Busch Lab

ZMP

si:dkey-103j14.2

Ensembl ID:
ENSDARG00000079230
ZFIN ID:
ZDB-GENE-090313-168
Description:
Novel protein similar to vertebrate sorbin and SH3 domain containing family [Source:UniProtKB/TrEMBL
Human Orthologue:
SORBS1
Human Description:
sorbin and SH3 domain containing 1 [Source:HGNC Symbol;Acc:14565]
Mouse Orthologue:
Sorbs1
Mouse Description:
sorbin and SH3 domain containing 1 Gene [Source:MGI Symbol;Acc:MGI:700014]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa1288 Nonsense F2 line generated Not yet available
sa17635 Nonsense Available for shipment Available now
sa11347 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa1288
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004908 Nonsense 369 580 19 25
ENSDART00000043870 Nonsense 290 501 12 18
ENSDART00000135678 None None 136 None 6
ENSDART00000137040 Nonsense 527 659 19 21
ENSDART00000138732 None None 151 None 5

The following transcripts of ENSDARG00000079230 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 23435281)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 23080941
GRCz11 13 23211391
KASP Assay ID:
554-1203.1 (used for ordering genotyping assays)
KASP Sequence:
TCTTTTATTAGGGAACTTCCATTTCAGAAGGGAGATATAGTATACATCTA[T/A]CGGCAGGTCGATCAGAACTGGTTTGAAGGAGAGCATCATGGGAGAGTTGG
Long Flanking Sequence:
GACGGCTGAAGCGAGAGCAGGAAGAGGCAGATACAGCTGCTCGGAGACACGCTGGGCTGGTTGTGACTCATCAACAGTTCATTACTAATGACCGTTTTGGCGACCTGCTGGTTATTAATGAGAAGGAGAAGAGAAAAACCATAGAGGTGATGAATGTTCTCTCTTGTTATGCTTCAAATGCTCATGCTGGATGATGACAGTCTTTATATACGGCACAGACAGTTGCTCTGCAAAACAGATGCAGTGCTACAGAAATGATGCTAATAGCCTCTTTTGGTCTACAGAGGACTCCTGCTCTGGCACGATTTGACTTCAGAGCAGAAAGTTTAAAGTAAGCATGTTTCTCAATTCAGATCTGAGAATGCTAATAAGATCCTCTTGCATCTTTGTTATTGTAACAGCAAATCAAATTTGAAATACCACACTACTGATTGAATTACATTTTGCTGCTCTTTTATTAGGGAACTTCCATTTCAGAAGGGAGATATAGTATACATCTA[T/A]CGGCAGGTCGATCAGAACTGGTTTGAAGGAGAGCATCATGGGAGAGTTGGGATTTTTCCACGGAGTTATGTTGAGGTACTTTATATCCTTAACTAATATGTTTTGTATGCTTTCAGATTTGCAGTACCCTTATGTAAAGCAATACTTTTATAATAATAGTATAATATAAATTAAAAATTATATATATTAATAGTCAAATGCTTTACTACAAATATTTTTTGTAGTTAACTACCATACAAATTAAGAAAGTACAGGGTTAGGTTTTACAACACTAACCATAGTTTAACCATAAGTTAATAAGGCTGTGTGTCATACAAATTGTGATCAATACACCAAAAAATTGTCACTACACTTTTAATATAATATTGTATTACTATTTTTAATCATAGTCAATATACTATGTTATTTTATTTCTTCAGCTGGTGCCCCCAACAGAAAAAGCTCAGCCCAAAAAGTGTGCTCCGGTCCAGGTGTTGGAATATGGAGAGGCTCTTGCTCGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17635
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004908 Nonsense 392 580 19 25
ENSDART00000043870 Nonsense 313 501 12 18
ENSDART00000135678 None None 136 None 6
ENSDART00000137040 Nonsense 550 659 19 21
ENSDART00000138732 None None 151 None 5

