ZMP

TYK2

Ensembl ID:

ENSDARG00000020326

Description:

tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]

Human Orthologue:

TYK2

Human Description:

tyrosine kinase 2 [Source:HGNC Symbol;Acc:12440]

Mouse Orthologue:

Tyk2

Mouse Description:

tyrosine kinase 2 Gene [Source:MGI Symbol;Acc:MGI:1929470]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa31356	Essential Splice Site	Available for shipment	Available now
sa13280	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa31356

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000055124	Essential Splice Site	67	1174	2	25

Genomic Location (Zv9):

Chromosome 3 (position 46532054)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	48541607
GRCz11	3	46493941

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AATAAGTAAATAAATAAATAAAGATATCTAAAATGCTTTCTCTTTTCCTC[A/T]GGGATCACTCCAGTCTGTCATGCCTTGTTTGCACTGTATGACCCTGCTTC

Long Flanking Sequence:

TTTTCACATTCATATCCCTTTAAGGACATTGTGACGCTACAATCAAGTTCAGACGCAGTGTTTATTGCAATATAGAATAACTTCCTCAGAATGGGACTTTGTAACTTCACAGCATTCAAGGAAGTGTAAAGTGTTAAAAAGTTTTAAAAGACTGTCCCCCCCCCCCACAGTTTTATTGTAAACACACCTTAATGTCATTGACCCAGGTGCTGGACTCAATGTATGATGTATAGACGAGGACGTTCTAGGAGATCAAAGAAAGCAGGGACGTCCAAAGGACAGAGTGAAGGTCCTGGTGTCCATGTGTTTCTGTTCTGGACCAAAGATGGAGAACGATGCCTGTCTTACAAGAAGGGTGAGGTGACTGCTGAAGATCTCACCACTGAAGCAGCAAAGGCTGTGGGTAGGTTTGGGTGTGGATGCCAGTAAGAGATTTAAAATCAATAAATAAATAAGTAAATAAATAAATAAAGATATCTAAAATGCTTTCTCTTTTCCTC[A/T]GGGATCACTCCAGTCTGTCATGCCTTGTTTGCACTGTATGACCCTGCTTCATTGTGCTGGTACAGTCCAAATCACAACTTTAATGCAGAGAACCAGTCGGGCCTGTTACTGCATTTTCGTTTGAGGTGAGTGTGAAGGCGTGTAGAGATTGTTGGATTGGTATGCGTGCATAAAAGCGTGATGCGACAGTGAAAGAAAGCTGTAATCATCAATGGAAACTCTTTTGTAGATTTTACTTTCATAAGTGGCATGGATTAGGTGAAAATGCACCAGAAGTGGGCCGCTATGCATTACGGACCTCAGCTGGGACACAGCAGGCGACATCTCATTTGCTGGAGCTGAGTGCCCTGGAATACCTGTTTGCTCAGGTGATTTTTTTTTTACAGTCTCTCAAAGTAATTCAAAGAGGTTTCCTGAAACCCTTTAGTTTCATTGCCTTCATTTCTTTGTTGTTTGAAGAGAAAACATTGCAGCGTCTGAACAGGTTCAGGCTATTTAAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa13280

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000055124	Essential Splice Site	757	1174	14	25

Genomic Location (Zv9):

Chromosome 3 (position 46562910)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	48572463
GRCz11	3	46524797

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TGTAAAGCTCAGTGACCCAGGCATTTCTCTGTCAGCTCTATCTCAAGGAG[G/A]TAAGCTCGTGTTGTTATTCTCACGTGCTCTAGATCGAATCGAGCACATCC

Long Flanking Sequence:

TGGCGCATCAAGCACCGCCGTCGCCGCGGCATGAATGGCGGTACAAGGAACACATTGAAGTAGTAACATCTGTATGTGGTTAATTTGTGATTAATTTGATTAACCGCCACACTGTGTGACTAATTACATTTAATATTTTAATCGCACAAGCCAAACATGAGCACAACATCTTCTCACTTCTGTAATGTGAAACAATACATTTAATCAGTAAAGTAAACTAATTCACAAATATCTCTGATGTTACATTTTAAAATCAAAAGAATTTCTGATTTTAACACATGTTGTTTACATTAGGAGAACTACATTTAATGTTATTGTCAGCTGCATCATTAAAAACAACTACCATCATATATGTGCTTTGCAGGAGACCAAGCGTTTAGTGCATGGAAATGTCTGTGGCAAGAACATCCTGGTGGTCCGGAAAGGTTTAGAGGAGGGCACGTCTCCTTTTGTAAAGCTCAGTGACCCAGGCATTTCTCTGTCAGCTCTATCTCAAGGAG[G/A]TAAGCTCGTGTTGTTATTCTCACGTGCTCTAGATCGAATCGAGCACATCCTGTACCCCATCTCTGTATCATTTCTCTAGTTACCTCTCTACTATTTACTTCATCAGGTTCTCTCGTGGTTGAGAGAACAGGAAGCCAACCACTTCCTCATAGTGATGTTTGCTTCCTTTAGATCATATTTACAGCAGTGAAGCAGCTGTCCAGAGAACATAAATAATAAATAAGTCATGAATGTTGTGCCGTTCTTTGAGGTCAACCTATAATATTATCAAGGTCTTTACAACAAAAAGATGATAAGCATCTCAATAATAAGCAGTAATAAGCTGTATTATGTCTTCTTTGGACCTCCTCATCAGAATTCATGTTTGAATAGACATAGCAGATTATAGATTTGAAAGTAAACCAATAGTATCTGGATTGGATGCAGACTTGGATTTGCAACCTGAGACTGCATATTTCAGAGATGCAATGTCTGACACAATGCACTCAATGCATCTGGTG

Associated Phenotype:

Not determined