

Chromosome 4 (position 5402004)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	5520185
GRCz11	4	5528755

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TGAGAGAGATCATGAAAATCACAGGAACTCCAGCTCCGGATTTYATCRCC[A/T]AGCTACAAAGCCAAGATGTGAGTGTGTCACACATAAAAAGAAAGATTART

Long Flanking Sequence:

CAAACAGGTGACATACAGAACTACCAATACCGTACAGATAAACGTAGCTATGAAATCAGCTAACCACTAAAAGTCACTGCAGGACATCTCAATGAGAATGATTTTTTTGTTTTTGTTTGTTTCAGTTGATATCTGGTCAGTGGGCTGCATCATGGCGGAGATGTTACTTGGAAGGACACTTTTTAAAGGCAATGACCGTATCTTTTTTCTTCATGCAACTACTGCTTATTACAGGCTCTAAAGATTTCAATCATAAGATTGAAAAGTACCGTAAATGTTGTGTGCGGTATGAACATGCATCACAGAAGCTGCCACTGCACATTACTCCATTTACAAGTAAAAACCTACTGCTCTTTATTCAAAGATTACCACAGTCAATAGAGACTGCAGACAATCGGCTCTCTTTTCCCCCAATAAATCCTTAACTTAGACTTACAGACCTAGACCAGCTGAGAGAGATCATGAAAATCACAGGAACTCCAGCTCCGGATTTCATCACC[A/T]AGCTACAAAGCCAAGATGTGAGTGTGTCACACATAAAAAGAAAGATTAATTCATTACATTTTCACCCATGCATACACACAACTGATTTCTTCATCCATTCATACAGGCCAAAAACTACATCAGAGGTCTACCTAAAGTCCCAAAGAAAGACTTAAACACTATTTTCTTCAAAGCCAGCTCAGAAGGTAAACTACTTCTTTCTTTTGCAACATTGTTAAGGTCAGATAGAAGTTGTTGATGATTCCATCCACCATTTCTTCAGATTGATGGATGGAAACATACAGTTGCTAACGTCTAATGTGTCTGTGTGTATGTTTTTTTTTTGTTAGCGGTGAGTGCTCTGGAGCTAATGCTGGTTCTGGATCCAGATAAACGTGTAAGCGCTGCAGAGGCGCTCGAACTTCCCCTTTTTACAGAGTTCAGAGAACCTGAAGAAGAGACGGAGGCCCTGCCTTATGACCACTCCATGGACAACACAGAACTGCCTCTGGATCAGTGGA

Associated Phenotype:

Not determined