ZMP
nos1
Ensembl ID:
ZFIN IDs:
Description:
nitric oxide synthase, brain [Source:RefSeq peptide;Acc:NP_571735]
Human Orthologue:
NOS1
Human Description:
nitric oxide synthase 1 (neuronal) [Source:HGNC Symbol;Acc:7872]
Mouse Orthologue:
Nos1
Mouse Description:
nitric oxide synthase 1, neuronal Gene [Source:MGI Symbol;Acc:MGI:97360]
Alleles
There are 8 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa33543 | Essential Splice Site | Available for shipment | Available now |
| sa26415 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa20353 | Essential Splice Site | Available for shipment | Available now |
| sa14542 | Essential Splice Site | Available for shipment | Available now |
| sa12337 | Nonsense | Available for shipment | Available now |
| sa11824 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa33543
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000099810 | Essential Splice Site | 278 | 1431 | 2 | 28 |
| ENSDART00000099822 | Essential Splice Site | 278 | 1431 | 2 | 28 |
| ENSDART00000125435 | Essential Splice Site | 278 | 1431 | 2 | 28 |
Genomic Location (Zv9):
Chromosome 5 (position 13294196)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 11705907 |
| GRCz11 | 5 | 12206124 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGACAACATGCCCACGGTGCTTAACAACCCTTACTCAGAAAGTGACAAGG[T/C]AAAATACAGTCTAAATGGCTTTATGTGTGGCTTTGAAGGACTGTGAGTGA
Long Flanking Sequence:
AAATGTCATTTCTGATTTACTCAATTTTCAATTATTTCAAACATTTATGAATTTCTTTCTTCTGATGGACACAAAGATATTTTGATAAAAAAAGTGTTAGAAACCTGTAACCATTGACTTCCATAGTATCTGTTTTTTCCTACTATGAAAGTCAGTTGTTACAGGTTTTCAGCATTCTTTAAAGTATCTTCTTCAGAGTTCAGCGAAGGAAAGAAACTCATAAAAAACACTCAATGGTTTGAAAATAATGAATAACTTTTCATTTTTGGCTGAACCATCCCTTTAATCGAATTCACTTCTCTTCTCTGTCTCTTCACTTGTTTTCTTCTGGCTGCTGTTTGAACTGCAAACTGAACTATTTGTGACTTTCAGAGACCTTGGTGTGGGAAATGGACAGAACGCCCAGCTGGCATCGGATAACGACAGAGTGTTTGATGACCTCTGGAGAAAGGACAACATGCCCACGGTGCTTAACAACCCTTACTCAGAAAGTGACAAGG[T/C]AAAATACAGTCTAAATGGCTTTATGTGTGGCTTTGAAGGACTGTGAGTGAGTCAGGAATTTACTGTATTACTTACTTCTCTGTTTTAAAGCTGCAGGTTAGGAAATATTGAAGCTGTATTTACTGTGTATATGCTTTGGTTTGCTTGGAAGCTGGCATATTCTCAGTGTTCTGCTGTCATTTTAAAAGAATTACAGGACATTTAGTTTCGCAAAATAACTTTATTATTAAATTCTTTCACTGGGCATTTAAAACAGTGGTTCTCAACAGGTTTTTCCTTTTTGGGATCCCAGGCAGCAGAGAAAATTAATGCTATTTCTACTAATAATAAAATGACCACTAATAAAAATGCAACTAACTCTATAGGAACCAAACCAAAAACTTGACTATTACAGTGCATCCGGAAAGTATTCATAGCGCTTCACTTTTTCCACATTTTTTTGTTACAGCCTTATTCCAAAATTTATTCAATTAATGTATTTCCTCAATATTCTACACACA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa26415
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000099810 | Essential Splice Site | 505 | 1431 | 7 | 28 |
| ENSDART00000099822 | Essential Splice Site | 505 | 1431 | 7 | 28 |
