Busch Lab

ZMP

mc4r

Ensembl ID:
ENSDARG00000015515
ZFIN ID:
ZDB-GENE-021223-2
Description:
melanocortin receptor 4 [Source:RefSeq peptide;Acc:NP_775385]
Human Orthologue:
MC4R
Human Description:
melanocortin 4 receptor [Source:HGNC Symbol;Acc:6932]
Mouse Orthologue:
Mc4r
Mouse Description:
melanocortin 4 receptor Gene [Source:MGI Symbol;Acc:MGI:99457]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa122 Nonsense Available for shipment Available now
sa148 Nonsense Available for shipment Available now
sa149 Nonsense Confirmed mutation in F2 line Not yet available

Mutation Details

Allele Name:
sa122
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019555 Nonsense 19 326 1 1
Genomic Location (Zv9):
Chromosome 2 (position 28100714)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 28277199
GRCz11 2 27932835
KASP Assay ID:
554-1630.1 (used for ordering genotyping assays)
KASP Sequence:
ACACCTCACATCATCATGGACTGCATCATTCATTTCGGAACCACAGCCAA[G/T]GAGCTCTGCCGGTGGGAAAGCCCTCTCATGGTGACWGAGGATCAGCTTCT
Long Flanking Sequence:
TAGCTCACATCCATCAATCAGAGCAGCCTCTGATTGGTGCAGAAGACTGGAGGAGGAGCCTACGCTCAGCATGCCAGACCGTAGCAGTGGGGGCAAGAGCATCTCACTCGCCTGCCTGCCAAAGTGCCGTAGACACTCTGGAGACCGACTGCCTCACTCTTAATGCTGCATATTGCTGTTTGCACTTCAACAGAGTCAGTGTTTCCTGATTTAGTCAGTCAGCGCTGTCTCCCGTCCTCTGATTGTCTATTCTTCTTGTGTGGGAGGCTCTTTCTAGGACATTTTTGTCGCTTTGGAGGAAGAGTTATCGCAGAGGTGAGGTGACGGATGCTGACACAATACTTGCTTTCTCTGATCTACATGGTGGATGATGTTTCATCACACCTGCAAGCCTGATGAATTCACCAGACTGACTTAAACAGGGATCAATCAGACGATTCAAGGAAATGAACACCTCACATCATCATGGACTGCATCATTCATTTCGGAACCACAGCCAA[G/T]GAGCTCTGCCGGTGGGAAAGCCCTCTCATGGTGACAGAGGATCAGCTTCTGGATGCTACGAGCAGCTGCTGATCTCCACGGAGATCTTCCTCACGCTCGGCCTGGTCAGCCTCCTGGAGAACATCCTTGTGATTGCAGCCATCGTCAAAAACAAGAACCTACATTCCCCTATGTACTTCTTCATCTGCAGCTTGGCTGTAGCAGACTTGTTAGTGAGTGTCTCCAATGCTTCGGAAACAGTTGTGATGGCGCTCATCACTGGAGGCAACCTGACCAACCGTGAGAGCATCATTAAGAACATGGACAACGTGTTTGACTCTATGATCTGCAGCTCTCTGTTGGCCTCCATTTGGAGTTTGTTGGCCATCGCGGTGGACCGCTACATCACAATCTTCTACGCTTTGCGCTACCACAACATCATGACCCAGCGGCGGGCGGGCACCATCATCACCTGCATCTGGACCTTCTGCACAGTCTCCGGCGTACTCTTTATCGTGTAT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa148
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019555 Nonsense 31 326 1 1
Genomic Location (Zv9):
Chromosome 2 (position 28100750)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 28277235
GRCz11 2 27932871
KASP Assay ID:
554-0040.1 (used for ordering genotyping assays)
KASP Sequence:
GGAACCACAGCCAAKGAGCTCTGCCGGTGGGAAAGCCCTCTCATGGTGAC[A/T]GAGGATCAGCTTCTGGATGCTACGAGCAGYTGCTGATCTCCACGGARRTC
Long Flanking Sequence:
GTGCAGAAGACTGGAGGAGGAGCCTACGCTCAGCATGCCAGACCGTAGCAGTGGGGGCAAGAGCATCTCACTCGCCTGCCTGCCAAAGTGCCGTAGACACTCTGGAGACCGACTGCCTCACTCTTAATGCTGCATATTGCTGTTTGCACTTCAACAGAGTCAGTGTTTCCTGATTTAGTCAGTCAGCGCTGTCTCCCGTCCTCTGATTGTCTATTCTTCTTGTGTGGGAGGCTCTTTCTAGGACATTTTTGTCGCTTTGGAGGAAGAGTTATCGCAGAGGTGAGGTGACGGATGCTGACACAATACTTGCTTTCTCTGATCTACATGGTGGATGATGTTTCATCACACCTGCAAGCCTGATGAATTCACCAGACTGACTTAAACAGGGATCAATCAGACGATTCAAGGAAATGAACACCTCACATCATCATGGACTGCATCATTCATTTCGGAACCACAGCCAAGGAGCTCTGCCGGTGGGAAAGCCCTCTCATGGTGAC[A/T]GAGGATCAGCTTCTGGATGCTACGAGCAGCTGCTGATCTCCACGGAGATCTTCCTCACGCTCGGCCTGGTCAGCCTCCTGGAGAACATCCTTGTGATTGCAGCCATCGTCAAAAACAAGAACCTACATTCCCCTATGTACTTCTTCATCTGCAGCTTGGCTGTAGCAGACTTGTTAGTGAGTGTCTCCAATGCTTCGGAAACAGTTGTGATGGCGCTCATCACTGGAGGCAACCTGACCAACCGTGAGAGCATCATTAAGAACATGGACAACGTGTTTGACTCTATGATCTGCAGCTCTCTGTTGGCCTCCATTTGGAGTTTGTTGGCCATCGCGGTGGACCGCTACATCACAATCTTCTACGCTTTGCGCTACCACAACATCATGACCCAGCGGCGGGCGGGCACCATCATCACCTGCATCTGGACCTTCTGCACAGTCTCCGGCGTACTCTTTATCGTGTATTCAGAAAGCACCACTGTTCTCATCTGCCTCATCAGC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa149
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019555 Nonsense 186 326 1 1
Genomic Location (Zv9):
Chromosome 2 (position 28101216)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 28277701
GRCz11 2 27933337
KASP Assay ID:
554-0050.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGCATCTGGACCTTCTGCACAGTCTCCGGCGTACTCTTTATCGTGTATT[C/T]AGAAAGCACCACTGTTCTCATCTGCCTCATCAGCATGTTCTTCACCATGC
Long Flanking Sequence:
AGCTCTGCCGGTGGGAAAGCCCTCTCATGGTGACAGAGGATCAGCTTCTGGATGCTACGAGCAGCTGCTGATCTCCACGGAGATCTTCCTCACGCTCGGCCTGGTCAGCCTCCTGGAGAACATCCTTGTGATTGCAGCCATCGTCAAAAACAAGAACCTACATTCCCCTATGTACTTCTTCATCTGCAGCTTGGCTGTAGCAGACTTGTTAGTGAGTGTCTCCAATGCTTCGGAAACAGTTGTGATGGCGCTCATCACTGGAGGCAACCTGACCAACCGTGAGAGCATCATTAAGAACATGGACAACGTGTTTGACTCTATGATCTGCAGCTCTCTGTTGGCCTCCATTTGGAGTTTGTTGGCCATCGCGGTGGACCGCTACATCACAATCTTCTACGCTTTGCGCTACCACAACATCATGACCCAGCGGCGGGCGGGCACCATCATCACCTGCATCTGGACCTTCTGCACAGTCTCCGGCGTACTCTTTATCGTGTATT[C/A]AGAAAGCACCACTGTTCTCATCTGCCTCATCAGCATGTTCTTCACCATGCTGGCGCTCATGGCCTCACTCTACGTCCACATGTTCCTTCTAGCCCGGCTGCACATGAAACGGATCGCCGCCTTACCTGGAAACGGCCCGATATGGCAGGCGGCGAATATGAAGGGCGCCATTACCATTACTATACTACTGGGGGTGTTTGTGGTGTGCTGGGCGCCCTTTTTCTTGCACCTCATCCTCATGATCTCCTGCCCGCGGAATCCTTATTGTGTCTGCTTCATGTCACACTTCAACATGTATCTGATCCTCATTATGTGCAACTCGGTCATAGACCCGCTCATATATGCCTTCAGAAGCCAAGAAATGAGGAAGACCTTCAAGGAGATCTGCTGCTGCTGGTATGGACTTGCATCTCTGTGTGTATAAGTGCCGATTTTATTCTGACAGCACTTAGCAACTGGAAGATGCTGAGAATTTTGTGTATGGTAATTCTACTGTGCAG
Associated Phenotype:
Not determined