Busch Lab

ZMP

dnmt5

Ensembl ID:
ENSDARG00000057863
ZFIN ID:
ZDB-GENE-050314-2
Description:
DNA methyltransferase dnmt5 [Source:RefSeq peptide;Acc:NP_001018315]
Human Orthologue:
DNMT3B
Human Description:
DNA (cytosine-5-)-methyltransferase 3 beta [Source:HGNC Symbol;Acc:2979]
Mouse Orthologue:
Dnmt3b
Mouse Description:
DNA methyltransferase 3B Gene [Source:MGI Symbol;Acc:MGI:1261819]

Alleles

There are 14 alleles of this gene:

Allele Name Consequence Status Availability
sa1138 Essential Splice Site F2 line generated Not yet available
sa10487 Nonsense Available for shipment Available now
sa43934 Nonsense Mutation detected in F1 DNA Not yet available
sa32435 Nonsense Available for shipment Available now
sa44997 Nonsense Mutation detected in F1 DNA Not yet available
sa45792 Nonsense Mutation detected in F1 DNA Not yet available
sa37657 Essential Splice Site Available for shipment Available now
sa24282 Nonsense Available for shipment Available now
sa43933 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa43932 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa37656 Nonsense Mutation detected in F1 DNA Not yet available
sa14033 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa1138
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 None None 1296 None 24
ENSDART00000121730 None None 1289 None 22
ENSDART00000125472 Essential Splice Site None 399 2 4
ENSDART00000142297 Essential Splice Site None 1296 2 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17151619)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17054558
GRCz11 23 16980901
KASP Assay ID:
554-1049.1 (used for ordering genotyping assays)
KASP Sequence:
AGTGTAATTCAGTAACAGACCAGTCTAGTGGAGTACATCACCTGCTCAGG[T/C]ATTGTTTTTTTAGTGTTTTTCTTTTTCAGATGTCTAAAACACCTTGATTT
Long Flanking Sequence:
TGAAAGCTGAATAAATAAGCTTTTCACTGGTGTAACTAGACTTTTTAGGATTGGTCAATATTTGGCTGACAAAGTCAACTATTTTTTAAATCTGGGGGTAAAAATGAACAAAACACTGAGAAGATGGCCTTTACAGTTGTCCTGATTAAGTTGTTATGAATGCAGATCACTAACGTTATTAATCAGAAATCGAGTTTATCTTTATGGAGCATCAGCTTTTTTTAATATTCAAAGAACAGTAAATCATTTTGACTCTTACAATGTATTTTTATTTGTTACCAACAATGCACTTGTGCAATATAATACTGGTTTTGTGGTCCAGGGTTTCATATTGTCTTAGTTGAGATGTTTAAAAACTAAAATCAGAACTTGCATATTAATATAAATCATTTATCTACAGGTTATGGAGAATGGTTGTGAATGTAGAGAAACACACGTTTACAAGTTACAAGTGTAATTCAGTAACAGACCAGTCTAGTGGAGTACATCACCTGCTCAGG[T/C]ATTGTTTTTTTAGTGTTTTTCTTTTTCAGATGTCTAAAACACCTTGATTTTTGTATTGAGTTTATTTTATAATTATATTATATTATTAATTATATTATTTCAGGCTTTCTCCTTAATAATATGATTTCAGAAAAGTATTATTTGCAAAAATCTAAATAGTGAAGTTATATTAGCTGCCCATGACTATCAAGGTACAACATTGTTCACAGTCAATTAAATGGTGCTAATGTTGTTTTGAAGTAATTTAAATGTGATTTAAGACCCAATATTCAAATTAGTGTGGTAAACGTATAAAGACAGTTAAATTAACGAATGTGCGAATATAAATCCAACTTTACCTCTGTGATTTTTGTATACCAGTTGTATTTACAGTAATACATTTGTGTGCAATCTCATTTTTCTCAAAATCTTTAAGTATTGTTTGCACTTAATCTTAACATGAACTTTTTGCACTTTTTGTTTTACTGAGTTCAGACTCGTATCTTTATAGAATTACAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10487
