Busch Lab

ZMP

hsp90a.1

Ensembl ID:
ENSDARG00000010478
ZFIN ID:
ZDB-GENE-990415-94
Description:
Heat shock protein HSP 90-alpha 1 [Source:UniProtKB/Swiss-Prot;Acc:Q90474]
Human Orthologues:
HSP90AB1, HSP90AB4P
Human Descriptions:
heat shock protein 90kDa alpha (cytosolic), class B member 1 [Source:HGNC Symbol;Acc:5258]
heat shock protein 90kDa alpha (cytosolic), class B member 4 (pseudogene) [Source:HGNC Symbol;Acc:32
Mouse Orthologue:
Hsp90ab1
Mouse Description:
heat shock protein 90 alpha (cytosolic), class B member 1 Gene [Source:MGI Symbol;Acc:MGI:96247]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa30722 Nonsense Mutation detected in F1 DNA Not yet available
sa1396 Nonsense F2 line generated Not yet available
sa16631 Nonsense Available for shipment Available now
sa14009 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa30722
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004756 Nonsense 398 725 7 11
Genomic Location (Zv9):
Chromosome 20 (position 54342824)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 54198227
GRCz11 20 53987673
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGTGGACTCTGAGGATCTGCCTCTGAACATCTCCAGAGAAATGCTTCAA[C/T]AGAGCAAAATCCTGAAGGTGATCCGCAAAAACCTGGTCAAGAAGTGTCTC
Long Flanking Sequence:
TAAGACAACTTTCAAAGGTTTTGAACCACTTCAAATGTTGACAACTGTATATCAATGTCAACCAATAGAATAAATGCTGACTTTCCTTGACTCTAGTCTGTTAAGTTATTAGACAATAATGCTCTACTTCAGGTGTGGATTATATAAGGCATAATTGCCATACTTAAAGGATATTAAATGCATGATGCAGAAGAAACTAAGCATCCATGTTTGATGAAAGCACATTTATTTTTTGTTAACTGTGATCAAAACTGACTGGAACTACCTGTGTGCATTAAAAATAATATTACACACTTTCCAGCCAATCAGAAACGAGTATTTCAACAGACCATTGTGTCATTTCTAACAATTCAATTGTTTGTTCTCAATTATTTCTTACTCATTCCAAAGTAATAATACACTATATAACATTCACAAAATCAACATTCCTTCCAGACTTTATTAAGGGTGTGGTGGACTCTGAGGATCTGCCTCTGAACATCTCCAGAGAAATGCTTCAA[C/T]AGAGCAAAATCCTGAAGGTGATCCGCAAAAACCTGGTCAAGAAGTGTCTCGATCTCTTCACCGAACTGGCAGAGGATAAAGACAACTATAAGAAATACTACGAGCAGTTCTCCAAAAACATCAAGGTGAATGTGCTACTCAAGTAACTAACGAACACAGAAATATAGAAAGTGCCCAAAATAACATGTTTCTTCTTCTTTTAGCTTGGCATCCACGAGGACTCTCAGAATCGCAAGAAACTTTCTGATCTTTTGCGCTACTACACTTCAGCTTCAGGAGATGAGATGGTGTCACTTAAAGACTATGTGTCTCGCATGAAGGACACACAGAAGCACATCTACTACATCACCGGTTAGTAGCGATTCAGTGAATTAACAGTCAGTGTTTTGAGTTATGGATTATAAGAAATGAGAGTTATGTAATCATTTACTTGAAAAAGTAATCTGATTACATAAGTTGGATTACCCTTAATAAATGAAAAAACTAATGAGTAATTTGCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1396
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004756 Nonsense 413 725 7 11
Genomic Location (Zv9):
Chromosome 20 (position 54342777)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 54198180
GRCz11 20 53987626
KASP Assay ID:
554-1308.1 (used for ordering genotyping assays)
KASP Sequence:
CAACAGAGYAAAATCCTGAAGGTGATCCGCAAAAACCTGGTCAAGAAGTG[T/A]CTCGATCTCTTCACCGAACTGGCAGAGGATAAAGACAACTAYAAGAAATA
Long Flanking Sequence:
TATATCAATGTCAACCAATAGAATAAATGCTGACTTTCCTTGACTCTAGTCTGTTAAGTTATTAGACAATAATGCTCTACTTCAGGTGTGGATTATATAAGGCATAATTGCCATACTTAAAGGATATTAAATGCATGATGCAGAAGAAACTAAGCATCCATGTTTGATGAAAGCACATTTATTTTTTGTTAACTGTGATCAAAACTGACTGGAACTACCTGTGTGCATTAAAAATAATATTACACACTTTCCAGCCAATCAGAAACGAGTATTTCAACAGACCATTGTGTCATTTCTAACAATTCAATTGTTTGTTCTCAATTATTTCTTACTCATTCCAAAGTAATAATACACTATATAACATTCACAAAATCAACATTCCTTCCAGACTTTATTAAGGGTGTGGTGGACTCTGAGGATCTGCCTCTGAACATCTCCAGAGAAATGCTTCAACAGAGCAAAATCCTGAAGGTGATCCGCAAAAACCTGGTCAAGAAGTG[T/A]CTCGATCTCTTCACCGAACTGGCAGAGGATAAAGACAACTATAAGAAATACTACGAGCAGTTCTCCAAAAACATCAAGGTGAATGTGCTACTCAAGTAACTAACGAACACAGAAATATAGAAAGTGCCCAAAATAACATGTTTCTTCTTCTTTTAGCTTGGCATCCACGAGGACTCTCAGAATCGCAAGAAACTTTCTGATCTTTTGCGCTACTACACTTCAGCTTCAGGAGATGAGATGGTGTCACTTAAAGACTATGTGTCTCGCATGAAGGACACACAGAAGCACATCTACTACATCACCGGTTAGTAGCGATTCAGTGAATTAACAGTCAGTGTTTTGAGTTATGGATTATAAGAAATGAGAGTTATGTAATCATTTACTTGAAAAAGTAATCTGATTACATAAGTTGGATTACCCTTAATAAATGAAAAAACTAATGAGTAATTTGCGAAACAACATTTTGGAAGAGGTTTTCTTTTAAGGTAAAAAGTAATCCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16631
