Busch Lab

ZMP

LOC100332050

Ensembl ID:
ENSDARG00000007398
Human Orthologue:
LRRK1
Human Description:
leucine-rich repeat kinase 1 [Source:HGNC Symbol;Acc:18608]
Mouse Orthologue:
Lrrk1
Mouse Description:
leucine-rich repeat kinase 1 Gene [Source:MGI Symbol;Acc:MGI:2142227]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa13125 Essential Splice Site Available for shipment Available now
sa13011 Nonsense Available for shipment Available now
sa12644 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa13125
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000029668 Essential Splice Site 226 1389 4 25
Genomic Location (Zv9):
Chromosome 7 (position 10474921)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 9407984
GRCz11 7 9653148
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAGTTTGCCATCATCACCGGTTTGCCTCTGTATGCTGCGGCTCAGGGAGG[T/C]ACTGAACATKAWGAACGGAAATTTGAAATTTGTGTTGCCTGTTCATTTAC
Long Flanking Sequence:
TATAATATATGGTATATATTATAAAAATATTTATAAACTGATGTTTATGAAAAGTTCTTGACAATTAATGCAGCATTTGAACTTATTTATGGATCTGTTATGACTTTTATTTTGAAAATGAGCTGTTTAGGCCATCAGGATGCAGATCTGTTAACTAATTATTTTTTGCCAAATGATGCTGATATGTAAAGCAAAATTAAAGGACCCGCCCCTTTTTGATGTCTTTGCTTAAGTTGTTAGACATGCCCCTTTCTGCTGATTGGCTGAGAGAGTTATTTGTGAAAATATGAGTTCTTCTTGTGCTGCGTTTTTTCTTCAGGTCCGTGTGTGCGTAAGGATCTGCTGAACTGGATGTTGGCTACGGCGTCTCAGCAGGGTCATTTAGACGTGGTGAAGCTCCTGGTTCAGACGTATAATGCAGACGCAGACGGCTGTGCTGTTCATTCAGGAGAGTTTGCCATCATCACCGGTTTGCCTCTGTATGCTGCGGCTCAGGGAGG[T/C]ACTGAACATTAAGAACGGAAATTTGAAATTTGTGTTGCCTGTTCATTTACTAAATTTTTAAACTTTTGAAACTTAAAAAAATAGTCAAATTGACATGAAAAGTTAAAGAAAAAAAAAAAAAACATTCATTCAGATCATTTGATCCCTGATTCATATTGACTAACACATTGAACATTACATAAAAATTGTAGCACTTATTGTTTTATTAACTTAACAGTAATGGAAGTTTATAATTTAAATATAATGATCGTTTTAACCATGTTTTGCATGTTCAAGATTCTCTTGTGTTAGCTAGTGTTTGCGTGATGTACTGATAAAGATATAATGATAATGTTACTGATATTATACTGTTTGATTTTGGGGTTAAATTCATTGAAACCTTTTATAGTAATGTTCAGTATGTATATATATGTATGTATGTATGTATGTATAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAATTAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13011
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000029668 Nonsense 293 1389 6 25
Genomic Location (Zv9):
Chromosome 7 (position 10465178)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 9398241
GRCz11 7 9643405
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTGCATGTTGACTGGTCTGGACTGAAGCTGTCCTGGTTGGATCTGGACT[G/A]GTTTATGGACGWRTCGTCTCGCATCACCGTTCTGGATCTCTCTCGTAACT
Long Flanking Sequence:
GCTTCACATAATAGGTCATAGTTATGGCTTAAAGTATATCTAAAGTGCTATTCCATCATATGTAATGAGCAGTGGTTAATGCGTGTGGCTGCAGTTGTTGCAGCCTCTGCTTTAGGACACGGCAAACACTTGAACTCCGGTGTAGAAAAAAATGAGTTATGTCACACTCCCCCTTCCCAAACGAGTGACGCGCAACTACAGCCTGTCAGGTGTGTGGAAAGCACATGATGTGCGGTTCAAATCCAATCCCATCTCTAATCTTCAGTGCTAAATTCAACCTTGCGCTCATCATAACATCACAATTCACGAGACAACTTTTCACCTCGACGAGATATCTCGTTGCGATTTACTCTCGCTAGAGCTTGTAGCCCGACATCTCATCCCATCCCTACTCAGCACTAATTATTATAATTAGTTAATAAAATGTTTTGTCTGCCCTCATCCACAGGCTGTGCATGTTGACTGGTCTGGACTGAAGCTGTCCTGGTTGGATCTGGACT[G/A]GTTTATGGACGTGTCGTCTCGCATCACCGTTCTGGATCTCTCTCGTAACTGTCTGAGTTCACTGCCGTCTGTGGTGCCGTGGGGTTTGATTAATCTGCGCTCGCTCGATTTGTCCCAGAACCAGCTGAAAGAGCTTCCCACGCCAGCGTCCTCACAGCAGATCATCTGCAGCAGGTCAGTACAAGAATCGTTCACCAGACAAGCTTTTAAAGGGAACCTATTATGCAAAAATCACTTTTATAAAGAGTTTAAACACAGTTTTGTGGCAACAGTCTGTGGATATAACCATCTTCTAATGGTAAAAATATTCCTTTTTTATTATCACACTTGATAAAAACAGTCTACTGCAGTGGTAGGGAACATATGACTATCGAGCCACATGTGGCTCTTTGACTAAAAATACATGGCTCTCCAGCTGCCTTCCTTCAATAATATTTTACCATTTAAAATATTATAACGTCACTAAAAAATTAGTTTCCTATCGAAAATGCAATTACAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12644
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000029668 Nonsense 740 1389 15 25
Genomic Location (Zv9):
Chromosome 7 (position 10436167)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 9369230
GRCz11 7 9614394
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCCAGCATGTCGACGGTCAACCAGTGTTTCTTCACTGATAAAGCTCTGTA[T/A]ATGGTGATCTGGAATCTGGCTTTAGGAGAAGAAGCCGTGGCAAACCTGCA
Long Flanking Sequence:
GTTTAAAATGATTATAAATATGACTAAATTATACAAAATCTAAAAGTAAGCATATAATAAGGCATAAGTCTCAGAATCTTTTCTTCTATCATTGGCAATAATCTTAAAATCAATATTATATGAGAAAGTGTGACACACTCAAGCAAAACACAGCAAAGTGAGTATTTCTTGATTCATTTAGTTTTCCCACTGCACTTCATTTAAATACAACTTGTATTTACTAATAGAGATAGCTGATAAATGTACTTTTGTTTTATTAAACTAGATATGCCTGTCAAGTTGCTTTGAGAGTTTATTTTCTTGTAGTTGCATTGGTGATTAATAAAACACTATTAATATCTTCACTTCTTTACCTGATTCAGTTTAGAGGAGGAATGAATATGTTTGTTTGTGTTTTGGTCCACACAGGTAGATTCAGTCTCCTTTAATGTGTGGGACATCGGTGGTCCGGCCAGCATGTCGACGGTCAACCAGTGTTTCTTCACTGATAAAGCTCTGTA[T/A]ATGGTGATCTGGAATCTGGCTTTAGGAGAAGAAGCCGTGGCAAACCTGCAGTCCTGGCTGCTCAACATCGAGGTGAGAGAAAAGAGAGAACAAACTAGACAAACATCATTACAAACCATCTGAATAAATGTACAGTTGTGTATTGTATATTATTTTCCTTTATTTTAATACTAATATATTTTTAATCTTTTAATTTCTTAAAAGTTTGAATTAATAATAACTTCTCTTTTAATCCATATGTTGGTATTTGTTTCTTATTTCTGTATGTGTTTATCAAAATTCTAAATGTATTTATGCAGTTTATCATTTTAACTTTATTACTTCATTTTTAAAGGTTTCATTAAAATGCTATGAAGCTCTTTTGAATTGAATTGAAAAGAGAATTTCTGTATACTTCTGAGTGAAATGTATGGCTTAAAGTGACCGCTTGCTTTTTTAAATATGAAAACAGGTATATTTTATATACTTTATGTTGCATATATTAGTATTTTAGCAACTGC
Associated Phenotype:
Not determined