Busch Lab

ZMP

crb2

Ensembl ID:
ENSDARG00000060106
ZFIN ID:
ZDB-GENE-060612-1
Description:
crumbs homolog 2 [Source:RefSeq peptide;Acc:NP_001038764]
Human Orthologue:
CRB2
Human Description:
crumbs homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:18688]
Mouse Orthologue:
Crb2
Mouse Description:
crumbs homolog 2 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:2679260]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa12901 Nonsense Available for shipment Available now
sa32334 Essential Splice Site Available for shipment Available now
sa18328 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa12901
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084378 Nonsense 403 1466 5 13
Genomic Location (Zv9):
Chromosome 21 (position 7984580)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 8392131
GRCz11 21 8484670
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAACACTGGGAAACAGACTGGGAGTTCACTTATGCCACAGCTGTGGGCTA[T/A]GTATGTCAGTGCCAACCAGGATWCACAGGTACTGGYAACGTCACTACACR
Long Flanking Sequence:
CGACAGAGTCATGCACAATAGCATGCCTATACACTGCCCATAGTGTTTTCATTTACTGTCTGTAAAATAAATTTAACATGTTAGTCAACATTCTAAGTTTATATTGATAGTTACAATACACTGACTTTTTTATTTGTATACAGTTATGAGTGTGAATGTGAAGGCACTGGATATATGGGAGACCACTGTGAAGAGGATATTCCAGAATGTGCATCACATCCTTGCCAACATGGAGGAACTTGTCTGGAGGGCATTAACCACTACAACTGTTCCTGTTGGCCAGGTAAGTCTCATTTATCTAATCATGGTACTCAAGCCTTTGTAACTTTGATATAATCTAAAATATTTGTGTGCATAGGTTTTGAAGGTGGTAACTGTGAGGTGGATATAGATGAATGTGCTGATGCTCCATGTGAGAACGATGGTGAATGTTTTGAAAAGTCAAATCCGGAACACTGGGAAACAGACTGGGAGTTCACTTATGCCACAGCTGTGGGCTA[T/A]GTATGTCAGTGCCAACCAGGATACACAGGTACTGGCAACGTCACTACACATATGTAGTGAACATTTATATGTAACTGAATAGATAGTCTAGTTAACTTGCAATGTTTTACTTTCAAAATAATTTAGTCATGCTGTAGTTCATCTGAATGTTTGACATTTCTTTATAGGAGAGAATTGTTCAGTGAACATAAATGAATGTGTGTCCGAGCCATGTCACAATGGTGGAAGCTGTAAGGATTTGGTTAACGGATACATGTGTGAATGCCCAGAGGGATTCACAGGTTAGTTTTTACAAATAAGAAAGCTTTTACATTTGTATCTGTTCATATTGCTAACTTGGGTCTGTCTTACTCAGGTGTGGAATGTGAGGTGAATATAGATGAGTGTGAGAGTGCCCCCTGCCTTAATGGAGGTGTATGCGAAGATGGAGTGGCTGAATACAAGTGTCACTGTGCAGAAGCTGAGGAAGGTCTGTTGCCATGGGGCGGACCCCAGTGCAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32334
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084378 Essential Splice Site 1021 1466 9 13
Genomic Location (Zv9):
Chromosome 21 (position 7982155)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 8389706
GRCz11 21 8482245
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCATGCATAAATGGTGGACACTGCGTAGATCTGTTGGATGGTTTTGAAT[G/A]TACGAAGCAGATTTTTGACAATTTCTTGATTGCTTGCTAAAGACTAATAG
Long Flanking Sequence:
