Busch Lab

ZMP

PTK2B (1 of 2)

Ensembl ID:
ENSDARG00000022841
Description:
PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]
Human Orthologue:
PTK2B
Human Description:
PTK2B protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:9612]
Mouse Orthologue:
Ptk2b
Mouse Description:
PTK2 protein tyrosine kinase 2 beta Gene [Source:MGI Symbol;Acc:MGI:104908]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa22987 Nonsense Available for shipment Available now
sa36298 Nonsense Mutation detected in F1 DNA Not yet available
sa13889 Nonsense Available for shipment Available now
sa2896 Essential Splice Site F2 line generated Not yet available

Mutation Details

Allele Name:
sa22987
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028407 Nonsense 301 933 9 29
Genomic Location (Zv9):
Chromosome 17 (position 5925475)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 6004411
GRCz11 17 6161641
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAAATTCGAAGTATTAAATGCACACATCAGAACGATGGAAAGGCACTGT[T/A]ACATATCAATATAGAAGGAGCTAAACAGGTAAATGCATCTGTCTTTAACT
Long Flanking Sequence:
ATTATTTAATTGTAAATTAGATGGCATTTGTCTTTATTCATATTTAGTATAATGCATTGATTAATGTTTTAATTTGTATATTTTTTTTAAATGTTAGTTTTAATGTCTTTGGCGTCATTTAGATCATTTTAATTAATATTTATATGTATTTAATACTTTATTTTAAAATGTTTTTGTCTGTCTTTTTTTGTTATTTTTTTAACAGTGCACACCATTTATAAAAAAATTTATTTCAACGTTACTGTAACTTTTTTACCTCAGGTAAAATTAAATAAAAATTAGTATGTTACATTTTAAAGTACTTGAATATATTGTGTAATTGTTTTATTTCAGTAAAAGTTTGAAAATTAACTATTTTATTCATTTATTTATTTATTCATTTTAACTAAATATTGAATTAATGCTGGTCTTTTTGTTTCCTCATTAGCCGGTATCTCTTGCCACATTTTCACAAATTCGAAGTATTAAATGCACACATCAGAACGATGGAAAGGCACTGT[T/A]ACATATCAATATAGAAGGAGCTAAACAGGTAAATGCATCTGTCTTTAACTTGTTTTAGATTTGCGGGTCAGTTTCAGGCTGTTTCTCTTTGTATTCTTTAAACTGGTATTACATACGACAAATGTATAATTTACAGTAACCTGAATCCATTGATAATGTTCAAGGCTAAATGCCTGAATGTGATAGGGAACATTTGATTGTAAAACTATTTCTTTTGAAATTTTTTGTTAAACTTTTTAAGGCAAAAGATTTGACAATTTCAAAATTGACACTGACAGAGTTAACAACGACAGAGTTGACAAATAACAGAATTGACAAAAATAGTTGACAAATAGCAGAGTTGACAACGACAGTTGACAAATAGCAGAATTGACAATGACAGAGTTGACAATGACAGAATTGACAATGACAGAGTTGACAATGACAGAGTTGACAATGACAGAATTGACAATGACAGAGTTGACAATGACAGAGTTGACAATGACAGAATTGACAATGAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36298
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028407 Nonsense 384 933 13 29
Genomic Location (Zv9):
Chromosome 17 (position 5918223)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 5997159
GRCz11 17 6154389
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCATCTCTCGTTGTTTTTTGCAGATTCAGATATTTATGCAGAGATACCC[G/T]AAGAAAAACCACTTGCAGGTAAGAACCAAATAATGATTTATGCTTTAATT
Long Flanking Sequence:
AATCACGCCAAACATGTCTTGCACCCTTTTACGCAGAGTGTATGATAGGGCCCAAAATGTGAATTGTGTTTATGATTTATTTGTTTATTTATTATTTAATGTTTGCTTGTGTTTAATAGACAGAGAATCCAGAAACTCTCTACCTCCATTACCCGGCAGGTGAACACTGATGCTTTTCTTTTTCTGTATTTTGTCCTTTTATATATTTTAATTGCATATGATTTTATGTATATGATATCATTATATGTAACTCCACCCATTTGTTTTTAATCTCAATGTCTCAAATCATATATTGGAAATTAGCAAGGAGAATACCACATCTCACAAGGAAGGCAAAAGTATGTAAACCCAGATAAATTCAGTGTATATGTTTACTGTTTATAATATAATTATTTATTATTAAAGCCAAATTTTTCAATATCTAATAATGTCTTTAATATTCTAAATTATTTCATCTCTCGTTGTTTTTTGCAGATTCAGATATTTATGCAGAGATACCC[G/T]AAGAAAAACCACTTGCAGGTAAGAACCAAATAATGATTTATGCTTTAATTGTCATTCATTCATTCATTCATTCATTCATTCATTCATTCATTCATTCATTCATTCATTCATTCAATTAATTATTAATTCAATGATTAATTCATTCAATTATTTATTCATTCATTCAATGATCCATTTATTCATTCATACTATCATTTTTAGATTCATTCATTCATATAATCAACCTTTAATTTTTTAATGAGTTAATTTATTCAAGGATTCACTCATTTATCAATCAATCCAAAGATTCATTCATTAATTCATTCATGTAATTATTCATTCAACCATGAGTTTATTCATTCAATCAATTATTTATTCATTCAATCAGTGAGTAATTAATTTATTCAGGGATTTTTACATTTAATTATTCACTGATTTAAGGATTTATTCATTCAATCATTCATTTATTCAATCATTCATTCGATGATTTATTTATTAACTCAGTGATTAATTAATTTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13889