The following transcripts of ENSDARG00000079230 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 23435350)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 23081010
GRCz11 13 23211460
KASP Assay ID:
2260-6361.1 (used for ordering genotyping assays)
KASP Sequence:
TGGTTTGAAGGAGAGCAWCATGGGAGAGTTGGGATTTTTCCACGKAGTTA[T/A]GTTGAGGTACTTTATATCYTTAACTAAYATGTTTTGTATGCTTTCAGATT
Long Flanking Sequence:
ATCAACAGTTCATTACTAATGACCGTTTTGGCGACCTGCTGGTTATTAATGAGAAGGAGAAGAGAAAAACCATAGAGGTGATGAATGTTCTCTCTTGTTATGCTTCAAATGCTCATGCTGGATGATGACAGTCTTTATATACGGCACAGACAGTTGCTCTGCAAAACAGATGCAGTGCTACAGAAATGATGCTAATAGCCTCTTTTGGTCTACAGAGGACTCCTGCTCTGGCACGATTTGACTTCAGAGCAGAAAGTTTAAAGTAAGCATGTTTCTCAATTCAGATCTGAGAATGCTAATAAGATCCTCTTGCATCTTTGTTATTGTAACAGCAAATCAAATTTGAAATACCACACTACTGATTGAATTACATTTTGCTGCTCTTTTATTAGGGAACTTCCATTTCAGAAGGGAGATATAGTATACATCTATCGGCAGGTCGATCAGAACTGGTTTGAAGGAGAGCATCATGGGAGAGTTGGGATTTTTCCACGGAGTTA[T/A]GTTGAGGTACTTTATATCCTTAACTAATATGTTTTGTATGCTTTCAGATTTGCAGTACCCTTATGTAAAGCAATACTTTTATAATAATAGTATAATATAAATTAAAAATTATATATATTAATAGTCAAATGCTTTACTACAAATATTTTTTGTAGTTAACTACCATACAAATTAAGAAAGTACAGGGTTAGGTTTTACAACACTAACCATAGTTTAACCATAAGTTAATAAGGCTGTGTGTCATACAAATTGTGATCAATACACCAAAAAATTGTCACTACACTTTTAATATAATATTGTATTACTATTTTTAATCATAGTCAATATACTATGTTATTTTATTTCTTCAGCTGGTGCCCCCAACAGAAAAAGCTCAGCCCAAAAAGTGTGCTCCGGTCCAGGTGTTGGAATATGGAGAGGCTCTTGCTCGTTTCAATTTCACCGGCGACACTGCTGTTGAAATGTCTTTTAGAAAGGTATTAAACTTTTTCAACAATTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11347
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004908 Nonsense 556 580 24 25
ENSDART00000043870 Nonsense 477 501 17 18
ENSDART00000135678 None None 136 None 6
ENSDART00000137040 None None 659 None 21
ENSDART00000138732 Nonsense 127 151 4 5

The following transcripts of ENSDARG00000079230 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 23444542)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 23090202
GRCz11 13 23220652
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGCAGGAAGGAGACCTGGTCAAYGTCATGGAGAAATGTGATGATGGCTG[G/A]TTTGTGGGTATGTGTCATTTATTATTATATTGATTCTCCATGAAAAGTCA
Long Flanking Sequence:
TGGAGCTAAATAGTGCAGTAAGTTTTTTTTTTTTTTTTTTTTTTTTACCCAGACATTTAAAAAGAACTCATTTTAGTGCAGTTATTACAATACAGTGAAATCGTGATATTTTTATCCAAAGTTATACTCTTGGTATCTTATACCAGCCTATGCCTATTCATTAGCTACACATGAAATATTTTTTCAGTGTATCTATGCAGTCAGATTTGTTTGTGATCAAACTGGAAAGCCAACCTACAGTGCAGTGCTTTAAATTTAAGCTAATCAACTTTTAGTGTAAAATGAACTGAAAGACTAAATATTCTTAACAGTTTTACATTTAGTTAGTGCAGTTTTATTTGTGCAGTAGATTCCCCCAGGCTCCAATTCCATGTCTGATATTGTGCTGTTTTCTGCTGTAGATTTCAGGCTCTGTACAATTACGTGCCTCAGAATGATGATGAGCTGGAGCTGCAGGAAGGAGACCTGGTCAACGTCATGGAGAAATGTGATGATGGCTG[G/A]TTTGTGGGTATGTGTCATTTATTATTATATTGATTCTCCATGAAAAGTCATCTCTCAAAACTACAACACTCCTACAGTAAATCAATTCTCGACCACTGCTATTGAGTTTTGTTTTACTGGAGATGGGTTATTGTTGATAACTAAAACTGAAGCAAAATCGTAAAACTAAAACCACTTTCATTTCTTGAATAAACATTAACAAAAAAAAAAGAAAAAAAAAGAAAGGAAAATAAAAAGTAAATATATAGATATTGTTTTAGCTTCTTGCCGCGTCACATGCTTGCACTGTAATATTACTACATAGTGCTAATTCATAATCATGTTAACAACATGCTAATTCATACTAAAATCATTCTAACAGCATGCTAATTCATACCAGAAACTGCCAACCTGATTTCACCTAGTAGAACATGCTCCGGGATTAAGATCTATGTTCATCCTGGAACAACATTCCAATTAACCAATCAGAGTTAAAGGATACATTTACAGTTTGTGTTAAG
Associated Phenotype:
Not determined