ACGGGCTTGGCTTACTGCCCGACTTGGAAGTTCTGGAGGGAGACTTGTTGTATATTGGTGGAGTTCCAGGTGAAGAGGGTGCAACTGTTTGGGGTGGTCATTTTAAGGGCTGTCTGCAAGACCTGAGACTGGACGACGTGCATCTGGATGTGGAAGACTGGAATAATACACTCAGTGAGAGCATCTATATCGCCAGTGATTCAGAAAATGTCCTTCCTGGGTGCACGAGTGATGACACTTGCAAGGTACATAGATTACATGTAGGTTTTGTTTCACTAAATGTGTTCCTGCTGATGCAGTTTCGAAAAGCTAATGTCATGTGGTTGGTTTGCAGATGGAGCCTTGCTTAAATGGAGGAGCATGCACAGTCACATGGAATGACTTTATTTGTTCCTGTCCAAAGGATTTCACAGGAAAGACATGTGAAACCAGAGTTTGGTGTGTCAGCGATCCATGCATAAATGGTGGACACTGCGTAGATCTGTTGGATGGTTTTGAAT[G/A]TACGAAGCAGATTTTTGACAATTTCTTGATTGCTTGCTAAAGACTAATAGTAAATTTAAGTCTATAAAAGTGGATATAAGTTGTAACAAAATGTTTTGTTATGTCTTACCAGGTATAGCGAACGCAACCTTTGACAATACCCCTTTACACTACAGTGCTAAGGGATCTCTACTTGACCCAGTGACCAATGTTACCATGAAGCTCCGTACAAGACAGGAAAATGGTGTACTACTTCGTGCATGGCGTGGGGAGGAGCTTCTACTGATTGGTCTGTTGGATTCATCCATTCATGTGGAGATTCACACAGCGAACAGTGTAGAACCAGTGAAGTTCTCTGGACAGAGACGCATAGCAGATGGAAACTGGCATCGACTGCTGTTTGCGATGGCCCACCCAGAGCATGATGCGTCACAGTGGTTCGTTTTGGTGGATGGCATCATCGATGGTAGCAGTGCCCCAGTGCTTGCAGGTAGTTTAAATTTTCTTAAAGACATATCAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18328
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084378 Nonsense 1108 1466 10 13
Genomic Location (Zv9):
Chromosome 21 (position 7981785)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 8389336
GRCz11 21 8481875
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACCAGTGAAGTTCTCTGGACAGAGACKCATAGCAGATGGAAACTGGCAT[C/T]GACTGCTGTTTGCGATGGCCCACCCAGAGCAKGATGCRTCACAGTGGTTC
Long Flanking Sequence:
ACATGGAATGACTTTATTTGTTCCTGTCCAAAGGATTTCACAGGAAAGACATGTGAAACCAGAGTTTGGTGTGTCAGCGATCCATGCATAAATGGTGGACACTGCGTAGATCTGTTGGATGGTTTTGAATGTACGAAGCAGATTTTTGACAATTTCTTGATTGCTTGCTAAAGACTAATAGTAAATTTAAGTCTATAAAAGTGGATATAAGTTGTAACAAAATGTTTTGTTATGTCTTACCAGGTATAGCGAACGCAACCTTTGACAATACCCCTTTACACTACAGTGCTAAGGGATCTCTACTTGACCCAGTGACCAATGTTACCATGAAGCTCCGTACAAGACAGGAAAATGGTGTACTACTTCGTGCATGGCGTGGGGAGGAGCTTCTACTGATTGGTCTGTTGGATTCATCCATTCATGTGGAGATTCACACAGCGAACAGTGTAGAACCAGTGAAGTTCTCTGGACAGAGACGCATAGCAGATGGAAACTGGCAT[C/T]GACTGCTGTTTGCGATGGCCCACCCAGAGCATGATGCGTCACAGTGGTTCGTTTTGGTGGATGGCATCATCGATGGTAGCAGTGCCCCAGTGCTTGCAGGTAGTTTAAATTTTCTTAAAGACATATCAAGCGAGGTTGCACTGGCCGAGACCTTCACAGGATGTCTAGGTGCTGTCAGAGTGGGTGGAGTTTACCTTCCATTTGTGGACAATACCAAATCACCCCAAACAACACGGTTTTGGCGAAGACCAGATGAGCATGTACACTTGGGATGCTTTGGGGCACCAGTCTGCCGCTCTCATCCCTGTAGGCGTGGTGGCACATGTGTGGATCTCTTCAATAAATTTGGTTGTAAGTGCCCATCTGGCTGGGAAGGGAACATTTGTGAGAAGGAAATAGACGAGTGTATCTCGGGACCTTGCCTTCATGGCAAGTGCAAGGACAAGCTTAATGGGTTTGACTGCTTATGTCACCCAGGATACGCAGGACCTACATGTTCA
Associated Phenotype:
Not determined