ZMP

upf1

Ensembl ID:

ENSDARG00000016302

ZFIN ID:

ZDB-GENE-040426-2836

Description:

regulator of nonsense transcripts 1 [Source:RefSeq peptide;Acc:NP_998639]

Human Orthologue:

UPF1

Human Description:

UPF1 regulator of nonsense transcripts homolog (yeast) [Source:HGNC Symbol;Acc:9962]

Mouse Orthologue:

Upf1

Mouse Description:

UPF1 regulator of nonsense transcripts homolog (yeast) Gene [Source:MGI Symbol;Acc:MGI:107995]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa39953	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa7535	Missense	Mutation detected in F1 DNA	Not yet available
sa11856	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa39953

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000021011	Essential Splice Site	304	1100	7	24
ENSDART00000138047	Essential Splice Site	304	557	7	13

Genomic Location (Zv9):

Chromosome 2 (position 56404057)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	2	56067125
GRCz11	2	56190970

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ATGTTCATGCTTCTGTTTTCTCTTTGTTCATCTTCCTGTATTTTCACTCC[A/G]GACTCAAGACAATATAACAGTGAGGTGGGATTTGGGACTGAATAAAAAGC

Long Flanking Sequence:

AGGAACGCTTTCTCTGCCATTCCAGATGACTTTATTAATCAGTGATTTGAGTCATGTCAGAGATGTATGGATGCAGTCCTCCAAGCTCATGATGGAGTCAGACACAATATTCATTCTGTCTCCACTGCTCCACTGGTCAAATAAGTGTAATCTAGAGGCCTCTGCCTTTGATATAAGCCACTTCTGATGCAAAATGATCAACTAGAAGTCAAGTTATTATTTGTTGCTTCTAAAACTTGGGTAGGCGACAGGACTTTTGTCAGGTAGTGTATATTGCATCATTAAAACTGATTGAGGTCATGTCAAAGTGTTGTGCGATGAGTCGATTGTGACAGGCCTACAGATGTGTTTCCTATCTCTCTTGATGCGCGAGTTTCTTGCTTATTAGTTAAAAAGATTTTCTAAAAATGTCTGAATGATTCTTCCATGTACAAAATCTGATTTAATTACATGTTCATGCTTCTGTTTTCTCTTTGTTCATCTTCCTGTATTTTCACTCC[A/G]GACTCAAGACAATATAACAGTGAGGTGGGATTTGGGACTGAATAAAAAGCGGATAGCTTATTTCACTCTGCCCAAGACGGATTCAGGTGGTAATATTTACTTTCAACATCTTCTGTGTCTACCAGTGGTTCATATCCATCCCATCCCTAACACCGAGTCCCATGCATCCCTCATCGATGTGTGCACGGACCTGTCTGCCCGAGTGTGTGTATGTGTGCGCGTGTGTGCTTTAGGGATGTCAAACTTGTTAGTTTCTTCAATGCATTGTGCTGAAGATTCAGTATGGATTCAGTTCAGTAATAAAAGCTGAACATTAGGCTTTAGTGAAATATGACCAGTCCAAAACATACTGGTCCCATTTATCATATATGCACTATAAACATAGGCGTGTAAGTAGCCATTCATCAGCGCGCAAAAAAGCAAGCAGGGAAAATGTTGGTAGTCCACATTTATTATGCGCTTTTATAATTTACTTGCATTTGTTCAAATCACTCCAGTTG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa7535

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Missense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000021011	Missense	451	1100	10	24
ENSDART00000138047	Missense	451	557	10	13

Genomic Location (Zv9):

Chromosome 2 (position 56412049)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	2	56075117
GRCz11	2	56198962

KASP Assay ID:

554-4152.1 (used for ordering genotyping assays)

KASP Sequence:

CATCAAATGCCAGCTACCYAAACGCTTCACTGCGCAGGGCCTGCCAGACC[T/C]CAACCACTCGCAGGTACAGARATGWACAAACTSRCATCTYTCTCWTAACT

Long Flanking Sequence:

ATAACCATGCAATTACAGTAAGACCAAAAGCTTTTTACAGTCAAACGTTTTAGAAAACCATTGGCAAAATGCATAATTACAACTTTTGCTCTGTTAAACACAAAGCTGTCATACAACTTTACATTAGTTATTCCTAATACAATAAGGCAGAAAAGGAAGAAAAACAATTACTATAAATCAGACAAATGCAAATAGAAAAACAATCAAGGTCACGGTTTATACCTGGAGATGTAGTCACTGTAATCATCATTGTTTGTCATTGCATAGAAAAAAAACTGTGTGTGTTAATTTTCTGATGAGCTCTCACTTCAAGTAGCCTCATGATCTCAGCTTTATGTTTGTGGTGTAATGTAGAATGCAGAGCGCCCTGAAGACGTTTGCTGTGGATGAGACCTCTGTGTCAGGCTACATCTACCACAAGCTGCTGGGTCACGAGGTGGAGGACGTGATCATCAAATGCCAGCTACCTAAACGCTTCACTGCGCAGGGCCTGCCAGACC[T/C]CAACCACTCGCAGGTACAGAAATGTACAAACTCGCATCTTTCTCATAACTTTCTTGGGGCTCGAGTGTTGGCATGGGCCCGTATAAGACTCTGATGGTATGATAACCTTGGATAAAAAGGTCACAATATTGTGAATACATCTCTAAAATATGTTCTTTTTAAATGTTTTACTTTTAAAACAAAAAAATAAATCTTTTACTTTTACTGCTACTTTTTGTCCTCATTAAACACATTATTTTTAATTTTAAGCAACATTTATACTATTTTGGTGCAGTAAACATGTCAGGCTAAATAATTGAAATAAAGCTTTGACTTCTGCTGTCTTCATTAGTTTCAAAAACACAGATTTCTTAAAGATAATAATAATTCCTTACATTTATAAAGCGCTTTTCTGGGCACTCAGTGCTTTACACAATGGTGGGGAATCTCCTCATCCACCACCAGTATGCAGCATCCACCTGGATAACGCGACGGAAGCCATTTTGCGCCAGACCGCACAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa11856

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000021011	Essential Splice Site	906	1100	20	24
ENSDART00000138047	None	None	557	None	13

Genomic Location (Zv9):

Chromosome 2 (position 56435088)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	2	56098156
GRCz11	2	56222001

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

ATATACATMRAAGGCCATRAAGTCCATCTGACAGTGTWAATGTTTGTTTC[A/T]GGGAGCCCGCTTCATGAGTACCGCCATGTATGATGCAAGGGAGGYCATGA

Long Flanking Sequence:

TCAGGTTCTATCTGACATTTTTGTCAAAATTGAGTTATAGACATATTCTTATTAAATGACAACTTATTTACATTTTTTATAAGTTTTTTATAAGTTGTTTACATTTAAAGACTTTTTATTTAAAAAATAAAAAAGATTTTATCTACAAAATTAAACTCTAGCCTGCATATCAAATGCACACACAAGGACCAATCAGGATCAGCTTTCTTTGTCAATTTTCCGGACTGCAACATTGACAGTGGAAAAGACCAAAAGAAATACAAAATCATTAAAGTCAACTAAATAATGCTGCACCACGCAAAATTAAGAAGAAACCTAAAACTGAAAAGATGTGTGTAAATGTGATGATTTGGAAGCTTTTTTTTTTTTACATTGAGATGAAATGTTAAACTTGACATTGTTGAATATAATGTAATATAAGGTGAAATATTTTTATTTGTGTGTGTGTGTATATACATCAAAGGCCATAAAGTCCATCTGACAGTGTTAATGTTTGTTTC[A/T]GGGAGCCCGCTTCATGAGTACCGCCATGTATGATGCAAGGGAGGCCATGATTCCTGGATCTGTGTATGATCGCAGCAGCACTGGTGAGAAACTCATATTAAAGTTTTCTTAGCAGTGGACAATTAGGGGAATGATCATGTTGCCTTGGTTCATTTTATCCGCTAGCTCATTGATCCTCAACCACCGGTCTGTGGGTTAATTGGTACCGGGCTGCACAATAAATCAATAATTATTTCCGTTTTATTTATTTTCTGAGTCTAAACAATCTTTTATTTTAAAAGTCTTTTATTTTGAAAAATGACCCTATTCTCACGGTCACTTGAGCACCCAAATTGAGCCCACAAGCAGCAAAATGTGTAAGAAACAGTCAGTGGAAAGTTTCTTTGCTAAGGGAAAAAGGCCCAGTGAAGGACCCGTAAACTGCCAAGGAATGGATCCACAACCCATTTGTCAACAAATCCAGCATGTCTCTGCAAGAAGGTCAACTGATGGAGGTCGCA

Associated Phenotype:

Not determined