| ENSDART00000125435 | Essential Splice Site | 505 | 1431 | 7 | 28 |
Genomic Location (Zv9):
Chromosome 5 (position 13251767)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 11663049 |
| GRCz11 | 5 | 12163266 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCCCGATGGATCAATTCTAGGAGATCCAGCTTCTGTAGAGCTTACAGAG[G/A]TGAGATTGATGTCGTTTTGATTGTTAGGCTCACAGACACAACAAAAGCAG
Long Flanking Sequence:
CATTAATGAGCAGCTGTGCCTAATAAAGCGGCCAGTGAGATTAATATTTAGGGTCAATTTCACAGAGTCTGTAAAGCTGGCTTAATTAGAGCAGTGTTTCCCAACCCTGTTTCCGAAGGCACATCAACAGTACACATTTTCAACCTCTCTCTAATCAAACACTCCTGAATCAACTCATCAGAACATTAGAAGAGACTCCAAAACCTGAAGTTATCAGGTCAGATAAGAGAGACTCCAAAATATGTTGCTGTGCATCTAAGAACAGGGTTGGGAAACACTAAATTAGAGGATTGAAAGTGGGAATCCACAAGAATGATTTTAGCATTTATCACAATGATCCCTTGTCTCTGATGTGCAGATCAGCTATTACCATCTTCCCCCAGAAGACAGATGGGAAGCATGACTTCCGGGTGTGGAACAGCCAGCTGATCCGCTACGCAGGCTACAAGCAGCCCGATGGATCAATTCTAGGAGATCCAGCTTCTGTAGAGCTTACAGAG[G/A]TGAGATTGATGTCGTTTTGATTGTTAGGCTCACAGACACAACAAAAGCAGCCACCAGACATTGATTGACGCATGTTACCTGTTCGCACAAAATTGAAGTGTCAAAGTGATTCATAAAAGACGTTTTTTGAGATGTCAGGGCTATTTCTTGGCAGCATTGAGACTGTGTTAGTTATATAAAGCTTTTTAAAGGGATAGTTCTCACAAATATTAAAAATATATCAACATGGACTCATCATTAAGCGATTCTAAGCCTGTGAAACCTTTTGAAGAGAAAAGAAGATATTATGAAGAAAGCTGGAAAACAATAACCAGTGACTGTTTCTCAATTACAAGAATGCAGAGAATTACGGTGGTCGGGAAGTGCAAAACAACCTTAAAAGTGTACCAATACCAATAAAGTGTACCTTTAGTACTAGAGCTGAGAACCTACACTGGTCTTACGGTTCAGTTACGATTATCATGCCATCAATTTAGATCAATTCGATATCTCGGTGCATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20353
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000099810 | Essential Splice Site | 709 | 1431 | 11 | 28 |
| ENSDART00000099822 | Essential Splice Site | 709 | 1431 | 11 | 28 |
| ENSDART00000125435 | Essential Splice Site | 709 | 1431 | 11 | 28 |
Genomic Location (Zv9):
Chromosome 5 (position 13234460)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 11645742 |
| GRCz11 | 5 | 12145959 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCACCAGGAAATGCTCAACTATCGCCTCACACCATCTTTTGAGTACCAG[G/A]TAAGGCTCTTGTCTATTTTAGAATGAAGTAGTATTGACTTTTAATTATGA
Long Flanking Sequence:
GCCATTAAGTCTAACTTTGACTTCGATTTCTAAAAGATCATTGCATTGTTTTAAGCATGAACATACTTTTTTAAATCTTAATTTTTTAAATGTTTTTTTTTTTTTAAACAAGATTTAATTTTTACCTAGGAAGGTTTTTATAATTGCACTGGAAAGAAGTTTTTTTTTTTTTTTTTTTTTTTGTGAGAGACAATGCTGTAACAGTAACAGCTGTAATAATGTAACAGTAGTTTTGGATTGCAGAGCTGTTTGTTTTTCCAGCCAGGATCTAAGTAGTTCCTATCTTTCTCATTTGCCGTTTGCAGATGTCAAAGGTTACCATAGTAGACCATCACTCGGCCACTGAGTCCTTCATGAAGCACATGGAGAATGAGTACCGAGTGAGAGGAGGCTGTCCGGGAGACTGGGTTTGGATAGTGCCACCCATGTCCGGTAGCATCACACCTGTATTCCACCAGGAAATGCTCAACTATCGCCTCACACCATCTTTTGAGTACCAG[G/A]TAAGGCTCTTGTCTATTTTAGAATGAAGTAGTATTGACTTTTAATTATGAGTGCAATTATACTTGCACATTTTGTGCCGAATGTATCATCCGTGTCATGTTTCTGAGGCATTTAAGGCTTTCATTTTAACTGGCAAGTACATGAAGCTTAAAGTAAGTGTGAACTATATATATATATATATATATATATATATATATATATATATATATATATATACACACACACACATACACACAGTTGAAGTCAGAAATATTAGCCCACCATCAAATTATTTGTTTATTTTTTTAATTTTTTCCTAATGATGTTTAACAGCAAGGGAATTTTCACAGTATGTCTGATAATATTTTTTCTTCTGGAAAAAGTCTTATTTGTTTTATTTCAGCTTCAACAAAAGTTTTTTTTTTTTTTTTTTTAAGATTTTAAACAACATTTTAAGATTAATATTTTTAAAGCAATTTTTTCCATAATCTACAGAACAAACCATCATTATACAATAACTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa14542
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000099810 | Essential Splice Site | 709 | 1431 | 11 | 28 |
| ENSDART00000099822 | Essential Splice Site | 709 | 1431 | 11 | 28 |
| ENSDART00000125435 | Essential Splice Site | 709 | 1431 | 11 | 28 |
Genomic Location (Zv9):
Chromosome 5 (position 13234459)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 11645741 |
| GRCz11 | 5 | 12145958 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCACCAGGAAATGCTCAACTATCGCCTCACACCATCTTTTGAGTACCAGG[T/C]AAGGCTCTTGTSTATTTTAGAATGAAGTAGTWWTGACTTTTAATTATGAG
Long Flanking Sequence:
CCATTAAGTCTAACTTTGACTTCGATTTCTAAAAGATCATTGCATTGTTTTAAGCATGAACATACTTTTTTAAATCTTAATTTTTTAAATGTTTTTTTTTTTTTAAACAAGATTTAATTTTTACCTAGGAAGGTTTTTATAATTGCACTGGAAAGAAGTTTTTTTTTTTTTTTTTTTTTTTGTGAGAGACAATGCTGTAACAGTAACAGCTGTAATAATGTAACAGTAGTTTTGGATTGCAGAGCTGTTTGTTTTTCCAGCCAGGATCTAAGTAGTTCCTATCTTTCTCATTTGCCGTTTGCAGATGTCAAAGGTTACCATAGTAGACCATCACTCGGCCACTGAGTCCTTCATGAAGCACATGGAGAATGAGTACCGAGTGAGAGGAGGCTGTCCGGGAGACTGGGTTTGGATAGTGCCACCCATGTCCGGTAGCATCACACCTGTATTCCACCAGGAAATGCTCAACTATCGCCTCACACCATCTTTTGAGTACCAGG[T/C]AAGGCTCTTGTCTATTTTAGAATGAAGTAGTATTGACTTTTAATTATGAGTGCAATTATACTTGCACATTTTGTGCCGAATGTATCATCCGTGTCATGTTTCTGAGGCATTTAAGGCTTTCATTTTAACTGGCAAGTACATGAAGCTTAAAGTAAGTGTGAACTATATATATATATATATATATATATATATATATATATATATATATATATATACACACACACACATACACACAGTTGAAGTCAGAAATATTAGCCCACCATCAAATTATTTGTTTATTTTTTTAATTTTTTCCTAATGATGTTTAACAGCAAGGGAATTTTCACAGTATGTCTGATAATATTTTTTCTTCTGGAAAAAGTCTTATTTGTTTTATTTCAGCTTCAACAAAAGTTTTTTTTTTTTTTTTTTTAAGATTTTAAACAACATTTTAAGATTAATATTTTTAAAGCAATTTTTTCCATAATCTACAGAACAAACCATCATTATACAATAACTTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa12337
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000099810 | Nonsense | 749 | 1431 | 13 | 28 |
| ENSDART00000099822 | Nonsense | 749 | 1431 | 13 | 28 |
| ENSDART00000125435 | Nonsense | 749 | 1431 | 13 | 28 |
Genomic Location (Zv9):
Chromosome 5 (position 13229195)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 11640476 |
| GRCz11 | 5 | 12140693 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TACTATGTATGATTTGCAGGGCTGTRAAGTTCTCCGCCAAACTCATGGGA[C/T]AAGCCATGGCCAAGAGAGTCAAAGCCACCATCTTATTCGCCACAGAAACR
Long Flanking Sequence:
CTAATGCTGGTGTGTGGTGAGCTATCATCGTTGTCCTGTGGCTGCCATCCCATCATCTAAGTAGATGCTACACACTGGTGGTGGTGTGGAGAGACCTCCCTTATGATTGTGAAGTGCTTTGGGTGTACGGCCATACACAATAAATGCGCTATATAAATACACATTACATTACATTACGAAAAACAAAATAATGGTTGCAGCTACCAGTTTATGTGGACTTTAAGCTGAATAATGAAACTTTTTTTAACTGTATTAAACTTGTTACATAACTGCTCAACTCTGTTATTGAACAGAACTGAATCAACACCAATCCAACTTGAGCTAAATAATGACTGTTGTCATAATTTATAGTTTCTTGTTGTTTGAGTTTATCACTGCTTTCATTTAGCCTGTTATTATAAAAGTCGTATTAAATACTTGGCGTAAATATGACTTGACATATATGTCTGTTACTATGTATGATTTGCAGGGCTGTAAAGTTCTCCGCCAAACTCATGGGA[C/T]AAGCCATGGCCAAGAGAGTCAAAGCCACCATCTTATTCGCCACAGAAACGGGGAAATCGCAGGACTATGCAAAAACGCTCTGTGAGATTTTCAAGCACGCATTTGATGCCAAGGTAAGAACGACAGGCTTATTGAAACACAATAGATTGACATCTGCGCTCAATTCTTGAAGCCCTTCCCAACTTCCATTCATCCCACATGAATGCCACCAGTGGATTTACACGTACGCATTGATGTAAGCAAAGCATATTAGTTTAAGATACCCTCTTTTTTCTCAAGCAAAATCTGTCTTCCAGTTTACAGAATAAAAGCCATTTTCACATCAAAGCGCGCAATGCTAAAGCTTACACAAATGTGCCTTTTCCCACAATTTCAGTCATTTCAGTGGCATAAAATGACAAGAATTGACGCATTTGTGCATTGAGCTGTAGGTTAAGATACCATCAAGTTACGCTTGAAGCTACATGACGTATGAAACAAGCGTATTGACTCGATCAAGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa11824
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000099810 | Nonsense | 1285 | 1431 | 25 | 28 |
| ENSDART00000099822 | Nonsense | 1285 | 1431 | 25 | 28 |
| ENSDART00000125435 | Nonsense | 1285 | 1431 | 25 | 28 |
Genomic Location (Zv9):
Chromosome 5 (position 13196626)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 11608029 |
| GRCz11 | 5 | 12108246 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTATTTCAATCAGGAATCAAGGCTTGCCCCATGATCTTGGTGTTTGGTTG[T/A]CGGCAGTCCCAGATTGACCACATTTACAAGGAACAGACCATCCAAGCCAA
Long Flanking Sequence:
TATCTTTTTAGTGGTATTTTTTTTTTTTTATTTATTGCACTTTTGTTATTTTTGCCACCCTTTTGTTGTATAAAATTAAGCAAAATGTTATATTTGTTTAATAATGCAATGATTTTTTTTATTTGAGGTTATTTATTATTTATTATTTCTTTAATGTATTTTTTGCCACATGTTTGTAGTATAAAAGTAAGCAAAATGTTATATTTGTTTATTAATATAATTTAACATAAGTTGTCAACAAAATGCAGCTTATTAAATGTATTAATGTACATCGACATTAACATAAGTAAATTAAATGTACTTTTCAAAATTTATGAAGTTGTATATTTATATTACAATTATATTATATTTTCTGATTAATTCTTTATTGCACAACTGAATATATTGTATATATAATGTGAATATATTTGCACAGACATACCTTGTCAATTTGCATTAAAACATGACAACTTATTTCAATCAGGAATCAAGGCTTGCCCCATGATCTTGGTGTTTGGTTG[T/A]CGGCAGTCCCAGATTGACCACATTTACAAGGAACAGACCATCCAAGCCAAGAACAAGGAAGTGTTTAAAGAGCTTTACACGGCATACTCTAGAGAGCCCGGAAGACCAAAGGTTAGGACTTTATTAATTGTTAGATTTTTTAATTTAAATGTATACATGTATTACTAAGAAGAAAATAGAGAAAATGTCAGACAGGTGGGCCTTCAAAAAAAATGTATCTGAAAATGAATTAGGAAGTGAAAAAAGTCTTAGATTGTGAACCCTGTAAGAATAAGAAATTTGTCGTTGCACCATGTGCTTTATACTCTTTTATCCTTTTTGTCATCTAAATAACAGAATTTTTGTAATAAACATTTAACAACTTTCTTTCAGTGTTTGTTATGGATGTCTAATGGCTTGTTTGGTGTTTTTTTTTTTTTTTCTCTCTCAGAAATACGTCCAGGATGTGCTCCGCGAGCAGCTATCTGAAACTGTGTACAAATGTCTAAGAGAAGAAGGAG
Associated Phenotype:
Not determined