ZMP
apba2
Ensembl ID:
ZFIN ID:
Human Orthologue:
APBA2
Human Description:
amyloid beta (A4) precursor protein-binding, family A, member 2 [Source:HGNC Symbol;Acc:579]
Mouse Orthologue:
Apba2
Mouse Description:
amyloid beta (A4) precursor protein-binding, family A, member 2 Gene [Source:MGI Symbol;Acc:MGI:1261
Alleles
There are 7 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa34095 | Nonsense | Available for shipment | Available now |
| sa20981 | Nonsense | Available for shipment | Available now |
| sa40922 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa11600 | Essential Splice Site | Available for shipment | Available now |
| sa17752 | Essential Splice Site | Available for shipment | Available now |
| sa13279 | Essential Splice Site | Available for shipment | Available now |
| sa44668 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa34095
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085661 | Nonsense | 55 | 796 | 1 | 13 |
Genomic Location (Zv9):
Chromosome 7 (position 32203671)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 30596013 |
| GRCz11 | 7 | 30867163 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGGAGGAGTATGAAGAGCACCATGACCCCGAGGTGACCCAACACTCTTA[C/A]CACAACCAAGAAGAGGCAGATTTGACAGACAGCCGACCGACTACGCCCAC
Long Flanking Sequence:
TCAGGCTCGATTTTCAATCACTTGAATTAATTTGGATATCCCTACTAAGTATGCTAATAAATACTCGTTTTTTAAACCCTGTTAACCTACAATGCCCTAAAGTAAAGTGATTTTTAAACACGTTTACCACATTTGTTTTAACTTACCATTGTAAACATCATGTTTTACCATGTAAATGTCTAGCTGTATGTGCGTCTTCCTAACTATCAGTGTTTCCTTCTCTTACTAAACTGACTGTTTTTATTGAGTATAAATTGTGAAAAATGCTGTCATACTTACTATACATCTGTCTTTGTTTGATAGGACTGAGGTTTCCAGTGATGATCGTCCTGTGAGTGCTTCTCAATGGCTCAGAGGAAGAGGCCAGGGATCAACAGCGGCATGGCCACAGAGCCTCATGCTCCAGCTCCACGCTCCTGTCCAGCCCCGTACCCTGACCCTGAGCACCCTGAGGAGGAGTATGAAGAGCACCATGACCCCGAGGTGACCCAACACTCTTA[C/A]CACAACCAAGAAGAGGCAGATTTGACAGACAGCCGACCGACTACGCCCACAACTCCCGACCACGCCCACAGAGACTACCACAGCCACCCGGACAGTCTGGACGGAGACTCCAGCTCAGACTATGTCAATAACACATCAGATGAGGAAGAGGATGACTTTGATGAGGGGCTTCCAGAGGAGGATGAAGGTGTGACATATTATATACGCTATTGCCCAGAGGATGACAGCTATCTGGAGGGAATGGACTGCAACGATCCTGAATATGTACACCCTGATGGTCGCATGGAGCCACCTCCGGACACAGACGAGTGCCAGGAAGCAGTAGAGGAATGGGTGGAGGGAGAGGACGATGCACAGGGTGATGAAGATGATGATGATGAGGAGGAGGATGATGACGATGATGATGGAGAGGTACGTTGCGAAGTACTCGAGCAGGACTCTGATCAGCAGCTTTATGATGGCAGACCTGAACCTGTCCTTGATCACCACCACCATCAACA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20981
