ZMP
si:ch211-15p9.2
Ensembl ID:
ZFIN ID:
Description:
hypothetical protein LOC562650 [Source:RefSeq peptide;Acc:NP_001038455]
Human Orthologue:
PDP1
Human Description:
pyruvate dehyrogenase phosphatase catalytic subunit 1 [Source:HGNC Symbol;Acc:9279]
Mouse Orthologue:
Pdp1
Mouse Description:
pyruvate dehyrogenase phosphatase catalytic subunit 1 Gene [Source:MGI Symbol;Acc:MGI:2685870]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa1211 | Nonsense | Confirmed mutation in F2 line | Not yet available |
| sa30658 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa1211
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000089777 | Nonsense | 44 | 505 | 2 | 2 |
| ENSDART00000142513 | Nonsense | 44 | 505 | 1 | 1 |
Genomic Location (Zv9):
Chromosome 11 (position 25280745)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 11 | 24109570 |
| GRCz11 | 11 | 24347186 |
KASP Assay ID:
554-1120.1 (used for ordering genotyping assays)
KASP Sequence:
CTGAACAGAGGTCAGTTCYACACAAAATCTACAATCTACAAGCCAGTCTG[T/A]GAAAATCCACTAATAATCAAAAACTCCAGAAGAAAATACAGCGTCAAGGC
Long Flanking Sequence:
CGCTGTTAACTATATGAATAGCGCGGACTTTGTACTTTCTCATTTCTTGAAATTCAGATTAAAACAACGTGTGAGGATGAGGAAGTAGGCCTATGAAATATACAAAATCCGGAAGAATATTTATTTGTTCTAACACACGTAAAGGTATCCAGTTGCATTTATATCTCTATATTTGTATTTGATGTTAAGAACTGAACAGCTGCACCTCCATTTAATAATACTGTAGTCGGCTTGTACTTTGTGGCTAAACTGTTCTGATTTAGTCACTGACATGTATATATTCAGTATCATTTTTTTAAACAGTAGCCTAAATTTAGAGTGCTTACATTAATTTGTACATTTACAGGTGCAGCTCCATCCAAAACATAAATGTCTCCAACTTCATTGAAGCACCTCAGACATCAGATGTCACTACAAAGATGGAGAGCAGCAACAGACGCCTGTTTGACTCTGAACAGAGGTCAGTTCCACACAAAATCTACAATCTACAAGCCAGTCTG[T/A]GAAAATCCACTAATAATCAAAAACTCCAGAAGAAAATACAGCGTCAAGGCAAATCAGATGTCACTCTCACAAATAAACCACACTTTAAAGGCCAGTGAATACAGTTTAAAAGTAAATGCTTATAATGGGTGTGTAAAAGGGTTTGACAGCAATATATTACCATCAAACTCTCCAAGCGAAGACAGACGGAGTGCTGCAACATGTCTACAGAACCGTGGTATGCTCTTCGGGGTCTTCGATGGTCATGCAGGGTCTGCTTGTGCACAAGCTGTTAGTGAACGCCTGTTTTACTACATAGCCTTGTCTTTGCTTCCATTGAGGACTTTAATGGAGATAGAGGCGGCTGTGGAGAGTAACCGGCCTGTGCTTCCAGTGCTACAGTGGCACAAACATCCCAATGACTACCAGAGCACAGATTCTGGCAAACTTTACTTCAGTAGTCTGAGGACATACTGGCAGGAGAGAATAGATCTTCAAGAGAATGAGGATTGTGATACACA
Associated Phenotype:
This allele has been associated with this phenotype by genetic linkage analysis and may not be causal.
See FAQs for more info.
See FAQs for more info.
| Stage | Entity | Entity | Quality | Tag |
|---|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
eye ZFA:0000107 |
decreased size PATO:0000587 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
head ZFA:0001114 |
malformed PATO:0000646 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
swim bladder ZFA:0000076 |
aplastic PATO:0001483 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
trunk ZFA:0001115 |
anterior region BSPO:0000071 |
bent PATO:0000617 |
abnormal PATO:0000460 |
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
anterior/posterior axis BSPO:0000013 |
increased length PATO:0000573 |
abnormal PATO:0000460 |
Mutation Details
Allele Name:
sa30658
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000089777 | Nonsense | 332 | 505 | 2 | 2 |
| ENSDART00000142513 | Nonsense | 332 | 505 | 1 | 1 |
Genomic Location (Zv9):
Chromosome 11 (position 25279883)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 11 | 24108708 |
| GRCz11 | 11 | 24346324 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGTGAAACACGACAGGCTATTAGGCCTGTTGATTCCTTTCAGGGCTTTT[G/T]GAGATATGAAGTTTAAGTGGAACAGTGAGCTCTTGAATCGCATCTACGAG
Long Flanking Sequence:
CTGTGCTTCCAGTGCTACAGTGGCACAAACATCCCAATGACTACCAGAGCACAGATTCTGGCAAACTTTACTTCAGTAGTCTGAGGACATACTGGCAGGAGAGAATAGATCTTCAAGAGAATGAGGATTGTGATACACAAGGAGCTTTTAGAAATGCTTTCAAGAGATTGGATAATGATATTTCTTTGGAGGCCCAAGTGGATATTGGGGTTCCTTTAGCTCATTTCACCCCTCTAAGAGTGGCTCTATCTGGATGTACAGCTTGTGTGGCTTATGTGGATCAAGATGATCTTTATATTGCCAATCTTGGTGATAGTAGAGCAGTTCTCGGGGTCCAACAGGGTGATGGGAGTTGGTCTGCTTTTACCATTACAAATGACCACAATGCCCAAAACCCAAATGAGATGAAACGTGTTCTGTCAGAGCATCCAGCTTGTGAGCAGAAGACAGTGGTGAAACACGACAGGCTATTAGGCCTGTTGATTCCTTTCAGGGCTTTT[G/T]GAGATATGAAGTTTAAGTGGAACAGTGAGCTCTTGAATCGCATCTACGAGGCACGGCCCGAGCTGCTGATTGGCAATGAAAATGCAAAAATGCTGCCAGCAAACTACCACACACCTCCTTACCTCACTGCAGAGCCTGAAATCACTTATCACAAACTGCGACCTCAAGACAAGTTCTTGATTCTGGCTACTGATGGACTCTGGGAGTTGATGCACAGGCAGACCGTTGTGCAGGTATTAGGAGAACACTTGTCTGGGATTGAGTGGAAGAAACCGGTTTCTGGGATGTATTTCACGGTGGGACAGATGCACAGACTGCTGCGGGAGAGGAAGAGAAGAGCTCTTTCTGCTCGGGAGGATGAGAACAGTGCTACTCATCTGATTCGTCACGCTCTGGGCAGCGATGGTTCCGGCACCATTGAACTCGATCGCATTGCCAAAATGCTCTGTCTCCCACAGGATTTGGTAAGAATGTACAGAGATGATATAACAATTATAGTG
Associated Phenotype:
Not determined