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Nonsense 309 1296 3 24
ENSDART00000121730 Nonsense 309 1289 1 22
ENSDART00000125472 Nonsense 309 399 4 4
ENSDART00000142297 Nonsense 309 1296 4 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17149900)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17052839
GRCz11 23 16979182
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCCAGCGTCTTACAACTGCTCCAAGATGCTTCTAAATTATTGAGGCTTTA[C/A]ACACAGAGTTTCCTCAGACCAAAAGCAGCAGAGTATTTTCACAGGAGAGG
Long Flanking Sequence:
TTATATTCAGATTTTCCAGATCACGAACATCTTGTAGCTGGTCTACAGTTAATGAAAGCTGAGATTGTGTCTTTATGTGGACTTACAGACCTGACAGGACAAGTGTGTCACAGTGGTGTTGAGAAAATTGAGTTTTCTGACCTGATTCTGAATCTCATCATAGAGATCTACAAACACTTCCCATCTTTCCCAGCAGATCTACAAGCTTTGCTTGAAGATGTTGAAGGATCAGACATTGATAATCTGACATCTCAGTGCTCTCTCTTCTGGAGAATAATTAAGAAAATCTCTTTAGCTTGGTCACATCTTGAGAAGTACTTTGGATCTCTGGATACAGAAGAAGAAGCAGTCTGCCTTCTTCTAGAGGATCCCAAAATAAAGCTCAACGTTCTCTTTCTTACCCACGCTTTGCAGCCGCTTTGTGATTTTCAGGAGATTATCGACCAAGGTGCCAGCGTCTTACAACTGCTCCAAGATGCTTCTAAATTATTGAGGCTTTA[C/A]ACACAGAGTTTCCTCAGACCAAAAGCAGCAGAGTATTTTCACAGGAGAGGAAAGACCTCACTTGTACAGGAGACAGTGGGACATTTACCTAGAGGAGAGGTTGCAGTCGGCGAACAGGCTGCTGATTTTCTCCAGCAGCACTCTGAAGAGTTGTCTGACTACTTGGAGACATTTCACAGATCCATCATCTCCTTCTACACCACTGTTACTGTTAATATTGTCAAACGTCTGCCTCTCCCTGATTCCACCCTGAGAAACTTGTCGTTGGTGTTGAGTCCAGGAAAAAAGCTTGAAGTGACGGGCAAAATGGTCCAAGATTTAGGCATCGGTTTTGGTGTTTGCTCAGAGAATGTCAGCTTGCTCAAAGACGAGTTTTTGGAGTACCAGTTTATTGATGAAAGTGATGCACAGCCAGCTGACCAGTCAATGAAGCAGTACTGGAAAACAGAGCTGAGGATTATGGGGAAGGCATCTAGTTTTGGGAAAGTCATCCTAAGCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43934
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Nonsense 348 1296 3 24
ENSDART00000121730 Nonsense 348 1289 1 22
ENSDART00000125472 Nonsense 348 399 4 4
ENSDART00000142297 Nonsense 348 1296 4 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17149785)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17052724
GRCz11 23 16979067
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACAGGAGACAGTGGGACATTTACCTAGAGGAGAGGTTGCAGTCGGCGAA[C/T]AGGCTGCTGATTTTCTCCAGCAGCACTCTGAAGAGTTGTCTGACTACTTG
Long Flanking Sequence:
GTGTTGAGAAAATTGAGTTTTCTGACCTGATTCTGAATCTCATCATAGAGATCTACAAACACTTCCCATCTTTCCCAGCAGATCTACAAGCTTTGCTTGAAGATGTTGAAGGATCAGACATTGATAATCTGACATCTCAGTGCTCTCTCTTCTGGAGAATAATTAAGAAAATCTCTTTAGCTTGGTCACATCTTGAGAAGTACTTTGGATCTCTGGATACAGAAGAAGAAGCAGTCTGCCTTCTTCTAGAGGATCCCAAAATAAAGCTCAACGTTCTCTTTCTTACCCACGCTTTGCAGCCGCTTTGTGATTTTCAGGAGATTATCGACCAAGGTGCCAGCGTCTTACAACTGCTCCAAGATGCTTCTAAATTATTGAGGCTTTACACACAGAGTTTCCTCAGACCAAAAGCAGCAGAGTATTTTCACAGGAGAGGAAAGACCTCACTTGTACAGGAGACAGTGGGACATTTACCTAGAGGAGAGGTTGCAGTCGGCGAA[C/T]AGGCTGCTGATTTTCTCCAGCAGCACTCTGAAGAGTTGTCTGACTACTTGGAGACATTTCACAGATCCATCATCTCCTTCTACACCACTGTTACTGTTAATATTGTCAAACGTCTGCCTCTCCCTGATTCCACCCTGAGAAACTTGTCGTTGGTGTTGAGTCCAGGAAAAAAGCTTGAAGTGACGGGCAAAATGGTCCAAGATTTAGGCATCGGTTTTGGTGTTTGCTCAGAGAATGTCAGCTTGCTCAAAGACGAGTTTTTGGAGTACCAGTTTATTGATGAAAGTGATGCACAGCCAGCTGACCAGTCAATGAAGCAGTACTGGAAAACAGAGCTGAGGATTATGGGGAAGGCATCTAGTTTTGGGAAAGTCATCCTAAGCTTGTTGGCCCTTCCCACAACTCTGAAAAAAGAGCAGAATTTTGAACGGGTGAGTTACTGAGTTCATGAACAGCTTGAGAAACCTAGTTATCAAATATCAGTTTGACTAAATAATGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32435
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Nonsense 635 1296 8 24
ENSDART00000121730 Nonsense 627 1289 7 22
ENSDART00000125472 None None 399 None 4
ENSDART00000142297 Nonsense 635 1296 9 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17144726)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17047665
GRCz11 23 16974008
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGCATTTTATTTCTTCAGGGCAGTTACATAGTCGGTGAGATGGTTTGG[G/T]GACCGCTTGAAGGCTTTGGTCTTTGGCCTGGATTGGTTCAGAGCTGGGAC
Long Flanking Sequence:
AGCACTGCGTTTTAAGTTTTTAGGTACAAAGATGCATTCTGCACAAATGTTTCCTAAAGCCGCACATGCTGTGAACATTTTGCAGTGAATACGGGTCGCACGGCAACAATTTTTGCACTCACACAAATGCTCCCAAATATATTTTGAGGTTGCGTAGATAAAAATTTTTTCCAAAACAAACGCAATTTCAAGCTCTGATATGTAGTTTAACAAAAACAAGAGCAATATTTGCACCTCTTACCCCACACATTAATTTTAACACATTTGTGTTAATCTTATCAATGATTCATGGGAAATTCCATATATGGCAGTAACTTGAGAAACAAGGCTTCATAGTGCTAGCAGTGTTTGTACCAAAAGCACTTCTTTAGTGTCTTATGTGGTGCTTTTTTAATCTAAATCACCCAAGTGCACCTGTTATGTGCACCCCTGACTTTATTCCATTTCTTAAGTGCATTTTATTTCTTCAGGGCAGTTACATAGTCGGTGAGATGGTTTGG[G/T]GACCGCTTGAAGGCTTTGGTCTTTGGCCTGGATTGGTTCAGAGCTGGGACAGCAGGAAACCTTGTGGCTCCATGCGTAAAGTGTTTTTCTTCGGAAACAGTATGCAGTCTGAGGTAGAGATTTTATTAGTCTTGTGCAAGATTTTATTTCACCTTATTTCACTTATTAAGAGTGATCATACTTCATATGTTTCCATTGTAGATTCAGGCAGACGATCTCACGCCCTTCTTTTCGTTTGCTAAGTGCTTCTCTTCTAATTCCTTTGCCACGGTAGCAACATATAAAGATGCGATCTTCAATTCTCTGCAGGTAATGAAAGTTCTTATTTTGCTAGCGTCATCTGTTTGGCTCTTTAAGATCTATTTGCCAGGGGGCAGATTTTTACTCTAATTTCTTAGGATTTACCATGGAAATACGAAAATAAATGTTGTTGACGTGAGGTTTTCTACATGATATACTCTAGGTGGCTTCCAGACGTAGTAGAATGTTTTTTTCTCCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44997
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Nonsense 645 1296 8 24
ENSDART00000121730 Nonsense 637 1289 7 22