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085661 | Nonsense | 94 | 796 | 1 | 13 |
Genomic Location (Zv9):
Chromosome 7 (position 32203787)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 30596129 |
| GRCz11 | 7 | 30867279 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCACAGAGACTACCACAGCCACCCGGACAGTCTGGACGGAGACTCCAGCT[C/A]AGACTATGTCAATAACACATCAGATGAGGAAGAGGATGACTTTGATGAGG
Long Flanking Sequence:
AACACGTTTACCACATTTGTTTTAACTTACCATTGTAAACATCATGTTTTACCATGTAAATGTCTAGCTGTATGTGCGTCTTCCTAACTATCAGTGTTTCCTTCTCTTACTAAACTGACTGTTTTTATTGAGTATAAATTGTGAAAAATGCTGTCATACTTACTATACATCTGTCTTTGTTTGATAGGACTGAGGTTTCCAGTGATGATCGTCCTGTGAGTGCTTCTCAATGGCTCAGAGGAAGAGGCCAGGGATCAACAGCGGCATGGCCACAGAGCCTCATGCTCCAGCTCCACGCTCCTGTCCAGCCCCGTACCCTGACCCTGAGCACCCTGAGGAGGAGTATGAAGAGCACCATGACCCCGAGGTGACCCAACACTCTTACCACAACCAAGAAGAGGCAGATTTGACAGACAGCCGACCGACTACGCCCACAACTCCCGACCACGCCCACAGAGACTACCACAGCCACCCGGACAGTCTGGACGGAGACTCCAGCT[C/A]AGACTATGTCAATAACACATCAGATGAGGAAGAGGATGACTTTGATGAGGGGCTTCCAGAGGAGGATGAAGGTGTGACATATTATATACGCTATTGCCCAGAGGATGACAGCTATCTGGAGGGAATGGACTGCAACGATCCTGAATATGTACACCCTGATGGTCGCATGGAGCCACCTCCGGACACAGACGAGTGCCAGGAAGCAGTAGAGGAATGGGTGGAGGGAGAGGACGATGCACAGGGTGATGAAGATGATGATGATGAGGAGGAGGATGATGACGATGATGATGGAGAGGTACGTTGCGAAGTACTCGAGCAGGACTCTGATCAGCAGCTTTATGATGGCAGACCTGAACCTGTCCTTGATCACCACCACCATCAACACTATACAGATCCCCATCAGGAGCAGCTTCCCCCTCCCATTGAAGATCAGGAGGTGAAGGATGTTGAGAGCAGTGAAAGGTACTGTCCCGATCAGGAGGAAGAACCACAGGTTGGAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40922
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085661 | Essential Splice Site | 452 | 796 | 5 | 13 |
Genomic Location (Zv9):
Chromosome 7 (position 32215781)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 30608123 |
| GRCz11 | 7 | 30879273 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAAAAACATCCGGATGATGCAGGCCCAGGAGGCAGTGAGCAGGGTCAAGG[T/G]ACGAAACCCAAGGACCTCAATATTTCCATTTGATTTCAGTGTGGAGTTCA
Long Flanking Sequence:
TTCTGGTTTACGCAAAAAGGATAGATTTCTGTCACACTTAGAATTAGAATGATGGCATAAGGGATTCCTTGGAGGGTTTTATGACGTCCACATTTCCATTTCGCACAAGCAGAATAATCCCAAGCAACACACCCTGCTTTTTCTCATACTCCAGCTTTTCAGTGTCCACAGTATAATTTTATCAGGATTGGACTGAGAACACACATTTATACACTCCACATCTCCATGCAACTTTTCAGCCTGATAAGCTCACGCTCATATACCTTATCTGTCACTGTGAGGTGGTCCATAGAGGAGGTGGCAACACAACAAATAGCTTTAATAATGAATTCTTGATGCTTTCCCTCTAACAGTGCCGGGCCCCTGTGAGCCCGAGGACCTCATTGATGGGATTATCTTTGCCGCCAACTACCTCGGCTCCACTCAGCTCCTGTCGGAGAGAAATCCATCCAAAAACATCCGGATGATGCAGGCCCAGGAGGCAGTGAGCAGGGTCAAGG[T/G]ACGAAACCCAAGGACCTCAATATTTCCATTTGATTTCAGTGTGGAGTTCAAGCGACAACATTTGGATGAAGCGGATGCAGATTTCTCTGTGGAAAATTAGATGAGAGGAGATTTGTTTGTTTACACCCCAGGACTTGTTGACTAATCAGTAGTTATAGGATTATTTTCCCCGGTGTAGGAGTGTAATCCCTCTCCCTCTCAATTGGTTAATGTAGAAAGCACTCCTGCTGCCATGTTACATGGAAAATTTAAAGAGAATTATTGTGTTTTAAGAGAGCATGTGGTGCAGTCAAAGTACTTTTTTCCCCAAAACGCTTTGGATGCTGACCCTCTCCGCAGCAGTTTATGGGTAGACAGAAACAAAATCAGCTCTGTAAACATGCCAATATATTTATGGCCTTTCTTTTTCTTGCATTAGCGGTAGGGGTAGGGGTGTGTAATGAGCATTATCCACAATAATATTACTTTGAACAATGCACAAAGTAATATAAATCACACAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa11600
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085661 | Essential Splice Site | 686 | 796 | 10 | 13 |
Genomic Location (Zv9):
Chromosome 7 (position 32245868)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 30638210 |
| GRCz11 | 7 | 30909360 |
KASP Assay ID:
2259-9012.1 (used for ordering genotyping assays)
KASP Sequence:
CACCAGCCTGGTGGGGCTTCCTCTCGCCACCTGTCAGGGAATCATCAAGG[T/A]GTGCTACTAGGRTTTGGGCTGTCTGTCTGAACACCGGCCAGRAATCCATC
Long Flanking Sequence:
TAGGCCTGTAATTTGTACAAAAACAAAGGTCATTGACAAAAATAAACTTGTTAATGACTAAGTTTTTTACCAAAATGTTACATTTATAAAAAAACAAAACTAATTTCTAACTTCTTTGGAACACATACAGGACACACGGGGGCAAGTTGATGCTATTTTGAACCCTCAAGCTGTCAGTCTCATGTTATCAACTTAGTAAAATTCTTCTCTTAATTGCTTTTTTCTTTTATGGCCTTTTATTGGCAATCTGCTGTAATCCCTCATGTGTCTCTCTCTCCTCCCACAGCTGCAGCTGGAGAAGCAGAAGGGGGAGATTCTGGGCATAGTGATTGTGGAGTCTGGCTGGGGCTCCATCCTGCCCACAGTCATCCTGGCCAACATGATGAATGGAGGCCCTGCCGCCCGTTCTGGGAAGCTCAGCATCGGTGACCAGATCATGTCAATCAACAACACCAGCCTGGTGGGGCTTCCTCTCGCCACCTGTCAGGGAATCATCAAGG[T/A]GTGCTACTAGGGTTTGGGCTGTCTGTCTGAACACCGGCCAGAAATCCATCTGTGCTATTCTGAGTAGCTGCTTATTAAACCCTAAAACGCAGGTTTTGGAGATGTTAACAGATATGTAATTTATAGGTGGCACATTGCTGAAAACAGTACATTTTATTATCAAGTGGATTGTTTTGTGTTTTTTTGAGCCAATAAATGTTTCTTTTAAGTTAAAGGTAAAATATGATGTATGGTGATTAGTCGCCAGGACTGGAGAGTACATTTACAAGTCATCTGATTTTGACAATTTCCCCGCATTTATTAATGAGAAATAGCTATTTTGATCAAGGTCTTGCTTAGTATTAAAAATAAGATATCATTTCATTACTATGCATGATAATGTATATGTTCTGTCTCCTTTATCAGAACTTTCAGAACACTTCAATTCAGAAGTTTGCACGGGGTTCAAGACACTTTAAATCACTGATATACTTGAAACGATATTATAGAATGAACTGAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa17752
