ZMP
ednra
Ensembl ID:
ZFIN ID:
Description:
endothelin-1 receptor [Source:RefSeq peptide;Acc:NP_001092915]
Human Orthologue:
EDNRA
Human Description:
endothelin receptor type A [Source:HGNC Symbol;Acc:3179]
Mouse Orthologue:
Ednra
Mouse Description:
endothelin receptor type A Gene [Source:MGI Symbol;Acc:MGI:105923]
Alleles
There are 7 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa19531 | Essential Splice Site | Available for shipment | Available now |
| sa1973 | Nonsense | F2 line generated | Not yet available |
| sa11317 | Nonsense | Available for shipment | Available now |
| sa13839 | Nonsense | Available for shipment | Available now |
| sa19532 | Nonsense | Available for shipment | Available now |
| sa32714 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa19531
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010632 | Essential Splice Site | None | 422 | 1 | 8 |
| ENSDART00000128557 | None | None | 24 | None | 2 |
The following transcripts of ENSDARG00000011876 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 36373894)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 35933752 |
| GRCz11 | 1 | 36665779 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGACTGACTGACTGACGGGATCCTGGGGAAGGCAGACATTTAAGGAGCG[G/A]TAGGTGAAAAACCAGGAGACATTTATAATTCATAAGTGTAGCAGTTTACG
Long Flanking Sequence:
GAAGGTTACGACACGGCGGCAGGGGTTCTGTCAGGGCAAGAGAAGGAAAACGGCAAAGATGGCAAACCTCAGGAGAGGACTGGTAATTCCTCCTGATGCTTCCCGAGCTCAGGCTGACTGTCGACAGTCAGGCAGGCTGTGCCTCAGCAAGCGCTGGTGTTTCCTTTGGGGCCCCCCTCCCGGCCGAGGGGGGAGGTGGAGAATTACAATCCCACCCCGTCAAAGTGCTCTCTCTTAAACACTCACGTACACACAAGTACACACACACACATACAGCAACTCTCCACAGGAAAAGCTGGAGACAGAATGCGCAGCCCCTTCACAGCAGCTTTGGTGCGTCGTGGCGTCCAAATGGGATTCTGCTAGACTTTGATAGTTGGTTAATTACTCATATGATACCACACAGATGTCTGGGGGGCTCTAGCCGAATATTCGTCTCTCACTAACTCACTGACTGACTGACTGACGGGATCCTGGGGAAGGCAGACATTTAAGGAGCG[G/A]TAGGTGAAAAACCAGGAGACATTTATAATTCATAAGTGTAGCAGTTTACGTGCCGTTAAGGATCCCTTTAGTGCCTAGCTGATGCTAAACTGAGATGCTACTTGAAGGGCTGTCTACTAAATAGTTCCTTGTGTACCAGGTGGTGGCAGGGACTTTGAACAGGAAACACATCTTGGCTCTGAAGTGTTCCTTTGCTGTCAAGATAATGAAAGGGGGGTTCAGATGATTTCAAACAAGATGAGAGTTGATTAACTTTTCTCACTTGTGATTCTTACGCGGGGCTTAAACAGGCTATATTTGTTATTTGAGGATTCAATTATTGAACTTTTGTTTCGGGGGGAAGAGTTTCAGATCATTCTTTGTGAGTAAAAAGTAGTTTTTTTAATATGGATTTGATGTTTAATTCTCTTTTTAATGTGATAAAATCTATATGGCTGCTATATTCTAAAAAACATGTGACAACATCTGTTACACTCTTAAAAATGTTCTGAACCAGGATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa1973
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010632 | Nonsense | 20 | 422 | 2 | 8 |
| ENSDART00000128557 | Nonsense | 20 | 24 | 2 | 2 |