ENSDART00000125472 None None 399 None 4
ENSDART00000142297 Nonsense 645 1296 9 24
ENSDART00000143180 None None 215 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17144696)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17047635
GRCz11 23 16973978
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAGTCGGTGAGATGGTTTGGGGACCGCTTGAAGGCTTTGGTCTTTGGCCT[G/T]GATTGGTTCAGAGCTGGGACAGCAGGAAACCTTGTGGCTCCATGCGTAAA
Long Flanking Sequence:
GATGCATTCTGCACAAATGTTTCCTAAAGCCGCACATGCTGTGAACATTTTGCAGTGAATACGGGTCGCACGGCAACAATTTTTGCACTCACACAAATGCTCCCAAATATATTTTGAGGTTGCGTAGATAAAAATTTTTTCCAAAACAAACGCAATTTCAAGCTCTGATATGTAGTTTAACAAAAACAAGAGCAATATTTGCACCTCTTACCCCACACATTAATTTTAACACATTTGTGTTAATCTTATCAATGATTCATGGGAAATTCCATATATGGCAGTAACTTGAGAAACAAGGCTTCATAGTGCTAGCAGTGTTTGTACCAAAAGCACTTCTTTAGTGTCTTATGTGGTGCTTTTTTAATCTAAATCACCCAAGTGCACCTGTTATGTGCACCCCTGACTTTATTCCATTTCTTAAGTGCATTTTATTTCTTCAGGGCAGTTACATAGTCGGTGAGATGGTTTGGGGACCGCTTGAAGGCTTTGGTCTTTGGCCT[G/T]GATTGGTTCAGAGCTGGGACAGCAGGAAACCTTGTGGCTCCATGCGTAAAGTGTTTTTCTTCGGAAACAGTATGCAGTCTGAGGTAGAGATTTTATTAGTCTTGTGCAAGATTTTATTTCACCTTATTTCACTTATTAAGAGTGATCATACTTCATATGTTTCCATTGTAGATTCAGGCAGACGATCTCACGCCCTTCTTTTCGTTTGCTAAGTGCTTCTCTTCTAATTCCTTTGCCACGGTAGCAACATATAAAGATGCGATCTTCAATTCTCTGCAGGTAATGAAAGTTCTTATTTTGCTAGCGTCATCTGTTTGGCTCTTTAAGATCTATTTGCCAGGGGGCAGATTTTTACTCTAATTTCTTAGGATTTACCATGGAAATACGAAAATAAATGTTGTTGACGTGAGGTTTTCTACATGATATACTCTAGGTGGCTTCCAGACGTAGTAGAATGTTTTTTTCTCCTGACACGGACTCTATGGATGAGTTGCTTAGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45792
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Nonsense 852 1296 11 24
ENSDART00000121730 Nonsense 844 1289 10 22
ENSDART00000125472 None None 399 None 4
ENSDART00000142297 Nonsense 852 1296 12 24
ENSDART00000143180 None None 215 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17142526)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17045465
GRCz11 23 16971808
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTATCTAAATGACATGGAAAGTATGAAGGTTGACTCCAGACAGAACAGT[C/T]AAGAAAGATGTATGTACATCATTAATATTTGTTGTAGTTAATTTTGCAAT
Long Flanking Sequence:
CTAGTCAAAGTGAAGGGCATAAAAATTGTTCTGGGAGGCAGCCACAGTTAGTTCACCTCAAGTTCTTTGATGCCAGCTTTGTGTGTCCTGTCTTTAACAGTGTACCCAAGAACCATACCTGCCAAGTGGGAGCACACCTTATGTCTCAGTTTTATATTTTTTGTTAATTTGATATGAACTTAACAGTATATTTATTTTTGTTCCTTTTTTTAGAACTGGTTTTTACACCACGATCAGTGAATGGGAATGATGGACCATCTTCAAACTTCAAAGACCATCGAGAAAAGTTGTTTAACTTAACGGTATCTCTCAATAAGCTCCCTGAATCTCTGGATCTGCACAGAGGCTCAATAGACATTGGTAAAACTCATGTTTACAGAAAATTCATGCTTCCAAAAAGGAGTCTGAGACCCTTGCAGTCTAGAGAAAAGAAATATACACACTGGAAGAGGTATCTAAATGACATGGAAAGTATGAAGGTTGACTCCAGACAGAACAGT[C/T]AAGAAAGATGTATGTACATCATTAATATTTGTTGTAGTTAATTTTGCAATGTGTTAACCTAGTGTTTATTACTTTTCACAGATGAAATGGTGCATGCTTTTCTGGAAAACAAGATGGACATTGAAGGTGAAACACTCTTTCATAAGCATTGCGTTAACTGATGATGCTGAGTATTAACAAGTACTTATTTTTTTCCCCCTCTTTCAGAGTTCTGCTTGTCATGTGGGAGTACATTTGTTGACATTATCCACCCACTGTTCGAAGGAAGCCTGTGTGTGAAATGCAAGGTAAAACTGCCATAAACATAGTTCCGCAAAATAAAATGATCCAGACAGTGAGCCTTGAATTGTGATGTGAACAAGACATTGGATGTTTTAGTTAGCCCGTTTGGTAAAACATGTACACTCACCGGCAACTTTATTAGGTACACCTGCCCAACTGCTCGTTAATGCAAATTTCTAATCAGCCAATCACATAGCAGCAACCCCATGCATTTAGGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37657
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Essential Splice Site 896 1296 13 24
ENSDART00000121730 Essential Splice Site 888 1289 12 22
ENSDART00000125472 None None 399 None 4
ENSDART00000142297 Essential Splice Site 896 1296 14 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17142237)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17045176
GRCz11 23 16971519
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGACATTATCCACCCACTGTTCGAAGGAAGCCTGTGTGTGAAATGCAAGG[T/A]AAAACTGCCATAAACATAGTTCCGCAAAATAAAATGATCCAGACAGTGAG
Long Flanking Sequence:
GTTTAACTTAACGGTATCTCTCAATAAGCTCCCTGAATCTCTGGATCTGCACAGAGGCTCAATAGACATTGGTAAAACTCATGTTTACAGAAAATTCATGCTTCCAAAAAGGAGTCTGAGACCCTTGCAGTCTAGAGAAAAGAAATATACACACTGGAAGAGGTATCTAAATGACATGGAAAGTATGAAGGTTGACTCCAGACAGAACAGTCAAGAAAGATGTATGTACATCATTAATATTTGTTGTAGTTAATTTTGCAATGTGTTAACCTAGTGTTTATTACTTTTCACAGATGAAATGGTGCATGCTTTTCTGGAAAACAAGATGGACATTGAAGGTGAAACACTCTTTCATAAGCATTGCGTTAACTGATGATGCTGAGTATTAACAAGTACTTATTTTTTTCCCCCTCTTTCAGAGTTCTGCTTGTCATGTGGGAGTACATTTGTTGACATTATCCACCCACTGTTCGAAGGAAGCCTGTGTGTGAAATGCAAGG[T/A]AAAACTGCCATAAACATAGTTCCGCAAAATAAAATGATCCAGACAGTGAGCCTTGAATTGTGATGTGAACAAGACATTGGATGTTTTAGTTAGCCCGTTTGGTAAAACATGTACACTCACCGGCAACTTTATTAGGTACACCTGCCCAACTGCTCGTTAATGCAAATTTCTAATCAGCCAATCACATAGCAGCAACCCCATGCATTTAGGCATGCAGACATGATCAAGACGATCTGCTGCAGTCAAACTGAGCATCAGAATGGGGAAGATAGGAGATTGTTAGTGACTTTGAACGTGGCATGGTTGTTGGTGCCAGACGGGCTGGTCTGAGTATGTCAGAAACTGCTGATCTACTGGGATTTTCACGCACAACCATCTCTAGGGTTTGCAGAGAATGGTCAGAAAAAGAGAAAATATCCAGTGAGCGGCAGTTCTGTGGGCGCAAATGGCTTGTTGATGTCAGAGGTCACAGGAGAATGGCCAGACTGGTTTGAGCTGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24282
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Nonsense 911 1296 14 24
ENSDART00000121730 Nonsense 903 1289 13 22
ENSDART00000125472 None None 399 None 4
ENSDART00000142297 Nonsense 911 1296 15 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17138243)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17041182
GRCz11 23 16967525
