Busch Lab

ZMP

si:dkey-106l3.5

Ensembl ID:
ENSDARG00000078105
ZFIN ID:
ZDB-GENE-091204-356
Human Orthologue:
DEPDC5
Human Description:
DEP domain containing 5 [Source:HGNC Symbol;Acc:18423]
Mouse Orthologue:
Depdc5
Mouse Description:
DEP domain containing 5 Gene [Source:MGI Symbol;Acc:MGI:2141101]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa1323 Essential Splice Site Available for shipment Available now
sa21700 Nonsense Available for shipment Available now
sa9750 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa1323
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111088 Essential Splice Site 121 1604 5 44
ENSDART00000131751 None None 266 None 7
ENSDART00000134059 Essential Splice Site 125 1568 5 41
ENSDART00000138777 None None 149 None 5

The following transcripts of ENSDARG00000078105 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 16931419)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 17261667
GRCz11 10 17219631
KASP Assay ID:
554-1237.1 (used for ordering genotyping assays)
KASP Sequence:
AGATCAGTATATTGGGCGAGGAGACATGTGGCGACTAAAGAAGAGCTTAG[T/C]GAGTAGATAAAGTAGAAATCTGCATCTTTGTTCATTTTTTGTTGACTAAC
Long Flanking Sequence:
GTATGTTTTATTAAAAGTACCTAATTAAAAGCACATTGCGACTACTGACATTTAATAATCCCCATTAATATCATAATAATTATATCATATATTTAAACGACAGATTCAGTTAATGATTTTGTCTCTTTATAAAACCTTCTTTGCCCAAAACTAAAACAAACAACAAACAAAAATCTATCGTAAACTTTCAGTTTAAACCATTTTGGTCTTTCCTAAGAATAATGTCTTTTATCCACTGACAGAAACTATCAGTGTCGATCAGACTGTGGCTCAGGCTTTCAAGCTGCGTGCCTACCAAGACGTCATCATCAATATTGTGGATCCAAAGGTATTTCATACTGAAATATTAAATTATTAAATGGTTGGAGACAATATTTACCACCTAATGTCTTAATGCTCTATTGAAATTGAAAAGGAGGTGACTTTGGATCTGGTGGAGCTCACCTTTAAAGATCAGTATATTGGGCGAGGAGACATGTGGCGACTAAAGAAGAGCTTAG[T/C]GAGTAGATAAAGTAGAAATCTGCATCTTTGTTCATTTTTTGTTGACTAACATTGATCCTGATGTCTCTGTTTTGTTGTTTCAGGTGAGCACATGTGCATATGTGACACAGAAAGTAGAGTTTGCAGGAATCAGGTAACAACATCTACTAAGAAATAAATACTGTCTGGAATACTGGATTATGATTGGTTAATTTAAGTATTCTAATGTTAGAAGTATTGATATAATGACTTTTTATTATGTCAAATGTAACATGCACTACTGTTCAAAAGTTTGGGGCAGTAAGATTCTTTTAAAAAAATTAAGGATGTAAAATATATAGATGTATATATATTCCTAACTCATTAAATTTATCATATGTGACAGTAAAAATATTTATGACATGATTAATGATTTCTATTCATTTACGAGTCCTGTATTAAAAATGATTGAGCATCAGATTGACATATTATGCTAATTTCTGAAGGGTCATGTGACACTAATTTTAGTTGCTGATGATTCT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa21700
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111088 Nonsense 922 1604 28 44
ENSDART00000131751 None None 266 None 7
ENSDART00000134059 Nonsense 909 1568 28 41
ENSDART00000138777 None None 149 None 5

