Busch Lab

ZMP

ENSDARG00000052664

Ensembl ID:
ENSDARG00000052664
Human Orthologues:
MSLN, MSLNL
Human Descriptions:
mesothelin [Source:HGNC Symbol;Acc:7371]
mesothelin-like [Source:HGNC Symbol;Acc:14170]
Mouse Orthologues:
Msln, Mslnl
Mouse Descriptions:
mesothelin Gene [Source:MGI Symbol;Acc:MGI:1888992]
mesothelin-like Gene [Source:MGI Symbol;Acc:MGI:3607710]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa33286 Splice Site, Nonsense Mutation detected in F1 DNA Not yet available
sa33287 Nonsense Mutation detected in F1 DNA Not yet available
sa33288 Essential Splice Site Available for shipment Available now
sa40142 Nonsense Mutation detected in F1 DNA Not yet available
sa1405 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa33286
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000074557 Splice Site, Nonsense 114 2048 3 48
Genomic Location (Zv9):
Chromosome 3 (position 42731466)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 43177539
GRCz11 3 43878456
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCATCAACATGACACTGAACCTGACCAGCACCAGTTCAGGGCTCCTCGAC[A/T]AGGTTAGATAGGAGTTTTTGACTGATAGATCCAATGATGAAACACCATAA
Long Flanking Sequence:
AAAAATATAGTATAATGGATGCTTCAATACCAATAAAGAAAATATTTTTTATGAGTGTACAGTTAAAATGCATGATTCAAGCTGTAAGTTTACTCTTTGTGTTGCTGATGTTGACTTTTTTGTTTTAAAGCTGGCTGTGTGAACAGCACAAACAGCACCGGGCAATGGCTGCTACTCAACTTCCAGTCATTCTCTTCTATTGCAAGCCTAGGAGATTTCATAGCTCTGAAACCAGACTTTAATGGGGTAAGTGAGCGAAACAGACCAGCTTTACATCCTAAATGAAATCACAGCATCACTGCTGAGACAATCCACATAAATGTTTGCAGCTGGTGGTCCTAGGTAAACTCACGCCGGAGCAGAAAGCTGAACTGATGTTTCAGCTAGAAGCCAACTTTAGCCTGAACGCTGATGCCGTCAGTCAGATCTTCCAGAGTTTCCTGCAGCCCCTCATCAACATGACACTGAACCTGACCAGCACCAGTTCAGGGCTCCTCGAC[A/T]AGGTTAGATAGGAGTTTTTGACTGATAGATCCAATGATGAAACACCATAAGGAAAAATCATCCAAATTGTTTTCATATTTCACTGCAGAATCTCACAGACTTTGTGCAATATTTGAGACCAATGGGAAGATTCATCAGATCATGTGTGAACATTGCTCAGACAGTAAGTTTTCTGTTCATATTTTGTGTGTAATAGTTAATTAATTAACCATAAATCTCTGCACACAACTGATAGATATGTGCCTAAGAAATTCAACTTGTGTAAGAATGTCAATTTTTGGAGTTTTAAAAGGGTACGGAGACCCAGAAGGGACGTGATGGTGGGGGAAAAATGGATGGGAGAAAAAAAAAGAGTGATAGGAAAATATATATATTTTTATAGTTTTCACGTTCTCTCTTAAATATGTTTTGCACTCTCTTGCAAAAAAGTTGTTCCACAAACACTTCCTGTTCACTTCATACATATCAGCCCTCCCGTTTTTGCCGGGATTCTCCCATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33287
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000074557 Nonsense 123 2048 4 48
Genomic Location (Zv9):
Chromosome 3 (position 42731580)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 43177425
GRCz11 3 43878342
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAATTGTTTTCATATTTCACTGCAGAATCTCACAGACTTTGTGCAATATT[T/A]GAGACCAATGGGAAGATTCATCAGATCATGTGTGAACATTGCTCAGACAG
Long Flanking Sequence:
CTTTTTTGTTTTAAAGCTGGCTGTGTGAACAGCACAAACAGCACCGGGCAATGGCTGCTACTCAACTTCCAGTCATTCTCTTCTATTGCAAGCCTAGGAGATTTCATAGCTCTGAAACCAGACTTTAATGGGGTAAGTGAGCGAAACAGACCAGCTTTACATCCTAAATGAAATCACAGCATCACTGCTGAGACAATCCACATAAATGTTTGCAGCTGGTGGTCCTAGGTAAACTCACGCCGGAGCAGAAAGCTGAACTGATGTTTCAGCTAGAAGCCAACTTTAGCCTGAACGCTGATGCCGTCAGTCAGATCTTCCAGAGTTTCCTGCAGCCCCTCATCAACATGACACTGAACCTGACCAGCACCAGTTCAGGGCTCCTCGACAAGGTTAGATAGGAGTTTTTGACTGATAGATCCAATGATGAAACACCATAAGGAAAAATCATCCAAATTGTTTTCATATTTCACTGCAGAATCTCACAGACTTTGTGCAATATT[T/A]GAGACCAATGGGAAGATTCATCAGATCATGTGTGAACATTGCTCAGACAGTAAGTTTTCTGTTCATATTTTGTGTGTAATAGTTAATTAATTAACCATAAATCTCTGCACACAACTGATAGATATGTGCCTAAGAAATTCAACTTGTGTAAGAATGTCAATTTTTGGAGTTTTAAAAGGGTACGGAGACCCAGAAGGGACGTGATGGTGGGGGAAAAATGGATGGGAGAAAAAAAAAGAGTGATAGGAAAATATATATATTTTTATAGTTTTCACGTTCTCTCTTAAATATGTTTTGCACTCTCTTGCAAAAAAGTTGTTCCACAAACACTTCCTGTTCACTTCATACATATCAGCCCTCCCGTTTTTGCCGGGATTCTCCCATATTTTACATTCTATGCTGTTATTATCCTATCATTATGTAATTTTCCATATTCCTCTCATATTTTTTAATCTTGAAAGCACATTGAAATTATTATAAAATGTCTAAATTCACTTTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33288
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000074557 Essential Splice Site 480 2048 11 48
Genomic Location (Zv9):
Chromosome 3 (position 42742179)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 43166826
GRCz11 3 43867743
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGACAAACTCAATAGCTTCCTACCAGCTCTTCAGACACAGGCCAGAAAA[G/A]TGTGTAACAGCAAACTGCTTCATATAATGGAGTCTCAGCAGGCAGAAACA
Long Flanking Sequence:
TTAATTGATTGTAAAATGTAAAATTAGCTTGTGCTCAGTAAATGTTTGCTCAATCTTTGAAGGACTCTATATTAATTACCTACAGTGGGGATCATATGTTGAGCAAATGTATTTATTTTGTAATTTCAGGTGTCGACTGCACATTAGCATATAACAACAGTGTGAACTTCATCCTGCAAAACTTCGGCAGTTTCTCTCAGTTTGCTCAGCTTCAGTTTTTTACCAATTTGAGCCTCAATTTTTCAGCTGTGAGTCTCACATTATTAGTGGATCACGTAAAGACACAACCTCAACACAACATAACACAACTCATGTCCTTTCAGGTGGAGGCTGTTCCTGTTCTCTCACTGACACAGCTGGGTGAACTGGTGTTCAGTCCTCCTGCTAGACCTGAAGACAGAGTCAACATCCTCACCAAAGTCTTTGACTTTCTTCTTCAAGCCTCTAACCGAGACAAACTCAATAGCTTCCTACCAGCTCTTCAGACACAGGCCAGAAAA[G/A]TGTGTAACAGCAAACTGCTTCATATAATGGAGTCTCAGCAGGCAGAAACACATCAAATATGCAAGTCGATTTCATCTCAATTGACTCCCTTGATGTCAAAATGACATCAAATTGTAAGATTGGTGTCAAAAATTGGTTACAGGACAGTCCTTTTTGACCTATTTGTTGACGCTAATGTTTTATGGATGTTCATTTTATGACATTTTGACATCAAGGTAGTTTATATGCAATTTAAGGATTCAAAATCCACTGTGAATTTATCACTTAAAAGGCTTTCAAAAGGATAAAAGATTTCTTATATTATAATACTCTTTGTGGGAGACACGGGGGCTCAGTGGTTAGCACTGTTGCCTCACAGCAAGAAGGTCGCAGTACTGTGTTGCAGCTGGAAGGGCATCCGCTGTGTAAAACATATGCTGGATAAATTGGCAGTTCATTCCACTGTGGCGACTCCTGATGAACAAAGGGACTAAGCCAAAGGAAAATGAATGAATAAAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40142
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000074557 Nonsense 873 2048 23 48
Genomic Location (Zv9):
Chromosome 3 (position 42748028)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 43160977
GRCz11 3 43861894