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACATAGTTTAATTTCACGGAGACGCTGTACAGATATGATGAAGATGGCTA[T/A]CAGTCGTACTGCACCGTCTGCTGTTCTGGCATGGAGGTCATTCTGTGTGG
Long Flanking Sequence:
CTGTGGTACAGCGTCACGTGGTAATCTAATGATCCTAAAATATTGGGTTCAATTGACTAAACCTCAAATTATTGCTAACTTTACTAAAAATTGCTAGTTGTTTTTCTTAATTAAAAAAAGTAAACGGTGAAATCAATATTTTATGTAACATTTGTAGTTTAAAATTAAGCAATGTCCAAAACTAAACTTTTTAAGTGAAATCTGTTTATTTAAATCAGCCATATTTACTGTTGCTGGATATCATTTTTTTACAGTGTAGAGTATATTTTCAAGTAGTTAAATAGCCAATTGGATTTTAACTACATCTGTCTATGGTGTCCATCTGCAATGAAGCATTTTTTGCAAATTCTACTTTTTTTGCTGCAGTTCTAGCTACCACTAAACTCTAGTTAGTTAATGCAAAAAGTTCTGGCTGAATGGTTTTTTTATTGCATGTTTTTTTGGTGTCACACATAGTTTAATTTCACGGAGACGCTGTACAGATATGATGAAGATGGCTA[T/A]CAGTCGTACTGCACCGTCTGCTGTTCTGGCATGGAGGTCATTCTGTGTGGTCATGACAGCTGCTGTCGGTAAGTGTGTTTGTGGTGGTCACGAAGAAACCCAGGACAACTAAACCATCCCCCCACTTTTAGGATTTGTAAATGATTGTAAATCATAGAAGCTTTGGGGAAATAGATCTAATGGTGGCTTTTTAAAGAAAGTAATTATTAGATTATACATTTTTATATTGTCATAGCTGTAGGTCCTAACTTAAAGGTCCAAACTATAAAATCTAGTTAAAAAAAAAAAAAATATTTACCAGATTTGAAAAGTTGCATTCCTGTAAAATGTTGATTAGGCCTTATAGCAAAAATCGATGCACTCTATTTTTTTTAAATATATTTTTCTGATACAAATTAATATGTTTTGTATTCATCATATTATATTGTATACATTATCATTAATAGTTCACCAAATGTGGAAACTTTTCAAATGACACCCAGTTACTAAGATTATCAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43933
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Essential Splice Site 934 1296 14 24
ENSDART00000121730 Essential Splice Site 926 1289 13 22
ENSDART00000125472 None None 399 None 4
ENSDART00000142297 Essential Splice Site 934 1296 15 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17138173)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17041112
GRCz11 23 16967455
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTGTTCTGGCATGGAGGTCATTCTGTGTGGTCATGACAGCTGCTGTCGG[T/G]AAGTGTGTTTGTGGTGGTCACGAAGAAACCCAGGACAACTAAACCATCCC
Long Flanking Sequence:
ATTGCTAACTTTACTAAAAATTGCTAGTTGTTTTTCTTAATTAAAAAAAGTAAACGGTGAAATCAATATTTTATGTAACATTTGTAGTTTAAAATTAAGCAATGTCCAAAACTAAACTTTTTAAGTGAAATCTGTTTATTTAAATCAGCCATATTTACTGTTGCTGGATATCATTTTTTTACAGTGTAGAGTATATTTTCAAGTAGTTAAATAGCCAATTGGATTTTAACTACATCTGTCTATGGTGTCCATCTGCAATGAAGCATTTTTTGCAAATTCTACTTTTTTTGCTGCAGTTCTAGCTACCACTAAACTCTAGTTAGTTAATGCAAAAAGTTCTGGCTGAATGGTTTTTTTATTGCATGTTTTTTTGGTGTCACACATAGTTTAATTTCACGGAGACGCTGTACAGATATGATGAAGATGGCTATCAGTCGTACTGCACCGTCTGCTGTTCTGGCATGGAGGTCATTCTGTGTGGTCATGACAGCTGCTGTCGG[T/G]AAGTGTGTTTGTGGTGGTCACGAAGAAACCCAGGACAACTAAACCATCCCCCCACTTTTAGGATTTGTAAATGATTGTAAATCATAGAAGCTTTGGGGAAATAGATCTAATGGTGGCTTTTTAAAGAAAGTAATTATTAGATTATACATTTTTATATTGTCATAGCTGTAGGTCCTAACTTAAAGGTCCAAACTATAAAATCTAGTTAAAAAAAAAAAAAATATTTACCAGATTTGAAAAGTTGCATTCCTGTAAAATGTTGATTAGGCCTTATAGCAAAAATCGATGCACTCTATTTTTTTTAAATATATTTTTCTGATACAAATTAATATGTTTTGTATTCATCATATTATATTGTATACATTATCATTAATAGTTCACCAAATGTGGAAACTTTTCAAATGACACCCAGTTACTAAGATTATCAAAAAATGGTTTCATAGTTGAAAGGTAATATTTCTTTTTAAGGATTTTCAACATTTTACAACAAAAACGATCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43932
