ZMP
lmnb2
Ensembl ID:
ZFIN ID:
Description:
lamin-B2 [Source:RefSeq peptide;Acc:NP_571077]
Human Orthologue:
LMNB2
Human Description:
lamin B2 [Source:HGNC Symbol;Acc:6638]
Mouse Orthologue:
Lmnb2
Mouse Description:
lamin B2 Gene [Source:MGI Symbol;Acc:MGI:96796]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa8882 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa24050 | Essential Splice Site | Available for shipment | Available now |
| sa3163 | Nonsense | Available for shipment | Available now |
| sa12800 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa8882
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000009438 | Essential Splice Site | 68 | 583 | 1 | 12 |
Genomic Location (Zv9):
Chromosome 22 (position 1220080)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 22 | 3134673 |
| GRCz11 | 22 | 3151946 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACCGGCTGCAGTTTAAAGTGTCCGAGAAGGAGGAAGTCACGACCAGAGAG[G/A]TGCGTTCCGCTCCTTTGTGTGCGTTTTTATTGATCCATAAATCMACGAAC
Long Flanking Sequence:
GTTTAACAGCATTTTGGACTACAACCCCCAGTGAGCACTTCGGGCGACTTTTGGCGCGGTTTTACGTTAGCGTCGGCCATTTTCTTTTCACACCTCCGTTTCAAAGGCAGCCAACCAGCAGTCGGACTACAAACACACGCTTTCATTGAGAAAACTCCACAAAACCACGCAAACTTCCTAACGCGCCGCCGGAAAGCCGCTGCAAGTGCGACTCGGAGGCCGCTGCTCAGTGGGACGCGAAGGAGCGTGTGTATTTTTCTCTGAGGTGAAGAAGAGGGTCTGAAGCGATCATAATTATGGCGACCGCAACCCCGAGCCGCGCGTCGGCCGCCCAGACGCCGCTGAGCCCCGCGCGGATCTCCCGCCTGCAAGAGAAAGAGGAGCTGCGGGCGCTCAACGACCGCCTGGCCGTGTACATCGACCGCGTGCGCGCGCTGGAGCTCGAGAACGACCGGCTGCAGTTTAAAGTGTCCGAGAAGGAGGAAGTCACGACCAGAGAG[G/A]TGCGTTCCGCTCCTTTGTGTGCGTTTTTATTGATCCATAAATCCACGAACGCCGCCCGCCTTTTGCTTTACAAACTCGGTTTTGGGTTAAATCCACCACTTTGAGAAGGGAATCGCGTTTTAAGCTAAACTATGTTGGTCATTGTAACGTTAATTAAGTCTAAAGGTTGAATTATTGAATAAAAAGTGTTCACTTTTGTGAATGTTACTCCTTTAGCCTTTTATAAACTCGTTTATGCATCAAATCCTCGTTGTTACGCGGGGAATCGCGTTTTAAGGTAAACTATGCTAGTCAATGTAGCATTATTTAATGTTTATGAAACATTGAGGAGGGGGGGGGGGGGGGGTTGTTTGCTTTTTCTTGTGGTCACCCGTCTTGCTTTTATAAACTCGTATTTACCTAAAATCTGCGCCTTAAAACGGGGGATTAAAAACAAATTTCTATGTAAACTAAATTGGTGAATTGAAAGTGTTTCGATGTTTTTAAAACAAACGTTTTGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa24050
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000009438 | Essential Splice Site | 381 | 583 | 7 | 12 |
Genomic Location (Zv9):
Chromosome 22 (position 1202318)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 22 | 3116911 |
| GRCz11 | 22 | 3134184 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACATGGAGATCAACGCCTACAGGAAACTGCTGGAGGGAGAGGAGGACAG[G/A]TGAGCCTCAACACCACACTAAACACCTGCGCTCTTCACAAGACATCAACA
Long Flanking Sequence:
CATCAACTGACATGTTAATATACATGTCTATTATTATCTAGAAATCTGACTGTTACATTTTATAATACTTTAATAAGATATTCAGTGAACTTTTATCTCAAATTGTTTTAGCTAAATATAGGTTTCTCTAATATATCTTGTTTGAAAAAAGAAAAGAAAAAAAAGAAAAACAGGATTTGAGTTTCTAGGAATTAAATTCCACTCATTCCATCGTGGTTAATGCTGTGGTGAATAACGAGACATCATTCCTGACATGTTTTCCTCTTCCTCCACCTGCAGGCGTCCGCCGCTGAGGAGCGCATCCGCGAGCTGGAGGGCCTGCTGTCCAGTGACCGGGACAAATACCGCCGCCAGCTGGACGCTAAAGAGCGCGAGATGGCAGAGATGAGGGAGTGCATGCAGCAGCAGCTCAACGAGTACCAGGAGCTGCTGGACGTCAAACTGGCCCTGGACATGGAGATCAACGCCTACAGGAAACTGCTGGAGGGAGAGGAGGACAG[G/A]TGAGCCTCAACACCACACTAAACACCTGCGCTCTTCACAAGACATCAACATGTGTTCTAAATGAGGGATTTAGAATGTGCGGAATCTAAAATGGAACACTGGATTCCAAATCAGACATTGTTCTGCGAAGTAATTTGCATACTTCAATTCGAGTTCATTTGTGTTGCTCTTTTCACAATATTAGAGGCCTTAAGACGAAGAACCATGTAAGTCCATATTTTTAAATTTGGAGTTTAATTTTGTAGTTTAATTTTGAATTTAATATGATTTTTTTTTTCATTTGGATTGTGAACATTATTTTATATATAATTTTATCTTACTTGAATATAGACAACAAAAGCTTCTCAATTCTGAGATCACATTTTCTTGTGTCAGTATTAAAAATCAAAAGTTATTGTGATTTTGTATCTCTCAAATGTGAAAGAACAGTCCAGGAAGTGTAGAACAGGTGTCACCAACCTTTTAGGGTACTGATTAATGTGAAGGGCTACCAGTTTGAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa3163
