Busch Lab

ZMP

APC2

Ensembl ID:
ENSDARG00000063007
Description:
adenomatosis polyposis coli 2 [Source:HGNC Symbol;Acc:24036]
Human Orthologue:
APC2
Human Description:
adenomatosis polyposis coli 2 [Source:HGNC Symbol;Acc:24036]
Mouse Orthologue:
Apc2
Mouse Description:
adenomatosis polyposis coli 2 Gene [Source:MGI Symbol;Acc:MGI:1346052]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa31814 Essential Splice Site Available for shipment Available now
sa41778 Nonsense Mutation detected in F1 DNA Not yet available
sa12808 Nonsense Available for shipment Available now
sa4406 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa31814
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091664 Essential Splice Site 241 2105 5 14
Genomic Location (Zv9):
Chromosome 11 (position 7442436)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 7286539
GRCz11 11 7296378
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGATGGAGGAACGTTTCGGCACCAGTGATGAGATGGTCCAGAGAACACAA[G/A]TAAGAACAGATTATAGATTTAATGCCACGTTTCACCGACAAAGATGCAGC
Long Flanking Sequence:
ACATAAACATATCAGACAAATAATAGTCTTTTGAACTTGAATGCTCATTACTGAATTCCCCTAAACCTTGTTGAGTACAGTGAATTTAAGTTTCAGTGTGTGTGTGTGTGTGTGTGTTTTGTAGGACTATGTTGCTGAGTGAAATAGAGAAAGAGGAGAAAGAGCGACGGTGGTATTACTCACAGCTGCAGGGATTGTCTCAGAGACTGGCTGAACTGCCACGGCTTGATACGGTAAGCCTAAACAACTTCCAGTTACTCACTTCTGAGTCTCTTGATTTTACTGGTAATGACTATAGATTTGGCTTGTTTTGATTGTGGAAACAAAGTTATGTGTGCAGTTTTGTTAATTGTATGATTATTAAAGATACGTTTCTTGCCTCACAGTTCTCTATGCAGGTGGATTTTATCAGACAGCAGCTGGAGTTTGAAGCTCAGCAGCTGCGTTCTGTGATGGAGGAACGTTTCGGCACCAGTGATGAGATGGTCCAGAGAACACAA[G/A]TAAGAACAGATTATAGATTTAATGCCACGTTTCACCGACAAAGATGCAGCTGTAAATCCAGCTTAAATGTCACGTGTCAGTCACAAGCCATACTTGTGTAAACCACAGAACTCGCAGTCAAGCATCCAGCACAATGTTGTTTTGGTTACAACTTGTTGTTTTAACTACCCAAAACAACCCACTTCATCATAAACACCGCACTGGATGAACCACAAGGCTAAACTAACTGAGATTATAGGGGTTTATCAATGATGTGCTCTTAAATTATTATTATCAAAAAGCCCGTTATGTGTTACCGCATACAGATCCGTGTTGCTCGGTTGGAACAGCTAGAGAAAGAGCTTCATGATGCCCAGAGCTCACGTGGTCCTCAAGAGAAGAGCGCTCTACCTGAAACACAGGTAACACATACACACACTTCTTTAAAATGATTAACAATGTGTCCATGATGTTTAGGCTAAAAATTAGGCGCAAGTTCAGTCATGAGAGTTCAGAGTTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41778
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091664 Nonsense 1068 2105 14 14
Genomic Location (Zv9):
Chromosome 11 (position 7430412)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 7274515
GRCz11 11 7284354
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACTGTTTCAACAAAGGTTTCTTCAGAAACTAGCATACCAACTGTCAAGT[T/A]GTCTCCCTCCTATCAGCATGTTCCACTGATCCAGAGTGTTGCCAAGTTTG
Long Flanking Sequence:
TTCAGAAGATCATTTTTTGGATTGGAATTACGGGCCAGATGAGCTTCATGAAGCGAGAGCCATTTCATGCTCCCCATGTCCTCTCTCAGATAGCAGCACTTTTTCTCCTAAAGAGCGTCTCAGCAGAGCACATGCCTTTATGCGTCTTAAAACAACAAACTCAAGCTTATCCAATGACAGCCTTAACAGTGGTAGCATCAGTGATGGCTATTGTGGCAGTCAAGACCAGACTCATCCCTCTGCCAGACCAACAGAACAACGACGTCCAAATAAGCTTGACCTTAAGGTAGCTCATGAGGAACCACTGACTAGTGGTGTACATATTTCAAGAGTCTTGTGTCAAAATGAAATACCTGAAAGAGATTTCGAGGCAAACAAAGATGCTATTTTGCCTGATTCAGGATCCACAGATACAGAGAAAAGCCAAGAGCCATTTATATCAACCCCTGCAACTGTTTCAACAAAGGTTTCTTCAGAAACTAGCATACCAACTGTCAAGT[T/A]GTCTCCCTCCTATCAGCATGTTCCACTGATCCAGAGTGTTGCCAAGTTTGGTGTTGCAAAGACTGCAATTAATGTTCAGGCAGCTCAAGCAATGCGCAGGCAAGCTTGGGTTCCAGCAGTTATGACTGGTGGAAGCATTAGCAAGTTTTCCCCAATATGTTCTGCAAGAAGTCCCACAATAGGACAGCTGGAAACTCCTCAGAAGTATTCTGTAGAGAACACTCCAATATGCTTCTCTCGTTGCAGTTCTCTGTCCTCTTTGTCCTCTGGGGATGGAGCTCTTGATGGACAAAGTCAAACTGAAAATGAGCTAGAAAGTGACTCCTCATTGGAAATCATAGAGGTAGAAGACGTGAATGTTGAGAGAAAAGATGAAGAGGATGAGAACGAGACACTTGATGACTTGAGTGACAGTCAGTTATTAGTAACTGATCAGAAAATCAGTAGCTCTGACCCAATTGAGATCTCTGGTACAATCAAAAATGAGAAGAGGTTCCTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12808