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085661 | Essential Splice Site | 726 | 796 | 11 | 13 |
| ENSDART00000085661 | Essential Splice Site | 726 | 796 | 11 | 13 |
Genomic Location (Zv9):
Chromosome 7 (position 32248230)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 30640572 |
| GRCz11 | 7 | 30911722 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAGGCCAGACCTCAAGTACCAGCTGGGMTTCAGTGTGCAGAAWGGCATT[G/A]TGAGTATGGAAGAACTCRRAAATGTTGAGATGAGTTGATGAGTTTTATYG
Long Flanking Sequence:
TAGAAAAAGGGGCACTGCGGGCAGCGAGTAAACAAAAGCTGAATATACAGCGGGAGCAGGCAGAAGCGGGACTAAAAATTCAACCCCGCGCAGATTTTATTTTGTTCGGTGTGCATCAGGCCGGAAAAAGCCACAAAACTGTTCTTCTCTCACAGCCGCCATTGCAACCTCACTTACAATATAGTCTCACAGTGTAGGTCACTCTTACTTCTTTTTGCCCTCAAATGAAGAATGAAAAAGAATAACAGGACACTTGACAATTAATGAAGTGACTGCAAAGGCAATGCAATCTTAAATTTCTGTTGTTATGATCCCACTGTAATAATGCAGTGCAGTTGTGATTGTACTGAGCTACTGTATGTTTGGTTTATTTTCATCAGGGCCTGAAAAATCAGGTGCAGGTGAAGCTGAACATTGTGAGCTGCCCTCCTGTGACCACAGTTCTCATTAAGAGGCCAGACCTCAAGTACCAGCTGGGATTCAGTGTGCAGAATGGCATT[G/A]TGAGTATGGAAGAACTCGGAAATGTTGAGATGAGTTGATGAGTTTTATCGTTCTGAGTTTATGTTTTGTCTGGTCTTCCTCAGATCTGCAGTTTGATGCGAGGAGGGATCGCGGAGAGAGGAGGTGTGCGGGTCGGTCATCGTATTATTGAGATAAATGGCCAAAGTGTTGTGGCCACAGCACATGAGAAGATTGTCCAAGCTCTGTCCAATTCCGTCGGCGAGGTAAGCCCTACCGTTCAATTTATTTGGGGTCTTGAAAGTTAAGGATTCAAGAAAGATATTAAAAAAATTACTTTATTCTCAGGAAGGCTGATTATTTTAAAATATTTAAAAATGTAATATACTCCTGTGAAGGCAACAAAGTAACTTCCACAGAAATCCAACTGAATAAACTAGAAGATGAGAAACACTGGATTAAAGAGGTTCTACATTGCATCTATCTTAAGAAACTGAGGCATTGTTTTAAAGGATCACTCAACTCCTTTAATGTCCCATACT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa13279
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085661 | Essential Splice Site | 726 | 796 | 11 | 13 |
| ENSDART00000085661 | Essential Splice Site | 726 | 796 | 11 | 13 |
Genomic Location (Zv9):
Chromosome 7 (position 32248230)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 30640572 |
| GRCz11 | 7 | 30911722 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAGGCCAGACCTCAAGTACCAGCTGGGMTTCAGTGTGCAGAAWGGCATT[G/T]TGAGTATGGAAGAACTCRRAAATGTTGAGATGAGTTGATGAGTTTTATYG
Long Flanking Sequence:
TAGAAAAAGGGGCACTGCGGGCAGCGAGTAAACAAAAGCTGAATATACAGCGGGAGCAGGCAGAAGCGGGACTAAAAATTCAACCCCGCGCAGATTTTATTTTGTTCGGTGTGCATCAGGCCGGAAAAAGCCACAAAACTGTTCTTCTCTCACAGCCGCCATTGCAACCTCACTTACAATATAGTCTCACAGTGTAGGTCACTCTTACTTCTTTTTGCCCTCAAATGAAGAATGAAAAAGAATAACAGGACACTTGACAATTAATGAAGTGACTGCAAAGGCAATGCAATCTTAAATTTCTGTTGTTATGATCCCACTGTAATAATGCAGTGCAGTTGTGATTGTACTGAGCTACTGTATGTTTGGTTTATTTTCATCAGGGCCTGAAAAATCAGGTGCAGGTGAAGCTGAACATTGTGAGCTGCCCTCCTGTGACCACAGTTCTCATTAAGAGGCCAGACCTCAAGTACCAGCTGGGATTCAGTGTGCAGAATGGCATT[G/T]TGAGTATGGAAGAACTCGGAAATGTTGAGATGAGTTGATGAGTTTTATCGTTCTGAGTTTATGTTTTGTCTGGTCTTCCTCAGATCTGCAGTTTGATGCGAGGAGGGATCGCGGAGAGAGGAGGTGTGCGGGTCGGTCATCGTATTATTGAGATAAATGGCCAAAGTGTTGTGGCCACAGCACATGAGAAGATTGTCCAAGCTCTGTCCAATTCCGTCGGCGAGGTAAGCCCTACCGTTCAATTTATTTGGGGTCTTGAAAGTTAAGGATTCAAGAAAGATATTAAAAAAATTACTTTATTCTCAGGAAGGCTGATTATTTTAAAATATTTAAAAATGTAATATACTCCTGTGAAGGCAACAAAGTAACTTCCACAGAAATCCAACTGAATAAACTAGAAGATGAGAAACACTGGATTAAAGAGGTTCTACATTGCATCTATCTTAAGAAACTGAGGCATTGTTTTAAAGGATCACTCAACTCCTTTAATGTCCCATACT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa44668
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000085661 | Essential Splice Site | 773 | 796 | 12 | 13 |
Genomic Location (Zv9):
Chromosome 7 (position 32248456)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 30640798 |
| GRCz11 | 7 | 30911948 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAGCACATGAGAAGATTGTCCAAGCTCTGTCCAATTCCGTCGGCGAGG[T/C]AAGCCCTACCGTTCAATTTATTTGGGGTCTTGAAAGTTAAGGATTCAAGA
Long Flanking Sequence:
GAAGAATGAAAAAGAATAACAGGACACTTGACAATTAATGAAGTGACTGCAAAGGCAATGCAATCTTAAATTTCTGTTGTTATGATCCCACTGTAATAATGCAGTGCAGTTGTGATTGTACTGAGCTACTGTATGTTTGGTTTATTTTCATCAGGGCCTGAAAAATCAGGTGCAGGTGAAGCTGAACATTGTGAGCTGCCCTCCTGTGACCACAGTTCTCATTAAGAGGCCAGACCTCAAGTACCAGCTGGGATTCAGTGTGCAGAATGGCATTGTGAGTATGGAAGAACTCGGAAATGTTGAGATGAGTTGATGAGTTTTATCGTTCTGAGTTTATGTTTTGTCTGGTCTTCCTCAGATCTGCAGTTTGATGCGAGGAGGGATCGCGGAGAGAGGAGGTGTGCGGGTCGGTCATCGTATTATTGAGATAAATGGCCAAAGTGTTGTGGCCACAGCACATGAGAAGATTGTCCAAGCTCTGTCCAATTCCGTCGGCGAGG[T/C]AAGCCCTACCGTTCAATTTATTTGGGGTCTTGAAAGTTAAGGATTCAAGAAAGATATTAAAAAAATTACTTTATTCTCAGGAAGGCTGATTATTTTAAAATATTTAAAAATGTAATATACTCCTGTGAAGGCAACAAAGTAACTTCCACAGAAATCCAACTGAATAAACTAGAAGATGAGAAACACTGGATTAAAGAGGTTCTACATTGCATCTATCTTAAGAAACTGAGGCATTGTTTTAAAGGATCACTCAACTCCTTTAATGTCCCATACTGTCTGTCATTGAGAACCTTAATATTTCAGGACCTGCTGGCTAGAATTTCAAAAAGGAAAAAGAGAGACTTTTAGTATTTACTTTACAGTACATCTTCTTCTTCTATATTTACCCATATATTTATTATATCTTTTTATTTAATTAATTAATGTATTTAATTGTAATTTTTTCAATTGGTTTATTTTTTTATCTGTGTCTTGACTCATCTTTGCATACTTATTAAAGG
Associated Phenotype:
Not determined