Busch Lab

ZMP

rock2a

Ensembl ID:
ENSDARG00000017500
ZFIN ID:
ZDB-GENE-030115-3
Description:
rho-associated protein kinase 2 [Source:RefSeq peptide;Acc:NP_777288]
Human Orthologues:
ROCK1, ROCK2
Human Descriptions:
Rho-associated, coiled-coil containing protein kinase 1 [Source:HGNC Symbol;Acc:10251]
Rho-associated, coiled-coil containing protein kinase 2 [Source:HGNC Symbol;Acc:10252]
Mouse Orthologues:
Rock1, Rock2
Mouse Descriptions:
Rho-associated coiled-coil containing protein kinase 1 Gene [Source:MGI Symbol;Acc:MGI:107927]
Rho-associated coiled-coil containing protein kinase 2 Gene [Source:MGI Symbol;Acc:MGI:107926]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa12939 Nonsense Available for shipment Available now
sa42240 Nonsense Mutation detected in F1 DNA Not yet available
sa44793 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa12939
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081971 Nonsense 139 1357 5 31
ENSDART00000133882 Nonsense 157 1375 5 31
Genomic Location (Zv9):
Chromosome 13 (position 33073170)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 32719118
GRCz11 13 32849568
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGTGCTGTGCGTTCCAGGATGACCGCTCTCTCTACATGGWAATGGAGTA[C/A]ATGCCAGGTGGAGATCTAGTCAATCTCACCAGCACATATGATGTCCCAGA
Long Flanking Sequence:
TCCAGAGGAAATGTGGATGCATGCTTTGTGAGCCTTCCTGACTGAATGAATCAAATTCGCTGTTTTACACCAAGGCAACTCAGGGTGCTTAAAATAATTGGCATTGGGTGGGTTAAAAGCACCAAAACAAAGACAGTACCAGCATGTAACAGACATTTTCAAAGCAGAATAACTGACTTTAGCATAGTCAGTTTTTAGCATTTTCAGATAAACAAGTATGTTCACTTAGCATGTTTCATAAATATCTGCAAACATACTATGGTATTTTTATGCTTTAGAAGAGTCAAAAACTTACATACAGCACCTATAATGGGGCTATATTTATTGGTCTAGAATTATTATATCAGTATATCCCTATGCACACTCTGTCAGAATTTGAGGGTAATAAAAACAACTCCTAATATTTTCTCATTTTTTCCCCTCTTTTGTTTTTTCTTCTTTTTCCCTTAGCTGTGCTGTGCGTTCCAGGATGACCGCTCTCTCTACATGGTAATGGAGTA[C/A]ATGCCAGGTGGAGATCTAGTCAATCTCACCAGCACATATGATGTCCCAGAGAAGTGGGCAAAGTTTTACACAGCAGAGGTGGTGTTGGCTTTAGACGCTATTCACTCCATGGGCTTCATTCATCGAGACGTCAAACCAGACAACATGCTGCTGGACCGCTACGGACACCTCAAACTGGCAGACTTCGGGACCTGCATGAAAATGGATGGGGTGAGGGATCAACTGCTTTTTGCACAACCAAGGTTTCAGTAATTCTCAGGCTTGAGCTTTTTGAGTACAGGGATTTTTAGGTCACCCCTGAATGTAATTGCAAGTCAAATACCTTGAACGCATGCCAGTTCTTGTCCAGACTCATGAGAGCAAAGGAAAAAAATGTCAGCCTTCCTCTGATTTCTCTATGTGAGTGAGGAAGACCTCAGGTGGGTTCAGAGGTCAGAGGGTCAAACTGAGACTAAGAAGCGTTTGTGTTTTAAAAATCCTCAGCTCATGTTGACTGATGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42240
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081971 Nonsense 531 1357 13 31
ENSDART00000133882 Nonsense 549 1375 13 31
Genomic Location (Zv9):
Chromosome 13 (position 33064831)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 32710779
GRCz11 13 32841229
