ZMP
notch1b
Ensembl ID:
ZFIN ID:
Description:
neurogenic locus notch homolog protein 1 [Source:RefSeq peptide;Acc:NP_571377]
Human Orthologue:
NOTCH1
Human Description:
notch 1 [Source:HGNC Symbol;Acc:7881]
Mouse Orthologue:
Notch1
Mouse Description:
Notch gene homolog 1 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:97363]
Alleles
There are 10 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa1187 | Essential Splice Site | F2 line generated | Not yet available |
| sa26617 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa26616 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa11236 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa1187
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000050855 | Essential Splice Site | 44 | 2465 | 2 | 34 |
| ENSDART00000050856 | None | None | 1817 | None | 22 |
| ENSDART00000130888 | Essential Splice Site | 2 | 2436 | 2 | 34 |
Genomic Location (Zv9):
Chromosome 5 (position 68766852)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 65099074 |
| GRCz11 | 5 | 65778189 |
KASP Assay ID:
554-1096.1 (used for ordering genotyping assays)
KASP Sequence:
AAAACGGAGGCACATGTGAACCAACTGCAGACGGGAGAGGAGAATGCAAG[T/A]AAGTGATAAGATTCTCGACTGCATGATATTGCTGTGTCTGATACCCAGAA
Long Flanking Sequence:
TATTTCATGTTTAAGGCAATACAAATAACATATTCTTTGGCATAATAGTGAAAGTGCTAAACCTACACACATTTTAGAAGAAAATTTCAGGTTTTTGCATCCGAACTCAACTCACTTTTTAAATTAGGATGACTGCTTTTGGTCATTTATAATAGACTGTAAACAAATGCTGGGTTCCTTTACAATCAATTTGTGTCGGGACATCATGAAGCTATTAAGTTAGCTAATTAGTTTTCACAAATTGAAGTGGATTGGATATAAAACAATTAACTTATCCCCAAAACAACTAAAACATTGTGTTGTTTCAGCTCATTTTAAATAAGTAGTTTGAACAGACGGCAAACATCTTTTTTTTGTGTGTAGTTTGAGATCAAAACATCATGTAATGCTCAACAGAAATGAGTTATCCTGTTTCTGCATTTCCAGGCCTGGAATGTTCAGAAAAATGCCAAAACGGAGGCACATGTGAACCAACTGCAGACGGGAGAGGAGAATGCAAG[T/A]AAGTGATAAGATTCTCGACTGCATGATATTGCTGTGTCTGATACCCAGAAGGAGTCAAACATATTGTTGATTGAATAGCACACACATACAGTAGCTAAGGAGATTTTTAAAAGTTAAAGAGATAGTTCACCTCAAAATGATGTTTACTCACACTTGACTTGTTCCAAACCAGTTTAAGTTTCTATTTGACACTAAAGAAGGTATTTTGAAGAATTTTACACCGTAAAAAAATGTTTGGTTCCAAATAATCAATTTATCTTGGGACAACATGAAGGAATTAAGTTAAGGTAATTAATTTTTACAAATTCAGGTGGATTGAACTTAAAACATTCAAGTTGTCCCAGAATAAAACCTCAAGGATTGTGTTGTTCCAGCTCAATTTAAATAAGTAGTTTTGCCGTAAACATATTTTATGAGTGAAGAAACCTGTAACTGACACCATAGTGTTTGTTTTTCTTATAGTTGTCAATGGTTTCAACATTCTTCAAAACAGTGGCGAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa26617
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000050855 | Essential Splice Site | 539 | 2465 | 11 | 34 |