The following transcripts of ENSDARG00000078105 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 16958874)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 17234212
GRCz11 10 17192176
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACGAGCGGCTGGAGGAGTACAAGTGGAACTATTTAGACCAGTACATCTG[C/A]TCTGCCGGATCAGAGGACTTCAGGTAAGTAGTGTTATTCAGTTCACACCA
Long Flanking Sequence:
AGCAGTCCCCTGTATTCCAGAGGTACATCACCTGCTGGAGGCCCTTAGATATGAACACTAGCTGCATTTTGTCTTCCTGTTATGAACTATGCTTCAATATAATGCAGGTGAAAGAATTAAAGGTGTGCTTTTCAGGGCTGGTGTCTCGCCGTAAACCAGAAGAAGAAGAGAGTCTTTACTGGCTCAGTATGGGCAGAACTTTTCATAAAGTCTGTCTTAAAGATAAGATCATCACAGTCACCCGCTACCTCCCAAAGTCAGTTGATGTTTTTATTCATTCAGATTCAGATCATGTCATTTGCTCTTCTATACATGAATTGTGTGTGTGTGCATTTTTATTTTTGGTTCATCTTTAGGTATCCATATGAATCAACACAGATTCAGTACAGCTACAATCTGTGCCCTCCACATGCAGATGCCCACTTCATGCCATTCTGGGTAGAGTTCAGCCACGAGCGGCTGGAGGAGTACAAGTGGAACTATTTAGACCAGTACATCTG[C/A]TCTGCCGGATCAGAGGACTTCAGGTAAGTAGTGTTATTCAGTTCACACCATGGCACTGACACAAAACCTATACAGGTCCACAATAGGGTTGGGTACCATACCAATATTCTTAGACTGAATCACATTTTTTTTCACTTTATCTCAAAAAACATCTACAAACACACAAACTCCAAAAAACAATGTAGTGTACATGCCAAACCGGTGTGTGGTGTTGTAATTATCCTACAGAGATGCTCAAAAATGGAGAAGAAGAATTGAAGCATGCACATATGCACACATTACTCACTATTACCTACATTAGTCCACTAATATAGTCTTCTTGAAGGGGTGAATAAATTCAGTGAGGGAATTCGTGCACTGAAAAGAATACCGTTTTCTTTGTGTTTTGCTGCTTGACGAATCTTTCAGATTAATTAGATTTTCATCTTCTTGGTCAGACCCTGTAATAGTTATTCAACACTTAGTGAGCTGTCTATTAGTAATGAAACAAAGACTTTTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9750
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111088 Essential Splice Site 1459 1604 None 44
ENSDART00000131751 Essential Splice Site 194 266 None 7
ENSDART00000134059 Essential Splice Site 1423 1568 None 41
ENSDART00000138777 None None 149 None 5

The following transcripts of ENSDARG00000078105 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 16976898)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 17216188
GRCz11 10 17174152
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTAAATATCCAGTGCCTGCTAAAGGAGGGCTCTGATAACCTTTTTGAGGG[T/C]GAGGACACAAGAAGTAATTGTGCAGTTGTTGTAGTCCAAGGGACAGATTC
Long Flanking Sequence:
CTCTGTCTTTTTCGCTGTGTTTTCACCCCTCCCCTCTCAGCCGCCACAGTTCCAGAGCAGAAAACAGTCACCTTGGATGTCGATGTGAACAATCGTAGTGATCGGACAGAATGGTGCAGCTGCTATTACCATGGCAACTTCTCCCTTAATGCTGCCTTTGAAATCAAGCTGCACTGGATGGCCGTCACTGCAGCCGTGCTCTTTGAAATGGTGAGCGTGGGATGAACATATTACCATTTAGAGATAATATTAGGAGGTGCTTGCATTGTTATGCATTGTTGCACAGTAAGTACATGGGTACAGTTCTTATGCATTCTTGTGTTTTAGGTGCAAGGCTGGCACAGGAAGGCAGCATCTTGCGGATTCCTGCTTGTCCCTGTGTTGGAGGTGCCCTTTGCTTTGTCGTCATACCTATATGGCGACCCACTCCGTGCTCAGTTGTTTATTCCCCTAAATATCCAGTGCCTGCTAAAGGAGGGCTCTGATAACCTTTTTGAGGG[T/C]GAGGACACAAGAAGTAATTGTGCAGTTGTTGTAGTCCAAGGGACAGATTCACTTGCAGCAATTTAACCTATTGTTTTTTTTCTTTAAAGCATTGTTTGACTTTCCTTTTCTGATCCTAGTTTATGGGAGAAGAATATTTAAATGCAGTATGATTTACAAGAGATTTGCCAGATTCAGTTTACTGGCATTTTTTTAAATTATTTAATGCCCAAAAAAGCATGTCTGAAAACATGCACATTTCTCAGATTATTGTGAGCTAAGTTTTACATTAGTATATTTATTAGATCAGGGGTTCCCAACCTTTTCAACCCGTGACACCTAAAATAGCAATGCCAGTGACTTGCAACCCCAAATTTCTCAGAGGTGGTTATAAATATACAAAAGTTGCGCACACATCAATAGGCCAATAAAAACATGAACATAGTGCTAACACAAAACATGTGCAACAGTCTAACAACCATTTCAATTTCATAGTCAATTACTAATTTGCTTAATTTAAT
Associated Phenotype:
Not determined