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091664 Nonsense 1722 2105 14 14
Genomic Location (Zv9):
Chromosome 11 (position 7428451)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 7272554
GRCz11 11 7282393
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACATACAAGATCAAGTCAACAGTTATCAGTCCCGCCAAAATGGTTTTCAC[A/T]GRATCAAACAAAATCTAATTTTAGAAGAAGCACCTCCATGCTACTCTTTG
Long Flanking Sequence:
TTGAAGACCTACGCATGTTCTCTCGCTTCCACAAACCAACTAAAATAGCATGTCAGTCTCACCTAGTCACGAATCAACTGAACAAAACGATCAGAAGAATGGTTCCCACTCAGAGATTACTAATACAAAGTAAAGAGATGGCAGCAAAAATGACCCAGCAACGAATTCAAAGCCAGTCTCCAGTTAGACAAATTCAAAAGCAAGGACAGAATCTGTCAAGAAGCATGCCACAGTTGGATTTTCCCATGAGAAAACAAAGCACTGAGGTGTACCAAAATCAGAAAACCTGCTATCTAAGTCATGTGCAGGAAAACACTCTATCCCTAAAGTCGAGGCGTCATCCATCATCTACAGAAGGCATTTGTCATAAAATGGAAAGGCATGATGGACAGATGAATAGGACTGGACGGAAACAACAATATGATTCAAGCAATATAATACGTAATGCTAACATACAAGATCAAGTCAACAGTTATCAGTCCCGCCAAAATGGTTTTCAC[A/T]GAATCAAACAAAATCTAATTTTAGAAGAAGCACCTCCATGCTACTCTTTGAGTTCCTCTCTTAGTTCTTTAAGTGATGCTGAATTTGAGGAACATGAAAATCCTCAACATACGTGGATAAAGAATAGACATAACATAATGTCCAACCTTCAGTGCCATCCAAAGTCACAGAAAGACCTCAACCAGTTTGAAGAGAACAGCTCGCCTAGTTCAGTCAGCATGGATTCAGAAGATGATCTTTTGATAAAATGCATAACATCTGCTATGCCACAACACAAGAAAAGGCAAGCTGCCCGAAAACGAAAAGCTGAGAAAAAGCACAAACAAAAAGCTACTCTTCAGAAAGCAGCAGAGGACAGGGGTCTTGATAATGACCTAGATAGTGATGAAATGGCATCAGACAAGGACTCTGATCTCAATAGTGTTGAATGGAGAGCAATACAAGAAGGAGCGAATACAATCATAACCAAGTTACAAGCTTCAAAGTCCCAGGAACCCTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa4406
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091664 Nonsense 1830 2105 14 14
Genomic Location (Zv9):
Chromosome 11 (position 7428127)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 7272230
GRCz11 11 7282069
KASP Assay ID:
554-3589.1 (used for ordering genotyping assays)
KASP Sequence:
ACAAGAAAAGGCAAGCTGCCCGAAAACGAAAAGCTGAGAAAAAGCACAAA[C/T]AAAAAGCTACTCTTCNNNNNNNNNNNNNNNNNNNNNNNNTTGATAATGAC
Long Flanking Sequence:
TAAAGTCGAGGCGTCATCCATCATCTACAGAAGGCATTTGTCATAAAATGGAAAGGCATGATGGACAGATGAATAGGACTGGACGGAAACAACAATATGATTCAAGCAATATAATACGTAATGCTAACATACAAGATCAAGTCAACAGTTATCAGTCCCGCCAAAATGGTTTTCACAGAATCAAACAAAATCTAATTTTAGAAGAAGCACCTCCATGCTACTCTTTGAGTTCCTCTCTTAGTTCTTTAAGTGATGCTGAATTTGAGGAACATGAAAATCCTCAACATACGTGGATAAAGAATAGACATAACATAATGTCCAACCTTCAGTGCCATCCAAAGTCACAGAAAGACCTCAACCAGTTTGAAGAGAACAGCTCGCCTAGTTCAGTCAGCATGGATTCAGAAGATGATCTTTTGATAAAATGCATAACATCTGCTATGCCACAACACAAGAAAAGGCAAGCTGCCCGAAAACGAAAAGCTGAGAAAAAGCACAAA[C/T]AAAAAGCTACTCTTCAGAAAGCAGCAGAGGACAGGGGTCTTGATAATGACCTAGATAGTGATGAAATGGCATCAGACAAGGACTCTGATCTCAATAGTGTTGAATGGAGAGCAATACAAGAAGGAGCGAATACAATCATAACCAAGTTACAAGCTTCAAAGTCCCAGGAACCCTCATCAGAGTCTGAGTCAGTTTTGTCATTTATGTCTGGCTCAAGCTTTACTCCTAAAGAGAAGAAAGTATACAAAGATGACAAAAAGGCTAATAAACCGCTTGATTTTGCCCCTCGTAAACCTGTACCAAACTTCCCTGTGGTCTTCAGGGGTAGAACAGTGATATACACACCCAAAAAGGAGACAACACTCTCTCAGAGACCACCACCTAAAAAGGTGTCACCGAAAGCAGATGCCCCTAAAAATCCAAATCTAGCTCAACATAGGTCAAGAAGCCTTCACAGACTGGGCCAACCCATGGAGTCCACTCAATTGTCTTTGCCCAAA
Associated Phenotype:
Not determined