ZMP

si:dkey-220h13.7

Ensembl ID:

ENSDARG00000010977

ZFIN ID:

ZDB-GENE-091118-61

Human Orthologue:

RAB34

Human Description:

RAB34, member RAS oncogene family [Source:HGNC Symbol;Acc:16519]

Mouse Orthologue:

Rab34

Mouse Description:

RAB34, member of RAS oncogene family Gene [Source:MGI Symbol;Acc:MGI:104606]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa7306	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa12037	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa7306

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000004740	Essential Splice Site	46	259	2	10
ENSDART00000141382	Essential Splice Site	47	254	3	11

The following transcripts of ENSDARG00000010977 do not overlap with this mutation:

ENSDART00000144176

Genomic Location (Zv9):

Chromosome 21 (position 25464191)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	26034009
GRCz11	21	26070704

KASP Assay ID:

554-4438.1 (used for ordering genotyping assays)

KASP Sequence:

ATGGCTTCAATATTACTGTTAGAGAGGCTTGTCAAGGGCAGAAAACAGGG[T/G]AAGTTATACTTGACACAGAAACGACAGTTTGTAATTTAGTTTTTAAGTTA

Long Flanking Sequence:

ACATTATATAATTATTATTATTATCACCATCCTCATCATGGTTATTATGTATTTCTTCCCAGAAGGACAGAATGGTAGAGTGTTTGTGGTTGTGTCAATGTGCTCTTGTTAAAGCTCTCACATGATGAATTCTTTACCCCCTGTGAAAGGAGACCGGATCATCTGTGAACTCCCTTTGGTAACATTTTCTGTATTACTCAGTTATTCATTCAGTCTCTGTGAACATTCAGCCATGTTTATATATTTTCTTTTTTTTTTAACCTCAGAATTAAACACTTCCTTATAGAGGATTATAACATTGAATAACCCTCTGAGCTTAATAAGCCAGACTCAGCCAGAGCAGATTGTCATGTAACAGGTTTTGTTTTTTTCTTGTTTTAAAACTTAACCTCATCTAAATTGGTCTATTTTTTCAGTATTTTACAAGAGATGCTGCAGTGCACACCAAAGATGGCTTCAATATTACTGTTAGAGAGGCTTGTCAAGGGCAGAAAACAGGG[T/G]AAGTTATACTTGACACAGAAACGACAGTTTGTAATTTAGTTTTTAAGTTAATTTAGTTAGAGTTTTGTAAAGTGAAGGGAAAACATTTGCAGTTGGGCAGTGATTTATCGAATATGTCAACATTTTACATGTCCCAGTACCTGTACATTACTACAACACTAAAGGCTACAGTTAACACAATATTACCATTGGTATTCAAAGCAATTTTTACAATAATGCCTAAATCAATTTTGAAAATCAATTTCTCATAATTGCACATTGTTGAAATACATAAATTTAGATAGTGGCTTTCATGATATGTGTTCTTGTTTGGGCTAATGCAGTGCAAAGTGCTCTTACTAAAAGATTGACTTTAGGAATTAAGAATTTATAATAGATCAAATGAAGGTCTATAAAAGTTGAAGTTTCAAATATATATACTTCAAATATGTACCTTCTGCACATGCAGAAGTTAATACAATGCTGTTTTTTTGTTTTGTTGTAATCCTATACATAGAAAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa12037

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000004740	Nonsense	149	259	7	10
ENSDART00000141382	Nonsense	144	254	8	11

The following transcripts of ENSDARG00000010977 do not overlap with this mutation:

ENSDART00000144176

Genomic Location (Zv9):

Chromosome 21 (position 25460403)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	26030221
GRCz11	21	26066916

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

AAATAATCATGAATGGTGTTTGTTTTCTGTGTCTGTTTATTCAGAGAWTG[G/A]MTTGAAGATGCCATGAGGGACAATGACCCGTCCAGTGTCCTGCTCTTCCT

Long Flanking Sequence:

AGAAAAGAAAGAAAGAAAAATGAATGATTTGTCTTTTTCCCACAAGATTCTGCAAAGACTCATTTGACAGAACGTACAAGGCAACTATTGGAGTGGATTTTGAGATGGAGAGATTTGAAGTTCTCGGGGTACCCTTCAGTTTGCAGCTGTGAGTTTTTTTTAATGTATTTTATTGGTTTATCTGTCATTCACTTGGTTTCAGCCAATCATGTCTTTCAATACAGGTGGGACACAGCAGGTCAGGAAAGATTTCGATGCATTGCCTCCACATACTACAGAGGAGCGCAAGGTGATAAAACAGACTATATCAATCATAATCTTGCTGTCAGTAGAGTTCAAATGTTTTGCTTTTCTGTTCCAGCCATCATCGTTGTGTTTGACCTGAGCAACTATGAGTCTCTGGATCACGCGAGGTACAGTTGAAGCTGTTATTGTGGTTGAAATACATCTAAATAATCATGAATGGTGTTTGTTTTCTGTGTCTGTTTATTCAGAGAATG[G/A]CTTGAAGATGCCATGAGGGACAATGACCCGTCCAGTGTCCTGCTCTTCCTCGTGGGAACCAAGAAGGATCTTAGTGTGAGTAACTCTCACATGATCTATCGCTGAAAAAAAGTGTCCTAAAAGTTCTTTTTTGTCTGTGAGTTATTTTATTCCATTTGAATGGTTATAACATTATCAAAAAGGTCAAAAGAAAAGAAAAGTTTACCCCAAAAATGAAAATTTCCTCTCCATTTACTCACACTAAAGTGTTTTTTTTTTATTTCTTTTTTCTGTTGAACATAAAGGCAGATGTTCTGCTGTTGGAAAAAAGCAGTCAATAATCCATAGTAGGAACAAAAATACAATGAAAGTCATTGGTTGTTTTATTCCAACATTTTGGGACAAGTGGAGGATGAGTAGAATTTTCATTTTGGAGTGAACTATTCCTTTTTATTGACTTTTATTTCTTCTTTTTTAAAAATCTGTTTACTTTTTTTTTTTTTGTCAAAAAATAACTTAGT

Associated Phenotype:

Not determined