Busch Lab

ZMP

cdk12

Ensembl ID:
ENSDARG00000063726
ZFIN ID:
ZDB-GENE-081104-294
Description:
Novel protein similar to H.sapiens CRKRS, Cdc2-related kinase, arginine/serine-rich (CRKRS) [Source:
Human Orthologue:
CDK12
Human Description:
cyclin-dependent kinase 12 [Source:HGNC Symbol;Acc:24224]
Mouse Orthologue:
Cdk12
Mouse Description:
cyclin-dependent kinase 12 Gene [Source:MGI Symbol;Acc:MGI:1098802]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa1307 Nonsense Available for shipment Available now
sa23419 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa1307
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093402 Nonsense 250 1293 1 14
ENSDART00000143222 Nonsense 102 688 1 7
Genomic Location (Zv9):
Chromosome 19 (position 5482053)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 4941364
GRCz11 19 4857850
KASP Assay ID:
554-1222.1 (used for ordering genotyping assays)
KASP Sequence:
AGYGTGCGTTCATCCAAATCTCGCAAAGAAAAGAGAAGGAACGAGGAGTA[T/A]GAGGAGGMCCGGAGCCATCGAAAGGCCGCAAAGAGTCGCAAGTCTAGCCC
Long Flanking Sequence:
GTGGAGTACGACGACATCAGCTCGGATTCGGACACGTTCCTTGACTCCCCCGCCACCGGGAACCCGGTGGACACCAGAGACGCCGAACAGCTAGATCTGTCGGACTACGGTGAGGTGGTGGCGGGGGTCGCCAAAGAGAACCGGACTCATAAACGCAAGCGCTCCCGGAAGAAATCCAAAGACCGGCATCGGGTCAGGGAGTCTGCGGAAAGACCAGTAGGGGCCAAAAAGAGCATCAAGGACCGGGAGAGGGTGAGCAAAGAGAGCCGAAAGAAGGTTAAGGAGAGGGCTAGTCCAGTCGCGTGCCTTGCTGCTTCATCATCCAGACGCTCCGGTGAGACCGGTGCCAAAAAGCTCGGCGGCGGCGAATCGGTGTCCTCCAGCGCGGTGCAGTCAGCTGTCAGCCTGGGCAGCAGCGCCTCCTCCGCATCTTCCTCCATCAGTAAGGAAAGCGTGCGTTCATCCAAATCTCGCAAAGAAAAGAGAAGGAACGAGGAGTA[T/A]GAGGAGGACCGGAGCCATCGAAAGGCCGCAAAGAGTCGCAAGTCTAGCCCTAAAGGGAAAAGCCAGTCCCGGAGGACCGTGGTGGACAGTCCTTCCGTTGCGGAGCTCGAGAACAGTTACTCCTCCAAACGCAAGGCCGCGAGCCCGAGCCCGTACAGAGAGCCGCCCAGGCGGAGCAGACAGAGGTCCGAGAGCCCCTACGGGAGAAGGAGGTCTTCCAGCCCTGAGAAGGATGGGAGTCCGTATGTGAGCAGAAAACACTCACCTGGAAGTCCTTACGCGAGCAGACGCTCACCCAGCAGCAGTCCAGTGTCCAGGTGTGTGCTCACTACATATTAAACGCACAGTTCACCCTAAAATTATAACGCTGTCATCATTTACTCACCTTTTACTTGTTTCAGGCCTTTGAGTGTCCTTCTTCTGTTAAACACTTAAAAAATAATTTTTGCTGTAACCATTGACTCCCATAGTATCTGTTTTTCCTAACATGGAAGTCTGTG
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa23419
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093402 Essential Splice Site 897 1293 10 14
ENSDART00000143222 None None 688 None 7
Genomic Location (Zv9):
Chromosome 19 (position 5509766)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 4969077
GRCz11 19 4885563
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAAGGGCTTCAGTTGAAATGCTGTTTGTCTTCTTTTCTCCCCCGATCA[G/A]TCGTTTGTGTGGTAGTCCATGTCCTGCTGCTTGGCCAGATGTAATCCGGC
Long Flanking Sequence:
AGATCATTTAAGCGAGCTACGAAGAACAGACCCCTGTTGTTCATATCGCAAAGAAAACAAAATATGCAGTCCTAATTGATACAGTGTGTGTGTGTGTATAATTGTGAGTTGATGTTCTTTTCCAGTCGACCGTACACTAATAAGGTGATCACACTGTGGTATCGCCCGCCTGAGCTGCTACTGGGGGAGGAAAGATACTCACCTGCTATTGATGTCTGGAGCTGCGGGTGAGACAGAAGTCTGATTGCCATCATCTCATTACATTTACACCCAAAGTGATTTAAAATAGTAATATTTTTTTTTTGTGTGTGTGCTTTTGTTTAAAGGTGTATTTTAGGCGAGCTCTTCACTAAGAAACCAATTTTCCAAGCCAACCAAGAGCTTCTCCAGCTTGAGCTGATTAGGTGTGTTTGGATGTGTGTTTTTGTCAGTCTAATGCTGAAGGATGGAGAAAAGGGCTTCAGTTGAAATGCTGTTTGTCTTCTTTTCTCCCCCGATCA[G/A]TCGTTTGTGTGGTAGTCCATGTCCTGCTGCTTGGCCAGATGTAATCCGGCTGCCGTACTTCAATACCATGAGACCCAAGAAACAGTACAGGCGACGCTTACGAGAGGAGTTCTCTTTGTAAGTTCAACCTGATTCCTAAAACACATCCACTGCGAACATAACAGACTGTTCGGTTAATGATGGAGGTTTCTTTGACGAAAAATACCGTAAATTATATATATTGTGATTTATATTTTACAATATTTGAGTGTGTTTTCAAATGTCATTTTAATCCTGTGATGCAAAACTTTGTGTTGTTACTCCAAACTTAGTGACACGTGAATGTTGATCATTTCAAGAACTATTTCTCATTGTTATTAATGTAGAAAACAGTGCTGATTAATAGCTTTGATTAAACATTTTTCAGGATGCTTTGAATCGTGTCCTGAGCAAACTTCACAAACGCTGCATCCTTAATAGTTTGACACTGCTGTGATTTGGCTTTAAATGCATAAATACTC
Associated Phenotype:
Not determined