ZMP

sirt2

Ensembl ID:

ENSDARG00000011488

ZFIN ID:

ZDB-GENE-030131-1028

Description:

NAD-dependent deacetylase sirtuin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q7ZVK3]

Human Orthologue:

SIRT2

Human Description:

sirtuin 2 [Source:HGNC Symbol;Acc:10886]

Mouse Orthologue:

Sirt2

Mouse Description:

sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) Gene [Source:MGI

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa13413	Nonsense	Available for shipment	Available now
sa9082	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa13413

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
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Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000013278	Nonsense	53	379	4	16

Genomic Location (Zv9):

Chromosome 15 (position 6674972)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	6792263
GRCz11	15	6789356

KASP Assay ID:

2260-8145.1 (used for ordering genotyping assays)

KASP Sequence:

CAGTGGATTTTTTGCGCAGTCTTTTCTCGCGAACACTTGGCCYTAGTCCT[G/T]GAGATAAAGTCTTGGATGAGTTAACCCTGGACTCAGTTGCTCGCTACATA

Long Flanking Sequence:

GCTGGTCAACCAGCTAAAACCAGCCAACCAGCCTAGGCTGGTTTAAGCTGGATTTTTCAGCAGGGTTGCATCAACATCATTGTAAAATTTTCATTCAAATATATACCTTACCGTTTTTCTAGTTTTTTTTTTTGTTTGTTTGTTCTCATAGTAGTTTTTGCTCACACAAAATACACATCTATATGTAAAGCTGAACATGTAAGACATGAACATGATATAAGTTTAAATATTGCTCATATGTCACACTTTCACCACAGTAAGCTGCATTTTATAAAATGATTTTAAATGTATATACATATTTCTGCAGGGTCAGTCAGATGATAGCAGTGACGAGGGTGACGCTTCAGGAGATACTGAGAGTATGTGACAAACACTGTACTTAAAAAGTCATGCATAAAAAAATACTGTCCATAAAATCATGCAATTTTAGCTAAAGATATACTTCTTTTTCAGTGGATTTTTTGCGCAGTCTTTTCTCGCGAACACTTGGCCTTAGTCCT[G/T]GAGATAAAGTCTTGGATGAGTTAACCCTGGACTCAGTTGCTCGCTACATACTGAGTGGCAAATGTGAGTTTCTGCTCAGATGAGGTCCTAACTTTCAGAGTTAAATGTTTAATCTTTTGCTCTTAAAAGACTTAATTTTGAATGTACAGTCTATTCATTAACAAATTGATTTGAAAATTAGCTTCATGAACACTTTGCTGCTGTGCAAATAGCGCTACTATTTTGTGTTATCATTTCAAGTCTTATAGTCAGATGTTTTAAACTGTCAAATAGTTGATATATCTTTCTATCAACAGGTAAGAACATTATCTGTATGGTTGGAGCTGGGATATCTACATGTAAGTGTAAAATGCAGCAATCCACTCCTCATATATGAAAATAGAATTGTATAATATCATAATTATTGGGAGTAGTCGTAGTATTGAATATTATATTAAAAGAATAGTTCATTCACTGATAAATTACTAAAATAAAAAAAACCTGCAACCATTGACTTCCAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa9082

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000013278	Nonsense	102	379	6	16

Genomic Location (Zv9):

Chromosome 15 (position 6677194)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	6794485
GRCz11	15	6791578

KASP Assay ID:

2260-8146.1 (used for ordering genotyping assays)

KASP Sequence:

TCTTTAGCTGCAGGAATCCCAGATTTCCGCTCTCCTGGCACGGGCTTATA[T/A]GCAAATCTGCAGAAGTACAACCTGCCTTACCCAGAGGCCATCTTTCAGAT

Long Flanking Sequence:

ATATATATATATATACACATATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGTGTGTATATATATATATATGTATATATGTGTGTGTGTATATGTATGTATATATATATGTATGTATATATATATATATATATATATATATATATATATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAATGTTTGTATAGATTTGAATACAGCTAAGCTCTAGGTTGAGGTCTGTGCATGGAAATTATTTGTGGTCCTGCTACGGTGTTATTTAAATGTGTTATTATGACTGTTCAGTTTATAGCATAATTGCTAATGCTACTTAACTTGTAGTTATTCCATTCTTTAGCTGCAGGAATCCCAGATTTCCGCTCTCCTGGCACGGGCTTATA[T/A]GCAAATCTGCAGAAGTACAACCTGCCTTACCCAGAGGCCATCTTTCAGATAGACTATTTCAAGGTCTGATTGTGATTCTGACAAAAAAGCTTATTTTTAATAGTCTTATGTTGATGTCTAAGCATGTTTTAAATTCTTACTTTCCAGAAACATCCGGAGCCCTTCTTTGCTCTGGCCAGAGAACTGTACCCAGGACAGTTTAAGGTAGTTTATCAATCTTATCTGACGTGCATTGTTCAACAATGAAATTTGATGAATCCTAGCACAGTGGAGGAACTTTTTAAATCAACAGTTAACTGGCATTTTTAAAAAGTGAAAAAAAAGTCTCTACATTATACAACTGTTCTGTGTGGTTCTCAAATCTGATTGGCGGATATATAAGCCGAAACACTGGCCTGTTTAGTGTTGAGGTTTCATGGCTTAATTTAACAAGCCTGGTGGCCAGTCTTCATTTATTGCACGTTTCACCAGTAAGAGCACAGTTCAAAACAGGACAAACT

Associated Phenotype:

Not determined