| ENSDART00000050856 | None | None | 1817 | None | 22 |
| ENSDART00000130888 | Essential Splice Site | 470 | 2436 | 10 | 34 |
Genomic Location (Zv9):
Chromosome 5 (position 68714956)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 65047178 |
| GRCz11 | 5 | 65726293 |
KASP Assay ID:
2259-6806.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTGGAGGAATGAAGCTGGAGGAATTATTGTAATGACCTTCTTTTTTTGT[A/T]GGATTTTCGGGGAGCCAATGCCAGTTCGACATTGACGAGTGCGCTAGTAC
Long Flanking Sequence:
TGTCCCATAAGTCTATACCCTGATGGATTTGTAGCCGTTAATGTGTTCAGACTGTATATTTGAGCAGCAGACGTCTTTAGTGAGGGATTAAAATAACTGGGGGAGAAAGCACAAATGCTGGGGGTCCCTGAGCGACGGGGAGCTGCTGAATAGCATGGGGTCAGGGGTTGCGCGGGGCTCTTTTTGGTGGGACAGGCTCGAAGAGGGGGGCGAAGGCTGGATGGAAGAATGCACATTGTGATGGAAAACTTCCACGGGACAAAGGAGGCAACCGGCATGGCTTGGCGTTCCTATGAATAGACAGTTCCTCTTTGTCTGGTGCCCTTGGTCAGGAGGGTTTTTTACCGCCATTTTACCCCCTCTTCTCCCACTCTCAGAAAAAAATAAGCTTGAAAACCTGAGAGAAAAAGCATGCAGCTGGGTATTAATGAATGCTGCTGTATAGAGGAGTGTGGAGGAATGAAGCTGGAGGAATTATTGTAATGACCTTCTTTTTTTGT[A/T]GGATTTTCGGGGAGCCAATGCCAGTTCGACATTGACGAGTGCGCTAGTACTCCTTGTAAAAATGGGGCCAAGTGTATGGATGGGCCCAATATGTACACCTGCCAGTGCACTGAAGGTATGAAGATGCCATCAGCTTCTAATTAGTACTAAAAAGTATTAAAGAAATGGAAAAATTATTTTTTTGGCTATTTGGGGGGGGGGTATACATATTTTCAAATATTTCACAAATTATGTTTAACAGAGGAACACATTTTTCACAGTATTTCCTATAATATTTTTTCTTCTGGAGAAAGTCTGATTTGTTTTATTTCGGCTAGAATAAAAGCAGTTTTTAATTTTTATTTCAATATTTAATTCTCTTTGAATATCACACTAACTAACTGTACAAAAAAAAAAAAAAAAAAAAAAAACTACTAACACTTTCCTTCTTAGACTTTACAGACCTGAAACTTGCCTTTAGTACTTATTCATTGTTGCTCTTATAGTTGTGTAAATTGCTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa26616
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000050855 | Nonsense | 1088 | 2465 | 20 | 34 |
| ENSDART00000050856 | Nonsense | 439 | 1817 | 8 | 22 |
| ENSDART00000130888 | Nonsense | 1059 | 2436 | 20 | 34 |
Genomic Location (Zv9):
Chromosome 5 (position 68696569)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 65028791 |
| GRCz11 | 5 | 65707906 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTTATACTGTGACGTTCCCAGTGTTTCCTGCGAGGTGGCCGCCAAACAG[C/T]AAGGTTTGTTTATATGAATGGGCCTATTACAGTTAAAGTCAAATTTATTC
Long Flanking Sequence:
TAATGTTAATTAATGCATTTACTAACATGAACAAACAATGAGCAATACATTTACTACTGTATTTGTTCATGTTAGTTTACGTAAAATAAAGTTGTTCATTGTTAGTTTGTTAACTCATGGTGCATTAGCTAATGTTAACAAGCATGGACTTGGATGTTAATTATGCATTAGTAAATGTTCAATTATGATTATTAATTGCTGTACATGTGTTGTTCATGATTAGTTCATGTTAGTAAATGCATTAACTAATGAACCTTATTGTAAAGTGTTACTATATATATATATATATAATTTTTTGAGTGTGGATACACTAGTTAAATCATTGACATGGATGAACTGTTGTCTTGCAGGAGCTGGTGAACTGGTGTAAACCGTCTCCCTGTAAGAATGGAGGGATCTGCAGACAGAGCGGCACGAGATACAGCTGTCAGTGTCAGACAGGCTGGACTGGTTTATACTGTGACGTTCCCAGTGTTTCCTGCGAGGTGGCCGCCAAACAG[C/T]AAGGTTTGTTTATATGAATGGGCCTATTACAGTTAAAGTCAAATTTATTCGCCCTTCTGGGATTTTATTGCCAAATGATGTTTAATAGAGCAAGGCAATTTTCACAGTATGTCTGATAATATTTTTTCTTCTTATTTGTTTAATTTCGCCTTGAATAAAAGCAGTTTTTAATTGTTTTAAAACCATTTTAATGCCAGTATTATTAGCCCCCTTAAGCAATATTTTAATTTCGATTATTATGTATATGTCTAATTAACCTAACCTGCCTTATTAACCTAGTTAAGCCTTTAAATGTCACTTTAAGCTGTATAGAAGTGTCTTGAAAAATATCTAGTCAAATATTATTTACTGTCATCATGGCAAAGATAAAATAAATCAGTTATTAGAGATGAGTTATTGAAACTATTATGTTTAGAAATGTGTTGAACAAAAAAAATCTCTCTGTTAAACAGAAATTGGGGAAAAATATACAAAATATACCCCTTGTTACTCAGCACTGG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa11236
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000050855 | Nonsense | 1149 | 2465 | 21 | 34 |
| ENSDART00000050856 | Nonsense | 500 | 1817 | 9 | 22 |
| ENSDART00000130888 | Nonsense | 1120 | 2436 | 21 | 34 |
Genomic Location (Zv9):
Chromosome 5 (position 68695835)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 65028057 |
| GRCz11 | 5 | 65707172 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCRTGCCAGAACGGAGCAACTTGCACCGACTACCTGGGCGGATACTCCTG[T/A]GAAGTMAGTCAAGAGGATCTGGAAGTTRGCAATCATCTTCACTGTGAATG
Long Flanking Sequence:
TTATTATGTATATGTCTAATTAACCTAACCTGCCTTATTAACCTAGTTAAGCCTTTAAATGTCACTTTAAGCTGTATAGAAGTGTCTTGAAAAATATCTAGTCAAATATTATTTACTGTCATCATGGCAAAGATAAAATAAATCAGTTATTAGAGATGAGTTATTGAAACTATTATGTTTAGAAATGTGTTGAACAAAAAAAATCTCTCTGTTAAACAGAAATTGGGGAAAAATATACAAAATATACCCCTTGTTACTCAGCACTGGTTTCTGCTCAGCCTGTTCAGTGTTTGAGATGTTTGTTTCTCCTGATTTCCAGGTGTTGATGTGGTCCGGCTGTGTCGTAACTCTGGCCAGTGTCTGGACGCTGGAAACACACACTATTGTCACTGTCAGGCCGGATACACGGGCAGCTACTGTGAGGAGCAGGTGGACGAATGCATTCCCAATCCGTGCCAGAACGGAGCAACTTGCACCGACTACCTGGGCGGATACTCCTG[T/A]GAAGTAAGTCAAGAGGATCTGGAAGTTGGCAATCATCTTCACTGTGAATGGTCCCTTTTCACATATCCGGGTTTCTTAGTTGCGGAAGTCGTCATAGTTGGGTAAACTTAGAGCATGGTAAACGGGAGAGAACAACAAATATTTTTTACAATCCTATTTGCTGAAATAATAACAGAAAAACTCCATAAGGATGTTATAAAGGTGTTCTGACAAAGTAAAAAAAAATAGTGTGTCAGCCAGAAGAGAGAATAACGTCAAATCACCTAACAGCAAGAAGGTCGCTGGTTTGAGTCCCAGCTGGGTCAGTTGACATTTTTGTGTGGAGTTTGCATGTTCTCCCCATGTTGATGTGGGTTTCCTCCGGGTGCTCCGGTTTAACCCACAGTGCAAAGACATGCGCTATAGGGGAACTACCAACCTACGTCACACATGATGTCACACGGGTTCAACCACACAAAGTGGTTACAAAAAAAAGACCGGTTCCAATAGCAAACATGTTG
Associated Phenotype:
Not determined