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028407 Nonsense 602 933 20 29
Genomic Location (Zv9):
Chromosome 17 (position 5907705)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 5986641
GRCz11 17 6143871
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCTGTGTGTATGTGGGAGATCATGAGCGGAGGTCAGCAGCCGYTCTTCTG[G/A]CTGGAGAATAAAGATGTGAWCAACCAATTGGAGCAGGGCATGCGTCTGCC
Long Flanking Sequence:
AGACTGCGTATAAAAAAGGTTTATTCTTCTAAATTTCCCAACAAGCTGACTTTAGAGGCAGATATGTAACAAATATTGCTGTAAATTTTAAACAAACATGTCATAAAAGCTCTTATATTCTCATACCTCTTCATTTGTAGCATTGTTATGAAAGATCTCAGTTTGAAGGGCTGTCTGACCCCTACATATCCAACAAAAGTAAATAAATATTTGAACATCATTTAAATTCTGATAACCTTACTTCATGACTTGACAGAATAAGCCAGTCTGTCAGAAAGTGGCTGATGGCTGTGAAAAGCATTGTCTGGTAAAATGTTAATGTTGTATTCGTGTGGTTACACCAATAAATAAAGGCACATTAAACACAAAGTATAGTTCTGTCCATCTTGCAACACTCAGAGGCTCGTACTTGTTCATATGTTTGCTGATGGTGTGTGTGTTGTGTTTCCAGCTGTGTGTATGTGGGAGATCATGAGCGGAGGTCAGCAGCCGTTCTTCTG[G/A]CTGGAGAATAAAGATGTGATCAACCAATTGGAGCAGGGCATGCGTCTGCCCAAACCTGAGCGCTGCCCGCCGACGCTCTACTCTCTGATGACCCGCTGCTGGAGCTACAGCCCGAGAGACAGACCCAGCTTCACTGAGCTTGTCTGTAAACTCAGGTGAGTCACCTGAGGGAAACCTGCAGCAGAGACTGAAATTTGATTAGTTAGCATACATTTATGCTATAGCTCAGTTGGGAGAGAGTTAGACTGAAGATCTAAAGGTCCCTTGTTCGATCCCGGGTTTCGGCAAAACAGTGCTGACGTTCTGGGGCGAAGCAGTGGCGCAGTAGGTAGTGCTGTCGCCTCAAAGCAAGAACGTCGCTGGGTCACTGGTTTGAGCCTCGGCTCAGTTGGCGTTTCTGTGTGGAGTTTGCATGTTCTCCCTGCATTCGCATGCGTTTCCTCCGGGTGCTCCAGTTTCCCCCACAGTTCAAAGACATGCAGTACAGGTGAATTGGGAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2896
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028407 Essential Splice Site 755 933 24 29
Genomic Location (Zv9):
Chromosome 17 (position 5894204)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 5973140
GRCz11 17 6130370
KASP Assay ID:
554-2539.1 (used for ordering genotyping assays)
KASP Sequence:
TTAATTCTGACTTCATCTGTAGCAAGTCACCTTTTCTTGTTTCTCGTTTA[G/A]GTTCCGTTTGCTAATGAAGACATGAAAACGAAAGCGGTAAAGCTTATCTA
Long Flanking Sequence:
TTGCATAATATTGCACGGCTATCAGCCAACAATCAGATTGGAGTACCAGACAGAACTGTTTGTTGTAATATTTGACTAGAAATTTTTCAAGACACTTCTATACAGCTTAAAGTGACATTTAAAGGCTTAACTAGGTTAATTAGGTTAACTAGGCAGGTTAGAATAATTAGGCAAGTCATTGTATAACAGTGGTTTGTTCTGTAGACTATTGAAAAAAATAGCTTAAAGGGGCTAATAATTTTGACCTTATAATGGTATTTAAAAAAATAAAAACTAAAAATATAAAAAAAATAAAAATAAAAAGCTTTTATTCAAGCCGAAATGAAACAAATAAGACTTTCTCCAGAAGAAAAAACATATGATCAGACATACTGTGAGAATTTCCTCACTCTGTTAAACATCATTTGAGAAATATTTAAAAAATAAATAAATAAATAAAAAGGGGAGCTATTAATTCTGACTTCATCTGTAGCAAGTCACCTTTTCTTGTTTCTCGTTTA[G/A]GTTCCGTTTGCTAATGAAGACATGAAAACGAAAGCGGTAAAGCTTATCTACTTTTTACTGTCATGCCTTTTTTCTGCTGTTGTTTTACACTGTCTTGATTTTATGTTTTTTTTTGTTTCAGACCACAGAAAATGACACTGGCCAAGGTTGTTTTTTTATGTTTGTGTTGTTTAGCTTTCATTTATATTTCATTTATTTTTTAATCATTTTAATGCTTCAAACTAAATGCAATACTGTTATTTTTATATTTATGTCATTTATATAAGTTTTTATTATCAATTTCATGTTGAAATTTATCAACAAGAATTTCATGTTGTTCAATAACAAAGATATATACATTAGATGTCGCCTACCCTGTTGTTGTCTATTGGAAGGAATGCGTCAATAGAGCCGCCATTTTGGAACAGGGTAGCGCTCCATTGAAATGAATGCGAGACCAAGGTACAGTGGAGGACTGTGGCCATCCAAAGCCAGAGATATACACATATACAAATATATCT
Associated Phenotype:
Not determined