ZMP

ptplb

Ensembl ID:

ENSDARG00000014806

ZFIN ID:

ZDB-GENE-030131-6053

Description:

protein-tyrosine phosphatase-like member B [Source:RefSeq peptide;Acc:NP_956155]

Human Orthologue:

PTPLB

Human Description:

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b [Source:HGNC Sym

Mouse Orthologue:

Ptplb

Mouse Description:

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b Gene [Source:MGI

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa41481	Nonsense	Mutation detected in F1 DNA	Not yet available
sa13302	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa41481

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000015532	Nonsense	116	239	5	7
ENSDART00000133998	Nonsense	121	244	5	7
ENSDART00000134574	Nonsense	50	173	3	5
ENSDART00000141998	Nonsense	117	216	5	6

Genomic Location (Zv9):

Chromosome 9 (position 39085985)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	38223881
GRCz11	9	38033676

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GCTCTATGTAGTCTCTGGGTGACTTAAATCTCTCATTTCAGGTCCAGAGT[G/T]AAGACAGTGTTCTCCTCTTTGTGGTGGCCTGGACAGTCACTGAGATCATC

Long Flanking Sequence:

TAAATTGTACAGTGGTCAACAGTGTTATTTATTGCAATCACTTTTTGCAAACTTCTTTGAAACTAAGAATCAAGTTTTTATTGTCTATCCCAGAGGAAGAAGTCTGAGCTGAAGTGTATAGCTCTGTAAGTTATTTCTACAAGAAACCTGCCTGAATCCAAACTGGAGAGTAATACTAATATACAAAGTGTCCGTGTGTGCCTGTGTATGTTTCTGTTGCTAAAACAACCAAACTACTTTTTAAGCCTGTACATGTGTAGAGGTAATACCGAAACCAGTTTTTTTTTTTTTTTTTTTTTTTTGCTGGGCCTTAATGCATTTTAAAGTGCTTCCGTTGCCGATGCTCTCAGTTGTCCATCTTTGTGTGCCGAGTGGCTTCAGTGAATGGTGATTAAACAATAGCAGACATAACCGCATGGTCCTCTACTACATTTTCTGGCATGCACAGGAGCTCTATGTAGTCTCTGGGTGACTTAAATCTCTCATTTCAGGTCCAGAGT[G/T]AAGACAGTGTTCTCCTCTTTGTGGTGGCCTGGACAGTCACTGAGATCATCCGATACTCTTTCTACACCTTCAGCCTGCTCAACCACCTGCCTTACCTTATCAAATGGGCAAGGTGACTGGCTTTTTTGACTAACATTCACATTTATTCATTCATTCAAAGCAAATTAGGAAAAAAGGACAAGGGCAAGTCAATTAACAGAAACGGACAGTGTGTTTTAATATGCTTTAATTTTTTCACAGGTACACATTTTTTATTGTGCTGTACCCGATGGGAGTGATGGGGGAACTTTTAACAATCTACGCCGCACTGCCATATGTGCAGAAAGCAGGGCTTTACTCCATCACCTTGCCTAACAAGTACAACTTCTCATTCGACTACCACACGTTCCTCATCTTCGTCATGATCTCCTACATACCCTGTACGTATTAACTTGTGCACTAAGACATCACGGGCCAGATTTATTGAAAAAGGGCAATGTAGTGCGAGGTAACGATGCGAG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa13302

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000015532	Essential Splice Site	213	239	None	7
ENSDART00000133998	Essential Splice Site	218	244	None	7
ENSDART00000134574	Essential Splice Site	147	173	None	5
ENSDART00000141998	None	214	216	6	6

Genomic Location (Zv9):

Chromosome 9 (position 39085564)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	38223460
GRCz11	9	38033255

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TTCGACTACCACACGTTCCTCATCTTCGTCAKGATCTCCTACATACCCTG[T/C]ACGTATTAACTTGTGCWCTAAGWCATCACGGGCCAGATTTAYTGAAAWAG

Long Flanking Sequence:

CTCTACTACATTTTCTGGCATGCACAGGAGCTCTATGTAGTCTCTGGGTGACTTAAATCTCTCATTTCAGGTCCAGAGTGAAGACAGTGTTCTCCTCTTTGTGGTGGCCTGGACAGTCACTGAGATCATCCGATACTCTTTCTACACCTTCAGCCTGCTCAACCACCTGCCTTACCTTATCAAATGGGCAAGGTGACTGGCTTTTTTGACTAACATTCACATTTATTCATTCATTCAAAGCAAATTAGGAAAAAAGGACAAGGGCAAGTCAATTAACAGAAACGGACAGTGTGTTTTAATATGCTTTAATTTTTTCACAGGTACACATTTTTTATTGTGCTGTACCCGATGGGAGTGATGGGGGAACTTTTAACAATCTACGCCGCACTGCCATATGTGCAGAAAGCAGGGCTTTACTCCATCACCTTGCCTAACAAGTACAACTTCTCATTCGACTACCACACGTTCCTCATCTTCGTCATGATCTCCTACATACCCTG[T/C]ACGTATTAACTTGTGCACTAAGACATCACGGGCCAGATTTATTGAAAAAGGGCAATGTAGTGCGAGGTAACGATGCGAGAATTTAAACTCAGAAACGTGTCATTGGCGACACCAGTGGACATTGAGTGAATTGCAGCAAGTGTCTTTGTTTGGAAATTGCGCTTGTACACTCATCACTTACTTTGTTTGATGACCTGATACTGATAACAAATGTTCATAGAGCATCCACGCTTCTCAAAATGAAGTTTAGATGTGTGTACAGTAGCAGAGAGAGCACAAACGTGCTGTAAGTTAAAAAAATACATGCAAATATAGAAAAACATTTACTAACATCTCATAGTTTTTTTTGACAACACATGCATGCGTAAATGAGCTACATCGCATGAGTAGCAGTGTGATGTGGCTGTATATCAGCACTGGAGGGAGGCGTGCGTTGACACTAGGCTGTGGGCTAAGTGCCTTGGTGTCCCACCAGTGACGATATACAGCCGTATCGCACT

Associated Phenotype:

Not determined