ZMP
zgc:152898
Ensembl ID:
ZFIN ID:
Description:
Two pore calcium channel protein 2 [Source:UniProtKB/Swiss-Prot;Acc:A0JMD4]
Human Orthologue:
TPCN2
Human Description:
two pore segment channel 2 [Source:HGNC Symbol;Acc:20820]
Mouse Orthologue:
Tpcn2
Mouse Description:
two pore segment channel 2 Gene [Source:MGI Symbol;Acc:MGI:2385297]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa27083 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa16019 | Essential Splice Site | Available for shipment | Available now |
| sa14059 | Essential Splice Site | Available for shipment | Available now |
| sa34225 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa38652 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa27083
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000082690 | Essential Splice Site | 98 | 774 | 3 | 28 |
Genomic Location (Zv9):
Chromosome 7 (position 66333545)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 54749489 |
| GRCz11 | 7 | 55048829 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTGGGTCCTTACGATTGTATAGATGGTACTACTCCAACTTATGTCAGTG[G/A]TAAGCAAACAAAAAATTATGTTTTTTTTTGTTTTGTTCAAACTACTTCTT
Long Flanking Sequence:
AAATCAGATTTAGATTACAAAGCGTAGTTTTACTTTAGAATTAAGGGATTTAGAACCATTTAGCTAGATATTTATTATAATTTTTTTACATTCAAACACACTTTTTTTCTTTTTATTTACTTTTCTTTCACTTCTTCTTCTTCGTCTTCTTTTATTCTTTTTATTATTATTATTATTATTATTATTTATTTATTTATTTATTTTTATTTTTTTATTTTTTTATCTATTTTTTTTGCTAATGTGTTTCCTCTATGACAGATGCTGATGCAGACCTTTATGTCCAGCAGGCAGTAGTATTCATCGAAGATGCGATTAAGGTAAAAACACAATCAAAATAAAGACAGTTGTATACAAAATGTGTATATTAACTGTATATGTTGGTTTTTAAATAACTAATTGCTCTTTGTGTGCTCTTTTCTACAGTATCGATCCATTAACCACAGGGTGGATTCTGGGTCCTTACGATTGTATAGATGGTACTACTCCAACTTATGTCAGTG[G/A]TAAGCAAACAAAAAATTATGTTTTTTTTTGTTTTGTTCAAACTACTTCTTTAATGAGTATTAATTAAATATGACTAGATATTAAATATACGTGAGCTGAAACAACACAATTCTTGAGATTTTTTTGTGGACAACTTAATTGTTTTATGTTCAATCCACTTAAATTTGTCAGAGCTAATAAGTTAACTTAATTCCTTTATGTAGTCCCAACACAAATCGATTGTGCGAAACCCAGCATTTTTACAGTATATTTAGGGACAATGTTTTGCTAGAAAAAGAGAGAGAGAAAAGAAATAAAATTGTAAATTAAAACAGTAACTTCACATCGCTTCTTACATTATTTGAATTACATAAGTTATTTCACATTGGTTTTCATACTTAATAAAGCAAAACCCTGACCCCAGATCAAACCATTACTTTAAAAAACAAAGCCAAACTGTGTGCCCAGCATTTTTTATAGTATTTTTATGGACATTGTTTTGCTAGACAAACCAAGAAAGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16019
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000082690 | Essential Splice Site | 311 | 774 | 12 | 28 |
Genomic Location (Zv9):
Chromosome 7 (position 66344744)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 54738290 |
| GRCz11 | 7 | 55037630 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTCTCTAAACCGAGGCTATTCTATATTTTTCATACTCTTTAGTGTGTTTG[G/A]TAAGTTGCATGGTGTTCAGGTCATTGTCACTRTATACACAACATGCCAAA
Long Flanking Sequence:
TTTTCCCTCACTGTATATTGCTGCAGTTGACTGATAAAATGTGTTTCTGTAGGACCCGAAGCAGAATGGAGAATGGCAGACATACTTCAGAAACCTTCCCAAAGCTCTTTCTTCTCTGCTAGTGCTGCTCACCACAGCTAATAACCCTGATGGTAAGTTTTCAGTTTCTCAGGAGGTGTAAATCTCTGAATGACTCAGTAAAGCTTTAGGTAGTCAGTGACACAAGATGACATTTTACCAGCGCTGTGTCAAATTCTCCGTCACTTCTGGCTCATTGCTGTAGAAGCTATGAGTCATTTAACCACATGACTTAAGGTCTTGTGACTTGTCACAATTTTTTGTTAAACTTTTACAGGTACCTGTATGTGTTTTAAATGTGAAACTACACCAGTGCTATAACTTTGTTTTGATCACTTTTTTTTTCCTCTCAACAGTCATGATTCCAGCATACTCTCTAAACCGAGGCTATTCTATATTTTTCATACTCTTTAGTGTGTTTG[G/A]TAAGTTGCATGGTGTTCAGGTCATTGTCACTGTATACACAACATGCCAAAAGATTGGAATAATTTATTATTATTTTATTTTATTTTTTTGCATTTATTTGATTTTCAAATATTGAATATAGTAGTCAACATTTAAAGCGGATTAAAAAAAGATTGAAAATTGTCCTAAGACAAGAATGGGTGTTTTCAATAGTTTTAGGCTATTTTCATTAACCTATTTTGATCCACTTCAAATGTTGACTATTTAATTTTAATAAATTTTTTAAAACATTTTTTCTTTTCTTCTCTTTTTAAATTTTATTTAATTTTAATTTACTTTATTTAATTAAATTTTTAATTAACTTATTTTTTTGTTTTTTTATTTATTATATTTTTTATTATATTCATTTATTTTTTTGTATTTAAATTTTTTTTACAGTTTTAAAATTTAATCTTTATTTTTAATTTAATTTAGTTTGATTTAAAATTTTAATTCATATTTGTATTTGTTTTCTATTTATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa14059
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000082690 | Essential Splice Site | 397 | 774 | 15 | 28 |
Genomic Location (Zv9):
Chromosome 7 (position 66350368)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 54732666 |
| GRCz11 | 7 | 55032006 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCATGGAGAGAGTCCACATGAARTCCTACTGCAGACAAGCTATCRTTAAG[G/A]TAAACACAGATCCTGGAATTGTTTGTTTAAATGTGTAGSYTAGATGTTTG
Long Flanking Sequence:
GAAAGCAAAGAAGGTCAAGGTGCTCCAGGATTGTCCAGCCTAGTCACCAGACATGGACATTATTGAGCATGTCTGGAGTAAGATGAAGCAGGAGGCATTGAAGATGATTCCAATGAATCTTGAAGAACTCTGGGAGTCCTGCAAGAATGCTTACTTTACCATTTCAGATGACTTTAATAATACGTTACATTGAGCAAGGACATTTTCAACTTTATTTTGAAACACTGTTATCCAACAACATGTACCTAATTAACGTCTTTTAATGGCACTTTAAGCTGAATATTAGTATCTTACAACATAAGCAGAAAAAAACATTATGCACTGTCACTATGACAAAGAAAAATAAATTAGTTATTAGAAATGAGTTATTAAAATAATTCCTATTTAATTAAAAGTGTGATAAATTGTTTCTGCTCAGGGAGCGTGTGGCGGTGAACATGTTTCTGAAGGTCATGGAGAGAGTCCACATGAAATCCTACTGCAGACAAGCTATCGTTAAG[G/A]TAAACACAGATCCTGGAATTGTTTGTTTAAATGTGTAGGCTAGATGTTTGTTTGATTGTCATTTGCATTCTCAGGCCGCTCGGCGGTTTCCAGATGGCTTCATCAGCGGCGAGGACTTCCAGAGGCTCTTCAATGAGCTGGACAAGGATTTTGTTAAAGAGGTTTTTCTGTTTATTTTTAGTAACCAACAGAATTAAGATTTACAAAAATCAATGTTTGTTTGGTAAAAGTAGTAGTGTGTGTCAAGCAAGGTTGAGCAAGAACTGGTTCCCATTTTAAGGTTTGGAATTTGAATCACAGGAAGAGGAATTAGCTGAATTGAAACTCCCAAAAGCTGTACATGGCTAGAAAATGAGGAACTTTTGTAATTCATCTACAAAGGACAAGAATAAATGACTGTTTGTAGGTTTTGTCTTATTTGCATGCTTCATTTTGGTTTACGACTTTGGATGATTATGAGATAATTCTGGAAAAGAATGTTTTGTAATAAATGTTAAATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34225
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000082690 | Nonsense | 705 | 774 | 26 | 28 |
Genomic Location (Zv9):
Chromosome 7 (position 66372519)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 54710515 |