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTCTGATCTAAATACCGCTAATGGAGAAGTTCTGGTCTGGATTCAGACT[A/T]GACTCCCGCCTCTGTTATCCAACTTTTCAGAAAGCCTTGTGTCTCCATTT
Long Flanking Sequence:
CTGCTAATCTGACGGAGCTTTTGGCACTTGACAGTAACTTCAAAACAGTGAGTGTAAAATGATGCAGTTTACACAACCTTCTTGATTGAAAAAGCAATACTGTTTTTGACTTTTTCATCTTCTTGTTTATCCATTTAGGTGGAGGTTTTACCTGTTTTGAGTCTAAATCAACTGGTTGAGTTTTCCCTCACTCCTGGAGCTCTTGCAAATCCTCAAAGTGCTATCAAAGTCATGCAGCTTGTTAAGGATTGCCAGCTGCCCACCTTCTTTGACCGCTTTTCCCCCAAATTAAATGTAAAAACAGATCATTCTTGCTAAATATCCTAATTTAAAATATCTAAATAGACATTACTAAAGCTGCAGTGATATTATCTTCTTCTTTCCAGGACATCCTGCTCACGCCTGATGTAAAAACAGCACTGATTAAACAGATATTTGACAGAGCCAACCTGTCTGATCTAAATACCGCTAATGGAGAAGTTCTGGTCTGGATTCAGACT[A/T]GACTCCCGCCTCTGTTATCCAACTTTTCAGAAAGCCTTGTGTCTCCATTTTTTACCATCCTCAATGCAAGGGACTGCAATATCACTCAATTCGCGTAAGATCAATAGACTTTTTATCAGAATTAATGAGAGTAAACATTAAAACGATCTGAGAGCATAATATTGTGTGTTTAATTTGTCATTACAGACTGAAGCTGTTAGGGGGAGTTGGACCTTCAATACCCCCAAATACCAAAAATGCAATCTACAATAGCATTCTTCAGTCCTTTGGAGGTATTATGTTGACACAAACATCATCACGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATGTATGTGAGCTACATCACACTTGTAGCAGTGCGATGTGGCTTTATATCAGCACTAGTGGGAGGTGTGTGTTGGCACAAGGTCACAGGTCGAATGCCTTAGTGTCCCACCAGTGACGATATATAGCTACATCGCACTGCTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1405
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000074557 Nonsense 1568 2048 39 48
Genomic Location (Zv9):
Chromosome 3 (position 42762415)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 43146590
GRCz11 3 43847507
KASP Assay ID:
554-1326.1 (used for ordering genotyping assays)
KASP Sequence:
GGAACAAGCATCCGGAAACAGGATCTGAYAGTGCTGGGCAATTTGGTGTG[T/A]GTTGTGAGCAGTGACTACATTACAAACTCAGATCCAGAAATCCTGGAGAA
Long Flanking Sequence:
GAATTGAATTGAAATGGCTATCCACACCAGCAGATGGCAGTAGTATTATTTTTTAAATAGAAAATGTCAAAAATTGCAGACTTCACTGAATAGGATAATTATTTTGAATAAGGAATTACTTTGCAACTGCTTAAAAAGTTGCTCTTTGTATATGTGTAGTGTGAATGAAATCTGGAAGTACTACATTCACTATGTTGACAGTGTGAACTGATACTATCAGACATATCACTTTGATGCCATTCACAAATCTTCTCCTGTGCCTCATGGGCAGTAAAGTGTCCATATGATGCACACTTCAGGGAGGAATGAGTCTTTTTGTACATGAGTATTCTGACATTTCTGATATAAAATAGGGAAGTATGTGATCCTGGATGTAGCTTGGTGTGTCAAAGCTTTTAGATAATAAGTATCTAAATATACTCTTTTTTTTTTTCAATTAAGGCCATTAACGGAACAAGCATCCGGAAACAGGATCTGACAGTGCTGGGCAATTTGGTGTG[T/A]GTTGTGAGCAGTGACTACATTACAAACTCAGATCCAGAAATCCTGGAGAACTTAAAGAACTGCAACGAACTCTCGGTTTCCCAAATAGCAGCCATGGAAGCTGTCATCATGAAGGGAACTACTAAATATGGGCAAGTTATCTTGATATTGCAGACTTTTGAGTTGATTCAGAAAATCTTAGTTTCAGTCCTTCGGTTATGATTGTTTAGTAATAAAAATGTATCATTTGTACTTTTTTTTTTAGACCAACAAGCAAGTGGAATCAGAAAACGCTTAACGATTTGGGAATTTTGCCATTGCACTTCTCACAAAACTTTTGGGGATCATTCCAGCAGGTAAACACATGTGAACATGTAATTTGTTTGTTTATTTGCTTGTTTTGAGCATGTTTTGTATTAAAATATACTTCAAAATATTCTTCAAATCTTAAAGTTTAATTCAATGTCTCCCTCTACCACACTATACAGTCAAAAATACAGGTTTTGTGACCATTCCATTTC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461