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Essential Splice Site 1103 1296 18 24
ENSDART00000121730 Essential Splice Site 1095 1289 17 22
ENSDART00000125472 None None 399 None 4
ENSDART00000142297 Essential Splice Site 1103 1296 19 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17135173)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17038112
GRCz11 23 16964455
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTTGTAATGACTTGTGCACAGTCAATCCTGGCCGTAAAGGCTTGTTTGG[T/C]AAGACAAATCTGTTGCACTTTACACACAATATGATTTGCCTGGCATCATG
Long Flanking Sequence:
GCAGCAGGAACTGGTTTTTCCCGCATTCCTCCCTGGTGGGTTGTGAAGTCACCAGTCTCTGTTTTCAGCTCATGTTTTGAATTGTCAAAGATATCAGAATATTTGCAATATTTCAATTCTTACAACTTGCAGTTTAATACATGCTCACAGTATGTTCTTGTCAATGTCGTTTCAGGATACCTGGTTCTGAGAGATCTTGGCTTCAAAGTGGAAAAATACGTGGCCTCTGAAGTGGATGAAGAGTCTGTTACCATTTCCATGGTCAACCACGAGGGAAAAATCACCTATGTTGATGATGTGAAAAAAATTACAAGGAAACACGTATGTTTGCAAAATGAGTATTTTAATTATGTATCTGAAGATGATTCCTCTGCAGTTGGCTTATTGAGTTTTTTTCTTATTGTTCAGATTGATAAATGGGGCCCGTTTGATCTTCTAATTGGTGGAAGTCCTTGTAATGACTTGTGCACAGTCAATCCTGGCCGTAAAGGCTTGTTTGG[T/C]AAGACAAATCTGTTGCACTTTACACACAATATGATTTGCCTGGCATCATGCAGCTTTATAGAACTAGAATGCACACTTTTAATAAAGGTGTGGCAACCTTTTTGCTGATAATCAAAAGTCTGGATACACAAGCACATGGTTCACATCATGTTTTTTATTGAAGAGACTTCTGCTAAATGTGCCTCATTTTAAAACCGATAATTACATGTAATTGATTGGTCTGCTTTGCTCTCTGCAGAGGGCTCTGGACGGCTGTTTTTTGAGTACTACCGGCTTCTGAACGTTTTGAAGCCGAAAGAGGATGACCCACGGCCCTTCTTCTGGCTCTTTGAGAATGTAGTGTTAATGGAAAACAGGGTTAGAGCGGACATAAGCCGCTTTCTGGAAGTGAGTATTTTACTTTATGCTACATAAAGGTTTGATAAAGACTCTCAGCAATTCATGCAAATTTAGTGGGTGTTTGTTTCGTAATTTTTTGAGCTTTAGTATGTGACCCTGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37656
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Nonsense 1119 1296 19 24
ENSDART00000121730 Nonsense 1111 1289 18 22
ENSDART00000125472 None None 399 None 4
ENSDART00000142297 Nonsense 1119 1296 20 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17134886)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17037825
GRCz11 23 16964168
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAGGGCTCTGGACGGCTGTTTTTTGAGTACTACCGGCTTCTGAACGTTT[T/A]GAAGCCGAAAGAGGATGACCCACGGCCCTTCTTCTGGCTCTTTGAGAATG
Long Flanking Sequence:
TGTTGATGATGTGAAAAAAATTACAAGGAAACACGTATGTTTGCAAAATGAGTATTTTAATTATGTATCTGAAGATGATTCCTCTGCAGTTGGCTTATTGAGTTTTTTTCTTATTGTTCAGATTGATAAATGGGGCCCGTTTGATCTTCTAATTGGTGGAAGTCCTTGTAATGACTTGTGCACAGTCAATCCTGGCCGTAAAGGCTTGTTTGGTAAGACAAATCTGTTGCACTTTACACACAATATGATTTGCCTGGCATCATGCAGCTTTATAGAACTAGAATGCACACTTTTAATAAAGGTGTGGCAACCTTTTTGCTGATAATCAAAAGTCTGGATACACAAGCACATGGTTCACATCATGTTTTTTATTGAAGAGACTTCTGCTAAATGTGCCTCATTTTAAAACCGATAATTACATGTAATTGATTGGTCTGCTTTGCTCTCTGCAGAGGGCTCTGGACGGCTGTTTTTTGAGTACTACCGGCTTCTGAACGTTT[T/A]GAAGCCGAAAGAGGATGACCCACGGCCCTTCTTCTGGCTCTTTGAGAATGTAGTGTTAATGGAAAACAGGGTTAGAGCGGACATAAGCCGCTTTCTGGAAGTGAGTATTTTACTTTATGCTACATAAAGGTTTGATAAAGACTCTCAGCAATTCATGCAAATTTAGTGGGTGTTTGTTTCGTAATTTTTTGAGCTTTAGTATGTGACCCTGGACACAAAACCAGTTGCGTTTCACAGGTATGTTTCTGGCAGCAGCCAAAATTATATTGTATGGGTCAAGATTACCCAATTTTCTTTTACGCCAAAAATTATTGGAATGTTAATTTAGAAATTAAGTATGTGTGATTCTGCTTACCCGACTGACAGTAGCTATGTTTCCATCCAAAAATGCGAATGAACTTTTTGCAAAACTGGATTATCGCATAAAATACATTCGAATAAAGCAGCGTTTCCATCCAACGAGTCAAATCGAACAAAAGCGTCACTTCCTGATTAACTGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14033
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046889 Nonsense 1196 1296 21 24
ENSDART00000121730 Nonsense 1189 1289 20 22
ENSDART00000125472 None None 399 None 4
ENSDART00000142297 Nonsense 1196 1296 22 24
ENSDART00000143180 None None 216 None 3

The following transcripts of ENSDARG00000057863 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 17132773)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 17035712
GRCz11 23 16962055
KASP Assay ID:
2261-7492.1 (used for ordering genotyping assays)
KASP Sequence:
ACTAGACCAAWCATAGCATCACAGAAAGATAAAGTCAGTCTTCAGGACTG[T/A]CTGGATGGAGGCCGCACTGCCAAGGTTTGTCATGASCTTYCTACTAAAGA
Long Flanking Sequence:
CAGACCACAGAACCTTATGTGTTCTGTCGTCTAGTATTTCTTTACAAATGGACATCGCCTGCAAAATACAGCATTTTTAGTCAGTTAAATTGATCTTTATGAACAGGATTTTTTAAAATAAAAAGGAACATGGTGTTAATAGATTTTTGTAGATTCCAATGATGTCTTGAGTGTATTAGATTTTCTTTCTCGAATCCTAACCTCACATTTTTATAGCCGTGTTTATTAGTCGCCTGGTATAGTATGTGTGTGTGGTTTTTGTTTTTAGTGTAACCCTGTGCTTATTGACGCTGTGAAAGTGAGTCCAGCTCACAGAGCAAGATACTTTTGGGGGAACATACCTGGCATGAACAGGTGCGTCAGTTGTATTCATGTGACTGTCACCCTCACTTATAAGATACTGTAAATGAATATGATATTGGGACTTAGTTTTATTTCTTTTTTTTTTTGACTAGACCAATCATAGCATCACAGAAAGATAAAGTCAGTCTTCAGGACTG[T/A]CTGGATGGAGGCCGCACTGCCAAGGTTTGTCATGAGCTTCCTACTAAAGATATGCAGTCATTTGTTAAGATAAGTACGTTTAATATTAAGTTCTGAAACCATGTCCTATTTTGCAGTATGAAAAAATACGCACCATTACCACACGGCCAAACATACTGAGACCAGGCATTGATGACAGGCATTACCCAATCGTTATGAACGGCAAAGATGACAGCCTGTGGATCACTGAAATAGAAAAGTAATCATAATGTTATCGATAATAATAATACAACTCTTTTAGTTTTCACTCAATCACAATAACCTGTTATTTGCTTTGTCAGAATATTTGGATTTCCGAAGCATTACACGGATGTGAAAAATCTGGGCCGCATGCAGAGGCAGAGAGTACTGGGGAAGTCCTGGAGCGTTCCTGTCATAAGACATCTTTTAGCACCACTGAAGGATTACTTTGCTTGTGACGAATTCCCTGCAAAATGAAGAGAAATTTATGAAGCATTTTG
Associated Phenotype:
Not determined