ZMP
melk
Ensembl ID:
ZFIN IDs:
Description:
maternal embryonic leucine zipper kinase [Source:RefSeq peptide;Acc:NP_996771]
Human Orthologue:
MELK
Human Description:
maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:16870]
Mouse Orthologue:
Melk
Mouse Description:
maternal embryonic leucine zipper kinase Gene [Source:MGI Symbol;Acc:MGI:106924]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa19483 | Nonsense | Available for shipment | Available now |
| sa11312 | Nonsense | Available for shipment | Available now |
| sa14613 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa19483
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000047728 | Nonsense | 130 | 676 | 5 | 18 |
| ENSDART00000125259 | Nonsense | 130 | 676 | 4 | 17 |
Genomic Location (Zv9):
Chromosome 1 (position 20714933)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 21187029 |
| GRCz11 | 1 | 21879966 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTTTCGCCAGATCATCTCTGCGTTGGCCTATGTTCATAGCCAAGGTTA[T/A]GCCCATCGAGACCTCAAACCTGTGAGTTTGTCTTTGAAAAAGGGTTGTCG
Long Flanking Sequence:
AAAAAGATCTTGGGGTTTGTTATTCATTTTAAATGCCTTTACCATGAATCACAACATTTGAATGAGTACCTTAATAATTACGAAGGAAGTTATTTCTGAATTTATTCCTGATATTGAGATTTAATTTACTTTTGAAATTCAGAATAGTGTCTTTCAAGTGTTTATGTTACTAGGATGATCTGCCCAGAGTAAAGATAGAGATTGAGGCAATGAAGAACCTCAGTCATCAACATGTATGTCGTCTCTACCATGTCATTGAGACCACAAGCAAAATCTACATGGTGCTTGAGGTATGCTTTGCTGAATGTGGTTCTGATGTTTAAGGAATACCTATTAATCTTCATATGTTTAACTGCATGTATCTTGTCAATCTATCAGTACTGTCCTGGAGGAGAACTCTTTGATTACATCATTGCTAAAGATCGGTTATCAGAGGAAGAGACCCGAGTGTTTTTTCGCCAGATCATCTCTGCGTTGGCCTATGTTCATAGCCAAGGTTA[T/A]GCCCATCGAGACCTCAAACCTGTGAGTTTGTCTTTGAAAAAGGGTTGTCGACTCTGAATTAAAAATTGCCTTCACTATCTAGACAGGTGCCGGTATTGTGAGTACTGCACTAAAATATATTCTTTTTAAATGTCTGGGTAAAAAACCAACAACCTTTTTCCACTTTGACCACAAAATATTTTATTTTGAGAAACATTTAAAATATTTTGGATCTGTAAACATGTCAGCCTAAATAATTCAAGTCAATCATTGATTTCTGCTGTTGTCATTTGTTTTAAATTTGTTGAAATTTGTTTCTGCTGTTGTCATTTGTTTCAAAAACAGATTTCTTTACCATTTAAAATGGAATCTTTGGATATCTTTTCTGCTGCAGATACTGTTCTCATAAAAAAATTGAAACGTAAATAAAAACAATCTTACACATACCTTAGGAATGGTATAGCAGAAAAATTTGGCGGTGTTAAAACCCTGAGTTTTCCAAACTGCAGTATACCTTAAAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa11312
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000047728 | Nonsense | 269 | 676 | 10 | 18 |
| ENSDART00000125259 | Nonsense | 269 | 676 | 9 | 17 |
Genomic Location (Zv9):
Chromosome 1 (position 20710545)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 21182641 |
| GRCz11 | 1 | 21875578 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGTTTGACAKTGAAACATTTGCTTGATCACCCATGGGTTATGAGGGGCTA[C/A]AGCACACCAGTGGAGTGGCACAGTAAATATCCAGTAAGATCAGCTCTATT
