Busch Lab

ZMP

ints1

Ensembl ID:
ENSDARG00000059631
ZFIN ID:
ZDB-GENE-030131-6523
Human Orthologue:
INTS1
Human Description:
integrator complex subunit 1 [Source:HGNC Symbol;Acc:24555]
Mouse Orthologue:
Ints1
Mouse Description:
integrator complex subunit 1 Gene [Source:MGI Symbol;Acc:MGI:1915760]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa20113 Nonsense Available for shipment Available now
sa18206 Nonsense Available for shipment Available now
sa40146 Nonsense Mutation detected in F1 DNA Not yet available
sa14215 Nonsense Available for shipment Available now
sa20112 Essential Splice Site Available for shipment Available now
sa40145 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa20113
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083062 Nonsense 528 2194 10 47
Genomic Location (Zv9):
Chromosome 3 (position 43604041)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 42305439
GRCz11 3 43011454
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCAGTCCTTCTGTTTAGGCCTCATGCAGGAGAGGAAAGAGGCCACTTA[T/A]GTGGACATGGAGTTTAAAGTGAGCACTGGATTGCTGCATTTGTGTGTTTT
Long Flanking Sequence:
CTTAGGAAAGTTTAACTAGCTTTGTTTCCATCCATGTATTTTTATATTCATGTCGTGATGTTGCATTAACATGCAGGATGGAAGATGTTAGGTGGGCCTCTGATATTAACTTTGTCCCACTTGCCAATAAAATTTATTATATTTTTTTTCTCTTGAACACACTTAATAGATGTGCTTTGTTTACAAAATATTAATGCAAAGATAAAATGTCAACTTTTACTAAATAAAAAGTTATCATATGTTAGTTTTGCTCATACTTATTAAAAAAAACTCTTGACCCTGAGTATCAGACTTTAAATGTTGCAGTTTTTTACAATTTTTTGTTTTCTCGTTTGTCTCTAGTTTCTTGCCATGGTCTTCCAGGACCTGCTGACCAATAAGGATGACTACTTGCGGGCCTCGAGGGCCTTGCTCAGGGAAATCATTAAACAGACCAAACATGAGATCAACTTCCAGTCCTTCTGTTTAGGCCTCATGCAGGAGAGGAAAGAGGCCACTTA[T/A]GTGGACATGGAGTTTAAAGTGAGCACTGGATTGCTGCATTTGTGTGTTTTAAGAATATCAGTTTTGCATGTATATAATTTGTTTTTGGTTTCCATTTTAGGAGCGTTTTGTCATCCAAGTGACGGATCTCTTGACCGTGTCCATGATGCTGGGGATTACAGCTCAGGTCAAAGAGGCCGGGATTGCCTGGGACAAAGGGGAAAAGAAGAGTAATACTGTTTTATACTGTTAGTGACACAAATATCCAACATTCAAATGTGTAGTATTGATCTTAATGATTATGTGTATGTATTTCAGATCTAGAGGTACTGAGGTCCTTTCAGAACCAGATCGCTGCTATTCAGAGAGATGCTGTGTGGTGGCTGCACTCTGTTGTTCCCACCATCAGTAAAGTGGGACCCAAAGACTACGTGCACTGGTATGGTTCAGAGGATTGCAGGATTTGTGCTGTTAAATAATGTTAGTAAAATGGTTATTGGTACTTAAAATAAAGCAGAAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18206
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083062 Nonsense 624 2194 13 47
Genomic Location (Zv9):
Chromosome 3 (position 43601337)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 42308143
