ZMP
polr2b
Ensembl ID:
ZFIN ID:
Description:
DNA-directed RNA polymerase II subunit RPB2 [Source:RefSeq peptide;Acc:NP_001019632]
Human Orthologue:
POLR2B
Human Description:
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa [Source:HGNC Symbol;Acc:9188]
Mouse Orthologue:
Polr2b
Mouse Description:
polymerase (RNA) II (DNA directed) polypeptide B Gene [Source:MGI Symbol;Acc:MGI:2388280]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa12802 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa12802
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000041408 | Nonsense | 290 | 562 | 7 | 12 |
| ENSDART00000124865 | Nonsense | 290 | 1117 | 7 | 25 |
| ENSDART00000128452 | Nonsense | 290 | 366 | 7 | 8 |
The following transcripts of ENSDARG00000012592 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 14 (position 53579122)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 14 | 51684633 |
| GRCz11 | 14 | 52400327 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGCGCTTTAGGAWTYGTGTCTGACAGAGACATTCTGGAGCACATCATCTA[T/A]GACTTCGATGATCCGGAGAKGATGGAAATGGTATGTCACATGAGCGCTGT
Long Flanking Sequence:
AGTGGGCGGAGTTACAGATCAAAACAAAGACAGACATTCCCAGACAGAACGCACATTTTCAGAGCAGGATACCTGATTTAGCATGGTTTTACAGATAAATATGGTCACTTAGCATGATTCTGAAATATCTGCAAACATATTATTGAATTTTAATGATTTACAGGAGTAAACTATGTACATTCAGGAGCTTTAACCCTTTTCACACAATTCCAAAACCACTTTGAACAAGTGTAAAAATGTTTTTTATGAATAAGAGATTTTTGTTTAAAATTTGGCATCATTTAATACTTCAATATGTGCATTAGCACAGGGTAATGGAAACCAAGCTAGTGTTGAATTTTCTGCAATTATTTCTGTATATTTCAGGGAGTAAAGAAAAGTGCCATCGGTCAGAGGATCGTCTCCACGCTGCCGTATATCCGGCAGGAGGTGCCCATCATCATCGTGTTTCGCGCTTTAGGATTCGTGTCTGACAGAGACATTCTGGAGCACATCATCTA[T/A]GACTTCGATGATCCGGAGATGATGGAAATGGTATGTCACATGAGCGCTGTGCAGTAATATACAGTTTAGTTTAGAGCGTAATTAATCCCCTTGGTTTATTCATTCTGACAGGGTATGGTGCATCACATATAACACAAAGGACAGACTGAAATACCAACACTTACCTTCAATCGTACTCCACTGTCTGTCCACAGGTAAAGCCGTCTCTGGATGAGGCGTTTGTGATTCAGGAGCAGAACGTGGCTCTGAACTTCATCGGCTCCAGAGGGGCCAAACCTGGAGTCACTAAAGAGAGGAGAATTAAATACGCTAAAGAGGTTCTGCAGAAGGAGGTGCTGCCGCATGTGGGTGTGTCAGACTTCTGCGAGACCAAGAAGGCTTACTTTCTAGGGTAAAACGGTGTTTATTTAGTTGCATTTATTTAAGTCTAAACAAACATATTTCAGTGGCCTTTTTTATATTTGTAAAACATTTGTTCAAGAAGTAAACTCACTTAAAGA
Associated Phenotype:
Not determined