Long Flanking Sequence:
CATCGATTGCGTGTGTGTTTCAGGCTGATGTTTGGAGTATGGGTGTATTGCTTTATGCACTACTGTGTGGTTTTCTACCATTTGATGATGACAATTGTATGGTTCTCTATAGAAAAATCACAGTAAGTCTATTCATGCTGCATAACTTGTGAGTAGCATTTAAACACACATAAATACACATTTTGTTGATCTACACATTTCTTAGCTTACTGGAATAAAAAAAAAGTTGTCTTGTGTAAATGTGTGATCGTATGTCATATAAAATTGGCTTATGTTTTGACAGAGAGGCAAATACAGCAACCCACACTGGCTTTCGCCTTCTAGTATTCTGCTTCTAAACCAAATGATGCAGGTAGTGTGTATGGTTTGTGTGTGTTTTTGTGTGTGTTTGATGTGTTTTATAAAGCAATGACAGTTTATTTTGTTCTCCTGCAGGTGGACCCAAAGAGGCGTTTGACAGTGAAACATTTGCTTGATCACCCATGGGTTATGAGGGGCTA[C/A]AGCACACCAGTGGAGTGGCACAGTAAATATCCAGTAAGATCAGCTCTATTTACATGCTTATAGTCACATCATATGCTTCCATGACTCCAGTAGTGGAAGTGGGCTTTTGAGCCTAATGGCACAATATGTAAGATGACTTTCATCAAAATATGCAAACCATATTGAAGTATATACTTGTAAAATCTCAAATGCTTCAAGGAATATTTAATTCCAGATAAATAATTTTTACTTTTAACAATATATATTTTTATTTTAAATGTTACGCACTCGATGTCTGTTTGGTTAGTAGACTACACAGAGCAGCTTTATAACAGAACCCTTAAATGTTTGTATCGTAAAAAAACAGCGCTGCTTCTTTCCTATGGGATCATGACCAGAAGAACTGTCTGAGGTTAACTGTGGAATAATAAAAGCTGTGCTGCTTTTGTGTCTTATCAGCAATTGTTTCAGCGCACTCGTTTCAATTTGACAGCTTTCACCCTTACTCTGCAACATACTTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa14613
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000047728 | Nonsense | 298 | 676 | 11 | 18 |
| ENSDART00000125259 | Nonsense | 298 | 676 | 10 | 17 |
Genomic Location (Zv9):
Chromosome 1 (position 20709571)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 21181667 |
| GRCz11 | 1 | 21874604 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGGGTCATATAGATGAAGACTGCATCACAGAAATGGCGGTGACTTWCAAA[C/T]AGTCCAAACAACGAACTATCCAGCTTGTGTCTGAGGTAGAGGAATTTAAT
Long Flanking Sequence:
TTTCACCCTTACTCTGCAACATACTTCCACGATAATAAGTCTTGAATACTTTAGTTCATGCATGAACATGATTTCTCCAGTAGTACTTTAGAATGTAATATAGAGCACAAGTTCCATTATCTCACACCAAACAATGCCTTTGTTTGTTGTGAATATGTGGTGAAAATTACATGTTGTGCCTTCAAAAACTGTTATGATAATATAGTGGTTACTTAATAAATTCTATCTGCTTTAGTTGTTGTAATGAATCTGCATGTCTTCAGTATTTTAGGTCCAATAGATTTAATATAATATAGTCCTCCTTTTGAACAAAGATGATGCATTTATTTTTCAGCAGAGCTCATTGTTTCTTCATAGATGCACATTCATAATGTATTTTAATCATATCTTAGCTTAGCTTTCTTAGCTTGTGTGTTGTTCAATTAATTATAGCATGTGTTTCTTTTTAGTTGGGTCATATAGATGAAGACTGCATCACAGAAATGGCGGTGACTTTCAAA[C/T]AGTCCAAACAACGAACTATCCAGCTTGTGTCTGAGGTAGAGGAATTTAATATTATTGATGAATTCTAGTTTCCCAGTGATTAGTTGCGGCTGGAAGGGCATCCGCTGCGTGAAAGCATATGCTGGATAAGTTGGCGGTTCATTCCGCTGTGGCGACCCCAGGTTAATAAAGGGACTTAGCCAAAAAGAAAACGAATGAATGATGAATTCTAATCAGTGGTATATTTATTATTAACAAAATGTATGTTTTTTTTAAGGAATTCAATTTCCAAAATGCATTTATTGGGGCAAAAATACAGTGAATACTGTAAAATATGGTTACATTTCAAAATATCTTTTTTCTTTAAATATGCTTTAATAGGGTTTCTGCAGATGCTAATCTTACCTTTGTATTTAGCAGACACACTTGTCAAAAGCATCCTACAGTAAGAGAAGGCAGCAAGTAATTCATAATTAAAAAGCATAAAATGTTAAAATACACAGTTTATAAATCTGCTAGAA
Associated Phenotype:
Not determined