GRCz11 3 43014158
KASP Assay ID:
2259-3977.1 (used for ordering genotyping assays)
KASP Sequence:
NNTTTTCAACAGCCTCCACAAGGTGCTTTTCACCGAGCAGCCTGARACGTA[T/A]TATAAATGGGAMAACTGGCCTCCTGAGAGTGACAGAAAGTGAGTTACCTC
Long Flanking Sequence:
AAATGTCTTAAATTTCAAAAACAAAAAGCCTTCAATTCACATAAATATTGGGCTGTAGGTCTTAAATAATTTTTAACAGGTCTTAATTTTTCTATGTCCATGTAAAGCTACGCAATGGGGCTAAGTTCATCTCAATTAAAGTTTTAACAGAAGATTATTTATTTACTATATTTACCAATGTGGTTTAATTATCTTCATTACAATAACATTTGTTTTAAACATTTTTTTAATGTTTTAACTGAACCAGTAGAAAAAATCTTTTGCGTTTACTCTTGTGTAAGTCTAAAATTTATTTCATAATGTTTTTAAAAGGTCTTAAAAAGTCTTAAATTTGACTTGATGATACCAGTAGAAACCCTGTGTTCAACTGCAACAAGGACACCTCAAAATAGTGTAACTTTTTCAATGTTATCAATGACACCCGTGCAGTATACTGATTGTTTTGTTGTGTTTTTCAACAGCCTCCACAAGGTGCTTTTCACCGAGCAGCCTGAAACGTA[T/A]TATAAATGGGACAACTGGCCTCCTGAGAGTGACAGAAAGTGAGTTACCTCTATTTTAGCATCTTGCAGATGTTTTCAGCATCTGTCTAATAAATGCTAATCTATCTCTCTTCTGTGTTAGTTTCTTTCTTCGGCTGTGCTCTGAGGTTCCTCTGCTGGAGGACACATTGATGCGCATCTTGGTGATTGGTCTGTCCCGTGATCTGCCCCTGGGCCCAGCTGATGCCATGGAGCTGGCTGATCACCTGGTGAAGAGAGCTGCAGGAGTTCAGTCTGATGGTAAGACAGCACTTCTGGTTACAGAGATGGTTTTCCTTATTTTAGAGTGGCCATGTGATGCTTTTTTGAAAAGGTCATTATTTAGTTTGTTGCATGTACCAATGTTATTTAGTAAAGGAAAACTATTTTAATTAATAAAATCAAATCAAAATTTCACAATAAAAGAAAAACTAAAACAAGATAAATTGAAATAAAATGATAATTAGCATAAAAGTTTTCAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40146
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083062 Nonsense 625 2194 13 47
Genomic Location (Zv9):
Chromosome 3 (position 43601334)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 42308146
GRCz11 3 43014161
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCAACAGCCTCCACAAGGTGCTTTTCACCGAGCAGCCTGAAACGTATTA[T/A]AAATGGGACAACTGGCCTCCTGAGAGTGACAGAAAGTGAGTTACCTCTAT
Long Flanking Sequence:
TGTCTTAAATTTCAAAAACAAAAAGCCTTCAATTCACATAAATATTGGGCTGTAGGTCTTAAATAATTTTTAACAGGTCTTAATTTTTCTATGTCCATGTAAAGCTACGCAATGGGGCTAAGTTCATCTCAATTAAAGTTTTAACAGAAGATTATTTATTTACTATATTTACCAATGTGGTTTAATTATCTTCATTACAATAACATTTGTTTTAAACATTTTTTTAATGTTTTAACTGAACCAGTAGAAAAAATCTTTTGCGTTTACTCTTGTGTAAGTCTAAAATTTATTTCATAATGTTTTTAAAAGGTCTTAAAAAGTCTTAAATTTGACTTGATGATACCAGTAGAAACCCTGTGTTCAACTGCAACAAGGACACCTCAAAATAGTGTAACTTTTTCAATGTTATCAATGACACCCGTGCAGTATACTGATTGTTTTGTTGTGTTTTTCAACAGCCTCCACAAGGTGCTTTTCACCGAGCAGCCTGAAACGTATTA[T/A]AAATGGGACAACTGGCCTCCTGAGAGTGACAGAAAGTGAGTTACCTCTATTTTAGCATCTTGCAGATGTTTTCAGCATCTGTCTAATAAATGCTAATCTATCTCTCTTCTGTGTTAGTTTCTTTCTTCGGCTGTGCTCTGAGGTTCCTCTGCTGGAGGACACATTGATGCGCATCTTGGTGATTGGTCTGTCCCGTGATCTGCCCCTGGGCCCAGCTGATGCCATGGAGCTGGCTGATCACCTGGTGAAGAGAGCTGCAGGAGTTCAGTCTGATGGTAAGACAGCACTTCTGGTTACAGAGATGGTTTTCCTTATTTTAGAGTGGCCATGTGATGCTTTTTTGAAAAGGTCATTATTTAGTTTGTTGCATGTACCAATGTTATTTAGTAAAGGAAAACTATTTTAATTAATAAAATCAAATCAAAATTTCACAATAAAAGAAAAACTAAAACAAGATAAATTGAAATAAAATGATAATTAGCATAAAAGTTTTCAGAGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14215
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083062 Nonsense 1284 2194 28 47
Genomic Location (Zv9):
Chromosome 3 (position 43588675)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 42320805
GRCz11 3 43026820
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAGTGTGCMAAAAGATACTAGCATTATGTGTGTTATTGCCTGTTAGATTA[T/A]ATGGCTCATCTGGTGGAGGTCCAGCATGAGAGAGGAGCCACAGGAGGACA
Long Flanking Sequence:
TGTTTTCCTGGTCATTGCGCCTTTGCCATGTGCTGTGTATATGCAGACGATCGGATACGAGTCACTTTTAAAAGATGATGTAAGCAGGTCATCAAAAAAATCAAATACAGTCACAAAACCGGAATTGATCATCAAGATCTGCAGTGTAAATGCAGCCATATTGTCAGCCATCATAAGATATCATTAAAACAACAGGTACACTGTGATCTTAGATGATAAATAACTCACCCTTCTAGTGTCCATCTGATTTTCTCTGTCATTTTCAGCTCTGCAAGATCTGGAGCCCCAACAGCTACTGTTGTTTGTCCAGTCTTTCGGGATCCCCGTCTCCAGCATGAGCAAACTGCTGCAGTATCTGGACCAGGCCGTGTCTCATGATCCCCAAACACTGGAGCAAAACATCATGGACAAGAGTGAGGCTCTTTCAGTTGTCTTTTTTTCTCCATTATTGAGTGTGCCAAAAGATACTAGCATTATGTGTGTTATTGCCTGTTAGATTA[T/A]ATGGCTCATCTGGTGGAGGTCCAGCATGAGAGAGGAGCCACAGGAGGACACACGTTCCACACTTTGCTCAGCGCTTCACTTCCTCAACGTAGAGGTCAGGATTTATTGCTTTACGCCATGGGTTGAGTCAGCAATGATTAATGGTGCTGTTTTACTGCACGGCGTGATTAAATTCTCTACTAATGAATCCTCTGCTGGTCTTGTGTGTTACAGACAGCTCAGAGGTGAGCAGGGCTAAAGTGACTGTTGAAACACCCCATGGCTCTGTGAAGATGAGAGCAGTGAGTCAGGTGCCAGTAATCGGCCCAGAGGATGATCTTGCTGGGGTCCTACTACAGGTACGACATTTTATTCTTGGCCTTAGTCTTTTAGGTTTGAGCAGGGTGCAGCCATTGGACCCTTATTGGCTTGAGACTTTAAGTTTCATCCACTTGTATTGGTTTTTACCTCTGAGAAATAGCTTGTTATGCTACTTCATGTTGCAAACTGGTATTTTCTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20112
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083062 Essential Splice Site 1540 2194 32 47
Genomic Location (Zv9):
Chromosome 3 (position 43583394)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 42326086
GRCz11 3 43032101
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGAGAGCTGGAGAAAAGTGCAATGCTGAACCTGAACTCATCAGAAAAGG[T/C]ATTTTAGTGGGATTTTTTTCACCAGGAAATATAGTTTTGACTACTTACAG
Long Flanking Sequence:
TCTATTGTTGTTTGCTTTTGCTTACTCTCTACTTCTGTTTTTCTCAATCAGAGGTCGGTTTCTCAGGACGTTGGCTTCTCGTCACTGTTCTTTAACGCCGTAGTGCAAATGTTGACGTGGTTGGAGAACTCGGCGGTAGACACGGGTCCTCTCCACAGCCTCCTGAAGTCTCTGGCAGCGCAGTACTCTCACAAACATCGCATCACAGATGGTGAGCAGCTCCCGATCCTGATTCTTAGCCATACAGATCACTTTTACTAGCGTGTAATCCAAATGACGACAGAGAAATAGGGAAAACATGTGAAATAAATGCAGTCAGCAGAATATATGCTCTGCTAGTGTGTTTGATTCTGTCTTGTGTCATCAGTTCGTACAGGATTTCTGCATTTGGCTGAAGCGCTAGCTTACAGACGGGACTCTGAAGTGGCAGTGAGGGGCATTATTGCTTCTCTGAGAGCTGGAGAAAAGTGCAATGCTGAACCTGAACTCATCAGAAAAGG[T/C]ATTTTAGTGGGATTTTTTTCACCAGGAAATATAGTTTTGACTACTTACAGCAAGGGTGTCAAACTCAAATTTGGGCCATTTTCGTGACTGACAACTCAGAGGAGGCATATTTACCATTCAAGCACAAGAAAAAAGTGGTAACCTGATGTAATTGATGCGTCTTAGGAGAACAGACATGACGTTTAAAATTCAAGCGTCACCTGTTACCAGTGATAATGCAAATCAGCATGTTTGTGGAATCACACACATAAAGTTGTTTGTACCTGGCATGGAGATACAATTAGATTGTAGTTTAAACACTTGTGGTTGAATGCATTTAAGAAACCATTATAGACTACCTACACTCTACGTACTGGCCTAACATGTAATCCTTCTGGCTTCTGAGAAAGTGCACCTAAACAAGTTGTTCGTTCTAAATAAATTTAAAATAAATTAAAATTTTCTAAATTAAATAAACACAGGGAATTTAATTAAATTATATTTTAATTTATTTTATTTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40145
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083062 Essential Splice Site 1797 2194 38 47
Genomic Location (Zv9):
Chromosome 3 (position 43567031)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 42342449
GRCz11 3 43048464
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTTTTTATTGGCAGTTTAAGTAGTTATTTATTGTTTGTGTGCTGTTTAC[A/G]GTATAATGAGTAAGAAGTGTCAGACGCTGCTGCTTCAGATCTATCTGCAC
Long Flanking Sequence:
TTCATATATCTTACTGCTTGTTTTAAAGGACAAAATTGTATTGCAAATAATATATAAATATATTTATCTATTTTAACACAAGAATTCCTGTGCTGTAAAATAAAATATTATATTGTGTATAAAAAACATCGTCAATGCACCGTGATGCTCTGAGATATCGAATTGAACCGAATTGATGGCATGATAATCACAACCAAACTAAACAGTTAGACCAGTGTCTATATAGTTCATAAACTGTTTATTTATTTATTTATTGATGCTTTAAAACTAATTTGTTACACCACTAGACCCACTAATGTGACCTGGTGAATCCAAAAGTGGGTTTAAAAAAAATCTGCAATAAAATGTTAACCAGTCGCTGCGTTGTACATGTTCCTCATATTTTTAACCTAAACTCCTGATGCTGATTTAATATAAAAAGATTTAGAGAATCAGAACAGGCTCTTCTTAGCTTTTTATTGGCAGTTTAAGTAGTTATTTATTGTTTGTGTGCTGTTTAC[A/G]GTATAATGAGTAAGAAGTGTCAGACGCTGCTGCTTCAGATCTATCTGCACTTCCCGGAGGTCATCCAACACATCCGCCTACCAGAGGCCACACTGAGCGGCGAGGGGGCAGCAGACGGCAGCACATGCAAGGTACCGGCTGCAGAGACTGACACCTCCTGTTAATAGCACTGCACAGATTATTAATACTCTGCTTGTTTTCTTTCTCTCTCTATGTGTGTGTGTATCCGCATATTCAGTTGGACGTCCTCGTGCATCGGCTCATCACTCTGCTGGCTGACACTGGAGACTCCAAATCAGCTGAAAACCGTGTGTCTGATGCCAATCTGGCCTGCAGGAAACTGGCTGTCTCTCACCCGGTGCTCCTGCTCAGGTTTGCACAACACGCATCACAGCTTTCTGTTCCTTCCAACAAACTGTTGAATGTGTGGTTATGGGTTGTACTCATATGTGGGATTTATAATATATGAATAAACAGTAATGGCTTTCTATAGGTCATGT
Associated Phenotype:
Not determined