| GRCz11 | 7 | 55009855 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCATGTCAGCTGGTCTCTGGTGTACTTTGTGGTCTGGTGGTTGACATCTT[C/A]AGTCATGTGGGTCAACCTGTTTGTGGCACTCATTTTAGAGGTATGTAGAT
Long Flanking Sequence:
ATAAACAGGGGGTCTAATAGTTCAGGGGGGCTAATAATTCTGACTGAATATTCAAGTGTACAGATATTTGTTAAACTAATTTCCATGACTAAACTAAAATCCATGTCAAAATTCCATAACTTTTCCAGGTCTTCCATGACCTTATAAACCCTGTTAATTTTTTTTCATTGATGTATTTCTGTTTGTTCTGCTTTAATCTATGTAACTTTCATAATGTAAATGATTGAACTGTTACAATTCTTTCCTCCCTGTCAATATTCCAGTCGTCTCTGATTCTGCTCTATAACATCATGGTGGTGAATAACTGGCATGTTTTCACAGACGCATATGCCAGATACACTACAGAGTAAGTCAGACGTCACACACACAGATGCCCCTCTGTCTTTCTTTAACACGTTTGATTGCTTTGGCTGTGATGGGTTTTTGTCAATTTGTACCTATCATTTTTTTCCATGTCAGCTGGTCTCTGGTGTACTTTGTGGTCTGGTGGTTGACATCTT[C/A]AGTCATGTGGGTCAACCTGTTTGTGGCACTCATTTTAGAGGTATGTAGATTGTTGACCAATTTACTTAAAAAAAATAAAGAGTTTTATTTGTTAAAGTTTTTGATATATGAAATATTAAGTTAAATATAGACCCAGTCAAGATTTAACAAATTCCCAGAATGCTATAGATAAGCATAGGCCTTAAGACCTAAGGGTTGTGCTTATTCTCTTAATGAGTTATGGGTGTGTTTTGAGCATAATGTGCATTAAACCAATCAGAGTCTCCTCTCCATTCCCTTTAAGAGTCAGTTGTGTCGCACATAATGCAACTAGAATAACTACAGTAGATGCGATCGTCTGATCTCATATGAAGCAAGAGATCACGATGACATATGATGCAGGTGTTGTAGTGGTGCCCTAATTCTTAACACCTGTGCACACCGAGATGTTTTTTGCTCACGTTTTCGGTTGACATTTAACGCCTCGTGACTAAATAAAGTGCATCAATGTGATCATGCAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa38652
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000082690 | Nonsense | 774 | 774 | 28 | 28 |
Genomic Location (Zv9):
Chromosome 7 (position 66377142)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 54705892 |
| GRCz11 | 7 | 55005232 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAGAGTTACTAGCTCAACTACATCAACATCCTCATCTCCACCTCTCCTG[G/A]TGACCCCCTCACCTCGGCCTTTAATACATAATTACACATACCCACAATCC
Long Flanking Sequence:
AGAGCAGCCCGTCTAACACCAACAACCATGCCACAATCAAAGTCACTTAAATCACCTTTCTTCCTCATTTTGATGCTCTGTTTGAACTGCAGCAGATCGTCTTGACCATGTCTACATGCCTAAATGCATTATTGAGTTGCTGCCATGTGATTGGCTGATTAGAAATTTGCATTAACAAGCAGTTGGACAGGTGCACTTAATAAAGTAGATATTAGTGCGTTTAATAGATTAAATGTTAAAACTTCTTGCCTTACACCAGGGTTTTCTAAATGTCAAAAATGTCTTCATGGAAGATGATGTTTACTTTAATATTCTAATGCTTTGTGGCATAAAAAAAAATGATTCATTTTAGTTTTTGGCTTTATTTAAGTTTAGTAAGAAATCTTCAATTTTAAGATTAATCCATTGTTGTTTTTGTCTTTCAGAGAGCACGTCAAAGAGCCGACAGAAGAAGAGTTACTAGCTCAACTACATCAACATCCTCATCTCCACCTCTCCTG[G/A]TGACCCCCTCACCTCGGCCTTTAATACATAATTACACATACCCACAATCCTCCAGGACTCCATCACGTCTGTGTAGGCCTCATGTTTACACATCCATCCATTTTGGAGAGCCTGTTTCCCATTACAGGATCTGTGTCGCTTCAGGTCGGTCTGGGAAAGGGTGTGTGTGTGTGTGTGTGTGTGTGCGTGTGTTTTCCAGCACAGTTAACGTTCAGAGGAACTTCAATTTATAATGTATAGTCTCTAGTTCTTGTTTTATCCTCAAGACAACCTGTTAATGAAGGTAGCATAAGTATGCATAAGTGGTTTTGATTTACCCCTTTTTTTGTCGTTTGATGATAATGGATTTATTTATTTTTTGTAAGTCTGTTACAGTCTGTAGATCTGTGGATTGTTTGAGAAATCATGGGTAAAAGGGACAATTAACGTGTACATTTTTTTAAAAGATGTGTTTTATTGATTTGTAGATTCAATATTTCTGACGTCCATTTTGTTTGTTC
Associated Phenotype:
Not determined