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000009438 | Nonsense | 429 | 583 | 8 | 12 |
Genomic Location (Zv9):
Chromosome 22 (position 1196055)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 22 | 3110648 |
| GRCz11 | 22 | 3127921 |
KASP Assay ID:
554-2718.1 (used for ordering genotyping assays)
KASP Sequence:
AGAGGAAGCGTGTGGAGCTGGAGGAGTCATCCACCGCCGGCCCCAAAGTG[C/T]AGATCAGTCAGCAGGCTGAAGCCAGCGGCAGSGTCAGCATTGAGGAGATC
Long Flanking Sequence:
AAAACTATTATGTTTTGAAATGTGCTGAAGAAATCTGCTCTCCGTTAAACAGAAATTAGGGAAAAAATAAACAGGGTGACCAATAATTCAGGAGGACTAATAATTCTGACTTCAACTGTATATGCTGTAAAAATAAAAAAAGCACTTTTACTGGAAGTTTTGTATGTACTTTCTACAAAATCTGCTCTGTTAAAACTGCAATTATGATATGATTGCAGACAATATTTAAATGTACACATCACACAAACCCCTAGCACTCATAAAAGCACCACATGTTCATTCTTCAGACACACACATGCATGTACATCTCCTGCGGGGTTCGAGTGCAGATCTATATGTTTGTTTGATTCTCTTCCAGGCTCAAGCTGTCTCCCAGTCCGTCCTCAAGGGTGACGGTGTCCCGCACCACAGCGAGCAGCACCTCTGCGTCCTCACGGAGCTCTCGTGCCAAGAGGAAGCGTGTGGAGCTGGAGGAGTCATCCACCGCCGGCCCCAAAGTG[C/T]AGATCAGTCAGCAGGCTGAAGCCAGCGGCAGCGTCAGCATTGAGGAGATCGACCTCGAGGGCAAATCTGTGACCCTCAGGAACAACTCTGACAAGGTACTGAAGACTCAGACTGGGAAAATATGTGGGATTGCATAAAAGTATTCTTTGAAATCGAACATTTCTAATTTAAATGCTAGGTTTATTAGCATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAATCTGTGTATTTAATAACTCAATGCCATTTAAACATTTTAGGTTGCTTTAAAACACACCATTTCTAATGGTGATGCATGTTGGTTAACATTCTAGCCTAAAACAAAACCTAAAAAAAAAAGCAATTAATCATCATTTGTTTATTTAAATTCAGGATCAGTCTCTGGGCAGCTGGCGACTAAAGAGACAAATTGGAGACGGAG
Associated Phenotype:
Normal
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
quality PATO:0000001 |
normal PATO:0000461 |
Mutation Details
Allele Name:
sa12800
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000009438 | Essential Splice Site | 496 | 583 | 9 | 12 |
Genomic Location (Zv9):
Chromosome 22 (position 1195494)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 22 | 3110087 |
| GRCz11 | 22 | 3127360 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTATAAATTCAGCCCCAAGTTTGTCCTGAAGGCCGGTCAGACAGTTACGG[T/G]AAGCCAATTGGACCAGATCTCGTTAATTTCATGTATTTGAATGACGCTCT
Long Flanking Sequence:
GCAAATCTGTGACCCTCAGGAACAACTCTGACAAGGTACTGAAGACTCAGACTGGGAAAATATGTGGGATTGCATAAAAGTATTCTTTGAAATCGAACATTTCTAATTTAAATGCTAGGTTTATTAGCATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAATCTGTGTATTTAATAACTCAATGCCATTTAAACATTTTAGGTTGCTTTAAAACACACCATTTCTAATGGTGATGCATGTTGGTTAACATTCTAGCCTAAAACAAAACCTAAAAAAAAAAGCAATTAATCATCATTTGTTTATTTAAATTCAGGATCAGTCTCTGGGCAGCTGGCGACTAAAGAGACAAATTGGAGACGGAGAGGAAATTGTCTATAAATTCAGCCCCAAGTTTGTCCTGAAGGCCGGTCAGACAGTTACGG[T/G]AAGCCAATTGGACCAGATCTCGTTAATTTCATGTATTTGAATGACGCTCTTTTAGATGTTAAAGGTTTTGTTTTGTGTCAGGTGTGGAGCGCTGATGCTGGCATGTCCCATAGTCCTCCTTCAGACCTGCTGTGGAAGAGCCAGAGCTCCTGGGGAACCGGAGAAAACATCCTCACCCTATTGGTCAATTCAAGCGGAGAGGTGCAGTTGTTGTTGTTGTTATTATTAATAGTATTTGCCATTTTTCAATCATTTTTAATGTGTGAACCCCTTTCTCATTTAATAATCACTGTTTACAGGACGTGGCGAAGCGAACCGTCACAAAAAGCGTGATAGAAATGGAGAATGGTGACGATGAGGAGGGAGACTTTGGAGATGAAGACCTTTTCCATCAGCAGGTGTGTAAAGAATGACTCAATCCAAGTTTTATTTTTAATTCATATTCATCAAATACTGGCACGATCAGCAGGCTTGTGAAAAATGTAAAAGTCTTTACACTG
Associated Phenotype:
Not determined