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAACCAGAACTCGCACATCTCCAACGAGAAGAACATCCACCTGCAGAAA[C/T]AGGTTTGTACGTCTTTTCAGCCCATGACCCACTAAAATGAAGCACACACA
Long Flanking Sequence:
GCCTAAAATTCAGCTTAAGTAATTTATGGTTTGCAAATTCAGTAAAGATTGCCTCATTTTTCACTCAGCTCCAGAAGAAGCTTCACTGTCTAGAAGAGCAGCTCAACAATGAAATGCAGGCCAAAGATGAGTTGGAGCAGAAATACAGAAGCAACAGTAACCGCCTGGAAAAGATCACCAAAGAGCTCGATGAAGAGGTGAGTGCGTGTTTCATCTCTGAGACCTCTGTGAAGTTGCATGTGGGAATACTTTAAGCTTGCTCTTGCGTGTTGTAGATGAATAGCAGGAAAGGTCTGGAGTCGACCCTGAGACAGCTGGAGAGAGAGAAGGCTCTGCTGCAGCACAAGAGTGTGGAGAGTCACCGCAGGGCCGAGAGCGAGGCCGACCGCAAACGCTGCCTGGAGAATGAAGTCAATAGTCTGAGGGATCAGCTGGATGAAATGAAGAAGAAGAACCAGAACTCGCACATCTCCAACGAGAAGAACATCCACCTGCAGAAA[C/T]AGGTTTGTACGTCTTTTCAGCCCATGACCCACTAAAATGAAGCACACACACCAATAGGCCAATATAAACATGAGCATTTTGATAAGACAAAATTAAAAAGATCCAACTGTCTAGCAACTATGTAATTTAGTCATTTATTCATTTGTTTAATTTTAACATTAACCTCACCTTATTAGATTGCTGGGCACAATGTTTGGAGCACAATGAGTCCATTCTGGGTTTAAGATTCCTCCATGTTCAGTCATAACCGGCATTTATTTTTAATGTGAGTTCAGAAAAGGGTAAAGTTTAATATAATCTGGAGTGGGATGCATTAGAGAGTAATAAATTGTATGAAATACAACCTGAAATCTCAAACAGACTAGATTTGATCAAACGATTTTTAGCAGATGACGTATTGGACATACAAGAATAACTCATGGCTTTTTGCTGAAAGGGTCACGAAACACTAAAACACGTTTATTGAAATGTTGACAGTCATATGTGTCTCACATTGCTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44793
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081971 Nonsense 862 1357 20 31
ENSDART00000133882 Nonsense 880 1375 20 31
Genomic Location (Zv9):
Chromosome 13 (position 33056081)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 32702029
GRCz11 13 32832479
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACACAAGTGCGAGAGCTGAAGGAGGAGTGTGAGGAGAAAAATAAACTTTA[T/G]AAAGACGTGCAGCAGAATCTACAGGAGCTGCAGGAGGAAAGGTGAGATTT
Long Flanking Sequence:
AGTGTGATACATGTAAGGTTAGGGACAGGTCTCGCGGTATGGGTAGGTTTAAAATTCTGTTAAGGTAACGAATGGGTCAACCGTGTAATTCTGAATGTAATTAAATGATTTAATTAAAAATATTTTAGCAAGCATAGCATTTGGATGTAAACAATAATCTAGTTAAGATGAAAGAAACAGTAGATATCCACATTGATGAGCAATTGTGTAAAGGAGACAAATATATGTCTGCAACTCTCCTTTAAAAGCATTTTAAGAGAAAAAGCACACACTGGATGAGAATGAATCTGTCTAGTGCACAAGTATTGAGCGCTGCTGTTCATGCATGCTAGCAGATAATTGTAAAATGTTGTGTGCTGAGGTGTTTGTGTAACTAGTGCAAAAACAAATACCCTGTGTGTGTGGACTTTACAATTCTTTTTGTATGTATGTGTGTAGACGCTGTATAAGACACAAGTGCGAGAGCTGAAGGAGGAGTGTGAGGAGAAAAATAAACTTTA[T/G]AAAGACGTGCAGCAGAATCTACAGGAGCTGCAGGAGGAAAGGTGAGATTTAATTCCAATAAAAATACTATGCAAATTGCAATTTTACTGGATTATTCAAACTTTTGTATCTAATTTGTTGAATTTGGATCAAAATTAAACCTTTAAATCGTTTTAATTTTTTATCTTAGGTTTTATTAATTGCTGTTTATGTCTTTTAATTGTTTTAGTTTTATTATAATATCAATAAAGTGATATTTATAAAATATTTGATCTGATTTGCCATGAAAAAGGCAAATAGGCTGACATGGCCATACATTTAAAAATCTATTGCATCTAATTTGCAGCTAAATTAATTTTAATTAATTTTTTTTTCTTTTTTAATTTAACAATGTTGGTTTAATACCTATGTGCCGTTTATGTCTCTGTTTCTCAGGGATTCACTTGCGGCCCAGTTGGAGATCACACTAACCAAAGCAGACTCTGAGCAGCTGGCACGCTCTATTGCGGAGGAGCAGTATT
Associated Phenotype:
Not determined