Busch Lab

ZMP

EIF2C4

Ensembl ID:
ENSDARG00000086514
Description:
eukaryotic translation initiation factor 2C, 4 [Source:HGNC Symbol;Acc:18424]
Human Orthologue:
EIF2C4
Human Description:
eukaryotic translation initiation factor 2C, 4 [Source:HGNC Symbol;Acc:18424]
Mouse Orthologue:
Eif2c4
Mouse Description:
eukaryotic translation initiation factor 2C, 4 Gene [Source:MGI Symbol;Acc:MGI:1924100]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa29273 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa23604 Nonsense Available for shipment Available now
sa13019 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa29273
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000129463 Essential Splice Site 7 874 2 18
Genomic Location (Zv9):
Chromosome 19 (position 49546903)
Other Location(s):
Assembly Chromosome Position
GRCz11 19 47825947
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTCTGAACTTCCCCTTTGTCTTTAAACTAATATGTTGTTTCTTCTTCC[A/C]GGCCCGCCTGCCCCTACCTCCCTCTTCCAGCCACCGCGCCGGCCCGGCTT
Long Flanking Sequence:
GTGAAAAATGATCAGTTCTAAAAATAAATTGCCTAATAAATCTTCATTATTTGACTCTGTCATGAACACCACCACCAATAAAACATTGTTTAAATATTAATTCACTGTAATGCTAATGATATCAATATTGAGTGTTTGTTATCAGGATTATATCTAATGTCAGTGTATGGTTCAAGTTAAATCTCCTATTCTATACATTATTAAAGACTCACGAAACACCAAAACACATTTTTTGAGCTGTTGACAGTCGTATATGTGTCAGACACTGCTAAAAGCACTATTAGGACACATATATTTTACTAAAAAGTGAAAACCGGTAGCCATTGACTTTCATAGTATCTTTCTTTTCTCTAATATGGATGTCAATGGTTAGAGGTTTCCAACACCTTCAAAATAACTACAGTCAACTACTAAAAAAAGACACTCATGATGGTTTTTAACCAATGTAAATTTTCTGAACTTCCCCTTTGTCTTTAAACTAATATGTTGTTTCTTCTTCC[A/C]GGCCCGCCTGCCCCTACCTCCCTCTTCCAGCCACCGCGCCGGCCCGGCTTGGGTACGGTGGGGAAGCCGATTCGCCTGCTGGCCAATCACTTCCAGGTGCAGATCCCCAAGATCGACGTCTACCATTATGACATCGACATCAAACCTGAAAAACGGCCCCGCAGGGTCAACAGGTGAGAACAAGCTAATAAGCAATTCATATGAAAGGGATAGTTCAGCAATATTAAAAAAATTCTGTCCTTTTTTTTCTTTTATTAAATATTATATTATTAAATAATAAATAAATAAATTATATATATATATATATTATACATATATATTATACATATATATATATATATATATATATATATATATATATATATATATATATATACTATATAGGTATTATACATATATATTATACATATATATTATATATATATATATATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23604
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000129463 Nonsense 799 874 17 18
Genomic Location (Zv9):
Chromosome 19 (position 49524164)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 48124876
GRCz11 19 47802995
KASP Assay ID:
2261-3755.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGTGGGACGACAACTGTTTCACCGCTGACGAGCTCCAGCTTTTGACCTA[T/A]CAGCTCTGCCACACTTATGTGCGCTGCACCCGCTCCGTCTCCATCCCCGC
Long Flanking Sequence:
TTATTAAAATCCAAATTCATGCTTATGAACATTAGTTAATGCACCGTGAGTTAACATGAACTAACAATACTAGTTAATGTATTGTTCATGTTAGTAAATGCATTAAACTAATGCAACCTTATTGTAGTTAATGCGTTTACTAATATGAACAAACATTGTTAATAAAAATACAGTGGTTCATGTTAACTCAAGGTTTAACTAATGTTATCGAGCATGAATTTGTATGTTAATAATGCAATAGTAAATGTTGAATTAGCATTAATAAATGCTGTACAAGTATTGTTCATACTTGTTTATGTGTGACCAAAATATCGTTATTGCAACACTAAAATCATATTGCAATATTGTGTATTGCATATGTTCCCAGTATATAGTGGAACTTTTTTCCACACTCATTTATTTCCCCGTGTTCTCCCACAGGGCACCAGCCGTCCCTCTCACTATCACGTGTTGTGGGACGACAACTGTTTCACCGCTGACGAGCTCCAGCTTTTGACCTA[T/A]CAGCTCTGCCACACTTATGTGCGCTGCACCCGCTCCGTCTCCATCCCCGCGCCAGCTTACTATGCCCGGCTAGTGGCCTTCCGTGCACGCTATCATTTAGTGGACAAAGACCATGACAGGTTAGTAACACTTCAGTATTAAGAGCCTGTGTAAAGTGACCATAAATACGTGTTGAGCTCGTCACACAAAAGAAAATGTGGTGTTAAATGGAGCGTTCATCCTAAAATTATCATTCTAAACCTTTTGAGTTTATTTCTTCTGTTGAACACAAACGAAGGTATGTTAGAAAAACCTGTCACCATTGACTTTCATGGTAGAAGATTAAATGCTATGGAAGTCAATGGTTACAGGTTTTCAGCTTTCTTCAAAATGTCAGCTTTTGTGTTTACCAAAAACAAGAAAAGATATTTTGAAAAATGTTGAAAACCGGTAACCATTGACTTCTATAGTAGAAAATCAAATGCTATGGAAGTCAGTAGTTTGAAGTTTTCAGCATTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13019
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000129463 Nonsense 805 874 17 18
Genomic Location (Zv9):
Chromosome 19 (position 49524146)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 48124894
GRCz11 19 47802977
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCACCGCTGACGAGCTCCAGCTTTTGACCTAYCAGCTCTGCCACACTTA[T/A]GTGCGCTGCACCCGCTCCGTCTCCATCCCCGCSCCAGCTTACTAYGCCCG
Long Flanking Sequence:
ATGCTTATGAACATTAGTTAATGCACCGTGAGTTAACATGAACTAACAATACTAGTTAATGTATTGTTCATGTTAGTAAATGCATTAAACTAATGCAACCTTATTGTAGTTAATGCGTTTACTAATATGAACAAACATTGTTAATAAAAATACAGTGGTTCATGTTAACTCAAGGTTTAACTAATGTTATCGAGCATGAATTTGTATGTTAATAATGCAATAGTAAATGTTGAATTAGCATTAATAAATGCTGTACAAGTATTGTTCATACTTGTTTATGTGTGACCAAAATATCGTTATTGCAACACTAAAATCATATTGCAATATTGTGTATTGCATATGTTCCCAGTATATAGTGGAACTTTTTTCCACACTCATTTATTTCCCCGTGTTCTCCCACAGGGCACCAGCCGTCCCTCTCACTATCACGTGTTGTGGGACGACAACTGTTTCACCGCTGACGAGCTCCAGCTTTTGACCTATCAGCTCTGCCACACTTA[T/A]GTGCGCTGCACCCGCTCCGTCTCCATCCCCGCGCCAGCTTACTATGCCCGGCTAGTGGCCTTCCGTGCACGCTATCATTTAGTGGACAAAGACCATGACAGGTTAGTAACACTTCAGTATTAAGAGCCTGTGTAAAGTGACCATAAATACGTGTTGAGCTCGTCACACAAAAGAAAATGTGGTGTTAAATGGAGCGTTCATCCTAAAATTATCATTCTAAACCTTTTGAGTTTATTTCTTCTGTTGAACACAAACGAAGGTATGTTAGAAAAACCTGTCACCATTGACTTTCATGGTAGAAGATTAAATGCTATGGAAGTCAATGGTTACAGGTTTTCAGCTTTCTTCAAAATGTCAGCTTTTGTGTTTACCAAAAACAAGAAAAGATATTTTGAAAAATGTTGAAAACCGGTAACCATTGACTTCTATAGTAGAAAATCAAATGCTATGGAAGTCAGTAGTTTGAAGTTTTCAGCATTTTTCAAAATATCTACTCTTGC
Associated Phenotype:
Not determined