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004756 Nonsense 597 725 10 11
ENSDART00000004756 Nonsense 597 725 10 11
Genomic Location (Zv9):
Chromosome 20 (position 54338757)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 54194160
GRCz11 20 53983606
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTCTCCAACCGTCTGGTGTCTTCGCCCTGCTGTATCGTCACCAGCAMATA[C/A]GGYTGGACGGCRAAMATGGAGAGGATCATGAAGTCTCAGGCTCTGAGGGA
Long Flanking Sequence:
TAGTTTCGGTTTCAATCAAGTCGTCCGCATAAGATCAACACATTCAGTTCGAGAAGAAAATTCACATTCACAATTCACAAATTGAAGCAAAAAACATCCTTTGAGTAATCGAGAGCGAGTGACGAGATGCTAATTTTCGTAAACAAAATTACGAATTTGAACTGGTAGATTACACACAAAGTCAATGAGTATGTGAAAAAATAGTAGTAATCCACGCAGAATTTCCAGAGGGTGTATTACTACTATTTGATCATGCATATAATTTGATTCTGAACAGGTCACAGTCTCCGACCATTTAATCTTTAACAACTAAAAAATCATGCGAGCTAATGACTCAAAGCAAATGCCCAAATAGAGGTGAAAATCCACTGGGTGGCACGAATGAGGCAAAATACACAGTGTATTACTATTACTTGCTCATGCATATAATTTGTGTCTGAATAGGTCACCGTCTCCAACCGTCTGGTGTCTTCGCCCTGCTGTATCGTCACCAGCACATA[C/A]GGCTGGACGGCGAACATGGAGAGGATCATGAAGTCTCAGGCTCTGAGGGATAACTCTACCATGGGCTACATGACCGCTAAAAAGCACCTAGAAATAAACCCAGCACACCCCATCGTGGAGACCCTCAGAGAGAAAGCGGAAGCCGACAAAAACGACAAGGCGGTGAAGGATCTGGTGATCCTGCTGTTCGAGACGGCGCTCTTATCCTCAGGCTTCACACTGGACGACCCACAGACTCATGCAAACCGCATCTACAGGATGATCAAACTCGGACTTGGTAAGTCTGATGGCTACAGAAGCTAGAGAACTTTATTATATAATATAGTCACAGTTGGATTTGTGTATTGCATGTATGGGGGGCCTAACTATGAGAAGAATACTTAATTATTATTTATTCATAATAATTATTATTATTATAAATATTATTAATACTTAATAATGAAGAATAATTACTATTAATATTAATAGTTTTATATAAAAATGGGCCTTTTGGATGGGGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14009
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004756 Nonsense 597 725 10 11
ENSDART00000004756 Nonsense 597 725 10 11
Genomic Location (Zv9):
Chromosome 20 (position 54338757)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 54194160
GRCz11 20 53983606
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTCTCCAACCGTCTGGTGTCTTCGCCCTGCTGTATCGTCACCAGCAMATA[C/A]GGYTGGACGGCRAAMATGGAGAGGATCATGAAGTCTCAGGCTCTGAGGGA
Long Flanking Sequence:
TAGTTTCGGTTTCAATCAAGTCGTCCGCATAAGATCAACACATTCAGTTCGAGAAGAAAATTCACATTCACAATTCACAAATTGAAGCAAAAAACATCCTTTGAGTAATCGAGAGCGAGTGACGAGATGCTAATTTTCGTAAACAAAATTACGAATTTGAACTGGTAGATTACACACAAAGTCAATGAGTATGTGAAAAAATAGTAGTAATCCACGCAGAATTTCCAGAGGGTGTATTACTACTATTTGATCATGCATATAATTTGATTCTGAACAGGTCACAGTCTCCGACCATTTAATCTTTAACAACTAAAAAATCATGCGAGCTAATGACTCAAAGCAAATGCCCAAATAGAGGTGAAAATCCACTGGGTGGCACGAATGAGGCAAAATACACAGTGTATTACTATTACTTGCTCATGCATATAATTTGTGTCTGAATAGGTCACCGTCTCCAACCGTCTGGTGTCTTCGCCCTGCTGTATCGTCACCAGCACATA[C/A]GGCTGGACGGCGAACATGGAGAGGATCATGAAGTCTCAGGCTCTGAGGGATAACTCTACCATGGGCTACATGACCGCTAAAAAGCACCTAGAAATAAACCCAGCACACCCCATCGTGGAGACCCTCAGAGAGAAAGCGGAAGCCGACAAAAACGACAAGGCGGTGAAGGATCTGGTGATCCTGCTGTTCGAGACGGCGCTCTTATCCTCAGGCTTCACACTGGACGACCCACAGACTCATGCAAACCGCATCTACAGGATGATCAAACTCGGACTTGGTAAGTCTGATGGCTACAGAAGCTAGAGAACTTTATTATATAATATAGTCACAGTTGGATTTGTGTATTGCATGTATGGGGGGCCTAACTATGAGAAGAATACTTAATTATTATTTATTCATAATAATTATTATTATTATAAATATTATTAATACTTAATAATGAAGAATAATTACTATTAATATTAATAGTTTTATATAAAAATGGGCCTTTTGGATGGGGG
Associated Phenotype:
Not determined