The following transcripts of ENSDARG00000011876 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 36382796)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 35942654 |
| GRCz11 | 1 | 36674681 |
KASP Assay ID:
554-2675.1 (used for ordering genotyping assays)
KASP Sequence:
TACGACGCTACAATTGTTTCTGCTAATGGCCGTTCTGGCCACTGGTGGAT[T/A]ATGTCTGATAAAYGGCACAGAGGAAGCCCAGGATGCTTTATATCCAAACT
Long Flanking Sequence:
AACCCAGCTCGACCGTCTGCCACCGCGAAGACCCACTCTGGACCGGGAGACACACTCGTTCGCTCTGAAGTGCTGATCAGCAAGAGGAACCCTCATCGACTCACTCAGAAAGGATCTGAAGCGAAAAGGATGGCGTCTGCTGGCTTCAGGTGTGCTTATATGCTGAGATGATTGCAGATGTCGCACACCTGCGCAAGCTTACGCTGCCAATTAATTTCATTCATTGGCCCGTTCAATACTCTCCAGATAAGCGGCTTCTGATCCGAATCCTCCCATTCATGGCACTGAAGTTCCCCAACCGAAGGGGAACTCTGACTTGCTTTACAACACAGCATGTTTTTGATGTCTCTCCTGTTGTTTCTTATCCCGCAGCTGTGCTAAATAACCCTAATCAGGCTCTTATCACCTCATCTGGAAATCAAAGAGCGGCCAGTGTTCTGCAATGGCCATTACGACGCTACAATTGTTTCTGCTAATGGCCGTTCTGGCCACTGGTGGAT[T/A]ATGTCTGATAAATGGCACAGAGGAAGCCCAGGATGCTTTATATCCAAACTCTACTACCTCCAAAACCAACGTACACAAGGGTTTCCAGCCCCCCACAAAAAAAGACGCTTCGGTTTTCAATATGAAGCATCCACCCTGTAGGGATCCCACTTCCATCAAGCTTTATTTTAAGTATATCAACACAATCATTTCCTGCATCGTGTTTGTGGTGGGAATAGTGGGTAATGCCACTTTATTGAAGATTATTTACCAGAATAAGTGTATGAGGAACGGACCCAATGCCCTCATCGCCAGTCTGGCTCTTGGAGACCTCATTTACATCACTATAGACATCCCTATAAATGTCTACAAGGTAGGCACAACTTTATTTCCAATACAAATGATATAGGGATGGTGATACAGACTTAAAAATATATCACATTATTTTCTTGCGATAATAATTTTAATCATGATATAATTCCCAAATACCCATTATATTTTCAAAACATTTGATCAATTAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa11317
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010632 | Nonsense | 163 | 422 | 3 | 8 |
| ENSDART00000128557 | None | None | 24 | None | 2 |
The following transcripts of ENSDARG00000011876 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 36391010)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 35950868 |
| GRCz11 | 1 | 36682895 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATGACAGCTCCTTTGGWCTCTTCCTGTGCAAACTTGTGCCATTCCTCCAR[A/T]AAGCGTCTGTTGGGATTACAGTGCTCAATCWATGTGCTTTGAGTGTGGAC
Long Flanking Sequence:
ATTAGTTTTACCATTCCAATGTTATATGTACATTTTTTTAGGTGTTTTATTTTGTTGGTTTTGTTTTTTATGATAACATAGTTTCCAAAAGCATTTTATTTATTTAGCTGGATATCTTTTACAGCTCCAAAATATTTTAAATGTTTCCCAAAATAAAACTGTGTTCAAAGCTTGTAAAAAAAGGGGGGGAAAAGTTTTTGTTTCTTACTCAAAAAACTTATTTTAGAGCAGTGATCACAATACTGTTATACTGTAAAATCGTGATATTATTATCCAAGGTTATCATATAATCAGAATCTTATACCGACCCATGCCTAGATTCAAATAGTGGTTTATTAATTCTTCATCCAAACCTCCATGACTTAACTGTAGCATATTATTGTGTTTTTCAAGTTTTCATTCATGTCTTTGTATTTTCTTTGCAGCTGCTGGTCACAAAGTGGCCATTTGATGACAGCTCCTTTGGACTCTTCCTGTGCAAACTTGTGCCATTCCTCCAG[A/T]AAGCGTCTGTTGGGATTACAGTGCTCAATCTATGTGCTTTGAGTGTGGACAGGTAAATGACAGCTTCAGCTTTTTCTTATTAAAGCATGCATATGTGGTTCTAAAGTGCTGGATAATTATGTGCATAAACCAAAACACTGGTTCTTGATGCACATATTTCAATTCTGAAACAGGTGTGTTTAAAGAGGGACACCTGAAGTGTTGAGGGGAACACAGGAACTAACACCACATTTATTTTAAAAATAAAAAAAATAAAAAAAAACAATGCATGCTGTTTATTTTTTTGAACACGTCACCATTTTTCTCAAAAATCATATTCTAATGATGCTGTTGACTTGAAATTTTCCCCAGATGTAGGTAAAAACAAACAAAAAAAATCCATATATTCAAAGAAACAAATCAAATTAGTTTACGAATTAAGTTATGCATAATGAAATGAATGCAGGAAAACGTATTGAACACATGAAGAAAGGAAGGTGTAGAAAGGCAGTGAAAGTCCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa13839
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010632 | Nonsense | 189 | 422 | 4 | 8 |
| ENSDART00000128557 | None | None | 24 | None | 2 |
The following transcripts of ENSDARG00000011876 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 36399013)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 35958871 |
| GRCz11 | 1 | 36690898 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTATGTTTTGMATGTCTCAATCAGGTACAGGGCTGTAGYCTCCTGGAGC[A/T]GAGTGCAGGGGGTCGGCGTTCCTCTTCTTACTGCCATCGAGATCTTCTCC
Long Flanking Sequence:
TCTGTACGTGTGCTTGTGTGTAAATGCTCGCACTACTCTGGCTCTAATTGACAAACAATGGAAATGTACTCTATCTAAGCCAATCATCTTGTTCTCGGTTACACCATGTTCACAGACACACCAATCATCATCACTGGCCCTGAACACACACACACACCCCAGAGAAACAGAGGTCCTATTGCTGAGAGAGACACTGCTTGCATGAAAACTGCTTCAGTGATCTTAGTTATGGTAACATAATGGTATTGTCATTGTAACGGGGAAACAGCAATTAATTTGATTATTTGTTTCTTTAAAAAGTATCACCATAAACAACGCCCTTTATTTACACCGCTGTTATTCCCATCACTGGTTGTCTCCAGCACTAAAGAAAAGTTAGAAACAACACCCTGTAAACAATATGACTCTGGTCTGAACTGATCAAACAGATCAACAATGTTTGGTCATGGTTGTATGTTTTGAATGTCTCAATCAGGTACAGGGCTGTAGCCTCCTGGAGC[A/T]GAGTGCAGGGGGTCGGCGTTCCTCTTCTTACTGCCATCGAGATCTTCTCCATCTGGGTGCTGTCCATTATTTTGGCAGTACCTGAGGCAATGGTCTTCAACATGATCACCTTCACCTACAATAATCAAACCATCCGCACATGCATGCTCAAGCCTGAAACTGACTTCATGAATGTAGGTTTCAACCAGATGGTCTTTTCCTTTCCTTCCCAAAACACTCTTAAACACTTTCCAATAAACGGAGCATTTGTGCAGCATTTCTGTGATCTTCTGCAACTTTAATCCTGAAAACAATAGTGGGATAAAAGTAAAACCTTTGAGTTTTCTTCATCATGCATCATGTGGGTGATATCTAGAGATTTCGTTTGCTTTTGTTTGGGTCCAAAGAAGTAAATTGATAGCAGACCTTGAGTGCAATTACAAGCTGATGGATCTTCCTCAAGGAGAGCCATATGTGCAGATTAGAAACATTCACTCCGCCATTAATCACAAAAACAACAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa19532
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010632 | Nonsense | 283 | 422 | 5 | 8 |
| ENSDART00000128557 | None | None | 24 | None | 2 |
The following transcripts of ENSDARG00000011876 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 36401303)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 35961161 |
| GRCz11 | 1 | 36693188 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTGCACGGCTATTTTCTACACACTCATGACCTGTGAAATGCTGCATCAC[A/T]GAGATGGAAGCCTTCGCATCGCCCTCAGTGAACACCTTAAGCAGGTAAAG
Long Flanking Sequence:
AGTCAGACTTTACTGTCCTAATGAAATAGTTAAAAATCAAGACATGATCATATTTTATTTTGGTAAAATAAGTGTAATCTTGAGGCCTTTGCCTTTCATATAAACCACTTCTGATACCAAATGATTAACTAGAAGTCAAGTTATTATTTATTGTTTCTAAAACGTAGATAGGCGACAATACTTTTGTCTTGAACAGAATTTTTCACAGCTCAATTTTTGCTATTTTTACTGACAGCTAGCTACCTGTCAAATTCACATTTACTAACTATTTATTGGGATAACTCATTTTACATGATTTCTCAGTGTCTGTAAACACTGCATGATATATTTTTGTTGTTTACCATAAATATACAGCATAATGTTTCCTAAAAATATTTTTTTTCTGCACTCAGTTCTATGTGTACTGGAAAGATTGGTGGTTATTTGGCTTCTACTTCTGTGTGCCCCTGGCCTGCACGGCTATTTTCTACACACTCATGACCTGTGAAATGCTGCATCAC[A/T]GAGATGGAAGCCTTCGCATCGCCCTCAGTGAACACCTTAAGCAGGTAAAGAAAAGTCTGATTGTCATAAAAAGCAAGGTGTTACTTACAGAACAGCAAAGGTCTTTATTTTGTATATAAACAATTATCTCACAGTTTCTCACTTCCACCAATAAGAATCAACGTTTTTATAACATCACTCTGCACTTAAAGGGGACCTATCATGCCCCTTTATTTTATATAATAAATGAAGCCTCAGGTGTCCCTAGAGTGTGTATATGTGTGTATTGCTTTCAGGCTTTGATCCAAAGTGTGCCATTTTGGTTACTGTCATAATAGTTTTGCATAATAGTTACTAATAAGCTTCTCGATAGTGATGCAGTAAACGGTAGTGCTGACACTGTGCTGATCTGAATTCCTGTACGTTCATCAGTCGTATAACAAGTCAACGTTGAGCACAGCATGTGCTGGATTTATTTAGATGACAATGAATAACGTAAAGCAGAGAGATTGATAGATTGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa32714
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010632 | Nonsense | 372 | 422 | 7 | 8 |
| ENSDART00000128557 | None | None | 24 | None | 2 |
The following transcripts of ENSDARG00000011876 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 36406153)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 35966011 |
| GRCz11 | 1 | 36698038 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGACTGTGAACTCTTGCATCAACCCCATCATTCTCTACTTTGTCAGCAAG[A/T]AGTTCAAGAATTGCTTTAAGGTGAGTTGTTTATTCCTTCATTAAAAAAAC
Long Flanking Sequence:
ATTACTTTAATTTAAAAGGAGTAAATTCACAGTACTAAGATAAGTTTTTTAACTCATTGTTTGCTGCAATCGGTTTCCTCAAACGGTTTGAGTTGTCTTAGCTTATTGGGTTTTACAGTACGCAGTTGGTTTGAGTTCCCTTCATTTATTGGGTTTTACTGTGCTCAAATTGCTTCATTTACTCAAATGGATTAAGTTCACAGTACTCATTGGGATTAGTTTCTGAACTTAAATTGTTTGTTGCAATCAGTTTCCTCAAATGGTTTGAATTACCCTAACTTTTTGGGTTTTACAGTGTACATTTTAATTAATCAAAAAAAAAAATATATATATATATTCTTTAAAATTTTACAAGTACAAGACCCTGATGTCCTATAGATTAATATTTTATGACTTGTCTTAAAATTTACAGCTTCCTGTTGATCATGGATTATTTTGGTATCAACTTGGCGACTGTGAACTCTTGCATCAACCCCATCATTCTCTACTTTGTCAGCAAG[A/T]AGTTCAAGAATTGCTTTAAGGTGAGTTGTTTATTCCTTCATTAAAAAAACAGACTCACAACAAACTGTTACCAAATGTTTTCCTTGCGTCTTGGCAAAACCTGAAAACAGAGCATTCTATCAGCAAACTGTTTTTGATTTACTGTCCTGTGAGTCATTGACAGAGAGAGAGAAAGAGACGAAGAACGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGATTGAATTTTGTTTATTACCAAATAATTCCATAATTATTCAGACATTAAGCTCCTAAAAAGCATTAGAATTATCAAAAATTGAGCCTAAAGCTCCTTGAAAACACCAATTCAGATAGAGAAAGAGAAAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAGCTATGTCTGGTTCTGGTTGTCTTGCTAGTTTACTGAAAGTGATGCCAGACCCACAAAAGAGTGGTCTCATTTGAATAATGAGGACAATCCCAAAGATACAATGCAGCTC
Associated Phenotype:
Not determined